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Specialty: Cardiology
Condition: Cholesterol
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Total 2240 results found since Jan 2013.
Statins influence the relationship between ATP-binding cassette A1 membrane transporter-mediated cholesterol efflux capacity and coronary atherosclerosis in rheumatoid arthritis
CONCLUSION: In patients with RA, higher ABCA1-CEC may reflect a proatherogenic state, associated with enhanced cardiovascular risk. Statin use may unmask the protective impact of ABCA1-mediated cholesterol efflux on plaque formation, progression and cardiovascular risk.PMID:37484708 | PMC:PMC10362327 | DOI:10.1016/j.jtauto.2023.100206
Source: Atherosclerosis - July 24, 2023 Category: Cardiology Authors: George A Karpouzas Bianca Papotti Sarah R Ormseth Marcella Palumbo Elizabeth Hernandez Maria Pia Adorni Francesca Zimetti Matthew J Budoff Nicoletta Ronda Source Type: research
Residual Coronary Risk Factors Associated With Long-Term Clinical Outcomes in Patients With Coronary Artery Disease Treated With High- vs. Low-Dose Statin Therapy - REAL-CAD Substudy
CONCLUSIONS: Regarding nonlipid prognostic factors contributing to the incidence of cardiovascular events in statin-treated CAD patients, renal dysfunction was the most significant, followed by poor glucose control and high SBP.PMID:37482412 | DOI:10.1253/circj.CJ-23-0134
Source: Circulation Journal - July 23, 2023 Category: Cardiology Authors: Takumi Higuma Yoshihiro J Akashi Yoshihiro Fukumoto Hitoshi Obara Tatsuyuki Kakuma Yasuhide Asaumi Satoshi Yasuda Ichiro Sakuma Hiroyuki Daida Hiroaki Shimokawa Takeshi Kimura Satoshi Iimuro Ryozo Nagai Source Type: research
Rate of Change in 10-Year Atherosclerotic Cardiovascular Disease Risk and Its Implications for Primary Prevention
CONCLUSIONS: The temporal change in 10-year ASCVD risk over a period of 4 to 5 years reflects success or failure in controlling major cardiovascular risk factors and indicates the risk of future ASCVD events. The ∆10-year ASCVD risk/year can be used as an indicator of primary prevention and guide the application of preventive measures.PMID:37470768 | DOI:10.1161/HYPERTENSIONAHA.122.20678
Source: Atherosclerosis - July 20, 2023 Category: Cardiology Authors: In-Chang Hwang Chee Hae Kim Jae-Young Kim Hong-Mi Choi Yeonyee E Yoon Goo-Yeong Cho Source Type: research
Independent Causal Effect of Remnant Cholesterol on Atherosclerotic Cardiovascular Outcomes: A Mendelian Randomization Study
CONCLUSIONS: This large-scale Mendelian randomization study showed a robust genetic causal association between RC and cardiovascular outcomes. The effect on CAD and MI is independent of LDL cholesterol. Early screening for RC along with long-term inhibition of RC should be the focus of future therapeutic interventions.PMID:37439258 | DOI:10.1161/ATVBAHA.123.319297
Source: Arteriosclerosis, Thrombosis and Vascular Biology - July 13, 2023 Category: Cardiology Authors: Eliano P Navarese Donna Vine Spencer Proctor Klaudyna Grzelakowska Sergio Berti Jacek Kubica Paolo Raggi Source Type: research
Atherosclerosis on CT coronary angiography and risk of long-term cardiovascular events post liver transplantation
CONCLUSION: The standardized CAD-RADS classification on CTCA predicted the occurrence of cardiovascular outcomes following LT, with a potential to increase utilization of preventive cardiovascular therapies.PMID:37432891 | DOI:10.1097/LVT.0000000000000215
Source: Atherosclerosis - July 11, 2023 Category: Cardiology Authors: Thalys Sampaio Rodrigues Anoop N Koshy Paul J Gow Laurence Weinberg Benjamin Cailes Adam Testro Gerard Smith Han S Lim Andrew W Teh Ruth P Lim Omar Farouque Source Type: research
Evidence of an anti-inflammatory effect of PCSK9 inhibitors within the human atherosclerotic plaque
CONCLUSIONS: The use of PCSK9 inhibitors is accompanied by a beneficial remodelling of the inflammatory burden within the human atheroma, an effect possibly or partly independent of their LDL-C lowering ability. This phenomenon might provide an additional cardiovascular benefit.PMID:37422356 | DOI:10.1016/j.atherosclerosis.2023.06.971
Source: Atherosclerosis - July 8, 2023 Category: Cardiology Authors: Raffaele Marfella Francesco Prattichizzo Celestino Sardu Pasquale Paolisso Nunzia D'Onofrio Lucia Scisciola Rosalba La Grotta Chiara Frig é Franca Ferraraccio Iacopo Panarese Mara Fanelli Piero Modugno Antonio Maria Calafiore Mario Melchionna Ferdinando Source Type: research
Effects of adjuvant berberine therapy on acute ischemic stroke: A meta-analysis
Phytother Res. 2023 Jul 8. doi: 10.1002/ptr.7920. Online ahead of print.ABSTRACTWe conducted a meta-analysis to evaluate the clinical efficacy of berberine (BBR) in treating acute ischemic stroke (AIS), explore its anti-inflammatory effects, and assess its potential applications for AIS patients. We comprehensively searched nine databases from inception until July 1, 2022, to identify clinical trials investigating the use of BBR in treating AIS. We performed statistical analyses using RevMan5.4 software and focused on primary outcomes such as inflammatory markers as well as secondary outcomes including immune system indica...
Source: Atherosclerosis - July 8, 2023 Category: Cardiology Authors: Dan Luo Baili Yu Shoukai Sun Bonan Chen Harsh Vivek Harkare Longlong Wang Jie Pan Bin Huang Yang Song Tianhong Ma Shihua Shi Source Type: research
Associations of Tissue and Soluble LOX-1 with Human Abdominal Aortic Aneurysm
Conclusions In AAA, sLOX-1 was differently affected by age, cardiometabolic diseases, and corresponding medical therapies. Comparison with nonatherosclerotic disease would be beneficial to further elucidate the diagnostic potential of sLOX-1, although it was not useful for risk stratification. Aneurysmal LOX-1 mRNA expression was increased and positively associated with smooth muscle cells and collagen content, suggesting that LOX-1 is eventually not deleterious in human AAA and could counteract AAA rupture.PMID:37421287 | DOI:10.1161/JAHA.122.027537
Source: Atherosclerosis - July 8, 2023 Category: Cardiology Authors: Anja Hofmann Yazan Khorzom Anna Klimova Steffen Wolk Albert Busch Pamela Sabarstinski Margarete M üglich Dmitry Egorov Irakli Kopaliani David M Poitz Marvin Kapalla Bianca Hamann Frieda Frank Christian J änichen Coy Brunssen Henning Morawietz Christian Source Type: research
