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Abstract 5267: Comorbidity and cause of death in patients with chronic lymphocytic leukemia (CLL)
Conclusions. Despite the advanced age at CLL diagnosis, the frequent presence of comorbidities, and the indolent nature of the disease, CLL progression is the ultimate cause of death in 51% of newly diagnosed CLL patients, with an additional 26% dying of causes potentially related to CLL, such as infections and second cancers. The influence of comorbidities and other clinical factors at diagnosis (e.g. smoking, Charlson Comorbidity Index) on survival and ultimate cause of death are being abstracted, and will be presented at the meeting.Citation Format: Paolo Strati, Kari Chaffe, Sara Achenbach, Timothy Call, Neil Kay, Jame...
Source: Cancer Research - August 2, 2015 Category: Cancer & Oncology Authors: Strati, P., Chaffe, K., Achenbach, S., Call, T., Kay, N., Cerhan, J., Slager, S., Shanafelt, T. Tags: Clinical Research (Excluding Clinical Trials) Source Type: research

Treatment and survival of non-alcoholic steatohepatitis associated hepatocellular carcinoma
Background: The incidence of non-alcoholic steatohepatitis (NASH) is increasing worldwide and a poorly defined subset of patients develops end-stage liver disease and hepatocellular carcinoma (HCC). Differences in the biological behaviour, tumour characteristics, associated risk factors, treatment outcomes and overall survival of patients with NASH-HCC remain poorly defined. The aim of this study was to determine and analyze these differences in a large clinical cohort to guide treatment decisions. Methods: 1119 patients with HCC treated in an 11 year period at the University Medical Centre of the Johannes Gutenberg Unive...
Source: BMC Cancer - April 1, 2015 Category: Cancer & Oncology Authors: Arndt WeinmannYvonne AltSandra KochCarina NellesChristoph DüberHauke LangGerd OttoTim ZimmermannJens MarquardtPeter GalleMarcus WörnsJörn Schattenberg Source Type: research

Influence of Conventional Cardiovascular Risk Factors and Lifestyle Characteristics on Cardiovascular Disease After Hematopoietic Cell Transplantation Health Services and Outcomes
Conclusion Attention of clinicians to conventional cardiovascular risk factors and modifiable lifestyle characteristics offers hope of reducing serious cardiovascular morbidity after HCT.
Source: Journal of Clinical Oncology - January 17, 2014 Category: Cancer & Oncology Authors: Chow, Baker, Lee, Flowers, Cushing-Haugen, Inamoto, Khera, Leisenring, Syrjala, Martin Tags: Leukemia, Lymphoma, Myeloma, Outcomes Research Health Services and Outcomes Source Type: research

Lowering 3 risk factors could cut obesity-related risk of heart disease by more than half
(Harvard School of Public Health) Controlling blood pressure, serum cholesterol, and blood glucose may substantially reduce the risk of heart disease and stroke associated with being overweight or obese.
Source: EurekAlert! - Cancer - November 21, 2013 Category: Cancer & Oncology Source Type: news

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