Efficacy of selenium on patients undergoing cardiac surgery: a meta-analysis of randomized controlled trials
Postoperative complications pose significant challenges in cardiac surgery and with the evolution of selenium as a potential anti-inflammatory agent, some studies reported its inefficiency. Thus, we conducted ... (Source: Journal of Cardiothoracic Surgery)
Source: Journal of Cardiothoracic Surgery - April 24, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Ahmed M. Sarhan, Ahmed K. Awad, Abdullah K. Alassiri, Mohamed Sameh Abd-Alkhaleq, Rahmeh Al-Asmar and Ahmed Reda Gonnah Tags: Review Source Type: research

GSE173219 High-throughput sequencing of oxidative stress for Human gastric cancer cell lines treatment with Bioactive polypeptide chelating selenium (ACBP-S-Se)
Contributor : Xiulan SuSeries Type : Expression profiling by high throughput sequencing ; Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensThe functional gene analyses revealed 911 upregulated genes and 1122 downregulated genes after ACBP-S-Se treatment in MKN-45 cells. From the functional enrichment analyses of oxidative stress-related genes, a total of 75 genes with significant differences were selected . From the gene interaction mapping, CDKN1A, CCNB1, TXN and MAP3K5 were extracted due to the roles of most genes with which they associate and to the significantly enriched pathways, which can...
Source: GEO: Gene Expression Omnibus - April 23, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Non-coding RNA profiling by high throughput sequencing Homo sapiens Source Type: research

Impact of different forms of selenium supplementation on growth and physiological performance of New Zealand white rabbits
AbstractForty-eight weaned male New Zealand White rabbits aged 6  weeks with an initial body weight of (709.67 ± 13 g) were randomly divided into six experimental groups (8 rabbits each) for 6–14 weeks of age experimental periods. The present study was planned to evaluate the effect of using different forms of Selenium element (inorganic, nanoparticles and organic) as dietary supplementation on productive performance of rabbits. Six experimental groups in completely randomized design were used. The first group (G1, control) was fed the basal diet to cover maintenance and production allowances. Rabbits in the othe...
Source: Tropical Animal Health and Production - April 19, 2024 Category: Veterinary Research Source Type: research

Continuous selenite biotransformation and biofuel production by marine diatom in the presence of fulvic acid
In this study, the biochemical response of Phaeodactylum tricornutum to varying concentrations of inorganic selenium (Se) was investigated. It was observed that, when combined with fulvic acid, P. tricornutum exhibited enhanced uptake and biotransformation of inorganic Se, as well as increased microalgal lipid biosynthesis. Notably, when subjected to moderate (5 and 10 mg/L) and high (20 and 40 mg/L) concentrations of selenite under fulvic acid treatment, there was a discernible redirection of carbon flux towards lipogenesis and protein biosynthesis from carbohydrates. In addition, the key parameters of microalgae-based bi...
Source: Bioresource Technology - April 18, 2024 Category: Biotechnology Authors: Hui-Ying Xu Ruo-Yu Li Zi-Qiang Yang Jia-Fan Qiu Yu-Bin Su Carol Sze Ki Lin Wei-Dong Yang Hong-Ye Li Jian-Wei Zheng Xiang Wang Source Type: research

Selenium bioactive compounds produced by beneficial microbes
Adv Appl Microbiol. 2024;126:63-92. doi: 10.1016/bs.aambs.2024.02.004. Epub 2024 Mar 29.ABSTRACTSelenium (Se) is an essential trace element present as selenocysteine (SeCys) in selenoproteins, which have an important role in thyroid metabolism and the redox system in humans. Se deficiency affects between 500 and 1000 million people worldwide. Increasing Se intake can prevent from bacterial and viral infections. Se deficiency has been associated with cancer, Alzheimer, Parkinson, decreased thyroid function, and male infertility. Se intake depends on the food consumed which is directly related to the amount of Se in the soil...
Source: Advances in Applied Microbiology - April 18, 2024 Category: Microbiology Authors: L Crespo B Sede Lucena F G Mart ínez F Mozzi M Pescuma Source Type: research

N-(3-((3-(trifluoromethyl)phenyl)selanyl)prop-2-yn-1-yl) benzamide induces antidepressant-like effect in mice: involvement of the serotonergic system
ConclusionThis study pointed a new compound with antidepressant-like effect, and it could be considered for the development of new antidepressants. (Source: Psychopharmacology)
Source: Psychopharmacology - April 18, 2024 Category: Psychiatry Source Type: research

Co-application of biochar and selenium nanoparticles improves yield and modifies fatty acid profile and essential oil composition of fennel (Foeniculum vulgare Mill.) under cadmium toxicity
Environ Sci Pollut Res Int. 2024 Apr 17. doi: 10.1007/s11356-024-33270-5. Online ahead of print.ABSTRACTFatty acids and essential oils (EOs) are the primary variables that influence the quality of fennel (Foeniculum vulgare Mill.). Soil toxicity to cadmium (Cd) is the main environmental issue facing fennel, and priming methods like soil amendments and nanoparticles (NPs) are commonly utilized to deal with it. The goal of the current study was to examine the effects of biochar (BC) and selenium nanoparticles (Se NPs) on fennel plants in Cd-contaminated soils. The pot experiment was conducted with Cd stress at 0, 10, and 20 ...
Source: Environmental Science and Pollution Research International - April 17, 2024 Category: Environmental Health Authors: Masoumeh Jahantigh Marzieh Ghanbari Jahromi Fatemeh Sefidkon Marjan Diyanat Weria Weisany Source Type: research

Early-age thermal manipulation and supplemental antioxidants on physiological, biochemical and productive performance of broiler chickens in hot-tropical environments
This study evaluated the effects of early-age thermal manipulation (EATC) and supplemental antioxidants on the physiological responses of broilers in a hot tropical environment. A total of 300 day-old Ross broiler chicks were allocated to five thermal and dietary treatments, having 5 replicates of twelve birds each. The treatments were: chicks reared using the conventional method (CC), chicks exposed to early thermal manipulation with a temperature of 38 °C at day 5 with no antioxidant supplementation (TC), TC plus vitamin E at 250 mg/kg of feed (TV), TC plus selenium at 0.5 mg/kg of feed (TS) and the combination of TS an...
Source: Stress - April 17, 2024 Category: Research Authors: Aderanti Ifeoluwa Oni John Adesanya Abiona Adeboye Olusesan Fafiolu Oyegunle Emmanuel Oke Source Type: research

Comparison of trace elements in peripheral blood and bone marrow of newly diagnosed multiple myeloma patients
In this study, we aimed to evaluate alterations in trace elements in the blood and bone marrow serum of patients with newly diagnosed multiple myeloma (NMM). The levels of zinc (Zn), copper (Cu), iron (Fe), manganese (Mn), magnesium (Mg), selenium (Se), arsenic (As), boron (B), nickel (Ni), silicon (Si) and chromium (Cr) were analyzed in the venous blood samples of the patient group comprising 70 patients with NMM (41 males and 29 females) and compared to those in the control group comprising 30 individuals (18 males and 12 females). In addition, trace element levels were analyzed in bone marrow samples from the patient gr...
Source: Cancer Control - April 17, 2024 Category: Cancer & Oncology Authors: Ayse Nilgun Kul Bahar Ozturk Kurt Source Type: research

A Comprehensive Review on GLP-1 Signaling Pathways in the Management of Diabetes Mellitus - Focus on the Potential Role of GLP-1 Receptors Agonists and Selenium Among Various Organ Systems
Curr Diabetes Rev. 2024 Apr 16. doi: 10.2174/0115733998287178240403055901. Online ahead of print.ABSTRACTDiabetes Mellitus develops when the body becomes unable to fuel its cells with glucose, which results in the accumulation of sugar excess in the bloodstream. Because it has diverse pathophysiological impacts on the body, diabetes mellitus represents a significant issue of concern in an attempt to find suitable treatment modalities and medications for afflicted diabetic patients. Glucagon-like peptide 1 (GLP-1) plays a pivotal role in the incretin effect, emerging as a prospective treatment for diabetes mellitus and a pr...
Source: Current Diabetes Reviews - April 17, 2024 Category: Endocrinology Authors: Ghinwa Barakat Ghaith Assi Hussein Khalil Sami El Khatib Source Type: research

Co-application of biochar and selenium nanoparticles improves yield and modifies fatty acid profile and essential oil composition of fennel (Foeniculum vulgare Mill.) under cadmium toxicity
Environ Sci Pollut Res Int. 2024 Apr 17. doi: 10.1007/s11356-024-33270-5. Online ahead of print.ABSTRACTFatty acids and essential oils (EOs) are the primary variables that influence the quality of fennel (Foeniculum vulgare Mill.). Soil toxicity to cadmium (Cd) is the main environmental issue facing fennel, and priming methods like soil amendments and nanoparticles (NPs) are commonly utilized to deal with it. The goal of the current study was to examine the effects of biochar (BC) and selenium nanoparticles (Se NPs) on fennel plants in Cd-contaminated soils. The pot experiment was conducted with Cd stress at 0, 10, and 20 ...
Source: Environmental Science and Pollution Research International - April 17, 2024 Category: Environmental Health Authors: Masoumeh Jahantigh Marzieh Ghanbari Jahromi Fatemeh Sefidkon Marjan Diyanat Weria Weisany Source Type: research

Early-age thermal manipulation and supplemental antioxidants on physiological, biochemical and productive performance of broiler chickens in hot-tropical environments
This study evaluated the effects of early-age thermal manipulation (EATC) and supplemental antioxidants on the physiological responses of broilers in a hot tropical environment. A total of 300 day-old Ross broiler chicks were allocated to five thermal and dietary treatments, having 5 replicates of twelve birds each. The treatments were: chicks reared using the conventional method (CC), chicks exposed to early thermal manipulation with a temperature of 38 °C at day 5 with no antioxidant supplementation (TC), TC plus vitamin E at 250 mg/kg of feed (TV), TC plus selenium at 0.5 mg/kg of feed (TS) and the combination of TS an...
Source: Stress - April 17, 2024 Category: Research Authors: Aderanti Ifeoluwa Oni John Adesanya Abiona Adeboye Olusesan Fafiolu Oyegunle Emmanuel Oke Source Type: research

A Comprehensive Review on GLP-1 Signaling Pathways in the Management of Diabetes Mellitus - Focus on the Potential Role of GLP-1 Receptors Agonists and Selenium Among Various Organ Systems
Curr Diabetes Rev. 2024 Apr 16. doi: 10.2174/0115733998287178240403055901. Online ahead of print.ABSTRACTDiabetes Mellitus develops when the body becomes unable to fuel its cells with glucose, which results in the accumulation of sugar excess in the bloodstream. Because it has diverse pathophysiological impacts on the body, diabetes mellitus represents a significant issue of concern in an attempt to find suitable treatment modalities and medications for afflicted diabetic patients. Glucagon-like peptide 1 (GLP-1) plays a pivotal role in the incretin effect, emerging as a prospective treatment for diabetes mellitus and a pr...
Source: Current Diabetes Reviews - April 17, 2024 Category: Endocrinology Authors: Ghinwa Barakat Ghaith Assi Hussein Khalil Sami El Khatib Source Type: research

Comparison of trace elements in peripheral blood and bone marrow of newly diagnosed multiple myeloma patients
In this study, we aimed to evaluate alterations in trace elements in the blood and bone marrow serum of patients with newly diagnosed multiple myeloma (NMM). The levels of zinc (Zn), copper (Cu), iron (Fe), manganese (Mn), magnesium (Mg), selenium (Se), arsenic (As), boron (B), nickel (Ni), silicon (Si) and chromium (Cr) were analyzed in the venous blood samples of the patient group comprising 70 patients with NMM (41 males and 29 females) and compared to those in the control group comprising 30 individuals (18 males and 12 females). In addition, trace element levels were analyzed in bone marrow samples from the patient gr...
Source: Clinical and Experimental Medicine - April 17, 2024 Category: Research Source Type: research