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Specialty: Cardiology
Condition: Cholesterol

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Total 2240 results found since Jan 2013.

Correspondence to: “Association of remnant cholesterol with risk of cardiovascular disease events, stroke, and mortality: A systemic review and meta-analysis”
We read with great interest the paper by Yang et al. published in Atherosclerosis, reporting that remnant cholesterol (RC) levels are associated with increased risk of adverse cardiovascular events, stroke and mortality [1]. Given the recent advances in hypolipidemic treatments, RC has been brought to the spotlight as a potential prognostic and therapeutic biomarker of residual atherosclerotic cardiovascular disease risk (ASCVD) beyond LDL-C [2,3]. Therefore, these findings are of clinical relevance and support the clinical applicability of RC in this setting.
Source: Atherosclerosis - June 5, 2023 Category: Cardiology Authors: Elpida Athanasopoulou, Athanase D. Protogerou Tags: Correspondence Source Type: research

Blood phytosterols in relation to cardiovascular diseases and mediating effects of blood lipids and hematological traits: a Mendelian randomization analysis
CONCLUSION: The study suggests that genetic predisposition to higher blood total sitosterol is linked to a greater risk of major CVDs. Moreover, blood nonHDL-C and apolipoprotein B might mediate a significant proportion of the associations between sitosterol and coronary diseases.PMID:37270173 | DOI:10.1016/j.metabol.2023.155611
Source: Atherosclerosis - June 3, 2023 Category: Cardiology Authors: Yimin Zhao Zhenhuang Zhuang Yueying Li Wendi Xiao Zimin Song Ninghao Huang Wenxiu Wang Xue Dong Jinzhu Jia Tao Huang Source Type: research

Higher Non-High-Density Lipoprotein Cholesterol Was Higher Associated With Cardiovascular Disease Comparing Higher LDL-C in Nine Years Follow Up: Cohort Study
CONCLUSION: In our large population study, higher non-HDL-C levels were associated with CVD than LDL-C levels.PMID:37265846 | PMC:PMC10232221 | DOI:10.12997/jla.2023.12.2.164
Source: Atherosclerosis - June 2, 2023 Category: Cardiology Authors: Sangmo Hong Kyungdo Han Jung Hwan Park Sung Hoon Yu Chang Beom Lee Dong Sun Kim Source Type: research

Plasma ANGPTL8 Levels and Risk for Secondary Cardiovascular Events in Japanese Patients With Stable Coronary Artery Disease Receiving Statin Therapy
CONCLUSIONS: Monitoring ANGPTL8 levels over time might be useful to assess residual risk of cardiovascular secondary events in patients with cardiovascular disease undergoing statin therapy.PMID:37259862 | DOI:10.1161/ATVBAHA.122.318880
Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 1, 2023 Category: Cardiology Authors: Jun Morinaga Kosuke Kashiwabara Daisuke Torigoe Yusuke Okadome Kenichi Aizawa Kohei Uemura Ai Kurashima Eiji Matsunaga Hirotaka Fukami Haruki Horiguchi Michio Sato Taichi Sugizaki Keishi Miyata Tsuyoshi Kadomatsu Masashi Mukoyama Katsumi Miyauchi Seiji Ho Source Type: research

Trends in low-density lipoprotein cholesterol goal achievement and changes in lipid-lowering therapy after incident atherosclerotic cardiovascular disease: Danish cohort study
CONCLUSION: LDL-C goal achievement within the first 2 years after inclusion increased from 40.5% in 2010 to 50.6% in 2015. LLT initiation within the first year after inclusion increased, especially for intensive LLT, although only one third initiated intensive LLT in 2015. Despite trends show improvements in LDL-C goal achievement, 49.4% of individuals at very high risk of a CV event did not achieve the LDL-C goal within 2 years after ASCVD hospitalization.PMID:37256879 | PMC:PMC10231813 | DOI:10.1371/journal.pone.0286376
Source: Atherosclerosis - May 31, 2023 Category: Cardiology Authors: Annette Kj ær Ersbøll Marie Skov Kristensen Mads Nybo Simone M øller Hede Kristian Handberg Mikkelsen Gunnar Gislason Mogens Lytken Larsen Anders Green Source Type: research

Associations of plaque morphology and location with Intraplaque neovascularization in the carotid artery by contrast-enhanced ultrasound imaging
CONCLUSION: The location and morphology of carotid plaques were significantly associated with the IPN grade on CEUS, and therefore show potential as biomarkers for plaque vulnerability. Serum HDL-C was also identified as a protective factor against IPN, and may play a role in the management of carotid atherosclerosis. Our study provided a potential strategy for identification of vulnerable carotid plaques and elucidated the important imaging predictors of stroke.PMID:37251224 | PMC:PMC10213664 | DOI:10.3389/fneur.2023.1097070
Source: Atherosclerosis - May 30, 2023 Category: Cardiology Authors: Shi-Yao Gu Lu-Ni Zhang Jing Chen Fang Li Ming-Hua Yao Cai-Xia Jia Rong Wu Source Type: research

Development and validation of explainable machine-learning models for carotid atherosclerosis early screening
CONCLUSIONS: The ML models developed could provide good performance for CAS identification using routine health check-up indicators and could hopefully be applied in scenarios without ethnic and geographic heterogeneity for CAS prevention.PMID:37246225 | DOI:10.1186/s12967-023-04093-8
Source: Atherosclerosis - May 28, 2023 Category: Cardiology Authors: Ke Yun Tao He Shi Zhen Meihui Quan Xiaotao Yang Dongliang Man Shuang Zhang Wei Wang Xiaoxu Han Source Type: research