Evaluation of Cardiovascular Risk in Patient with Primary Non-alcoholic Fatty Liver Disease
ConclusionsSome of the methods for the estimation of cardiovascular risk (ACC/AHA ASCVD 2013, new model 2 2018, and, also Framingham score 2008) have a clear advantage over Framingham score 2004 and “Progetto Cuore” of the Italian Institute of Health in terms of correlation with the severity of NAFLD. They are, therefore, more clinically useful. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - May 20, 2020 Category: Cardiology Source Type: research

Is Arterial Stiffness a Determinant of Hypotension?
AbstractIntroductionPrevious observation identified both hypotension and arterial aging, indexed as Pulse Wave Velocity (PWV), as significant determinants of cognitive decline in older subjects.AimTo investigate the role of PWV as a determinant of hypotension in older patients.MethodsA cohort of 344 subjects came to our Outpatient Clinic, free of cancer, acute myocardial infarction or stroke, atrial fibrillation, renal, hepatic or cardiac failure, secondary hypertension, or thyroid disease.ResultsHypotension occurred in 49% of participants. SBP levels (OR 0.79, 95% CI 0.67 –0.84, p 
Source: High Blood Pressure and Cardiovascular Prevention - May 8, 2020 Category: Cardiology Source Type: research

Multidisciplinary Consensus Document on the Management of Uncontrolled Hypertension in India
AbstractCardiovascular disease is predicted to be the largest cause of death and disability in India by 2020. Hypertension (HT), one of the main contributing factors, presents a significant public health burden. Inability to achieve adequate blood pressure (BP) control results in uncontrolled hypertension (UHT). The prevalence of UHT is high in India, with only about 9 –20% of patients achieving target BP goals. Presently, there are no guidelines specific to UHT, which if left uncontrolled can lead to resistant HT, chronic kidney disease and other complications of HT. A multidisciplinary panel, comprising of speciali...
Source: High Blood Pressure and Cardiovascular Prevention - May 7, 2020 Category: Cardiology Source Type: research

Commentary on “Functional Improvement After Outpatient Cardiac Rehabilitation in Acute Coronary Syndrome Patients is not Related to Improvement in Left Ventricular Ejection Fraction”
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - May 7, 2020 Category: Cardiology Source Type: research

Maurizio Galderisi. In Memoriam
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - May 4, 2020 Category: Cardiology Source Type: research

Epidemiological Impact and Clinical Consequences of Masked Hypertension: A Narrative Review
AbstractMasked hypertension (MHT) is a clinical condition characterized by normal blood pressure (BP) levels during clinical consultation and above normal out-of-office BP values. MHT is associated to an increased risk of developing hypertension-mediated organ damage (HMOD) and major cardiovascular (CV) outcomes, such as myocardial infarction, stroke, and hospitalizations due to CV causes, as well as to metabolic abnormalities and diabetes, thus further promoting the development and progression of atherosclerotic disease. Previous studies showed contrasting data on prevalence and clinical impact of MHT, due to not uniform ...
Source: High Blood Pressure and Cardiovascular Prevention - May 2, 2020 Category: Cardiology Source Type: research

Clinical Use of Impedance Cardiography for Hemodynamic Assessment of Early Cardiovascular Disease and Management of Hypertension
This article is for clinicians considering impedance cardiography (ICG) for secondary prevention. ICG is an inexpensive noninvasive technology that can be used to assess hemodynamic function of the central cardiovascular system. Diverse abnormalities of ventricular function, systolic and diastolic, can be detected by ICG. Additional data pertaining to decompensation can be obtained by taking ICG readings with the patient performing postural change, from upright to supine, to quantify the compensatory response. Vascular load consists of resistive and pulsatile loads. Systemic vascular resistance can provide a measure of res...
Source: High Blood Pressure and Cardiovascular Prevention - April 28, 2020 Category: Cardiology Source Type: research

Renal Denervation in Daily Practice: If So, How?
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - April 23, 2020 Category: Cardiology Source Type: research

Renin-Angiotensin System Inhibition in Cardiovascular Patients at the Time of COVID19: Much Ado for Nothing? A Statement of Activity from the Directors of the Board and the Scientific Directors of the Italian Society of Hypertension
AbstractCardiovascular diseases, in particular hypertension, as well as the cardiovascular treatment with Renin –Angiotensin System inhibitors such as Angiotensin Converting Enzyme (ACE) inhibitors and Angiotensin Receptor Blockers (ARBs), are claimed once again as mechanisms of Severe Acute Respiratory Syndrome (SARS) during the COVID-19 outbreak due to Cov-2 epidemics. In vitro studies are available to su pport the eventual role of ACE inhibitors and ARBs in both the promotion and antagonism of the disease. The available literature, indeed, presents contrasting results, all concentrated in experimental models. Evid...
Source: High Blood Pressure and Cardiovascular Prevention - April 7, 2020 Category: Cardiology Source Type: research

Cardio-Protective Effects of Germinated Brown Rice Extract Against Myocardial Ischemia Reperfusion Injury
ConclusionsThese results suggest that intake of germinated brown rice may effectively to protect cell proliferation and apoptosis and may provide important nutrients to prevent heart failure due to myocardial ischemia. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - April 7, 2020 Category: Cardiology Source Type: research

Elevated Blood Pressure and Associations with Sodium Intake Among Multiethnic Youth in Edmonton, Canada: Findings from WHY ACT NOW
ConclusionsThe prevalence of HT varied by ethnicity. High dietary sodium intake was of concern. There is a need for culturally-tailored, population-based interventions to reduce sodium intake. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - April 7, 2020 Category: Cardiology Source Type: research

Comparing the Attention Score Between American and European Cardiology Guidelines
In this study, we aim to compare the attention brought up by ACC and ESC guidelines.MethodsGuideline documents were defined as documents published by either the ACC or the ESC, where recommendations with a specific level of evidence are clearly indicated. These documents were posted on their respective websites. For each document, we extracted the attention on blogs, news, social media, and other platforms to calculate a total score known as the Altmetric Attention Score (AAS). Then we compared AAS, citations, and other indices between ACC and ESC guideline documents.ResultsA total of 26 US and 24 European cardiology guide...
Source: High Blood Pressure and Cardiovascular Prevention - April 6, 2020 Category: Cardiology Source Type: research

Correction to: Prevalence and Risk Factors of Hypertension in the Vietnamese Elderly
The author affiliations for Deepak B. Thimiri Govinda Raj which previously read. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - March 30, 2020 Category: Cardiology Source Type: research

Single Pill Regimen Leads to Better Adherence and Clinical Outcome in Daily Practice in Patients Suffering from Hypertension and/or Dyslipidemia: Results of a Meta-Analysis
AbstractIntroductionCardiovascular diseases (CVD) represent the first cause of mortality in western countries. Hypertension and dyslipidemia are strong risk factors for CVD, and are prevalent either alone or in combination. Although effective substances for the treatment of both factors are available, there is space for optimization of treatment regimens due to poor patient ’s adherence to medication, which is usually a combination of several substances. Adherence decreases with the number of pills a patient needs to take. A combination of substances in one single-pill (single pill combination, SPC), might increase a...
Source: High Blood Pressure and Cardiovascular Prevention - March 26, 2020 Category: Cardiology Source Type: research

Prevalence of Subclinical Carotid Atherosclerosis and Role of Cardiovascular Risk Factors in Older Adults: Atherosclerosis and Aging are Not Synonyms
ConclusionHypertension and dyslipidemia are the major determinant of atherosclerosis regardless of age in our study. Our findings support the concept that aging is not necessarily synonymous with atherosclerosis and highlight the key role played by superimposed CV risk factors on arterial ‘‘bad aging’’. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - March 26, 2020 Category: Cardiology Source Type: research

Functional Improvement After Outpatient Cardiac Rehabilitation in Acute Coronary Syndrome Patients is Not Related to Improvement in Left Ventricular Ejection Fraction
AbstractIntroductionCardiac rehabilitation (CR) improves the functional capacity and the prognosis of patients with coronary artery disease.AimOur study was aimed at assessing the relationship between functional improvement (evaluated with 6-min Walk Test —6MWT) and the improvement in left ventricular ejection fraction (LVEF) after CR.MethodsWe collected data from 249 patients (age 66.79  ± 11.06 years; males 81.52%) with a recent history of Acute Coronary Syndrome that performed CR. The functional improvement after CR was expressed as the Δ between distance covered at the final versus the ...
Source: High Blood Pressure and Cardiovascular Prevention - March 26, 2020 Category: Cardiology Source Type: research

Factors Affecting Trough Plasma Dabigatran Concentrations in Patients with Atrial Fibrillation and Chronic Kidney Disease
AbstractIntroductionDabigatran is effective and widely used to prevent ischemic stroke and systemic embolism (SE) in patients with atrial fibrillation (AF). Chronic kidney disease (CKD) also has implications for choice of any medications, as it alters pharmacokinetic parameters of drugs.AimTo evaluate trough plasma dabigatran concentration (DTPC) and to analyse potential factors affecting these values in patients with AF and CKD.MethodsPatients with AF and stage 3 CKD were treated with dabigatran 110  mg or 150 mg have been included in the study and allocated into D110 or D150 group. DTPC was evaluated with high-...
Source: High Blood Pressure and Cardiovascular Prevention - March 25, 2020 Category: Cardiology Source Type: research

Central Blood Pressure Waves Assessment: A Validation Study of Non-invasive Aortic Pressure Measurement in Human Beings
AbstractIntroductionMeasurement of central (aortic) systolic blood pressure has been shown to provide reliable information to evaluate target organ damage. However, non-invasive central blood pressure measurement procedures are still under analysis.AimTo compare human pressure waveforms invasively obtained in the aorta, with the corresponding waveforms non-invasively recorded using an oscillometric device (Mobil-O-Graph).MethodsIn this research were included 20 subjects in which invasive percutaneous coronary interventions were performed. They were 10 males (68  ± 12 y. o., BMI: 27.4 ±&th...
Source: High Blood Pressure and Cardiovascular Prevention - March 25, 2020 Category: Cardiology Source Type: research

Mild Hyperuricemia: To Treat, or Not to Treat, That is the Question. Suggestions form the URRAH Study
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - March 23, 2020 Category: Cardiology Source Type: research

Hypertension Urgencies and Emergencies: The GEAR Project
AbstractAcute elevations in blood pressure (BP), usually defined as ≥ 180/110 mmHg, may present with highly heterogeneous profiles ranging from absence of symptoms to life-threatening target organ damage. In most recent years the diagnostic approach and the treatment of hypertension have gained interest by patients and physicians. The GEAR project (Gestione dell e Emergenze e urgenze in ARea critica, management of hypertensive emergencies and hypertensive urgencies in the emergency setting) was proposed by the group of Young Investigators of the Italian Society of Hypertension as a survey aimed to evaluate the aw...
Source: High Blood Pressure and Cardiovascular Prevention - March 21, 2020 Category: Cardiology Source Type: research

Association Between Nutrient Patterns and Hypertension Among Adults in the United States: A Population-Based Survey
AbstractIntroductionHypertension (HTN) is a common medical condition associated with many adverse health outcomes. Diet plays a crucial role in the pathology, prevention, and management of HTN.AimTo identify nutrient patterns (NPs) and to investigate their association with the risk of HTN among adults in the United States (US).MethodsThis cross-sectional study used data from the US community-based National Health and Nutrition Examination Survey (NHANES). Participants with data on dietary intake and blood pressure were analyzed. NPs were determined by principal components analysis (PCA). In all the analyses (analysis of co...
Source: High Blood Pressure and Cardiovascular Prevention - March 18, 2020 Category: Cardiology Source Type: research

How to Apply European and American Guidelines on High Blood Pressure in Children and Adolescents. A Position Paper Endorsed by the Italian Society of Hypertension and the Italian Society of Pediatrics
AbstractChildren are defined as hypertensive when their blood pressure values equal or exceed the 95th percentile of the blood pressure value distribution in a pediatric population, according to gender, age and height. The population on which reference tables are based is of fundamental importance to establish the threshold values for the diagnosis of hypertension in pediatric age. Before 2017, both American and European guidelines used nomograms created in the same reference population which included children of all weight classes. Given the close and well-known association between hypertension and excess weight in childh...
Source: High Blood Pressure and Cardiovascular Prevention - March 13, 2020 Category: Cardiology Source Type: research

Hyperuricemia and Risk of Cardiovascular Outcomes: The Experience of the URRAH (Uric Acid Right for Heart Health) Project
AbstractThe latest European Guidelines of Arterial Hypertension have officially introduced uric acid evaluation among the cardiovascular risk factors that should be evaluated in order to stratify patient ’s risk. In fact, it has been extensively evaluated and demonstrated to be an independent predictor not only of all-cause and cardiovascular mortality, but also of myocardial infraction, stroke and heart failure. Despite the large number of studies on this topic, an important open question that st ill need to be answered is the identification of a cardiovascular uric acid cut-off value. The actual hyperuricemia cut-o...
Source: High Blood Pressure and Cardiovascular Prevention - March 10, 2020 Category: Cardiology Source Type: research

Italian Society of Arterial Hypertension (SIIA) Position Paper on the Role of Renal Denervation in the Management of the Difficult-to-Treat Hypertensive Patient
AbstractRenal denervation is a device-based procedure for hypertension for which safety and efficacy has been demonstrated. At present, its clinical use is still matter of debate, despite the most recent clinical trials have shown promising results with new-generation devices in various hypertensive populations. This position paper was deemed necessary by the Italian Society of Arterial Hypertension, in order to provide indications about the applications of renal denervation in the clinical setting. A state-of-the art review of the literature, focusing on safety and efficacy data, is provided. Furthermore, based on current...
Source: High Blood Pressure and Cardiovascular Prevention - March 10, 2020 Category: Cardiology Source Type: research

Cardiovascular Risk in Women Deprived of Freedom from a Public Prison in Mato Grosso, Brazil
ConclusionWhen considering the ambience factor, modifiable risk factors may negatively influence the long-term health of these women, particularly in relation to the cardiovascular system. The found scenario, in relation to the cardiovascular risk, points to the need for interventions, regarding the clinical condition and life-styles adopted by this population. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - March 7, 2020 Category: Cardiology Source Type: research

Clinical Relevance of Orthostatic Hypotension in Patients with Atrial Fibrillation and Suspected Transient Ischemic Attack
This study investigates, for the first time, the association between blood pressure (BP), OH and mortality in a cohort of patients with AF and TIA symptoms.AimTo investigate the incidence of the association between OH, AF and TIA.MethodsThis retrospective observational study utilised the Leicester one-stop transient TIA clinic patient database to consider the initial systolic and diastolic BP of 688 patients with a diagnosis of AF. The primary outcome was time until death. Covariant measures included status of AF diagnosis (known or new AF), cardiovascular risk factors, and primary clinic diagnosis [cerebrovascular (CV) ve...
Source: High Blood Pressure and Cardiovascular Prevention - February 11, 2020 Category: Cardiology Source Type: research

RETRACTED ARTICLE: Vasodilatory Properties of Sacubitril/Valsartan Explored in Hypertensives Aged Over 55  Years: A Meta-Analysis
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - February 1, 2020 Category: Cardiology Source Type: research

Low Dose Resistance Exercise: A Pilot Study Examining Effects on Blood Pressure and Augmentation Index Between Intensities
ConclusionsResults suggest that changes in blood pressure and augmentation index vary depending on the intensity of resistance exercise regardless of the volume of exercise carried out. Changes in AIx75 in response to resistance exercise may be independent of changes in BP. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - January 31, 2020 Category: Cardiology Source Type: research

Gender Differences in the Pattern of Socio-Demographics Relevant to Metabolic Syndrome Among Kenyan Adults with Central Obesity at a Mission Hospital in Nairobi, Kenya
AbstractIntroductionMetabolic syndrome (MetS) is a risk factor for cardiovascular-related morbidity and mortality. Although the risk factors for MetS are well documented, differences in gender-based demographics among Kenyan adults with central obesity are lacking.AimDetermine gender differences in the pattern of socio-demographics relevant to metabolic syndrome among Kenyan adults with central obesity at a mission hospital, Nairobi.MethodsA cross-sectional baseline survey involving adults (N  = 404) with central obesity aged 18–64 years, as part of a community-based lifestyle intervention study. R...
Source: High Blood Pressure and Cardiovascular Prevention - January 25, 2020 Category: Cardiology Source Type: research

Hypertensive Mediated Organ Damage and Hypertension Management. How to Assess Beneficial Effects of Antihypertensive Treatments?
AbstractThe presence of hypertensive mediated organ damage is related to increased vascular risk and mortality and its prevention should be a therapeutic target and a surrogate marker of in/adequate blood pressure control. In old adult hypertensive patients the therapeutic target should be to prevent major cardiovascular events, but in young hypertensive subjects the focus should be pointed on preventing the development of hypertensive mediated organ damage, since most of the hard events are preceded by functional and structural tissues injury. Hypertension Guidelines of the European Society of Cardiology and European Soci...
Source: High Blood Pressure and Cardiovascular Prevention - January 23, 2020 Category: Cardiology Source Type: research

Evaluation of Serum Urocortin 2 Levels in Patients with Hypertension
AbstractIntroductionUrocortin 2 (UCN2), is an endogenous stress-related peptide belonging to the corticotropin-releasing factor (CRF) family, has a major role in the pathogenesis of congestive heart failure, ischemic heart disease, and hypertension.AimTo investigate the role of UCN2 levels in patients with hypertension (HTN).MethodsSerum UCN2 levels measured by ELISA were compared between patients with HTN (n  = 86) and nonHTN (n = 53).ResultsEighty-six patients with HTN [median age 66 (45 –76); 38 men] and 53 patients with non-HTN [median age 62 (40–80); 39 men] were included into t...
Source: High Blood Pressure and Cardiovascular Prevention - January 10, 2020 Category: Cardiology Source Type: research

From Endothelium to Lipids, Through microRNAs and PCSK9: A Fascinating Travel Across Atherosclerosis
AbstractLipids and endothelium are pivotal players on the scene of atherosclerosis and their interaction is crucial for the establishment of the pathological processes. The endothelium is not only the border of the arterial wall: it plays a key role in regulating circulating fatty acids and lipoproteins and vice versa it is regulated by these lipidic molecules thereby promoting atherosclerosis. Inflammation is another important element in the relationship between lipids and endothelium. Recently, proprotein convertase subtilisin/kexin type 9 (PCSK9) has been recognized as a fundamental regulator of LDL-C and anti-PCSK9 mon...
Source: High Blood Pressure and Cardiovascular Prevention - January 10, 2020 Category: Cardiology Source Type: research

PAIT-Survey Follow-Up: Changes in Albuminuria in Hypertensive Diabetic Patients with Mild-Moderate Chronic Kidney Disease
AbstractIntroductionAlbuminuria is an early marker of kidney disease and reduction of albuminuria translates into a decreased occurrence of cardiovascular and renal outcomes.AimsTo evaluate  the changes in the prevalence of albuminuria in diabetic hypertensive patients treated with several combinations of renin-angiotensin aldosterone system with calcium channel blockers.MethodsWe analysed data from  668 unselected patients from the PAIT survey (mean age 60.4 ± 10.2 years, prevalence of males 38%), with and without albuminuria, maintained for 6 months with the previous treatment wit...
Source: High Blood Pressure and Cardiovascular Prevention - January 9, 2020 Category: Cardiology Source Type: research

Blood Pressure Targets Achievement According to 2018 ESC/ESH Guidelines in Three European Excellence Centers for Hypertension
AbstractIntroductionThe most recent European guidelines on hypertension redefined office blood pressure (BP) treatment targets according to age strata and cardiovascular (CV) risk profile.AimTo evaluate proportions of adult outpatients achieving office BP treatment targets recommended by current compared to previous hypertension guidelines.MethodsWe extracted data from medical databases of adult outpatients followed in three excellence centers in hypertension (Rome, Italy; L ’Aquila, Italy; Valencia, Spain). Office BP treatment targets were defined according to either 2013 ESH/ESC guidelines (
Source: High Blood Pressure and Cardiovascular Prevention - January 8, 2020 Category: Cardiology Source Type: research

Effects of Oral Magnesium Supplementation on Vascular Function: A Systematic Review and Meta-analysis of Randomized Controlled Trials
AbstractIntroductionThe effects of magnesium (Mg) supplementation on vascular function have been evaluated in some randomized controlled trials (RCT) but their results are conflicting.AimA  systematic review and meta-analysis were conducted to summarize the effects of oral Mg supplementation on vascular function in RCT.MethodsThe databases MEDLINE (PubMed), Embase, Web of Science and Cochrane Library were accessed from inception to May 27, 2019. Intergroup differences (treatment vs. control group) related to changes in flow-mediated dilation (FMD) and pulse wave velocity (PWV), expressed as mean and standard deviation...
Source: High Blood Pressure and Cardiovascular Prevention - December 16, 2019 Category: Cardiology Source Type: research

Parental Perception of Children ’s Weight Status: Love Overpasses Scientific Evidence! A Cross-Sectional Observational Study
ConclusionsA high percentage of children is overweight or obese and almost half of parents classified their weight status incorrectly. Increasing children ’s body mass index percentiles decreases the probability to be correctly classified. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - December 5, 2019 Category: Cardiology Source Type: research

Antihypertensive Prescribing Pattern in Older Adults: Implications of Age and the Use of Dual Single-Pill Combinations
This study evaluated antihypertensive prescribing patterns in older adults ( ≥ 65 years) versus young adults based on the current guidelines with an emphasis on the use of dual single-pill combinations (SPCs).MethodsA nationwide audit of 8746 primary care prescriptions of hypertensive patients with comorbidities in Bahrain was performed.ResultsAntihypertensive combination therapy was prescribed more often to older (77.1%) than young adults (68.6%;P  
Source: High Blood Pressure and Cardiovascular Prevention - December 3, 2019 Category: Cardiology Source Type: research

Comments About: Prognostic Significance of Heart Rate and Beta-Blocker Use in Sinus Rhythm in Patients with Heart Failure and Preserved Ejection Fraction
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - November 21, 2019 Category: Cardiology Source Type: research

Hypertension Control Rate Should be Defined Consistently and Used to Motivate Action to Improve
AbstractHypertension has been poorly controlled with the old target of less than 140/90 (mmHg). Currently, the average control rate in the United States is about 50% with the old goal of 140/90. If the new goal of 130/80 is used, the control rate would dramatically decrease. For hypertension management, the traditional stepped-care method needs to be replaced with new approaches using single-pill combination pharmacotherapy (polypill) or using hemodynamic data for drug selection and titration to target underlying cardiovascular abnormalities when cardiovascular disease is present. With the old goal of 140/90, these new app...
Source: High Blood Pressure and Cardiovascular Prevention - November 19, 2019 Category: Cardiology Source Type: research

Immigration Emergency in Italy: The Impact of Socioeconomic Status on Blood Pressure Levels and Control
AbstractIntroductionNowadays there are more than 5 millions of immigrants (8.3% of general adult population) in Italy.AimTo evaluate the potential impact of immigration and the possession of a permanent residence on blood pressure (BP) levels and control in a low income population of immigrants from different countries.MethodsWe evaluated clinical characteristics and social status of adult individuals with known diagnosis of hypertension afferent to thePoliambulatorio della Caritas Diocesana in Rome, Italy, between 2010 –2016. Subjects were stratified according to their macro-areas of origin (Europe, Asia, Africa, So...
Source: High Blood Pressure and Cardiovascular Prevention - November 18, 2019 Category: Cardiology Source Type: research

Psychosocial Factors and Personality Traits and the Prevalence of Arterial Hypertension Among 35- and 55-Year-Old Men and Women in Sweden and Estonia: a SWESTONIA Longitudinal Study
AbstractIntroductionPsychosocial factors influence the risk of developing hypertension. Personality traits have a modulating effect against the harmful influences of psychosocial factors.AimThrough a longitudinal clinical study consisting of men and women aged 35 and 55 at the baseline in Estonia and Sweden, to assess the influence of psychosocial factors and personality traits resulting in arterial hypertension.MethodsData analysis based on the cross-sectional study with 2 assessments over 13  years of a sample comprising 158 individuals from Estonia and 213 individuals from Sweden. The Pearlin Mastery Scale, Rosenbe...
Source: High Blood Pressure and Cardiovascular Prevention - November 18, 2019 Category: Cardiology Source Type: research

The Impact of Measurement Methods on Office Blood Pressure and Management of Hypertension in General Practice
AbstractIntroductionThe use of unattended automated office blood pressure (uAutoOBP) versus attended automated (aAutoOBP) and manual auscultatory office blood pressure (AuscOBP) measurements is a topic of current controversy.AimTo evaluate the differences between OBP measurements methods in the general practice (GP) setting.MethodsWe first compared aAutoOBP and uAutoOBP in 42 consecutive patients with hypertension (group 1). Secondly, we compared AuscOBP to uAutoOBP measurements in 133 consecutive patients with hypertension (group 2). In addition, we analyzed the achieved OBP targets as recommended in the 2018 European Soc...
Source: High Blood Pressure and Cardiovascular Prevention - November 9, 2019 Category: Cardiology Source Type: research

Impact of Methodological and Calibration Approach on the Association of Central and Peripheral Systolic Blood Pressure with Cardiac Structure and Function in Children, Adolescents and Adults
AbstractIntroductionPeripheral and aortic systolic blood pressure (pSBP and aoSBP) were measured using different methodological and calibration approaches to analyze the association and agreement between pSBP and/or aoSBP, and the association of pSBP and aoSBP with left ventricle (LV) and atrium (LA) structural –functional characteristics.MethodsIn healthy subjects (n  = 269, age: 9–85 years; n = 147, age 
Source: High Blood Pressure and Cardiovascular Prevention - October 30, 2019 Category: Cardiology Source Type: research

Subclinical Organ Damage in Children and Adolescents with Hypertension: Current Guidelines and Beyond
AbstractHigh blood pressure (BP) is becoming a growing health issue even in children and adolescents. Moreover, BP elevation in youth frequently translates into children and adult hypertension contributing to the development of cardiovascular disease. The detection of early markers of vascular damage, potentially leading to overt cardiovascular disease, is important for clinical decisions about if and how to treat hypertension and can be useful in monitoring the effectiveness of the treatment. The purpose of this review is to summarize the actual knowledge about subclinical organ damage (SOD) in hypertensive children and a...
Source: High Blood Pressure and Cardiovascular Prevention - October 24, 2019 Category: Cardiology Source Type: research

Evaluation of Unattended Automated Office, Conventional Office and Ambulatory Blood Pressure Measurements and Their Correlation with Target Organ Damage in an Outpatient Population of Hypertensives: Study Design and Methodological Aspects
AbstractAccurate measurement of blood pressure (BP) has a pivotal role in the management of patients with arterial hypertension. Recently, introduction of unattended office BP measurement has been proposed as a method allowing more accurate management of hypertensive patients and prediction of hypertension-mediated target organ damage (HMOD). This approach to BP measurement has been in particular proposed to avoid the white coat effect (WCE), which can be easily assessed once both attended and unattended BP measurements are obtained. In spite of its interest, the role of WCE in predicting HMOD remains largely unexplored. T...
Source: High Blood Pressure and Cardiovascular Prevention - October 17, 2019 Category: Cardiology Source Type: research

Prognostic Significance of Heart Rate and Beta-Blocker Use in Sinus Rhythm in Patients with Heart Failure and Preserved Ejection Fraction
ConclusionsHR is independently associated with increased all-cause mortality in SR and a lower HR ( ≤ 60 bpm) is favorable for better outcome in HFpEF patients with SR. Beta-blocker use is associated with reduced mortality and a lower HR is associated with reduced mortality in HFpEF patients with SR. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - October 17, 2019 Category: Cardiology Source Type: research

Effect of CYP3A4 , CYP3A5 , ABCB1 Gene Polymorphisms on Rivaroxaban Pharmacokinetics in Patients Undergoing Total Hip and Knee Replacement Surgery
AbstractIntroductionPopulation ageing in developed countries will inevitably increase the need for knee and hip replacement surgery. Over the years, direct oral anticoagulants, such as rivaroxaban, have been widely used for thromboprophylaxis in patients undergoing knee and hip replacement surgery. The study of pharmacogenetic characteristics of rivaroxaban is important for enhancing the effectiveness and safety of rivaroxaban thromboprophylaxis.AimEvaluation ofCYP3A4,CYP3A5 andABCB1 gene polymorphisms influence on rivaroxaban pharmacokinetics and prothrombin time dynamics in patients undergoing total hip and knee replacem...
Source: High Blood Pressure and Cardiovascular Prevention - October 15, 2019 Category: Cardiology Source Type: research

Left Ventricular Myocardial Performance in Normotensive Offspring of Hypertensive Parents
AbstractIntroductionEarly alterations in the cardiovascular system have been described in offspring of hypertensive parents, but with conflicting results.AimTo evaluate the influence of genetic predisposition to hypertension on left ventricular (LV) geometry and function, 30 normotensive male offspring of hypertensive parents (EH+) and 30 matched offspring of normotensive families (EH −), were studied.MethodsAll subjects underwent office and 24-h ambulatory blood pressure monitoring (ABPM), conventional and Tissue Doppler Echocardiography (TDE), including assessment of myocardial performance index (MPI).ResultsEH+ sh...
Source: High Blood Pressure and Cardiovascular Prevention - October 14, 2019 Category: Cardiology Source Type: research

Blood Pressure Variability and Therapeutic Implications in Hypertension and Cardiovascular Diseases
AbstractBlood pressure (BP) is characterized by continuous dynamic and spontaneous oscillations occurring over lifetime and defining the so-called blood pressure variability (BPV). BPV has been associated with target organ damage, cardiovascular (CV) risk and death, suggesting the use of BPV as a new target in hypertension management in addition to mean BP values lowering. The purpose of the review is to focus on the therapeutic implications of BPV and summarize the effects of different drug classes on various types of BPV. Despite most first-line antihypertensive medications contribute to reduce both short and long term B...
Source: High Blood Pressure and Cardiovascular Prevention - September 26, 2019 Category: Cardiology Source Type: research

Selected Abstracts from XXXVI National Congress of the Italian Society of Hypertension (SIIA), Rome, 26 –28 September 2019
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - September 25, 2019 Category: Cardiology Source Type: research