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Genetic and Environmental Factors in Autoimmune Thyroid Disease: Exploring Associations with Selenium Levels and Novel Loci in a Latvian Cohort
Curr Issues Mol Biol. 2024 Mar 17;46(3):2553-2565. doi: 10.3390/cimb46030162.ABSTRACTThe interplay of genetic, immune and environmental factors strongly contributes to the development of autoimmune thyroid disease (AITD), which can be classified as Graves' disease (GD) or Hashimoto thyroiditis (HT). One of the most studied exogenous factors in the pathogenesis of AITD is selenium, which, in the form of selenoproteins, strengthens the antioxidative defence system of thyroid cells against superoxide production. Furthermore, it modulates inflammatory cytokine release and autoantibody production. The aim of this study was to a...
Source: Current Issues in Molecular Biology - March 27, 2024 Category: Molecular Biology Authors: Sabine Upmale-Engela Ieva Vaivode Raitis Peculis Helena Litvina Tatjana Zake Andrejs Skesters Deniss Gogins Vita Rovite Ilze Konrade Source Type: research

Selenium enriched bifidobacteria and lactobacilli as potential dietary supplements
In this study, we tested the ability of lactobacilli and bifidobacteria strains to accumulate and biotransform sodium selenite into various selenium species, including selenium nanoparticles (SeNPs). Selenium tolerance and cytotoxicity of selenized strains towards human adenocarcinoma Caco-2 and HT29 cells were determined for all tested strains. Furthermore, the influence of selenium enrichment on the antioxidant activity of selenized strains and hydrophobicity of the bacterial cell surfaces were evaluated. Both hydrophobicity and antioxidant activity increased significantly in the selenizedL. paracasei strain and decrease...
Source: World Journal of Microbiology and Biotechnology - March 27, 2024 Category: Microbiology Source Type: research

Selenium and phosphide doped hollow porous N-doped carbon nanoboxes based electrospun N-doped carbon nanofibers toward electrochemical sensing of hydrogen peroxide
New J. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4NJ00091A, PaperFarzaneh Mohammadi, Mahmoud Roushani, Hadi Hosseini A new strategy for doping selenium and phosphide in the hollow N-doped carbon nanoboxes (N-CNBs)-based porous electrospun N-doped carbon nanofibers (CNFs) was developed. First, the lightweight N-CNBs was produced. Then,... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - March 26, 2024 Category: Chemistry Authors: Farzaneh Mohammadi Source Type: research

Nutritional impact of no-added sugar fruit puree consumption at different eating occasions: a modelling study on French children
CONCLUSION: Promoting NASFP in replacement of sweetened products is a promising strategy to improve the nutritional quality of French children's diet through a better adherence to national guidelines.PMID:38529770 | DOI:10.1017/S1368980024000739 (Source: Public Health Nutrition)
Source: Public Health Nutrition - March 26, 2024 Category: International Medicine & Public Health Authors: Romane Poinsot C éline Richonnet Florent Vieux Source Type: research

Molecular Regulatory Mechanism of Nano-Se Against Copper-Induced Spermatogenesis Disorder
In conclusion, this study confirmed that Nano-Se could alleviate oxidative stress, apoptosis, and DNA damage in the testis of mice with Cu excess, thereby protecting the spermatogenesis disorder induced by Cu.PMID:38528285 | DOI:10.1007/s12011-024-04153-0 (Source: Biological Trace Element Research)
Source: Biological Trace Element Research - March 26, 2024 Category: Biology Authors: Yujuan Ouyang Yanbing Lou Yanqiu Zhu Yihan Wang Song Zhu Lin Jing Tingting Yang Hengmin Cui Huidan Deng Zhicai Zuo Jing Fang Hongrui Guo Source Type: research