Inflammation and Vascular Ageing: From Telomeres to Novel Emerging Mechanisms
AbstractCardiovascular disease (CVD) remains the leading cause of morbility and mortality worldwide. The identification of common cardiovascular risk factors has led to the development of effective treatments that enabled a significant reduction of the global cardiovascular disease burden. However, a significant proportion of cardiovascular risk remains unexplained by these risk factors leaving many individuals at risk of cardiovascular events despite good control of the risk factors. Recent randomized clinical trials and Mendelian randomization studies have suggested that inflammation explains a significant proportion of ...
Source: High Blood Pressure and Cardiovascular Prevention - July 19, 2019 Category: Cardiology Source Type: research

Impact of Lipid-Lowering Therapy on Mortality According to the Baseline Non-HDL Cholesterol Level: A Meta-Analysis
The objective of this meta-analysis was to define the impact of lipid-lowering therapy on the reduction of total and cardiovascular mortality by different baseline levels of non-HDL-C.MethodsWe performed a meta-analysis including randomized, controlled clinical trials of lipid-lowering therapy, reporting mortality with a minimum of 6  months of follow-up, searching in PubMed/Medline, EMBASE and Cochrane Clinical Trials databases. The random-effects model and meta-regression were performed.ResultsTwenty nine trials of lipid-lowering drugs, including 233,027 patients, were considered eligible for the analyses. According...
Source: High Blood Pressure and Cardiovascular Prevention - July 16, 2019 Category: Cardiology Source Type: research

Left Atrial Strain for Predicting Atrial Fibrillation Onset in Hypertensive Patients
AbstractIntroductionWe aimed to find new predictive parameters for atrial fibrillation (AF) onset in hypertensive patients using two-dimensional (2D) conventional and speckle tracking echocardiography of the left atrium (LA).MethodsOne hundred and eight patients with essential hypertension (HTN) were prospectively enrolled, from which 67 patients had no other important comorbidities (HTN group), while 41 patients had a recent AF episode, but were in sinus rhythm at the moment of enrollment (HTN and AF group). LA diameters and maximal volume, LV mass, LV ejection fraction and diastolic function were assessed through 2D conv...
Source: High Blood Pressure and Cardiovascular Prevention - July 15, 2019 Category: Cardiology Source Type: research

Does A Therapy for Reflex Vasovagal Syncope Really Exist?
AbstractSyncope is a temporary loss of consciousness due to transient global cerebral hypoperfusion. Reflex syncope is the most frequent, representing 21% of all types of syncopal events, and includes: (a) the vasovagal syncope (classical type); (b) the situational syncope; (c) the carotid sinus syncope and (d) non-classical forms. An accurate anamnesis and physical examination are fundamental for the diagnosis. Although limited evidence is available regarding the efficacy of some treatments, a number of these can be successfully used in the clinical practice. It is, however, important to personalize the therapeutic approa...
Source: High Blood Pressure and Cardiovascular Prevention - July 11, 2019 Category: Cardiology Source Type: research

Attended Versus Unattended Automated Office Blood Pressure: A Systematic Review and Meta-analysis
AbstractIntroductionAutomated office blood pressure (AOBP) has been proposed for blood pressure (BP) assessment in the office because it shows a strong association with the awake ambulatory BP. However, it remains unknown whether the presence or absence of an observer modulates AOBP readings.AimTo determine the difference between unattended and attended AOBP measurements through systematic review and meta-analysis.MethodsWe searched the PubMed and the Cochrane Collaboration Library and we screened the references ’ list of relevant reports to identify potentially eligible articles. For included studies, quality was as...
Source: High Blood Pressure and Cardiovascular Prevention - July 9, 2019 Category: Cardiology Source Type: research

Should We Increase Trust in Cardiovascular Prevention?
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - July 9, 2019 Category: Cardiology Source Type: research

Aspirin Efficacy in Primary Prevention: A Meta-analysis of Randomized Controlled Trials
AbstractIntroductionThe role of aspirin as a means of primary prevention remains controversial.AimWe have conducted a meta-analysis of all randomized controlled trials (RCTs) to evaluate the role of aspirin in primary prevention.MethodsLiterature search was performed via PubMed, Embase, and the Cochrane Library for all related RCTs. All-cause mortality was the primary endpoint. Secondary endpoints included major adverse cardiovascular events (MACE), myocardial infarction (MI), cardiovascular mortality, cerebrovascular events, and bleeding events. We used a random effects model to report the risk ratios (RRs) with 95% confi...
Source: High Blood Pressure and Cardiovascular Prevention - July 6, 2019 Category: Cardiology Source Type: research

The Effects of Resveratrol Supplementation on Endothelial Function and Blood Pressures Among Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
ConclusionsResveratrol supplementation significantly increased FMD among patients with MetS and related disorders, but did not affect SBP and DBP. Additional prospective studies are needed to investigate the effect of resveratrol supplementation on endothelial function and blood pressures, using higher-dose of resveratrol with longer durations. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - July 1, 2019 Category: Cardiology Source Type: research

Low Density Lipoprotein (LDL) Cholesterol as a Causal Role for Atherosclerotic Disease: Potential Role of PCSK9 Inhibitors
AbstractProprotein convertase subtilisin/kexin type 9 (PCSK9)-related discoveries of the turn of the century have translated into substantial novelty in dyslipidemia treatment in the last 5  years. With chronic preventable atherosclerotic cardiovascular diseases (ASCVD) representing an epidemic of morbidity and mortality worldwide, low-density lipoprotein cholesterol (LDL-c) reduction represents a public health priority. By overcoming two major statin-related issues, namely intoleranc e and ineffectiveness, PCSK9 inhibitors have offered a safe and effective option in selected clinical settings where LDL-c reduction is...
Source: High Blood Pressure and Cardiovascular Prevention - June 24, 2019 Category: Cardiology Source Type: research

Is the Oral Microbiome Associated with Blood Pressure in Older Women?
AbstractIntroductionA possible role of the oral microbiome, specifically oral nitrate reducing flora, in blood pressure (BP) homeostasis, if proven etiologic in nature, could lead to novel mechanism-based therapy to improve hypertension prevention and control.AimThis cross-sectional study characterized and compared the oral microbiome between four study groups based on BP status among 446 postmenopausal women aged 53 –82 years.MethodsThree study groups were not taking hypertension medication and were separated based on BP, as follows: normal BP (systolic    90; N = 42). The forth grou...
Source: High Blood Pressure and Cardiovascular Prevention - June 24, 2019 Category: Cardiology Source Type: research

Avoidable Burden of Cardiovascular Diseases in the Eastern Mediterranean Region: Contribution of Selected Risk Factors for Cardiovascular-Related Deaths
ConclusionsFindings suggest that health policy makers of all EMRO countries should take into account the attributable burden of CVD-related mortality due to associated risk factors to effectively develop preventive interventions. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - June 21, 2019 Category: Cardiology Source Type: research

Chinese Physicians ’ Perspectives on the 2017 American College of Cardiology/American Heart Association Hypertension Guideline: A Mobile App-Based Survey
ConclusionsDifferent understanding of hypertension prevention and treatment exists among Chinese physicians. It is an emergent need to form an evidence-based authoritative answer to guide Chinese physicians ’ future clinical practice. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - June 14, 2019 Category: Cardiology Source Type: research

Vascular Aging and Disease of the Small Vessels
AbstractCardiovascular events are the consequence of vascular damage at both the macro and microcirculatory level. The relationship between large stiffening artery and microvascular disease may be bidirectional, since wave reflection from microvascular sites could increase systolic blood pressure and pulse pressure, while transmission of increased arterial pulsatility to microvessels could represent a mechanism of damage. Hypertension and aging share similar mechanisms of vascular dysfunction. In fact, vascular remodelling, endothelial dysfunction and vascular stiffness are common features in hypertension and aging. Struct...
Source: High Blood Pressure and Cardiovascular Prevention - May 29, 2019 Category: Cardiology Source Type: research

Commentary to “The Possible Role of Nutraceuticals in the Prevention of Cardiovascular Disease”
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - May 7, 2019 Category: Cardiology Source Type: research

Vascular Aging and Disease of the Large Vessels: Role of Inflammation
AbstractStructural and functional arterial properties commonly impair with aging process. These effects on vasculature could act at many levels from microcirculation to large vessels. Above normal aging process classic cardio-vascular risk factors (hypertension, diabetes mellitus, dyslipidemia, etc.) accelerate the physiological process leading to premature structural and functional alterations that has also been termed early vascular aging. Target organ damage evaluation could be clinically important since these alterations precede by many years ’ cardiovascular events and so their assessment can predict the onset o...
Source: High Blood Pressure and Cardiovascular Prevention - May 3, 2019 Category: Cardiology Source Type: research

Prevention of Cardiovascular Diseases in Children and Adolescents
AbstractThe atherosclerotic alterations that are the basis of cardiovascular diseases can start already in childhood. For this reason the prevention of cardiovascular diseases should be undertaken very early both in the general population and, in a targeted manner, in subjects at cardiovascular risk. Preventive strategies should include measures to encourage physical activity and correct eating habits and to reduce exposure to pollutants. The main actors responsible for carrying out these preventive interventions are the local and national political authorities. Moreover, particular attention should be paid to the first th...
Source: High Blood Pressure and Cardiovascular Prevention - April 30, 2019 Category: Cardiology Source Type: research

Prevalence and Risk Factors of Hypertension in the Vietnamese Elderly
AbstractIntroductionHypertension (HT) is considered as a major determinant of cardiovascular complications. However, few studies have addressed HT prevalence among adults aged 60  years and older in the northern mountainous region of Vietnam.AimTo determine the prevalence of HT and its risk factors in the elderly in that area.MethodsA cross-sectional study was conducted in a study area in the northern of Vietnam. We interviewed 354 adults aged 60  years or over who were randomly selected, and then measured their blood pressure.ResultsThe overall HT prevalence was 62.15%. The isolated systolic hypertension (ISH) p...
Source: High Blood Pressure and Cardiovascular Prevention - April 24, 2019 Category: Cardiology Source Type: research

Morning Surge and Peak Morning Ambulatory Blood Pressure Versus Automated Office Blood Pressure in Predicting Cardiovascular Disease
AbstractIntroductionAutomated office blood pressure (AOBP) has been recently shown to predict equally well to ambulatory blood pressure (ABP), conventional office blood pressure (OBP) and home blood pressure (HBP), cardiovascular (CV) events among hypertensives.AimTo compare AOBP recording and ABP monitoring in order to evaluate morning blood pressure (BP) peak in predicting CV events and deaths in hypertensives.MethodsWe assessed 236 initially untreated hypertensives, examined between 2009 and 2013. The end points were CV and non-CV death and any CV event including myocardial infarction, evidence of coronary heart disease...
Source: High Blood Pressure and Cardiovascular Prevention - April 15, 2019 Category: Cardiology Source Type: research

Vasodilatory Properties of Sacubitril/Valsartan Explored in Hypertensives Aged Over 55  Years: A Meta-Analysis
AbstractIntroductionA complete assessment of the efficacy and safety of sacubitril/valsartan for hypertension is not available yet.MethodsTherefore, we performed a meta-analysis of randomized controlled trials (RCTs) by incorporating only RCTs including patients aged> 55 years in which the antihypertensive efficacy and safety of sacubitril/valsartan were compared with those of a reference drug (comparator). The mean reductions in systolic blood pressure and diastolic blood pressure in the sitting position (msSBP and msDBP, respectively)were assumed as primary efficacy endpoints. Even mean reduction in ambulatory systoli...
Source: High Blood Pressure and Cardiovascular Prevention - April 1, 2019 Category: Cardiology Source Type: research

Kounis Syndrome: Report of Two Cases with Peculiar Presentation and Diagnostic Issues
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - March 25, 2019 Category: Cardiology Source Type: research

Abstracts from the 17th National Congress of the Italian Society of Cardiovascular Prevention (SIPREC), Naples, 21 –23 March 2019
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - March 16, 2019 Category: Cardiology Source Type: research

Pharmacology of Nutraceuticals with Lipid Lowering Properties
AbstractLowering total and, in particular, LDL cholesterol reduces cardiovascular risk and clinical events. Cholesterol-lowering strategies are manifold. Better diets and positive lifestyle changes are the foremost approach; the use of functional foods, of food supplements/nutraceuticals, and pharmacological treatment must be considered in patients with increasing lipid abnormalities and or increasing cardiovascular risk. Here, we briefly review the most frequently occurring cholesterol-lowering substances found in functional foods or nutraceuticals, i.e. plant sterols and stanols, monacolin K found in red yeast rice, berb...
Source: High Blood Pressure and Cardiovascular Prevention - March 15, 2019 Category: Cardiology Source Type: research

Latest Updates on Lipid Management
AbstractAtherosclerotic cardiovascular disease (ASCVD) is the leading cause of death worldwide. Despite the clinical long-term and near-term benefits of lowering cholesterol in, respectively, primary and secondary prevention of ASCVD, cholesterol levels remain under-treated, with many patients not achieving their recommended targets. The present article will review the latest updates on lipid management with emphases on the different classes of cholesterol-lowering agents and their clinical uses. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - March 15, 2019 Category: Cardiology Source Type: research

The Key Role of CT for Success of Adrenal Venous Sampling Illustrated by a Unique Clinical Case
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - March 11, 2019 Category: Cardiology Source Type: research

The Possible Role of Nutraceuticals in the Prevention of Cardiovascular Disease
AbstractCardiovascular diseases (CVDs) are the main causes of mortality and disability worldwide. Although the initial therapeutic approach to improve the main cardiovascular (CV) risk factors is based on nonpharmacological measures, mainly lifestyle modifications, compliance to recommendations is often poor and inadequate. Therefore, in recent years the use of several nutraceuticals, i.e., nutrients and/or bioactive compounds of plant or microbial origin with potentially healthful effects, has become widespread. However, to date, the scientific data on the possible benefits of the use of nutraceuticals are still inconclus...
Source: High Blood Pressure and Cardiovascular Prevention - February 27, 2019 Category: Cardiology Source Type: research

Trisomy of the Short Arm of Chromosome 12 Associated with High Cardiovascular Risk: A Case Report
AbstractTrisomy of the short arm of chromosome 12 is a rare genetic disease characterised by dysmorphic features, mental retardation, behavioural disorders, seizures predisposition and other congenital abnormalities. Arterial hypertension is not a characteristic feature of 12p trisomy, although congenital heart defects are reported. In this case report, we present a young patient with incomplete trisomy 12p, analysing some characteristics of this disease that have not been previously described in literature. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - February 26, 2019 Category: Cardiology Source Type: research

Common Carotid Artery Calcification Impacts on Cognitive Function in Older Patients
AbstractIntroductionCognitive impairment and dementia represent an emerging health problem. Cardiovascular (CV) risk factors contribute to cognitive impairment.AimTo investigate the effect of vascular calcification on cognitive impairment and dementia, independently of plaque and traditional CV risk factors.MethodsFour hundred and sixty-nine patients (age of 78.6  ± 6.1 years, 74.4% women) were studied. Traditional CV risk factors levels, cognitive function (MMSE), brain CT scan, and other vascular parameters were measured. Common Carotid Artery (CCA) plaque and calcification were evaluated by ult...
Source: High Blood Pressure and Cardiovascular Prevention - February 18, 2019 Category: Cardiology Source Type: research

The Unsolved Conundrum of Optimal Blood Pressure Target During Acute Haemorrhagic Stroke: A Comprehensive Analysis
AbstractIntracerebral haemorrhage (ICH) is a devastating cerebrovascular disease, which accounts to 15% of all strokes. Among modifiable risk factors for ICH, hypertension is the most frequent. High blood pressure (BP) is detected in more than 75 –80% of patients with ICH. Extremely elevated BP has been associated with early hematoma growth, a relatively frequent occurrence and powerful predictor of poor outcome in patients with spontaneous ICH. On the other hand, excessively low BP might cause cerebral hypoperfusion and ultimately lead to poor outcome. This review will analyse the most important trials that have tri...
Source: High Blood Pressure and Cardiovascular Prevention - February 18, 2019 Category: Cardiology Source Type: research

Multiple Cardiovascular Risk Factors Indicate Cardiovascular Disease in Stage 1 Hypertension
AbstractIn November 2017, the American College of Cardiology and American Heart Association released new guidelines on hypertension that lowered the blood pressure (BP) definition of stage 1. Impedance cardiography (ICG) has shown that ventricular, vascular, and hemodynamic abnormalities are prevalent in adults over 40  years of age with at least 2 cardiovascular (CV) risk factors. This suggests that all stage 1 hypertension patients with multiple CV risk factors, over 40 years of age, have earlystage CV disease and should be treated. For many of these patients, ICG testing has shown low cardiac index with high s yste...
Source: High Blood Pressure and Cardiovascular Prevention - February 5, 2019 Category: Cardiology Source Type: research

Reviewers 2018
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - January 31, 2019 Category: Cardiology Source Type: research

Risk Factors Associated with Failure to Achieve the Low Density Lipoprotein Cholesterol Therapeutic Target in Patients with Acute Coronary Syndrome: A Longitudinal, Single Centre Investigation
AbstractIntroductionReducing low-density lipoprotein cholesterol (LDL-C) to target  
Source: High Blood Pressure and Cardiovascular Prevention - January 25, 2019 Category: Cardiology Source Type: research

Vitamin D and Ischaemic Heart Disease: A Casual or A Causal Association?
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - January 23, 2019 Category: Cardiology Source Type: research

Nutrients and Nutraceuticals for the Management of High Normal Blood Pressure: An Evidence-Based Consensus Document
AbstractEssential hypertension still represents the most common cardiovascular risk factor, which is responsible for the vast majority of global burden of disease, worldwide. Antihypertensive treatment aimed at lowering blood pressure (BP) levels to the recommended therapeutic targets has demonstrated to reduce risk of developing major cardiovascular, cerebrovascular and renal complications. Despite these evidence, overall rates of BP control are dramatically low in most European and Western countries, as well as in the so called developing countries, thus contributing to the increasingly amount of hypertension-related cos...
Source: High Blood Pressure and Cardiovascular Prevention - January 22, 2019 Category: Cardiology Source Type: research

Emergency Department-Provided Home Blood Pressure Devices Can Help Detect Undiagnosed Hypertension
ConclusionsFor patients with elevated BP in the ED, HBPM could be valuable for determining which patients have HTN and require expedient follow-up. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - January 19, 2019 Category: Cardiology Source Type: research

Assessment of the Perceived Relationship Between Healthy Nutrition and Cardiovascular Diseases by the Adult Czech Population
ConclusionIn order to increase the efficiency of preventive measures, the transfer of theoretical knowledge to the lay public must be accompanied by interventions aimed at information repetition, motivation, and establishment of partnerships with health care providers. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - January 18, 2019 Category: Cardiology Source Type: research

Highlights of ESC/ESH 2018 Guidelines on the Management of Hypertension: What Every Doctor Should Know
AbstractThis is a review article aiming to make focus on the changes made in the most recent sets of clinical recommendations and indications from European Society of Cardiology (ESC)/European Society of Hypertension (ESH) guidelines  for the management of arterial hypertension. In particular, in this article we attempted to focus on the main new elements introduced in order to meet the need of doctors to adhere to guidelines and to provide their patients with the most updated recommendations for the clinical management of hypertension. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - January 2, 2019 Category: Cardiology Source Type: research

Association of Vitamin D Deficiency with Chronic Stable Angina: A Case Control Study
ConclusionThere is a significant association between vitamin D deficiency and the occurrence of chronic stable angina. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - December 26, 2018 Category: Cardiology Source Type: research

Hypertension is Common in Patients with Newly Diagnosed Acromegaly and is Independently Associated with Renal Resistive Index
ConclusionsIn patients with newly diagnosed acromegaly, HT frequency was significantly increased and it was independently associated with the RRI value. Therefore, these patients should be closely monitored for HT —the most frequent and important cardiovascular risk factor—and treated before they develop target organ damage. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - December 7, 2018 Category: Cardiology Source Type: research

Increasing Quality of  Secondary Prevention of Acute Myocardial Infarction by Using E-Health
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - December 1, 2018 Category: Cardiology Source Type: research

Measuring Central or Peripheral Blood Pressure Levels? That is the Question in the Modern Clinical Practice of Hypertension
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - November 30, 2018 Category: Cardiology Source Type: research

Is it Possible to Significantly Modify Blood Pressure with a Combined Nutraceutical on Top of a Healthy Diet? The Results of a Pilot Clinical Trial
ConclusionsThe tested nutraceutical composite reduces systolic and diastolic blood pressure in the medium term, leading to a significant reduction in the estimated cardiovascular risk in a sample of patients with pre-hypertension or first-degree hypertension. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - November 23, 2018 Category: Cardiology Source Type: research

Hypertension Management at Older Age: An Update
AbstractHypertension is a risk factor for cardiovascular morbidity and mortality with increasing prevalence with age, whose treatment is associated with benefits over fatal and non-fatal cardiovascular events even later in life. However, there are persistent concerns on the short- and long-term weighted benefits of treating hypertension in the very old, particularly in those with specific clinical features. In fact, a broad range of clinical scenarios can be observed at older ages, spanning from the healthy to the frailest patient, and hypertension clinical trials have traditionally excluded the latter, thus preventing the...
Source: High Blood Pressure and Cardiovascular Prevention - November 22, 2018 Category: Cardiology Source Type: research

Effect of Primary Hypertension on Treatment Outcomes of Patients with Postmenopausal Osteoporosis: A 5 Year Follow Up Retrospective Study
AbstractAimTo investigate the efficacy of primary hypertension (HTN) on the treatment prognosis of patients with postmenopausal osteoporosis (PMOP).Methods45 patients who were diagnosed as PMOP with lumbar and/or femur neck bone mineral density screening (BMD) but have no history of PMOP treatment including calcium and vitamin D, have comorbid primary HTN and treated with a vasodilator antihypertensive drug at least a year were included to the study. Control group was constituted with 44 patients with PMOP at same age but have no comorbidity. Demographic features including age, height, weight, occupation, educational level...
Source: High Blood Pressure and Cardiovascular Prevention - November 22, 2018 Category: Cardiology Source Type: research

The Contribution of Poliomyelitis to President Roosevelt ’s Heart Failure. A Lesson on the Importance of Vaccinations for Cardiovascular Prevention
(Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - November 19, 2018 Category: Cardiology Source Type: research

Secondary Arterial Hypertension: From Routine Clinical Practice to Evidence in Patients with Adrenal Tumor
AbstractPrevalence of arterial hypertension is up to 30 –40% in epidemiological studies, it increases with aging and affects the cardiovascular risk. Essential form of hypertension is the most frequent; however, 5–10% of patients are affected by a specific and potentially reversible cause of increased blood pressure levels, called secondary hypertens ion. In general, all patients with young onset-age (
Source: High Blood Pressure and Cardiovascular Prevention - November 10, 2018 Category: Cardiology Source Type: research

Effect of Amlodipine/Valsartan Versus Nebivolol/Valsartan Fixed Dose Combinations on Peripheral and Central Blood Pressure
AbstractIntroductionAlthough hypertensive drugs may have the same effect on peripheral blood pressure, they vary in their effect on central blood pressure and its indices.AimTo evaluate efficacy of fixed-dose combination of amlodipine 10  mg/valsartan 160 mg versus nebivolol 5 mg/valsartan 160 mg in grade 2 or more hypertensive patients assessed by peripheral and central blood pressure.MethodsA prospective, open label, randomized study done in the outpatient cardiology clinic at Beni-Suef University Hospital. A total of 137 patients continued the study; group I (n  = 75) received Amlodipin...
Source: High Blood Pressure and Cardiovascular Prevention - November 3, 2018 Category: Cardiology Source Type: research

Left Ventricular Hypertrophy in Hypertensive Athletes can be Reduced by Antihypertensive Medication Despite Continuing Intense Aerobic Exercise
AbstractIntroductionLeft ventricular hypertrophy (LVH) can be successfully reduced by antihypertensive medication. Both hypertension and aerobic exercise can cause increases in left ventricular mass (LV-mass).AimTherefore, hypertensive athletes with LVH were studied to investigate the effect of antihypertensive medication on LV-mass reduction despite continuing their regular intensive exercise programs.Methods14 previously untreated hypertensive male athletes (A) with LVH and a prolonged history of endurance training where included in the study. 50 previously untreated inactive comparable hypertensives with LVH served as c...
Source: High Blood Pressure and Cardiovascular Prevention - October 20, 2018 Category: Cardiology Source Type: research

Blood Pressure Control and Other Quality of Care Metrics for Patients with Obesity and Diabetes: A Population-Based Cohort Study
ConclusionsAlthough the cardiovascular risk for patients with obesity and diabetes is greater than for non-obese patients with diabetes, we found that patients with obesity are even further behind in achieving blood pressure control. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - October 16, 2018 Category: Cardiology Source Type: research

Hypertensive Crisis with Neurological Impairment Mimicking a Guillain –Barrè Syndrome: Searching for a Link
We describe a case of a 62-year-old woman presented to the emergency department for hypertensive crisis with symmetric flaccid paralysis, hypotonia and hyporeflexia of both upper and lower limbs. Brain computed tomography, magnetic resonance imaging and lumbar puncture were normal. Laboratory investigations revealed severe hypokalemia, renal failure, liver impairment, rabdomyolysis, metabolic alkalos is, and low plasma renin and aldosterone levels. Continuous potassium replacement led to complete clinical resolution. A detailed history revealed chronic intake of 250 g/day black liquorice. Hypokalaemic muscle weakness ...
Source: High Blood Pressure and Cardiovascular Prevention - October 8, 2018 Category: Cardiology Source Type: research

Effects on Cardiovascular Risk Scores and Vascular Age After Aerobic Exercise and Nutritional Intervention in Sedentary and Overweight/Obese Adults with Primary Hypertension: The EXERDIET-HTA Randomized Trial Study
ConclusionsThe improvement in CVR factors after 16-week lifestyle changes reduced the risk of suffering a cardiovascular event in overweight/obese adults with HTN through the FRS estimation tool, but not with the ASCVD score. The risk score algorithms could underestimate CVR in women. In contrast, VA could be a useful and easier tool in the management of individuals with CVR factors. (Source: High Blood Pressure and Cardiovascular Prevention)
Source: High Blood Pressure and Cardiovascular Prevention - September 24, 2018 Category: Cardiology Source Type: research