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Specialty: Cardiology
Procedure: Transplants

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Total 261 results found since Jan 2013.

A decade of cardiac transplantation in Coimbra: The value of experience
Conclusion This 10-year series yielded results equivalent or superior to those of centers with wider and longer experience, and have progressively improved following the introduction of changes prompted by experience. This program has made it possible to raise and maintain the rate of heart transplantation to values above the European average.
Source: Revista Portuguesa de Cardiologia - November 21, 2014 Category: Cardiology Source Type: research

Clinical Outcomes After Continuous-Flow Left Ventricular Assist Device: A Systematic Review Original Articles
Conclusions— The totality of data for continuous-flow left ventricular assist devices show consistent improvements in survival and quality of life counterbalanced by a range of common complications. Although this summary should provide a practical resource for healthcare provider-led discussions with patients, it highlights the critical need for high-quality patient-centered data collected with standard definitions.
Source: Circulation: Heart Failure - November 18, 2014 Category: Cardiology Authors: McIlvennan, C. K., Magid, K. H., Ambardekar, A. V., Thompson, J. S., Matlock, D. D., Allen, L. A. Tags: Congestive, CV surgery: transplantation, ventricular assistance, cardiomyopathy Original Articles Source Type: research

Relationship Between Cerebral Blood Flow and Blood Pressure in Long-Term Heart Transplant Recipients Cerebral Blood Flow
Heart transplant recipients are at an increased risk for cerebral hemorrhage and ischemic stroke; yet, the exact mechanism for this derangement remains unclear. We hypothesized that alterations in cerebrovascular regulation is principally involved. To test this hypothesis, we studied cerebral pressure-flow dynamics in 8 clinically stable male heart transplant recipients (62±8 years of age and 9±7 years post transplant, mean±SD), 9 male age-matched controls (63±8 years), and 10 male donor controls (27±5 years). To increase blood pressure variability and improve assessment of the pressure-f...
Source: Hypertension - November 12, 2014 Category: Cardiology Authors: Smirl, J. D., Haykowsky, M. J., Nelson, M. D., Tzeng, Y.-C., Marsden, K. R., Jones, H., Ainslie, P. N. Tags: Doppler ultrasound, Transcranial Doppler etc. Cerebral Blood Flow Source Type: research

Genotype-Positive Status in Patients With Hypertrophic Cardiomyopathy Is Associated With Higher Rates of Heart Failure Events Original Articles
Conclusions— The presence of a pathogenic sarcomere mutation in patients with hypertrophic cardiomyopathy was associated with an increase in heart failure events, with no differences in event rates seen between myosin heavy chain and myosin-binding protein C genotype-positive patients. The presence of a disease-causing mutation seems more clinically relevant than the specific mutation itself.
Source: Circulation: Cardiovascular Genetics - August 19, 2014 Category: Cardiology Authors: Li, Q., Gruner, C., Chan, R. H., Care, M., Siminovitch, K., Williams, L., Woo, A., Rakowski, H. Tags: Other heart failure, Myocardial cardiomyopathy disease, Genetics of cardiovascular disease Original Articles Source Type: research

Slope in preload recruitable stroke work relationship predicts survival after left ventriculoplasty and mitral repair in patients with idiopathic cardiomyopathy.
CONCLUSIONS: Mw, the slope in the PRSW relationship, may predict survival after LVP and MVP in patients with idiopathic DCM. PMID: 24954287 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - June 18, 2014 Category: Cardiology Authors: Shingu Y, Kubota S, Wakasa S, Ooka T, Kato H, Tachibana T, Matsui Y Tags: J Cardiol Source Type: research

Cardiovascular Risk Assessment Before and After Kidney Transplantation
Cardiovascular disease (CVD) is the leading cause of death in dialysis patients and the most common cause of death and allograft loss among kidney transplant recipients. End-stage renal disease (ESRD) is associated with an increased incidence and prevalence of a wide range of CVDs including coronary artery disease, stroke, congestive heart failure, atrial fibrillation, sudden cardiac death, pulmonary hypertension, and valvular heart disease. CVD risk factors are very common in patients with ESRD, and most patients have multiple risk factors. Kidney transplantation is the treatment of choice for patients with ESRD, as a suc...
Source: Cardiology in Review - June 6, 2014 Category: Cardiology Tags: Review Articles Source Type: research

Abstract 271: Anti-coagulation and Ischemic Stroke Risk in Patients with Chronic Kidney Disease and Atrial Fibrillation: Insights from the Kaiser Permanente Colorado Atrial Fibrillation Registry Session Title: Poster Session II
Conclusion: 1 in 3 patients with atrial fibrillation have CKD. There were similar reductions in the risk of stroke associated with warfarin use for CKD and non-CKD patients. These findings reinforce current clinical practice guidelines, which recommend warfarin use based on thromboembolic risk without consideration for CKD status.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Schneider, P. M., Tavel, H. M., Witt, D. M., Kauffman, Y. S., Shetterly, S. M., Go, A. S., Ho, P. M., Magid, D. J. Tags: Session Title: Poster Session II Source Type: research

Abstract 125: Clinical Outcomes Following Continuous-Flow Left Ventricular Assist Device: A Systematic Review Session Title: Poster Session I
Conclusion: The totality of data for CF LVADs show consistent improvements in survival and quality of life counterbalanced by a range of common complications. While this summary should provide a practical resource for health care provider-led discussions with patients, it highlights the critical need for high-quality patient-centered data collected with standard definitions.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: McIlvennan, C. K., Magid, K. H., Ambardekar, A. V., Thompson, J. S., Matlock, D. D., Allen, L. A. Tags: Session Title: Poster Session I Source Type: research

Pre-Operative Risk Factors of Bleeding and Stroke During Left Ventricular Assist Device Support An Analysis of More Than 900 HeartMate II Outpatients
ConclusionsThe risk of bleeding and thrombotic events during LVAD support differs by patient demographics, including sex, age, body mass index, and etiology of heart failure. Further studies should focus on the potential of tailored anticoagulation strategies in these subgroups.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - March 3, 2014 Category: Cardiology Source Type: research

Thrombolytic Therapy for Thrombosis of Continuous Flow Ventricular Assist Devices
Conclusions: In the setting of LVAD thrombosis, thrombolytic therapy is an alternate treatment strategy in a subset of patients. Candidacy for this alternate procedure must carefully weigh the risks of complications, including hemorrhage and thromboembolism.
Source: Journal of Cardiac Failure - December 19, 2013 Category: Cardiology Authors: Kelly Schlendorf, Chetan B. Patel, Thomas Gehrig, Todd L. Kiefer, G. Michael Felker, Adrian F. Hernandez, Laura J. Blue, Carmelo A. Milano, Joseph G. Rogers Tags: Clinical Investigations Source Type: research

Pathomorphologic findings in left ventricular hypertrabeculation/noncompaction of adults in relation to neuromuscular disorders
Conclusion: Formaldehyde-fixation should be performed when comparing ECHO with PATHO findings in LVHT. Long-axis as well as short-axis cuts should be carried out in order to assess the course of trabeculations and the extent of the two-layered structure. Subendocardial fibrosis in LVHT deserves further research.
Source: International Journal of Cardiology - October 31, 2013 Category: Cardiology Authors: Daniel Gerger, Claudia Stöllberger, Martin Grassberger, Birgit Gerecke, Horst Andresen, Rolf Engberding, Josef Finsterer Tags: Original Articles Source Type: research

Anticoagulation with a new oral anticoagulant in heart transplant recipients
Rivaroxaban is now accepted for prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation with one or more risk factors, and treatment and secondary prevention of deep vein thrombosis and pulmonary embolism. Nothing is known about the use of this new anticoagulant in transplanted patients. Here we report a series of heart transplant recipients treated with rivaroxaban and followed at our transplantation center.
Source: International Journal of Cardiology - July 25, 2013 Category: Cardiology Authors: Pierre Ambrosi, Bernard Kreitmann, William Cohen, Gilbert Habib, Pierre Morange Tags: Letters to the Editor Source Type: research

Prognostic Value of N-Terminal Pro-Brain Natriuretic Peptide in Outpatients With Hypertrophic Cardiomyopathy
In hypertrophic cardiomyopathy, the plasma levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) correlate with functional capacity. However, their prognostic relevance remains unresolved. We followed up 183 stable outpatients with hypertrophic cardiomyopathy (age 50 ± 17 years, 64% men) for 3.9 ± 2.8 years after NT-proBNP measurement. The primary end point included cardiovascular death, heart transplantation, resuscitated cardiac arrest, and appropriate implantable cardioverter-defibrillator intervention. The secondary end point (SE) included heart failure-related death or hospitalization, progression to end-...
Source: The American Journal of Cardiology - July 22, 2013 Category: Cardiology Authors: Rossella D'Amato, Benedetta Tomberli, Gabriele Castelli, Roberto Spoladore, Francesca Girolami, Alessandra Fornaro, Anna Caldini, Francesca Torricelli, Paolo Camici, Gian Franco Gensini, Franco Cecchi, Iacopo Olivotto Tags: Cardiomyopathy Source Type: research

Abstract 15: Decisional Needs in Patients Considering Left Ventricular Assist Device as Destination Therapy: Contrast Between Acceptors and Decliners Concurrent Session I Session C: Young Investigator Award Finalists Oral Abstract Presentations
Conclusions: There is a fundamental difference in values surrounding death among patients who either accept or decline a DT LVAD. Decision support interventions around this complex medical decision need to consider patient values first before getting into more cognitive aspects of the decision making process.
Source: Circulation: Cardiovascular Quality and Outcomes - May 15, 2013 Category: Cardiology Authors: McIlvennan, C. K., Allen, L. A., Nowels, C., Cleveland, J. C., Brieke, A., Matlock, D. D. Tags: Concurrent Session I Session C: Young Investigator Award Finalists Oral Abstract Presentations Source Type: research

Chronic renal disease is associated with stroke and thromboembolism in atrial fibrillation independently from gender
We have read with great interest the article by Guo and colleagues concerning renal dysfunction (defined as the presence of chronic dialysis, renal transplantation or an estimated glomerular filtration rate, eGFR,
Source: International Journal of Cardiology - May 3, 2013 Category: Cardiology Authors: Rui Providência, Sérgio Barra, Luís Paiva Tags: Letters to the Editor Source Type: research