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Total 2301 results found since Jan 2013.

CDH13 Genetic Polymorphisms, Adiponectin and Ischemic Stroke: a Chinese Family-based Sib-pair Study
Conclusion CDH13 genetic polymorphisms are associated with adiponectin levels and ischemic stroke. An interaction is found between CDH13 SNP and diabetes for ischemic stroke.
Source: Biomedical and Environmental Sciences - March 3, 2017 Category: Biomedical Science Source Type: research

Pivotal neuroinflammatory and therapeutic role of high mobility group box 1 in ischemic stroke.
Abstract Stroke is a major cause of mortality and disability worldwide. Stroke is a frequent and severe neurovascular disorder. The main cause of stroke is atherosclerosis, and the most common risk factor for atherosclerosis is hypertension. Therefore, prevention and treatment of stroke are crucial issues in humans. High mobility group box 1 (HMGB1) is non-histone nuclear protein that is currently one of the crucial pro-inflammatory alarmin in ischemic stroke (IS). It is instantly released from necrotic cells in the ischemic core and activates an early inflammatory response. HMGB1 may signal via its putative recep...
Source: Bioscience Reports - October 20, 2017 Category: Biomedical Science Authors: Richard SA, Sackey M, Su Z, Xu H Tags: Biosci Rep Source Type: research

Combined Effects of Family History of Cardiovascular Disease and Serum C-reactive Protein Level on the Risk of Stroke: A 9.2-year Prospective Study among Mongolians in China.
CONCLUSION: Participants with both a family history of CVD and high CRP levels had the highest stroke incidence, suggesting that high CRP levels may increase stroke risk, especially of ischemic stroke, among individuals with a family history of CVD. PMID: 29081337 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - September 1, 2017 Category: Biomedical Science Authors: Zhu ZB, Huangfu XF, Zhong CK, Zhou YP, Tian YF, Buren B, Xu T, Wang AL, Li HM, Zhang MZ, Zhang YH Tags: Biomed Environ Sci Source Type: research

Combined Effects of A Body Shape Index and Serum C-reactive Protein on Ischemic Stroke Incidence among Mongolians in China.
CONCLUSION: We found that participants with simultaneously high ABSI and high CRP levels had the highest risk of ischemic stroke in the Mongolian population. Our findings suggest that the combination of high ABSI and high CRP levels may increase the risk of ischemic stroke. PMID: 30987691 [PubMed - in process]
Source: Biomedical and Environmental Sciences : BES - February 28, 2019 Category: Biomedical Science Authors: Wang GL, Zhang R, Zhou YT, Wang AL, Xu T, Zhang MZ, Li HM, Zhang YH Tags: Biomed Environ Sci Source Type: research

Association of DIAPH1 gene polymorphisms with ischemic stroke.
Abstract DIAPH1 is a formin protein involved in actin polymerization with important roles in vascular remodeling and thrombosis. To investigate potential associations of DIAPH1 single-nucleotide polymorphisms (SNPs) with hypertension and stroke, 2,012 patients with hypertension and 2,210 controls, 2,966 stroke cases [2,212 ischemic stroke (IS), 754 hemorrhagic stroke (HS)] and 2,590 controls were enrolled respectively in the case-control study. A total of 4,098 individual were included in the cohort study. DIAPH1 mRNA expression was compared between 66 IS [43 small artery occlusion (SAO) and 23 large-artery athero...
Source: Aging - January 2, 2020 Category: Biomedical Science Authors: Ren Z, Chen X, Tang W, Li J, Yang S, Chen Y, Zhao X, Zong H, Liu C, Shen C Tags: Aging (Albany NY) Source Type: research

Atrial fibrillation risk factors in patients with ischemic stroke.
Conclusions: Our study demonstrates a need for thorough and systematic monitoring of post-ischemic stroke patients in whom AF has not been detected and who display other important risk factors. Regardless of the stroke, these factors may be responsible for development of AF. PMID: 33488851 [PubMed]
Source: Archives of Medical Science - January 27, 2021 Category: Biomedical Science Tags: Arch Med Sci Source Type: research

A novel risk model to predict first-ever ischemic stroke in heart failure with reduced ejection fraction.
Abstract Patients with heart failure are at increased risk for ischemic stroke. We aim to develop a more accurate stroke risk prediction tools identify high-risk patients with heart failure with reduced ejection fraction (HFrEF). Patient data were extracted retrospectively from the electronic medical database between January 2009 and February 2019. Univariate and multivariate Cox regression analysis were performed to identify independent predictors, which were utilized to construct a nomogram for predicting ischemic stroke. AUROC analysis was used to compare the prognostic value between the new risk score and CHAD...
Source: Aging - February 1, 2021 Category: Biomedical Science Authors: Zhou X, Yu L, Hu W, Shi R, Ji Y, Zhou C, Xue C, Yu G, Huang W, Shan P Tags: Aging (Albany NY) Source Type: research

The copy number variation and stroke (CaNVAS) risk and outcome study
ConclusionThe CaNVAS study will cost-effectively leverage the numerous advantages of using existing case-control data sets, exploring the relationships between CNV and IS and its subtypes, and outcome at 3 months, in both men and women, in those of African and European-Caucasian descent, this, across the entire adult-age spectrum.
Source: PLoS One - April 19, 2021 Category: Biomedical Science Authors: John W. Cole Source Type: research

Role of dyslipidemia in ischemic stroke patients treated in the telestroke network
CONCLUSION: Demographic and clinical risk factors among the dysplipidemic ischemic stroke population in the telestroke network were not associated with worsening neurologic functions.PMID:33940526 | DOI:10.1016/j.advms.2021.04.003
Source: Advances in Medical Sciences - May 3, 2021 Category: Biomedical Science Authors: Leanne Brechtel Nicolas Poupore Margaret Monroe Krista Knisley Carolyn Sanders Camron Edrissi Chase Rathfoot Thomas I Nathaniel Source Type: research