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Specialty: Biomedical Science
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Total 2301 results found since Jan 2013.
Emergency Cervical Carotid Artery Stenting After Intravenous Thrombolysis in Patients With Hyperacute Ischemic Stroke
CONCLUSION: We showed that emergent carotid artery stenting after IV rtPA therapy for hyperacute stroke caused by atherosclerotic proximal ICA steno-occlusion was feasible and safe.PMID:35578588 | DOI:10.3346/jkms.2022.37.e156
Source: Journal of Korean Medical Science - May 17, 2022 Category: Biomedical Science Authors: Doo Hyuk Kwon Seong Hwa Jang Hyungjong Park Sung-Il Sohn Jeong-Ho Hong Source Type: research
Surface electromyographic activity of trunk muscles during trunk control exercises for people after stroke; effect of a mobile and stable seat for rehabilitation
by Michelle C. Haas, Bettina B. Sommer, Samuel Karrer, Matthias J örger, Eveline S. Graf, Martin Huber, Daniel Baumgartner, Jens Bansi, Jan Kool, Christoph M. Bauer
The aim of this study was to explore differences in trunk muscle activity on a stable and mobile seat for people after stroke and healthy participants. Trunk control exercises are known to have a beneficial effect on trunk control, balance, and mobility after stroke. The effect of such exercises c ould be enhanced by the use of a mobile seat to provide further training stimuli. However, little research on the musculoskeletal effects of trunk training on mobil...
Source: PLoS One - July 29, 2022 Category: Biomedical Science Authors: Michelle C. Haas Source Type: research
External validation and extension of the Early Prediction of Functional Outcome after Stroke (EPOS) prediction model for upper limb outcome 3 months after stroke
ConclusionsThe EPOS model was successfully validated in first-ever stroke patients with mild-to-moderate neurological impairments, who were independent before their stroke. Now, its impact on clinical practice should be investigated in this population. Testing the model ’s performance in severe (recurrent) strokes and stratification of patients using the ARAT 32-point cut-off is required to enhance the model’s generalizability and potential clinical impact.
Source: PLoS One - August 8, 2022 Category: Biomedical Science Authors: Janne M. Veerbeek Source Type: research
Regulation of microglial activation in stroke in aged mice: a translational study
In this study, aged (18-20-month-old), microglial IRF5 or IRF4 conditional knockout (CKO) mice were subjected to a 60-min middle cerebral artery occlusion (MCAO). Stroke outcomes were quantified at 3d after MCAO. Flow cytometry and ELISA were performed to evaluate microglial activation and immune responses. We found aged microglia express higher levels of IRF5 and lower levels of IRF4 than young microglia after stroke. IRF5 CKO aged mice had improved stroke outcomes; whereas worse outcomes were seen in IRF4 CKO vs. their flox controls. IRF5 CKO aged microglia had significantly lower levels of IL-1β and CD68 than controls;...
Source: Aging - August 13, 2022 Category: Biomedical Science Authors: Conelius Ngwa Abdullah Al Mamun Shaohua Qi Romana Sharmeen Yan Xu Fudong Liu Source Type: research
Risk of Subsequent Events in Patients With Minor Ischemic Stroke or High-Risk Transient Ischemic Attack
This study aimed to present the prognosis after minor acute ischemic stroke (AIS) or transient ischemic attack (TIA), using a definition of subsequent stroke in accordance with recent clinical trials. In total, 9,506 patients with minor AIS (National Institutes of Health Stroke Scale ≤ 5) or high-risk TIA (acute lesions or ≥ 50% cerebral artery steno-occlusion) admitted between November 2010 and October 2013 were included. The primary outcome was the composite of stroke (progression of initial event or a subsequent event) and all-cause mortality. The cumulative incidence of stroke or death was 11.2% at 1 month, 13.3% a...
Source: Journal of Korean Medical Science - August 23, 2022 Category: Biomedical Science Authors: Keon-Joo Lee Dong Woo Shin Hong-Kyun Park Beom Joon Kim Jong-Moo Park Kyusik Kang Tai Hwan Park Kyung Bok Lee Keun-Sik Hong Yong-Jin Cho Dong-Eog Kim Wi-Sun Ryu Byung-Chul Lee Kyung-Ho Yu Mi-Sun Oh Soo Joo Lee Jae Guk Kim Jun Lee Jae-Kwan Cha Dae-Hyun Kim Source Type: research
