Stroke RSS Page 16

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Specialty: Cardiology
Condition: Cholesterol

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Total 2240 results found since Jan 2013.

Population-wide cohort study of statin use for the secondary cardiovascular disease prevention in Scotland in 2009-2017
Conclusions Statin use remains suboptimal for the secondary ASCVD prevention, particularly in women and older patients, and following ischaemic stroke and PAD hospitalisations. Improving this would offer substantial benefits to population health at low cost.
Source: Heart - February 14, 2023 Category: Cardiology Authors: Thalmann, I., Preiss, D., Schlackow, I., Gray, A., Mihaylova, B. Tags: Open access Healthcare delivery, economics and global health Source Type: research

Association Between Achieved Low-Density Lipoprotein Cholesterol Levels and Long-Term Cardiovascular and Safety Outcomes: An Analysis of FOURIER-OLE
CONCLUSIONS: In patients with atherosclerotic cardiovascular disease, long-term achievement of lower LDL-C levels, down to <20 mg/dL (<0.5 mmol/L), was associated with a lower risk of cardiovascular outcomes with no significant safety concerns.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT01764633.PMID:36779348 | DOI:10.1161/CIRCULATIONAHA.122.063399
Source: Atherosclerosis - February 13, 2023 Category: Cardiology Authors: Prakriti Gaba Michelle L O'Donoghue Jeong-Gun Park Stephen D Wiviott Dan Atar Julia F Kuder KyungAh Im Sabina A Murphy Gaetano M De Ferrari Zbigniew A Gaciong Kalman Toth Ioanna Gouni-Berthold Jose Lopez-Miranda Fran çois Schiele Fran çois Mach Jose H F Source Type: research

Carotid atherosclerosis in people of European, South Asian and African Caribbean ethnicity in the Southall and Brent revisited study (SABRE)
CONCLUSION: Prevalence of carotid artery atherosclerotic plaques varies by ethnicity, independent of risk factors. Lower plaque prevalence in in AC is consistent with their lower risk of CHD but not their higher risk of stroke. Higher cIMT in AC may be explained by risk factors. The similarity of plaque burden in SA and EA despite established differences in ASCVD risk casts some doubt on the utility of carotid ultrasound as a means of assessing risk across these ethnic groups.PMID:36762303 | PMC:PMC9902363 | DOI:10.3389/fcvm.2022.1002820
Source: Atherosclerosis - February 10, 2023 Category: Cardiology Authors: Rayan Anbar Nish Chaturvedi Sophie V Eastwood Therese Tillin Alun D Hughes Source Type: research

Benefit of Combination Ezetimibe/Simvastatin Among High-Risk Populations: Lessons from the IMPROVE-IT Trial
AbstractPurpose of ReviewThe Improved Reduction of Outcomes: Vytorin Efficacy International Trial (IMPROVE-IT) demonstrated the clinical benefit of the combination of ezetimibe-simvastatin compared to placebo-simvastatin following acute coronary syndrome (ACS). This review highlights key findings from this study with particular attention to the practice-changing impact on guidelines for low-density lipoprotein cholesterol (LDL-C) reduction after ACS, especially among high-risk populations.Recent FindingsConsistent reductions in LDL-C have been reported with newer lipid-lowering therapies (proprotein convertase subtilisin/k...
Source: Current Atherosclerosis Reports - February 10, 2023 Category: Cardiology Source Type: research

Novel biomarkers and emerging tools to identify causal molecular pathways in hypertension and associated cardiovascular diseases
Kardiol Pol. 2023 Feb 5. doi: 10.33963/KP.a2023.0037. Online ahead of print.ABSTRACTHypertension (HT) is a modifiable risk factor for life-threatening cardiovascular diseases (CVDs) including coronary artery disease, heart failure or stroke. Despite significant progress in understanding of the pathophysiological mechanisms of the disease, the molecular pathways targeted by HT treatment still remain largely unchanged. This warrants the necessity for searching novel biomarkers, which are causally related to persistent high blood pressure (BP) and may be pharmacologically targeted. Data from large-scale biobanks, containing h...
Source: Polish Heart Journal - February 5, 2023 Category: Cardiology Authors: Ewelina J ózefczuk Tomasz J Guzik Mateusz Siedlinski Source Type: research

Association between Low-Density Lipoprotein Cholesterol Level and Cardiovascular Outcomes in Korean Adults: A Nationwide Cohort Study
CONCLUSION: We confirmed the incidence of CVD was increased in higher LDL-C range. The risk of CVD increased from ≥70 mg/dL of LDL-C in very high-risk and high-risk groups, and from ≥130 mg/dL of LDL-C in moderate-risk and low-risk groups in Korean adults.PMID:36727164 | DOI:10.4093/dmj.2021.0320
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Junghyun Noh Min Kyong Moon Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

Cardiovascular Outcomes according to Comorbidities and Low-Density Lipoprotein Cholesterol in Korean People with Type 2 Diabetes Mellitus
CONCLUSION: For primary prevention of CVD in Korean adults with T2DM, it can be helpful to lower LDL-C targets when there are chronic kidney disease, HT, a long duration of diabetes mellitus, or three or more CV risk factors.PMID:36727163 | DOI:10.4093/dmj.2021.0344
Source: Atherosclerosis - February 2, 2023 Category: Cardiology Authors: Min Kyong Moon Junghyun Noh Eun-Jung Rhee Sang Hyun Park Hyeon Chang Kim Byung Jin Kim Hae Jin Kim Seonghoon Choi Jin Oh Na Young Youl Hyun Bum Joon Kim Kyung-Do Han In-Kyung Jeong Source Type: research

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