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Therapy: Hyperbaric Oxygen Therapy

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Total 340 results found since Jan 2013.

Hyperbaric oxygen therapy in acute stroke: is it time for Justitia to open her eyes?
AbstractHypoxia is a critical component of neuronal death in patients with stroke. Therefore increasing oxygenation of brain tissue seems to be a logical therapy against cerebral ischemia. Oxygen therapy exists in two modalities: normobaric hyperoxia therapy and hyperbaric oxygen therapy (HBO). HBO is a therapeutic procedure in which pure (100%) oxygen is administered at greater than atmospheric pressure in HBO therapy chambers. In this review article, we aimed to summarize the current knowledge regarding the therapeutic use of HBO in acute stroke patients. Literature review and electronic search were performed using PubMe...
Source: Neurological Sciences - January 10, 2020 Category: Neurology Source Type: research

Long-term functional prognosis of patients with aneurysmal subarachnoid hemorrhage treated with rehabilitation combined with hyperbaric oxygen: Case-series study
The long-term prognosis of patients with aneurysmal subarachnoid hemorrhage (aSAH) has received increasing attention in recent years. Hyperbaric oxygen and rehabilitation are already used in clinical treatment of patients with aSAH, but it is unclear whether it can improve the long-term prognosis of patients postoperation. The purpose of this study was to evaluate the long-term prognosis and prognostic factors associated with combined rehabilitation and hyperbaric oxygen therapy for patients with aSAH. Information were retrospectively collected from patients with aSAH treated from October 2014 to July 2017, including demo...
Source: Medicine - January 1, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Higher versus lower fraction of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit.
CONCLUSIONS: We are very uncertain about the effects of higher versus lower fraction of inspired oxygen or targets of arterial oxygenation for adults admitted to the ICU on all-cause mortality, serious adverse events, and lung injuries at the time point closest to three months due to very low-certainty evidence. Our results indicate that oxygen supplementation with higher versus lower fractions or oxygenation targets may increase mortality. None of the trials reported the proportion of participants with one or more serious adverse events according to the ICH-GCP criteria, however we found that the trials reported an increa...
Source: Cochrane Database of Systematic Reviews - November 26, 2019 Category: General Medicine Authors: Barbateskovic M, Schjørring OL, Russo Krauss S, Jakobsen JC, Meyhoff CS, Dahl RM, Rasmussen BS, Perner A, Wetterslev J Tags: Cochrane Database Syst Rev Source Type: research

Cerebral Air Embolism after Esophagogastroduodenoscopy: Insight on Pathophysiology, Epidemiology, Prevention and Treatment
Air embolism is an extremely rare complication that can follow gastrointestinal endoscopy. The most accepted treatment of cerebral air embolism (CAE) is hyperbaric oxygen (HBO). Limited evidence suggests that lidocaine may have a neuroprotective effect. The exact mechanism does not appear to be well elucidated.
Source: Journal of Stroke and Cerebrovascular Diseases - September 25, 2019 Category: Neurology Authors: Malik Ghannam, Azizullah Beran, Dana Ghazaleh, Tanner Ferderer, Brent Berry, Mona Al Banna, Leighton Mohl, Christopher Streib, Tapan Thacker, Ivan Matos Source Type: research

Hyperbaric oxygen therapy in ischemic stroke management: Standardized consensus-based therapeutic protocol
Guru Dutta SatyartheeNeurology India 2019 67(3):653-654
Source: Neurology India - July 22, 2019 Category: Neurology Authors: Guru Dutta Satyarthee Source Type: research

Hypothalamic impairment underlying heat intolerance in pregnant mice
In conclusion, pregnancy induces heat intolerance by inducing hypothalamic impairment in mice. Additionally, HBO2T protects against heat intolerance in pregnant mice by preserving hypothalamic integrity.
Source: Molecular and Cellular Endocrinology - May 6, 2019 Category: Endocrinology Source Type: research

Prophylactic treatment of hyperbaric oxygen treatment mitigates inflammatory response via mitochondria transfer.
CONCLUSION: This study shows that HBOT preconditioning stands as a robust prophylactic treatment for sequestration of inflammation inherent in stroke and TBI, possibly facilitating the transfer of resilient mitochondria from astrocytes to inflammation-susceptible neuronal cells in mitigating cell death. PMID: 30972972 [PubMed - as supplied by publisher]
Source: CNS Neuroscience and Therapeutics - April 10, 2019 Category: Neuroscience Authors: Lippert T, Borlongan CV Tags: CNS Neurosci Ther Source Type: research

Review of the Current Knowledge on the Role of Stem Cell Transplantation in Neurorehabilitation.
Abstract The management involving stem cell (SC) therapy along with physiotherapy offers tremendous chance for patients after spinal cord injury (SCI), traumatic brain injury (TBI), stroke, etc. However, there are still only a limited number of reports assessing the impact of stem cells (SCs) on the rehabilitation process and/or the results of the simultaneous use of SC and rehabilitation. Additionally, since there is still not enough convincing evidence about the effect of SCT on humans, e.g., in stroke, there have been no studies conducted concerning rehabilitation program formation and expected outcomes. It has...
Source: Biomed Res - April 3, 2019 Category: Research Authors: Kamelska-Sadowska AM, Wojtkiewicz J, Kowalski IM Tags: Biomed Res Int Source Type: research

South Africa: Quack Claims About Oxygen Treatment Are Dangerous
[GroundUp] If you go scuba-diving and come up to the surface too fast, you might need Hyperbaric Oxygen Therapy. But, experts warn, it can't treat cancer, stroke, Alzheimer's disease, autism, or arthritis, as some quack outfits are claiming.
Source: AllAfrica News: Health and Medicine - March 15, 2019 Category: African Health Source Type: news

Neuroprotective Autophagic Flux Induced by Hyperbaric Oxygen Preconditioning is Mediated by Cystatin C
AbstractWe have previously reported that Cystatin C (CysC) is a pivotal mediator in the neuroprotection induced by hyperbaric oxygen (HBO) preconditioning; however, the underlying mechanism and how CysC changes after stroke are not clear. In the present study, we demonstrated that CysC expression was elevated as early as 3  h after reperfusion, and this was further enhanced by HBO preconditioning. Concurrently, LC3-II and Beclin-1, two positive-markers for autophagy induction, exhibited increases similar to CysC, while knockdown of CysC blocked these elevations. As a marker of autophagy inhibition, p62 was downregula ted ...
Source: Neuroscience Bulletin - December 5, 2018 Category: Neuroscience Source Type: research

The Effect of Hyperbaric Oxygen Therapy on Functional Impairments Caused by Ischemic Stroke.
Conclusions: Findings from this study support the idea of HBOT as a potential intervention following stroke. PMID: 30402285 [PubMed]
Source: Neurology Research International - November 9, 2018 Category: Neurology Tags: Neurol Res Int Source Type: research

Increased circulating endothelial progenitor cells and improved short-term outcomes in acute non-cardioembolic stroke after hyperbaric oxygen therapy
This study tested the hypothesi...
Source: Journal of Translational Medicine - September 12, 2018 Category: Research Authors: Chen-Yu Chen, Re-Wen Wu, Nai-Wen Tsai, Mel S. Lee, Wei-Che Lin, Mei-Chi Hsu, Chih-Cheng Huang, Yun-Ru Lai, Chia-Te Kung, Hung-Chen Wang, Yu-Jih Su, Chih-Min Su, Sheng-Yuan Hsiao, Ben-Chung Cheng, Yi-Fang Chiang and Cheng-Hsien Lu Tags: Research Source Type: research

Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis
This study is registered with PROSPERO, number CRD42017065697. Findings 25 randomised controlled trials enrolled 16 037 patients with sepsis, critical illness, stroke, trauma, myocardial infarction, or cardiac arrest, and patients who had emergency surgery. Compared with a conservative oxygen strategy, a liberal oxygen strategy (median baseline saturation of peripheral oxygen [SpO2] across trials, 96% [range 94–99%, IQR 96–98]) increased mortality in-hospital (relative risk [RR] 1·21, 95% CI 1·03–1·43, I 2=0%, high quality), at 30 days (RR 1·14, 95% CI 1·01–1·29, I 2=0%, high quality), and at longest follow...
Source: The Lancet - April 28, 2018 Category: General Medicine Source Type: research

The neuroprotection effect of oxygen therapy: A systematic review and meta-analysis
This study reviews the oxygen therapy (normobaric oxygen [NBO] and hyperbaric oxygen [HBO]) in both stroke and traumatic brain injury (TBI) patients and meta-analyzes the efficacy of two oxygen therapies in different kinds of injuries. In stroke patients, NBO showed significant improvement in reperfusion rate while there is no favorable outcome effect of HBO treatment. In patients with TBI, HBO showed significant improvement of Glasgow outcome scale score and reduction of overall mortality while NBO may play a favorable role in improving brain metabolism.
Source: Nigerian Journal of Clinical Practice - April 2, 2018 Category: Rural Health Authors: Z Deng W Chen J Jin J Zhao H Xu Source Type: research

Acute Ischemic Stroke in a Young Woman With No Known Risk Factors.
CONCLUSION: Onset of neurologic symptoms can be immediate or delayed in patients undergoing venous foam sclerotherapy. Early recognition of neurologic deficits resulting from paradoxical gas embolism and its treatment with hyperbaric oxygen can prevent permanent disability. PMID: 29677415 [PubMed - in process]
Source: WMJ - March 1, 2018 Category: General Medicine Authors: Abdelhamid N, Farooq S, Sarraj A Tags: WMJ Source Type: research