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Total 468 results found since Jan 2013.

Is Arterial Stiffness a Determinant of Hypotension?
ConclusionsHypotension is a quite common phenomenon in older subjects. Its prevention requires a more accurate management of hypertension aimed at better identifying which older subjects in whom intensive BP control may be harmful and those who may benefit from it.
Source: High Blood Pressure and Cardiovascular Prevention - May 7, 2020 Category: Cardiology Source Type: research

Sodium Handling and Interaction in Numerous Organs.
Abstract Salt (NaCl) is a prerequisite for life. Excessive intake of salt, however, is said to increase disease risk including hypertension, arteriosclerosis, heart failure, renal disease, stroke, and cancer. Therefore, considerable research has been expended on the mechanism of sodium handling based on the current concepts of sodium balance. The studies have necessarily relied on relatively short-term experiments and focused on extremes of salt intake in humans. Ultra-long-term salt balance has received far less attention. We performed long-term salt balance studies at intakes of 6, 9, and 12 g/day and found that...
Source: American Journal of Hypertension - March 20, 2020 Category: Cardiology Authors: Minegishi S, Luft FC, Titze J, Kitada K Tags: Am J Hypertens Source Type: research

Frequency of Seaweed Intake and Its Association with Cardiovascular Disease Mortality: The JACC Study.
CONCLUSIONS: We found an inverse association between seaweed intake and cardiovascular mortality among Japanese men and women, especially that from cerebral infarction. PMID: 32132341 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - March 6, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Effects of glucagon-like peptide-1 receptor agonists on major cardiovascular events in patients with Type 2 diabetes mellitus with or without established cardiovascular disease: a meta-analysis of randomized controlled trials
Conclusion  Glucagon-like peptide-1 receptor agonists significantly reduce MACE, CV and total mortality stroke, and hospitalization for HF, with a trend for reduction of MI, in patients with Type 2 DM with and without established CVD.
Source: European Heart Journal - February 20, 2020 Category: Cardiology Source Type: research

Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study.
CONCLUSIONS: In this population-based study, aromatase inhibitors were associated with increased risks of heart failure and cardiovascular mortality compared with tamoxifen. There were also trends toward increased risks, although nonsignificant, of myocardial infarction and ischemic stroke. The increased risk of cardiovascular events associated with aromatase inhibitors should be balanced with their favorable clinical benefits compared with tamoxifen. PMID: 32065766 [PubMed - in process]
Source: Circulation - February 17, 2020 Category: Cardiology Authors: Khosrow-Khavar F, Filion KB, Bouganim N, Suissa S, Azoulay L Tags: Circulation Source Type: research

Trends in nutritional intake and coronary risk factors over 60  years among Japanese men in Tanushimaru
AbstractWe investigated the relationship between time trends in nutrient intake and coronary risk factors/mortality rates in Tanushimaru, a Japanese cohort of the Seven Countries Study. All men between the ages of 40 and 64 were enrolled. Subjects numbered 628 in 1958, 539 in 1977, 602 in 1982, 752 in 1989, 402 in 1999, 329 in 2009, and 160 in 2018. Eating patterns were evaluated by 24-h dietary recall from 1958 through 1989, and by a food frequency questionnaire administered from 1999 through 2018. The total daily energy intake decreased from 2,837  kcal in 1958 to 2,096 kcal in 2018. Carbohydrate intake as a percentage...
Source: Heart and Vessels - January 28, 2020 Category: Cardiology Source Type: research

Diagnostic strategy of pulmonary embolism in the cardiology department of Ibn Rochd University hospital, Casablanca, Morocco
ConclusionManagement of pulmonary embolism in our cardiology department is characterized by the frequent use of non-invasive techniques on the diagnostic view and appeal to heparin on the therapeutic view.
Source: Archives of Cardiovascular Diseases Supplements - January 7, 2020 Category: Cardiology Source Type: research

Mid-term valve stability after valve sparing aortic root replacement: Outcomes in bicuspid aortic valve compared with tricuspid aortic valve
ConclusionVSRR ensures excellent mid-term aortic valve function independently of its morphology. In B associated with aortic root aneurysm, leaflet repair does not increase the valve-related events.
Source: Archives of Cardiovascular Diseases Supplements - January 7, 2020 Category: Cardiology Source Type: research

Vitamin D, Marine n-3 Fatty Acids, and Primary Prevention of Cardiovascular Disease Current Evidence.
Abstract Whether marine omega-3 fatty acid (n-3 FA) or vitamin D supplementation can prevent cardiovascular disease (CVD) in general populations at usual risk for this outcome is unknown. A major goal of VITAL (Vitamin D and Omega-3 Trial) was to fill this knowledge gap. In this article, we review the results of VITAL, discuss relevant mechanistic studies regarding n-3 FAs, vitamin D, and vascular disease, and summarize recent meta-analyses of the randomized trial evidence on these agents. VITAL was a nationwide, randomized, placebo-controlled, 2×2 factorial trial of marine n-3 FAs (1 g/d) and vitamin D3 (2000 IU...
Source: Circulation Research - January 2, 2020 Category: Cardiology Authors: Manson JE, Bassuk SS, Cook NR, Lee IM, Mora S, Albert CM, Buring JE, VITAL Research Group Tags: Circ Res Source Type: research

Causal Associations Between Serum Bilirubin Levels and Decreased Stroke Risk: A Two-Sample Mendelian Randomization Study.
CONCLUSIONS: Our findings provide evidence of significant causal relationship between high levels of bilirubin and decreased stroke risk in Korean population in agreement with observational approaches. This highlights the potential for bilirubin to serve as a therapeutic target for oxidative stress-related diseases such as stroke and suggests that previous findings were not a consequence of unmeasured confounding. PMID: 31801373 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - December 4, 2019 Category: Cardiology Authors: Choi Y, Lee SJ, Spiller W, Jung KJ, Lee JY, Kimm H, Back JH, Lee S, Jee SH Tags: Arterioscler Thromb Vasc Biol Source Type: research

Orthostatic hypotension and cardiovascular risk.
Abstract Orthostatic hypotension (OH) is a cardinal sign of cardiovascular (CV) autonomic dysfunction as a result of autonomic nervous system failure to control the postural hemodynamic homeostasis. The proportion of individuals with OH increases with aging and chronic conditions, such as neurodegenerative diseases, hypertension, heart failure, diabetes, renal dysfunction, autoimmune diseases and cancer. In those over 70 years, more than 20% can be affected. It is now increasingly recognized that a direct relationship exists between OH and each step of the CV disease continuum, eventually leading to end-stage hear...
Source: Polish Heart Journal - November 7, 2019 Category: Cardiology Authors: Fedorowski A, Ricci F, Sutton R Tags: Kardiol Pol Source Type: research

Treatment of hypertension in old patients without previous cardiovascular disease
Conclusion: Blood pressure levels lower than those currently recommended are not harmful among older patients. The association between lower SBP and lesser risk of CVD may instead suggest a beneficial effect of lower SBP.
Source: Journal of Hypertension - September 30, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

AHA News: Unique Gene Activity Discovered in People With Both Stroke and Cancer
Title: AHA News: Unique Gene Activity Discovered in People With Both Stroke and CancerCategory: Health NewsCreated: 9/12/2019 12:00:00 AMLast Editorial Review: 9/13/2019 12:00:00 AM
Source: MedicineNet Heart General - September 13, 2019 Category: Cardiology Source Type: news

Efficacy and safety of oral anticoagulants in atrial fibrillation patients with cancer —a network meta-analysis
AbstractThere are no guideline recommendations for the use of anticoagulant therapy in atrial fibrillation (AF) patients with cancer, which creates uncertainty about the optimal antithrombotic treatment in these patients. We conducted a network meta-analysis for the first time to assess the efficacy and safety of anticoagulant drugs in patients with AF and concurrent cancer. The PubMed, EMBASE, and Cochrane databases were searched up to March 2019. A search was made for the main anticoagulant drugs (warfarin, dabigatran, apixaban, rivaroxaban, and edoxaban). Outputs were presented as odds ratios (ORs), their corresponding ...
Source: Heart Failure Reviews - August 12, 2019 Category: Cardiology Source Type: research

Atrial fibrillation in active cancer patients: expert position paper and recommendations
Publication date: Available online 9 August 2019Source: Revista Española de Cardiología (English Edition)Author(s): Teresa López-Fernández, Ana Martín-García, Inmaculada Roldán Rabadán, Cristina Mitroi, Pilar Mazón Ramos, Pablo Díez-Villanueva, Carlos Escobar Cervantes, Concepción Alonso Martín, Gonzalo Luis Alonso Salinas, Meritxell Arenas, Vicente Ignacio Arrarte Esteban, Francisco Ayala de La Peña, Antonio Castro Fernández, Héctor García Pardo, Ramón García-Sanz, José Ramón González Porras, Esteban López de Sá, Teresa Lozano, Pascual Marco Vera, Virginia Martínez MarínAbstractImprovements in sur...
Source: Revista Espanola de Cardiologia - August 10, 2019 Category: Cardiology Source Type: research