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Specialty: Cardiology
Condition: Cholesterol

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Total 2240 results found since Jan 2013.

Low-Density Lipoprotein Cholesterol Is Predominantly Associated With Atherosclerotic Cardiovascular Disease Events in Patients With Evidence of Coronary Atherosclerosis: The Western Denmark Heart Registry
CONCLUSIONS: LDL-C appears to be almost exclusively associated with ASCVD events over ≈5 years of follow-up in middle-aged individuals with versus without evidence of coronary atherosclerosis. This information is valuable for individualized risk assessment among middle-aged people with or without coronary atherosclerosis.PMID:36621817 | DOI:10.1161/CIRCULATIONAHA.122.061010
Source: Circulation - January 9, 2023 Category: Cardiology Authors: Martin B ødtker Mortensen Omar Dzaye Hans Erik B øtker Jesper M øller Jensen Michael Maeng Jacob Fog Bentzen Helle Kanstrup Henrik Toft S ørensen Jonathon Leipsic Ron Blankstein Khurram Nasir Michael J Blaha Bjarne Linde N ørgaard Source Type: research

Air Pollution: Another Threat to HDL Function
Int J Mol Sci. 2022 Dec 24;24(1):317. doi: 10.3390/ijms24010317.ABSTRACTEpidemiological studies have consistently demonstrated a positive association between exposure to air pollutants and the incidence of cardiovascular disease, with the strongest evidence for particles with a diameter < 2.5 μm (PM2.5). Therefore, air pollution has been included among the modifiable risk factor for cardiovascular outcomes as cardiovascular mortality, acute coronary syndrome, stroke, heart failure, and arrhythmias. Interestingly, the adverse effects of air pollution are more pronounced at higher levels of exposure but were also sho...
Source: Atherosclerosis - January 8, 2023 Category: Cardiology Authors: Alice Ossoli Federica Cetti Monica Gomaraschi Source Type: research

Microarray Expression Profile of Myricetin-Treated THP-1 Macrophages Exhibits Alterations in Atherosclerosis-Related Regulator Molecules and LXR/RXR Pathway
Int J Mol Sci. 2022 Dec 23;24(1):278. doi: 10.3390/ijms24010278.ABSTRACTAtherosclerosis is a chronic inflammation characterized by macrophage infiltration, lipid deposition, and arterial wall thickening. Prevention of atherosclerosis by nutraceuticals is gaining attention. Myricetin, a dietary flavonol, is claimed to possess anti-atherosclerosis properties. We studied myricetin's effect on the atherosclerosis-associated molecular mechanism. Cytotoxicity and proliferation testing to check the viability of myricetin-treated THP-1 macrophages and monocyte migration study in the presence and absence of myricetin was performed....
Source: Atherosclerosis - January 8, 2023 Category: Cardiology Authors: Etimad Huwait Rehab Almassabi Sanaa Almowallad Salma Saddeek Sajjad Karim Gauthaman Kalamegam Zeenat Mirza Source Type: research

Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank
Conclusions Individuals hospitalised with COVID-19 have increased risk of incident cardiovascular events across a range of disease and mortality outcomes. The risk of most events is highest in the early postinfection period. Individuals not requiring hospitalisation have increased risk of VTE, but not of other cardiovascular-specific outcomes.
Source: Heart - December 22, 2022 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., Salih, A., Raman, B., Lee, A. M., Neubauer, S., Harvey, N. C., Petersen, S. E. Tags: Open access, Editor's choice, Press releases, COVID-19 Cardiac risk factors and prevention Source Type: research

PrevAleNce and Associated factors of inappropriaTe dosing of direct Oral anticoaguLants In pAtients with Atrial Fibrillation: the ANATOLIA-AF Study
ConclusionThe study demonstrated that the prevalence of inappropriate direct oral anticoagulant dosing according to the European Heart Rhythm Association recommendations was 24.9% in patients with atrial fibrillation. Several demographic and clinical factors were associated with the inappropriate prescription of direct oral anticoagulants.
Source: Cardiovascular Drugs and Therapy - December 17, 2022 Category: Cardiology Source Type: research

Translational Molecular Imaging Tool of Vulnerable Carotid Plaque: Evaluate Effects of Statin Therapy on Plaque Inflammation and American Heart Association-Defined Risk Levels in Cuff-Implanted Apolipoprotein E-Deficient Mice
Transl Stroke Res. 2022 Dec 9. doi: 10.1007/s12975-022-01114-4. Online ahead of print.NO ABSTRACTPMID:36481841 | DOI:10.1007/s12975-022-01114-4
Source: Atherosclerosis - December 9, 2022 Category: Cardiology Authors: Joyce M S Chan Sung-Jin Park Michael Ng Way Cherng Chen Wan Ying Chan Kishore Bhakoo Tze Tec Chong Source Type: research

Statins and Clinical Outcomes in Patients With Low to Moderate Risk but With Non-obstructive Carotid Plaques: The SCOPE-CP Study
CONCLUSIONS: Benefit of statin therapy was likely to be limited in low to moderate risk patients with carotid plaques. These results could guide physicians in clinical decision-making regarding cardiovascular prevention.PMID:36478652 | PMC:PMC9742388 | DOI:10.4070/kcj.2022.0154
Source: Korean Circulation Journal - December 8, 2022 Category: Cardiology Authors: Minjae Yoon Chan Joo Lee Sungha Park Sang-Hak Lee Source Type: research