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Specialty: Cardiology
Condition: Cholesterol

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Total 2240 results found since Jan 2013.

Gender differences in cardiovascular risk, treatment, and outcomes: a post hoc analysis from the REWIND trial
Conclusions. In REWIND, most women met clinically relevant treatment targets, but in lower proportions than men. Women had a lower risk for all cardiovascular outcomes except stroke. Clinical trials.gov registration number: NCT01394952.PMID:36723445 | DOI:10.1080/14017431.2023.2166101
Source: Scandinavian Cardiovascular Journal - February 1, 2023 Category: Cardiology Authors: Giulia Ferrannini Juan M Maldonado Sohini Raha Purnima Rao-Melacini Rutaba Khatun Charles Atisso Linda Shurzinske Hertzel C Gerstein Lars Ryd én M Angelyn Bethel Source Type: research

A Non-Linear Role of Hyperlipidemia on Progression of Intracranial Atherosclerotic Plaques and Acute Downstream Ischemic Events
CONCLUSIONS: LDL was related with ischemia events in intermediate stage of intracranial atherosclerotic plaque progression, an excellent period for intensive lipid-lowering treatment. In advanced stage, inflammatory agents maybe the main contributor to ischemic events.PMID:36709996 | DOI:10.5551/jat.63971
Source: Journal of Atherosclerosis and Thrombosis - January 29, 2023 Category: Cardiology Authors: Jianxia Ke Jinrui Li Junting Chen Chengze Lai Weicheng Zheng Xiaoli Fu Xuewen Fang Lianxian Guo Zhu Shi Source Type: research

Rationale and design of a randomised double-blind 2 ×2 factorial trial comparing the effect of a 3-month intensive statin and antiplatelet therapy for patients with acute mild ischaemic stroke or high-risk TIA with intracranial or extracranial atherosclerosis (INSPIRES)
CONCLUSION: The INSPIRES trial will assess the efficacy and safety of intensive antiplatelet therapy and immediate intensive statin therapy begun within 72 hours of onset in decreasing the recurrent stroke at 90 days in patients with acute mild ischaemic stroke or high-risk TIA of intracranial or extracranial atherosclerosis origin.TRIAL REGISTRATION NUMBER: NCT03635749.PMID:36707080 | DOI:10.1136/svn-2022-002084
Source: Atherosclerosis - January 27, 2023 Category: Cardiology Authors: Ying Gao Yuesong Pan Shangrong Han Weiqi Chen Jing Jing Chunjuan Wang Yingying Yang Tingting Wang Xia Meng Xingquan Zhao Liping Liu Hao Li S Claiborne Johnston Pierre Amarenco Philip M Bath Yongjun Wang Yilong Wang INSPIRES Investigators Source Type: research

Heart Disease and Stroke Statistics-2023 Update: A Report From the American Heart Association
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.PMID:36695182 | DOI:10.1161/CIR.0000000000001123
Source: Circulation - January 25, 2023 Category: Cardiology Authors: Connie W Tsao Aaron W Aday Zaid I Almarzooq Cheryl A M Anderson Pankaj Arora Christy L Avery Carissa M Baker-Smith Andrea Z Beaton Amelia K Boehme Alfred E Buxton Yvonne Commodore-Mensah Mitchell S V Elkind Kelly R Evenson Chete Eze-Nliam Setri Fugar Giul Source Type: research

Prognostic Implication of Small Dense LDL-Cholesterol Levels following Acute Coronary Syndrome
Conclusions: Small dense LDL-cholesterol level was a significant risk factor for cardiovascular events following presentations of acute coronary syndrome.PMID:36676782 | DOI:10.3390/medicina59010158
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Teruhiko Imamura Masakazu Hori Nikhil Narang Hiroshi Ueno Koichiro Kinugawa Source Type: research

Low-Density Lipoprotein Cholesterol Is Predominantly Associated With Atherosclerotic Cardiovascular Disease Events in Patients With Evidence of Coronary Atherosclerosis: The Western Denmark Heart Registry
CONCLUSIONS: LDL-C appears to be almost exclusively associated with ASCVD events over ≈5 years of follow-up in middle-aged individuals with versus without evidence of coronary atherosclerosis. This information is valuable for individualized risk assessment among middle-aged people with or without coronary atherosclerosis.PMID:36621817 | DOI:10.1161/CIRCULATIONAHA.122.061010
Source: Circulation - January 9, 2023 Category: Cardiology Authors: Martin B ødtker Mortensen Omar Dzaye Hans Erik B øtker Jesper M øller Jensen Michael Maeng Jacob Fog Bentzen Helle Kanstrup Henrik Toft S ørensen Jonathon Leipsic Ron Blankstein Khurram Nasir Michael J Blaha Bjarne Linde N ørgaard Source Type: research

SARS-CoV-2 infection and SLE: endothelial dysfunction, atherosclerosis, and thrombosis
We present systemic lupus erythematosus (SLE) as a model rheumatic disease with endothelial dysfunction and discuss its mechanisms, factors that influence the early onset and rapid progression of atherosclerosis, and the increased risk of thromboembolic events. We focus on established methods to improve endothelium function, including statins, antiplatelet, and antithrombotic therapy. Hypercoagulable and hypofibrinolitic states and a hyperinflammatory response characterize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Several pathogenic mechanisms are typical for an acute phase of Covid-19 post-Co...
Source: Atherosclerosis - January 9, 2023 Category: Cardiology Authors: Wojciech P łazak Leszek Drabik Source Type: research

Low-Density Lipoprotein Cholesterol Is Predominantly Associated With Atherosclerotic Cardiovascular Disease Events in Patients With Evidence of Coronary Atherosclerosis: The Western Denmark Heart Registry
CONCLUSIONS: LDL-C appears to be almost exclusively associated with ASCVD events over ≈5 years of follow-up in middle-aged individuals with versus without evidence of coronary atherosclerosis. This information is valuable for individualized risk assessment among middle-aged people with or without coronary atherosclerosis.PMID:36621817 | DOI:10.1161/CIRCULATIONAHA.122.061010
Source: Atherosclerosis - January 9, 2023 Category: Cardiology Authors: Martin B ødtker Mortensen Omar Dzaye Hans Erik B øtker Jesper M øller Jensen Michael Maeng Jacob Fog Bentzen Helle Kanstrup Henrik Toft S ørensen Jonathon Leipsic Ron Blankstein Khurram Nasir Michael J Blaha Bjarne Linde N ørgaard Source Type: research