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Specialty: Cancer & Oncology
Condition: Obesity

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Total 109 results found since Jan 2013.

Baseline cardiovascular comorbidities, and the influence on cancer treatment decision-making in women with breast cancer
CONCLUSION: While recent guidelines recommend routine assessment of cardiovascular comorbidities in cancer patients prior to initiation of anticancer therapies, this study highlights the prevailing gap in knowledge on how such data may be used to optimise cancer treatment decision-making.PMID:34824616 | PMC:PMC8580595 | DOI:10.3332/ecancer.2021.1293
Source: Ecancermedicalscience - November 26, 2021 Category: Cancer & Oncology Authors: Shridevi Subramaniam Yek-Ching Kong Hafizah Zaharah Cuno S P M Uiterwaal Andrea Richard Nur Aishah Taib Azura Deniel Kok-Han Chee Ros Suzanna Bustamam Mee-Hoong See Alan Fong Cheng-Har Yip Nirmala Bhoo-Pathy Source Type: research

Causes and Consequences of Polycystic Ovary Syndrome: Insights from Mendelian Randomization
CONCLUSIONS: The accumulation of genome-wide association studies in PCOS has enabled multiple MR analyses identifying factors that may cause PCOS or be caused by PCOS. This knowledge will be critical to future development of measures to prevent PCOS in girls at risk as well as prevent complications in those who have PCOS.PMID:34669940 | DOI:10.1210/clinem/dgab757
Source: Clinical Genitourinary Cancer - October 20, 2021 Category: Cancer & Oncology Authors: Tiantian Zhu Mark O Goodarzi Source Type: research

Cancers, Vol. 13, Pages 3368: Physical Comorbidities and Depression in Recent and Long-Term Adult Cancer Survivors: NHANES 2007 –2018
Cancers, Vol. 13, Pages 3368: Physical Comorbidities and Depression in Recent and Long-Term Adult Cancer Survivors: NHANES 2007–2018 Cancers doi: 10.3390/cancers13133368 Authors: Dafina Petrova Andrés Catena Miguel Rodríguez-Barranco Daniel Redondo-Sánchez Eloísa Bayo-Lozano Rocio Garcia-Retamero José-Juan Jiménez-Moleón María-José Sánchez Many adult cancer patients present one or more physical comorbidities. Besides interfering with treatment and prognosis, physical comorbidities could also increase the already heightened psychological risk of cancer patients. To test this possibility, we...
Source: Cancers - July 5, 2021 Category: Cancer & Oncology Authors: Dafina Petrova Andr és Catena Miguel Rodr íguez-Barranco Daniel Redondo-S ánchez Elo ísa Bayo-Lozano Rocio Garcia-Retamero Jos é-Juan Jiménez-Moleón Mar ía-José Sánchez Tags: Article Source Type: research

Association between physical activity and subsequent cardiovascular disease among 5-year breast cancer survivors
ConclusionsThe study showed that even small amounts of PA may be beneficial in potentially decreasing the risk of CVD, CHD, and stroke in breast cancer survivors. Our result will be useful to prescribe and delivery exercise among long-term breast cancer survivors.
Source: Breast Cancer Research and Treatment - February 18, 2021 Category: Cancer & Oncology Source Type: research

Impact of the preoperative body mass index on the postoperative outcomes in patients with completely resected non-small cell lung cancer: A retrospective analysis of 16,503 cases in a Japanese Lung Cancer Registry Study
Obesity is responsible for multiple chronic diseases, including type 2 diabetes, hypertension, coronary artery disease, stroke, and several types of cancer [1]. The body mass index (BMI) —as an easy-to obtain, acceptable proxy for thinness and fatness—has been found to be associated with health risk and death in many populations. According to the World Health Organization definition, the normal range of BMI is defined as 18.5 to
Source: Lung Cancer - September 18, 2020 Category: Cancer & Oncology Authors: Koichi Fukumoto, Shoichi Mori, Yasushi Shintani, Jiro Okami, Hiroyuki Ito, Takashi Ohtsuka, Shinichi Toyooka, Takeshi Mori, Shun-ichi Watanabe, Hisao Asamura, Masayuki Chida, Hiroshi Date, Shunsuke Endo, Takeshi Nagayasu, Ryoichi Nakanishi, Etsuo Miyaoka, Source Type: research

Cancers, Vol. 12, Pages 1695: Association of Allostatic Load with All-Cause and Cancer Mortality by Race and Body Mass Index in the REGARDS Cohort
In conclusion, a higher baseline AL score was associated with increased risk ofall-cause and cancer-specific mortality among both Black and White participants. Targetedinterventions to patient groups with higher AL scores, regardless of race, may be beneficial as astrategy to reduce all-cause and cancer-specific mortality.
Source: Cancers - June 25, 2020 Category: Cancer & Oncology Authors: Akinyemiju Wilson Deveaux Aslibekyan Cushman Gilchrist Safford Judd Howard Tags: Article Source Type: research

Cancers, Vol. 12, Pages 1695: Association of Allostatic Load with All-Cause and Cancer Mortality by Race and Body Mass Index in the REGARDS Cohort
In conclusion, a higher baseline AL score was associated with increased risk of all-cause and cancer-specific mortality among both Black and White participants. Targeted interventions to patient groups with higher AL scores, regardless of race, may be beneficial as a strategy to reduce all-cause and cancer-specific mortality.
Source: Cancers - June 25, 2020 Category: Cancer & Oncology Authors: Tomi Akinyemiju Lauren E Wilson April Deveaux Stella Aslibekyan Mary Cushman Susan Gilchrist Monika Safford Suzanne Judd Virginia Howard Tags: Article Source Type: research

NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies. (GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research

Prevalence and Predictors of Current and Former Tobacco Use among Older Adults in Indonesia
Conclusions: A high rate of current tobacco use and low rate of former tobacco use was found, particularly among men. The identified risk factors may help to better target this vulnerable population with tobacco cessation programmes. PMID: 30803198 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - February 27, 2019 Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research

Pre-diagnostic biomarkers of metabolic dysregulation and cancer mortality.
CONCLUSIONS: Leptin is involved in long-term regulation of energy balance, while resistin is involved in chronic inflammation and LDL production. These findings highlight the biological mechanisms linking metabolic dysregulation with cancer mortality, and the influence of resistin on cancer mortality only among Blacks suggests that this hormone may be a useful biomarker of racial differences in cancer mortality that deserves further study. IMPACT: Our observed increased risk of cancer mortality associated with higher serum resistin levels among Blacks suggests that if validated in larger cohorts, clinical strategies fo...
Source: Oncotarget - April 19, 2018 Category: Cancer & Oncology Tags: Oncotarget Source Type: research

The Impact of Obesity on Breast Cancer
AbstractThe rates of obesity are increasing worldwide and this condition is now recognized as a leading preventable cause of cancer. Several diseases are directly related to obesity, including diabetes, hypertension, atherosclerosis, stroke, musculoskeletal disorders, and a diverse range of malignances —such as breast cancer. Obesity is associated with an increased risk of postmenopausal estrogen receptor-positive breast cancer and worse cancer-related outcomes for all breast tumor subtypes. Several mechanisms have been proposed to contribute to the obesity-cancer link, including high levels of circulating and local estr...
Source: Current Oncology Reports - April 11, 2018 Category: Cancer & Oncology Source Type: research

Cardiovascular Risk Markers and Major Adverse Cardiovascular Events in Psoriatic Arthritis Patients.
CONCLUSION: Psoriatic arthritis appeared significantly associated with subclinical atherosclerosis and endothelial dysfunction and, in turn, with an increased cardiovascular risk. Thus, patients with psoriatic arthritis may benefit from a periodic assessment of surrogate markers of cardiovascular risk. This could help to establish more specific cardiovascular prevention strategies for these patients. PMID: 29542417 [PubMed - as supplied by publisher]
Source: Reviews on Recent Clinical Trials - March 13, 2018 Category: Cancer & Oncology Authors: Caso F, Tasso M, Ambrosino P, Nicola M, Di Minno D, Lupoli R, Criscuolo L, Caso P, Ursini F, Puente AD, Scarpa R, Costa L, Peluso R Tags: Rev Recent Clin Trials Source Type: research