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Drug: Aspirin
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Impact of Atrial Fibrillation on Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI): The K-TAVI Registry
CONCLUSION: AF was an independent predictor of 1-year mortality and new pacemaker insertion in Korean patients undergoing TAVI.PMID:37365735 | PMC:PMC10307679 | DOI:10.3349/ymj.2022.0649
Source: Yonsei Medical Journal - June 27, 2023 Category: Universities & Medical Training Authors: Sang Yoon Lee Ki Hong Choi Taek Kyu Park Jihoon Kim Eun Kyoung Kim Sung-Ji Park Seung Woo Park Hyeon-Cheol Gwon Kiyuk Chang Cheol Woong Yu JuHan Kim Young Jin Choi In-Ho Chae Jae-Hwan Lee Jun-Hong Kim Jong Seon Park Won-Jang Kim Young Won Yoon Tae Hoon Ah Source Type: research
DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells
Curr Issues Mol Biol. 2023 May 28;45(6):4665-4674. doi: 10.3390/cimb45060296.ABSTRACTRepositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation to maintain a malignant phenotype, and the mechanistic target of rapamycin (mTORC1) is required for lipogenesis. We, therefore, aimed to test if the expression of mTORC1 suppressor DNA damage-inducible transcript (DDIT4) affects the activity of...
Source: Current Issues in Molecular Biology - June 27, 2023 Category: Molecular Biology Authors: Aist ė Savukaitytė Agn ė Bartnykaitė Justina Bekampyt ė Rasa Ugenskien ė Elona Juozaityt ė Source Type: research
Impact of Atrial Fibrillation on Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI): The K-TAVI Registry
CONCLUSION: AF was an independent predictor of 1-year mortality and new pacemaker insertion in Korean patients undergoing TAVI.PMID:37365735 | PMC:PMC10307679 | DOI:10.3349/ymj.2022.0649
Source: Yonsei Medical Journal - June 27, 2023 Category: Universities & Medical Training Authors: Sang Yoon Lee Ki Hong Choi Taek Kyu Park Jihoon Kim Eun Kyoung Kim Sung-Ji Park Seung Woo Park Hyeon-Cheol Gwon Kiyuk Chang Cheol Woong Yu JuHan Kim Young Jin Choi In-Ho Chae Jae-Hwan Lee Jun-Hong Kim Jong Seon Park Won-Jang Kim Young Won Yoon Tae Hoon Ah Source Type: research
DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells
Curr Issues Mol Biol. 2023 May 28;45(6):4665-4674. doi: 10.3390/cimb45060296.ABSTRACTRepositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation to maintain a malignant phenotype, and the mechanistic target of rapamycin (mTORC1) is required for lipogenesis. We, therefore, aimed to test if the expression of mTORC1 suppressor DNA damage-inducible transcript (DDIT4) affects the activity of...
Source: Current Issues in Molecular Biology - June 27, 2023 Category: Molecular Biology Authors: Aist ė Savukaitytė Agn ė Bartnykaitė Justina Bekampyt ė Rasa Ugenskien ė Elona Juozaityt ė Source Type: research
Impact of Atrial Fibrillation on Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI): The K-TAVI Registry
CONCLUSION: AF was an independent predictor of 1-year mortality and new pacemaker insertion in Korean patients undergoing TAVI.PMID:37365735 | PMC:PMC10307679 | DOI:10.3349/ymj.2022.0649
Source: Yonsei Medical Journal - June 27, 2023 Category: Universities & Medical Training Authors: Sang Yoon Lee Ki Hong Choi Taek Kyu Park Jihoon Kim Eun Kyoung Kim Sung-Ji Park Seung Woo Park Hyeon-Cheol Gwon Kiyuk Chang Cheol Woong Yu JuHan Kim Young Jin Choi In-Ho Chae Jae-Hwan Lee Jun-Hong Kim Jong Seon Park Won-Jang Kim Young Won Yoon Tae Hoon Ah Source Type: research
DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells
Curr Issues Mol Biol. 2023 May 28;45(6):4665-4674. doi: 10.3390/cimb45060296.ABSTRACTRepositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation to maintain a malignant phenotype, and the mechanistic target of rapamycin (mTORC1) is required for lipogenesis. We, therefore, aimed to test if the expression of mTORC1 suppressor DNA damage-inducible transcript (DDIT4) affects the activity of...
Source: Current Issues in Molecular Biology - June 27, 2023 Category: Molecular Biology Authors: Aist ė Savukaitytė Agn ė Bartnykaitė Justina Bekampyt ė Rasa Ugenskien ė Elona Juozaityt ė Source Type: research
Impact of Atrial Fibrillation on Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI): The K-TAVI Registry
CONCLUSION: AF was an independent predictor of 1-year mortality and new pacemaker insertion in Korean patients undergoing TAVI.PMID:37365735 | PMC:PMC10307679 | DOI:10.3349/ymj.2022.0649
Source: Yonsei Medical Journal - June 27, 2023 Category: Universities & Medical Training Authors: Sang Yoon Lee Ki Hong Choi Taek Kyu Park Jihoon Kim Eun Kyoung Kim Sung-Ji Park Seung Woo Park Hyeon-Cheol Gwon Kiyuk Chang Cheol Woong Yu JuHan Kim Young Jin Choi In-Ho Chae Jae-Hwan Lee Jun-Hong Kim Jong Seon Park Won-Jang Kim Young Won Yoon Tae Hoon Ah Source Type: research
DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells
Curr Issues Mol Biol. 2023 May 28;45(6):4665-4674. doi: 10.3390/cimb45060296.ABSTRACTRepositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation to maintain a malignant phenotype, and the mechanistic target of rapamycin (mTORC1) is required for lipogenesis. We, therefore, aimed to test if the expression of mTORC1 suppressor DNA damage-inducible transcript (DDIT4) affects the activity of...
Source: Current Issues in Molecular Biology - June 27, 2023 Category: Molecular Biology Authors: Aist ė Savukaitytė Agn ė Bartnykaitė Justina Bekampyt ė Rasa Ugenskien ė Elona Juozaityt ė Source Type: research
Impact of Atrial Fibrillation on Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI): The K-TAVI Registry
CONCLUSION: AF was an independent predictor of 1-year mortality and new pacemaker insertion in Korean patients undergoing TAVI.PMID:37365735 | PMC:PMC10307679 | DOI:10.3349/ymj.2022.0649
Source: Yonsei Medical Journal - June 27, 2023 Category: Universities & Medical Training Authors: Sang Yoon Lee Ki Hong Choi Taek Kyu Park Jihoon Kim Eun Kyoung Kim Sung-Ji Park Seung Woo Park Hyeon-Cheol Gwon Kiyuk Chang Cheol Woong Yu JuHan Kim Young Jin Choi In-Ho Chae Jae-Hwan Lee Jun-Hong Kim Jong Seon Park Won-Jang Kim Young Won Yoon Tae Hoon Ah Source Type: research
DDIT4 Downregulation by siRNA Approach Increases the Activity of Proteins Regulating Fatty Acid Metabolism upon Aspirin Treatment in Human Breast Cancer Cells
Curr Issues Mol Biol. 2023 May 28;45(6):4665-4674. doi: 10.3390/cimb45060296.ABSTRACTRepositioning of aspirin for a more effective breast cancer (BC) treatment requires identification of predictive biomarkers. However, the molecular mechanism underlying the anticancer activity of aspirin remains fully undefined. Cancer cells enhance de novo fatty acid (FA) synthesis and FA oxidation to maintain a malignant phenotype, and the mechanistic target of rapamycin (mTORC1) is required for lipogenesis. We, therefore, aimed to test if the expression of mTORC1 suppressor DNA damage-inducible transcript (DDIT4) affects the activity of...
Source: Current Issues in Molecular Biology - June 27, 2023 Category: Molecular Biology Authors: Aist ė Savukaitytė Agn ė Bartnykaitė Justina Bekampyt ė Rasa Ugenskien ė Elona Juozaityt ė Source Type: research
