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Drug: Aspirin

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Total 5437 results found since Jan 2013.

Correction: Effect of Low-Dose Aspirin Versus Placebo on Incidence of Anemia in the Elderly
Ann Intern Med. 2023 Jul 25. doi: 10.7326/L23-0274. Online ahead of print.NO ABSTRACTPMID:37487218 | DOI:10.7326/L23-0274
Source: Annals of Internal Medicine - July 24, 2023 Category: Internal Medicine Source Type: research

Targeting beta-catenin signaling for prevention of colorectal cancer - Nutraceutical, drug, and dietary options
Eur J Pharmacol. 2023 Jul 20:175898. doi: 10.1016/j.ejphar.2023.175898. Online ahead of print.ABSTRACTProgressive up-regulation of β-catenin signaling is very common in the transformation of colorectal epithelium to colorectal cancer (CRC). Practical measures for opposing such signaling hence have potential for preventing or slowing such transformation. cAMP/PKA activity in colon epithelium, as stimulated by COX-2-generated prostaglandins and β2-adrenergic signaling, boosts β-catenin activity, whereas cGMP/PKG signaling has the opposite effect. Bacterial generation of short-chain fatty acids (as supported by unrefined h...
Source: European Journal of Pharmacology - July 22, 2023 Category: Drugs & Pharmacology Authors: Simon Bernard Iloki Assanga Lidianys Mar ía Lewis Luján Mark F McCarty Source Type: research

The Effect of Corticosteroids on Sinus Microbiota in Chronic Rhinosinusitis Patients with Nasal Polyposis
CONCLUSION: In this pilot study, both treatment options were effective to improve symptoms in the short-term but not in the long-term, and were not linked to any clear sinus microbiota response. As a result, this study supports the avoidance of systemic antibiotics without evidence of active infection.PMID:37475202 | DOI:10.1177/19458924231183848
Source: American Journal of Rhinology and Allergy - July 21, 2023 Category: ENT & OMF Authors: Yousif Alammar Simon Rousseau Martin Desrosiers Marc A Tewfik Source Type: research

The Role of Platelets in Non-Alcoholic Fatty Liver Disease: From Pathophysiology to Therapeutics
Prostaglandins Other Lipid Mediat. 2023 Jul 19:106766. doi: 10.1016/j.prostaglandins.2023.106766. Online ahead of print.ABSTRACTPlatelets are one of the key mediators in thrombosis as well as in the progression of many diseases. An increase in platelet activation and a decrease in platelet count is associated with a plethora of liver diseases. In non-alcoholic fatty liver disease (NAFLD), platelets are highly activated and participate in the disease progression by enhancing the pro-thrombotic and pro-inflammatory state. Some altered platelet parameters such as mean platelet volume, plateletcrits, and platelet distribution ...
Source: Atherosclerosis - July 21, 2023 Category: Cardiology Authors: Malladi Navya Md Jahangir Alam Subir K Maulik Sanjay K Banerjee Source Type: research

The Effect of Corticosteroids on Sinus Microbiota in Chronic Rhinosinusitis Patients with Nasal Polyposis
CONCLUSION: In this pilot study, both treatment options were effective to improve symptoms in the short-term but not in the long-term, and were not linked to any clear sinus microbiota response. As a result, this study supports the avoidance of systemic antibiotics without evidence of active infection.PMID:37475202 | DOI:10.1177/19458924231183848
Source: American Journal of Rhinology and Allergy - July 21, 2023 Category: ENT & OMF Authors: Yousif Alammar Simon Rousseau Martin Desrosiers Marc A Tewfik Source Type: research

Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: A secondary analysis of the ASPIRIN trial
CONCLUSIONS: In this secondary analysis of a study of low-risk nulliparous singleton pregnancies, early administration of LDA resulted in lower rates of preterm HDP and delivery before 34 and 37 weeks but not in the overall rate of HDP. These results suggest that LDA works in part by delaying HDP.PMID:37470099 | DOI:10.1111/1471-0528.17607
Source: BJOG : An International Journal of Obstetrics and Gynaecology - July 20, 2023 Category: OBGYN Authors: Avinash Kavi Matthew K Hoffman Manjunath S Somannavar Mrityunjay C Metgud Shivaprasad S Goudar Janet Moore Eleanor Nielsen Norman Goco Elizabeth M McClure Adrien Lokangaka Antoinette Tshefu Melissa Bauserman Musaku Mwenechanya Elwyn Chomba Waldemar A Carl Source Type: research