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Drug: Aspirin
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Total 5437 results found since Jan 2013.
Platelets and neutrophils cooperate to induce increased NETosis in JAK2V617F myeloproliferative neoplasms
CONCLUSIONS: Our study demonstrates that JAK2V617F neutrophils alone are not sufficient to promote thrombosis; rather, platelets cooperate with neutrophils to promote NETosis in vivo. A new role for aspirin in thrombosis prevention in MPNs was also identified.PMID:37678548 | DOI:10.1016/j.jtha.2023.08.028
Source: Thrombosis and Haemostasis - September 7, 2023 Category: Hematology Authors: Alexandre Guy Geoffrey Garcia Virginie Gourdou-Latyszenok Laura Wolff-Thrombini Lara Josserand Quentin Kimmerlin Simon Favre Badr Kilani Caroline Marty Yacine Boulaftali Sylvie Labrouche-Colomer Olivier Mansier Chlo é James Source Type: research
Propensity score analysis of low dose aspirin and bleeding complications in pregnancy
CONCLUSIONS: Low dose aspirin recommendation in pregnancy was associated with increased risk for placental abruption and for postpartum hemorrhage. Our results support the need for more research into aspirin and bleeding complications in pregnancy before recommending it beyond the highest risk pregnancies. This article is protected by copyright. All rights reserved.PMID:37674400 | DOI:10.1002/uog.27472
Source: The Ultrasound Review of Obstetrics and Gynecology - September 7, 2023 Category: Radiology Authors: V Souter I Painter K Sitcov A Khalil Source Type: research
Spent tea waste extract as a green modifying agent of chitosan for aspirin adsorption: Fixed-bed column, modeling and toxicity studies
Int J Biol Macromol. 2023 Sep 5:126501. doi: 10.1016/j.ijbiomac.2023.126501. Online ahead of print.ABSTRACTAspirin is a prevalent over-the-counter medicine that has been categorized as an emerging contaminant due to its danger to both living things and the environment. This work presents chitosan modified with spent tea waste extract (STWE) via the wet impregnation method as an adsorbent for the enhanced removal of aspirin in a fixed-bed column. The adsorbent (named chitosan-STWE) was successfully synthesized and exhibited a low crystallinity structure, good stability against thermal and acidic conditions, as depicted by H...
Source: International Journal of Biological Macromolecules - September 7, 2023 Category: Biochemistry Authors: Abu Hassan Nordin Norzita Ngadi Muhammad Luqman Nordin Nur Amalina Noralidin Walid Nabgan Abdinasir Yusuf Osman Rumaizi Shaari Source Type: research
Propensity score analysis of low dose aspirin and bleeding complications in pregnancy
CONCLUSIONS: Low dose aspirin recommendation in pregnancy was associated with increased risk for placental abruption and for postpartum hemorrhage. Our results support the need for more research into aspirin and bleeding complications in pregnancy before recommending it beyond the highest risk pregnancies. This article is protected by copyright. All rights reserved.PMID:37674400 | DOI:10.1002/uog.27472
Source: The Ultrasound Review of Obstetrics and Gynecology - September 7, 2023 Category: Radiology Authors: V Souter I Painter K Sitcov A Khalil Source Type: research
Spent tea waste extract as a green modifying agent of chitosan for aspirin adsorption: Fixed-bed column, modeling and toxicity studies
Int J Biol Macromol. 2023 Sep 5:126501. doi: 10.1016/j.ijbiomac.2023.126501. Online ahead of print.ABSTRACTAspirin is a prevalent over-the-counter medicine that has been categorized as an emerging contaminant due to its danger to both living things and the environment. This work presents chitosan modified with spent tea waste extract (STWE) via the wet impregnation method as an adsorbent for the enhanced removal of aspirin in a fixed-bed column. The adsorbent (named chitosan-STWE) was successfully synthesized and exhibited a low crystallinity structure, good stability against thermal and acidic conditions, as depicted by H...
Source: International Journal of Biological Macromolecules - September 7, 2023 Category: Biochemistry Authors: Abu Hassan Nordin Norzita Ngadi Muhammad Luqman Nordin Nur Amalina Noralidin Walid Nabgan Abdinasir Yusuf Osman Rumaizi Shaari Source Type: research
11,12-seco-Abietane-type diterpene lactones with potential antiplatelet activity from Salvia prattii
Bioorg Chem. 2023 Sep 2;140:106834. doi: 10.1016/j.bioorg.2023.106834. Online ahead of print.ABSTRACTEleven new abietane-type diterpene lactones, salpratlactones D-N (1-11), including five 11,12-seco-11-nor-abietane diterpenes (1-5), four 11,12-seco-abietane diterpenes (6-9), two 20(10 → 5)-abeo-4,5;11,12-bis-seco-abietane diterpenes (10-11), and two known analogues (12-13), were characterized from Salvia prattii. Notably, compounds 1-3 were characterized by a unique linear 6/6/6 tricyclic skeleton. The structures were established by spectroscopic data interpretation, calculated NMR-DP4+ and electronic circular dichroism...
Source: Bioorganic Chemistry - September 7, 2023 Category: Chemistry Authors: Fan Xia Li-Sha Lin Yan-Song Ye Lian Yang Jin-Hua Zhao Gang Xu Source Type: research
Propensity score analysis of low dose aspirin and bleeding complications in pregnancy
CONCLUSIONS: Low dose aspirin recommendation in pregnancy was associated with increased risk for placental abruption and for postpartum hemorrhage. Our results support the need for more research into aspirin and bleeding complications in pregnancy before recommending it beyond the highest risk pregnancies. This article is protected by copyright. All rights reserved.PMID:37674400 | DOI:10.1002/uog.27472
Source: The Ultrasound Review of Obstetrics and Gynecology - September 7, 2023 Category: Radiology Authors: V Souter I Painter K Sitcov A Khalil Source Type: research
11,12-seco-Abietane-type diterpene lactones with potential antiplatelet activity from Salvia prattii
Bioorg Chem. 2023 Sep 2;140:106834. doi: 10.1016/j.bioorg.2023.106834. Online ahead of print.ABSTRACTEleven new abietane-type diterpene lactones, salpratlactones D-N (1-11), including five 11,12-seco-11-nor-abietane diterpenes (1-5), four 11,12-seco-abietane diterpenes (6-9), two 20(10 → 5)-abeo-4,5;11,12-bis-seco-abietane diterpenes (10-11), and two known analogues (12-13), were characterized from Salvia prattii. Notably, compounds 1-3 were characterized by a unique linear 6/6/6 tricyclic skeleton. The structures were established by spectroscopic data interpretation, calculated NMR-DP4+ and electronic circular dichroism...
Source: Bioorganic Chemistry - September 7, 2023 Category: Chemistry Authors: Fan Xia Li-Sha Lin Yan-Song Ye Lian Yang Jin-Hua Zhao Gang Xu Source Type: research
The chronic rhinosinusitis practice parameter
Ann Allergy Asthma Immunol. 2023 Sep;131(3):307-310. doi: 10.1016/j.anai.2022.12.022. Epub 2022 Dec 17.ABSTRACTThe Allergy-Immunology Joint Task Force on Practice Parameters has published the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) guidelines for the medical management of chronic rhinosinusitis with nasal polyposis (CRSwNP). The practice parameter provides evidence-based guidelines on the use of intranasal corticosteroids (INCS) and biologics for CRSwNP, and aspirin therapy after desensitization (ATAD) for the management of aspirin-exacerbated respiratory disease (AERD). Evidence on surge...
Source: Annals of Allergy, Asthma and Immunology - September 5, 2023 Category: Allergy & Immunology Authors: So Lim Kim Matthew A Rank Anju Tripathi Peters Source Type: research
Aspirin for primary prevention in patients with high cardiovascular risk: insights from CORE-Thailand registry
Sci Rep. 2023 Sep 5;13(1):14646. doi: 10.1038/s41598-023-41864-1.ABSTRACTAspirin may be considered for primary prevention in non-elderly patients with high cardiovascular risk. However, contemporary management aimed at aggressive cardiovascular risk factor control may alter benefit-risk ratio of aspirin. Therefore, we aimed to examine the effect of aspirin for primary prevention on the long-term MACEs in a large cohort registry. Cohort Of patients with high Risk for cardiovascular Events (CORE-Thailand) registry is a prospective, multicenter, observational, longitudinal study of Thai patients with high atherosclerotic risk...
Source: Atherosclerosis - September 5, 2023 Category: Cardiology Authors: Wanwarang Wongcharoen Nichanan Osataphan Narawudt Prasertwitayakij Pannipa Suwannasom Swangjit Suraamornkul Wattana Wongtheptian Siriluck Gunaparn Wachiranun Sirikul Arintaya Phrommintikul Source Type: research
Aspirin for those at high risk: when to stop?
BJOG. 2023 Sep 3. doi: 10.1111/1471-0528.17644. Online ahead of print.NO ABSTRACTPMID:37661295 | DOI:10.1111/1471-0528.17644
Source: BJOG : An International Journal of Obstetrics and Gynaecology - September 4, 2023 Category: OBGYN Authors: David Wright Kypros H Nicolaides Source Type: research
Metformin and Aspirin: Anticancer effects on A549 and PC3 cancer cells and the mechanisms of action
This study aims to investigate the effect of metformin and aspirin and their combination of them on A549 and PC3 cell lines. Metformin and aspirin were investigated separately and in combination on two cancer cell lines, A549 and PC3. The examined groups include the negative control of untreated cells and the positive control of cisplatin and drugs at concentrations of 15, 10, and 20 μg/ mL to investigate the mechanism of oxidative stress factors (reactive oxygen species, lipid peroxidation, Glutathione (GSH)) and apoptosis (lactate dehydrogenase). The results showed that aspirin, metformin, and their combination could af...
Source: Cancer Control - September 4, 2023 Category: Cancer & Oncology Authors: Farzaneh Motafeghi Romina Shahsavari Parham Mortazavi Aysan Babaei Pouria SamadiMojaveri Omid Abed Khojasteh Mohammad Shokrzadeh Source Type: research
