Filtered By:
Specialty: Neurology
Cancer: Brain Cancers

This page shows you your search results in order of date. This is page number 15.

Order by Relevance | Date

Total 371 results found since Jan 2013.

Stroke like migraine attacks after radiation therapy (SMART) syndrome a case series of three patients (P6.179)
Conclusions:Our patients represent the first case series of SMART syndrome in a single institution. Our cases share similarities to the prior reports in the literature and highlights the clinical and MRI triad of acute onset headaches, neurological deficits and MRI findings of transient contrast enhancement of the cortex with white matter sparing in a previous radiation field.Disclosure: Dr. rauf has nothing to disclose. Dr. Boulter has nothing to disclose. Dr. Imitola has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Rauf, Y., Boulter, D., Imitola, J. Tags: Neurologic Complications of Cancer Source Type: research

Recurrent Stroke after Silent Brain Infarction in Patients with Primary Brain Tumors (S51.007)
Conclusions:The short-term risk of recurrent ischemic stroke in patients with PBTs was substantial and the risk was comparable whether the stroke was silent or symptomatic.Study Supported by: Babak Navi was supported by grants from the NINDS (K23NS091395) and the Florence Gould Endowment for Discovery in Stroke. Hooman Kamel was supported by grants from the NINDS (K23NS082367) and the Michael Goldberg Stroke Research Fund.Disclosure: Dr. Parikh has nothing to disclose. Dr. Burch has nothing to disclose. Dr. Kamel has received personal compensation for activities with Genentech as a speaker. Dr. Kamel has received personal ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Parikh, N., Burch, J., Kamel, H., DeAngelis, L., Navi, B. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke Prevention and Translation Source Type: research

Risk factors for developing epilepsy in a U.S. commercially insured pediatric population (P4.328)
Conclusions:Epilepsy incidence was highest in the youngest ages. The most significant risk factors for newly diagnosed epilepsy were neonatal seizures, central nervous system infection, and childhood static encephalopathy, although most pediatric epilepsy patients no recorded putative risk factors.Study Supported by: Children’s Healthcare of Atlanta Research Grant as a part of the Goizueta Foundation Project.Disclosure: Dr. Oh has nothing to disclose. Dr. Thurman has received personal compensation for activities with UCB as a consultant. Dr. Thurman has received research support from UCB. Dr. Kim has received researc...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Oh, A., Thurman, D., Kim, H. Tags: Neuroepidemiology Source Type: research

A Rare Neurological Complication of Waldenstroms Macroglobulinemia (P5.183)
Conclusions:Diagnostic approach to bilateral FNP should evaluate for: traumatic (skull fractures), infectious (classically Lyme disease), metabolic (diabetes), autoimmune (sarcoidosis, Guillain-Barré syndrome), congenital (Moebius syndrome) and neoplastic (brainstem tumors) entities. WM is a rare cause, a condition due to low-grade B cell lymphoma where lymphoplasmacytoid cells infiltrate different tissues and secrete monoclonal IgM. Peripheral neuropathy develops in 15–30% of the cases, usually a chronic, progressive, symmetric, predominantly distal polyneuropathy. Facial nerve impairment is unusual, caused b...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Acosta, G. T., Gadhia, R., Leslie-Mazwi, T. Tags: Neuro-oncology: Brain and CNS Metastases Source Type: research

Dynamic interaction between EEG and ICP: a pilot study based on wavelet coherence (P6.064)
Conclusions:Wavelet analysis used in this feasibility study is a promising method to study the dynamic interaction between ICP and EEG changes. Further prospective study focusing on specific population is needed to understand the significance of the coherence between ICP and EEG. Neurovascular coupling described in the literature maybe related to our observed results.Disclosure: Dr. Perez has nothing to disclose. Dr. Tian has nothing to disclose. Dr. Olson has nothing to disclose. Dr. Aiyagari has nothing to disclose. Dr. Stutzman has nothing to disclose. Dr. Griffin has nothing to disclose. Dr. Kalia has nothing to disclo...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Perez, C., Tian, F., Olson, D., Aiyagari, V., Stutzman, S., Griffin, J., Kalia, J., Zhang, R., Ding, K. Tags: Neurocritical Care: Intracranial Pressure Source Type: research

Novel quantitative imaging markers for understanding cognitive reserve in subdural hematoma (SDH) patients (P5.037)
Conclusions:Quantitative imaging can be used to predict functional outcomes in patients with intracranial hemorrhages. As we continue enrollment we hope to generate meaningful novel markers of cognitive reserve and recovery in patients with intracranial hemorrhages and other pathologies like acute stroke and brain tumors.Disclosure: Dr. Dangayach has nothing to disclose. Dr. Nicol has nothing to disclose. Dr. Sobotka has nothing to disclose. Dr. Griffiths has nothing to disclose. Dr. Costa has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Mayer has received personal compensation for activities with Bard Medical...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Dangayach, N., Nicol, K., Sobotka, S., Griffiths, S., Costa, A., Lee, J., Mayer, S., Frontera, J., Gordon, E., Bederson, J. Tags: Neurocritical Care: Coma/Mental Status Source Type: research

Recurrent Stroke Due to Metastatic Pulmonary Tumor Emboli as an Important Clinical Entity
We present an autopsy case of repetitive stroke due to tumor emboli, indistinguishable from thromboembolism with a hypercoagulable state in its clinical course. A 72-year-old man diagnosed with stage IVA oropharyngeal squamous cell carcinoma received chemoradiotherapy. Follow-up imaging revealed mediastinal lymph nodes and pulmonary metastasis. One year later, the patient experienced right arm weakness, and brain magnetic resonance imaging showed acute ischemic lesions in multiple vascular territories.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2017 Category: Neurology Authors: Junji Takasugi, Manabu Sakaguchi, Naoki Oyama, Yasufumi Gon, Yasukazu Terasaki, Tsutomu Sasaki, Susumu Nakahara, Kenji Ohshima, Yumiko Hori, Eiichi Morii, Hideki Mochizuki Tags: Case Studies Source Type: research

Calcified Amorphous Tumor Causing Shower Embolism to the Brain: A Case Report with Serial Echocardiographic and Neuroradiologic Images and a Review of the Literature
An 89-year-old woman with chronic atrial fibrillation, hypertension, chronic heart failure, and dementia was admitted to our hospital due to multiple small cerebral and cerebellar infarctions. Transthoracic echocardiogram revealed a floating calcified mass lesion arising from the endocardium of the posterior portion of the mitral annulus with mitral annular calcification. Furthermore, the mass had a heterogeneity of the echogenicity. The mass was diagnosed as a calcified amorphous tumor based on specific echocardiographic features.
Source: Journal of Stroke and Cerebrovascular Diseases - March 17, 2017 Category: Neurology Authors: Takaomi Singu, Yuichiro Inatomi, Toshiro Yonehara, Yukio Ando Tags: Case Studies Source Type: research

Prevalence of epilepsy/seizures as a comorbidity of neurologic disorders in nursing homes
Conclusions: The prevalence of epi/sz in the elderly nursing home population is >7-fold higher compared to community-dwelling elderly and is 7 to 30 times higher among those with certain comorbid neurologic conditions. Demographics and clinical characteristics had weaker associations with epi/sz prevalence.
Source: Neurology - February 19, 2017 Category: Neurology Authors: Birnbaum, A. K., Leppik, I. E., Svensden, K., Eberly, L. E. Tags: All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, Brain trauma, Prevalence studies, All Epilepsy/Seizures ARTICLE Source Type: research

Human Muse Cells Reconstruct Neuronal Circuitry in Subacute Lacunar Stroke Model Basic Sciences
Conclusions—Transplantation at the delayed subacute phase showed muse cells differentiated into neural cells, facilitated neural reconstruction, improved functions, and displayed solid safety outcomes over prolonged graft maturation period, indicating their therapeutic potential for lacunar stroke.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Hiroki Uchida, Kuniyasu Niizuma, Yoshihiro Kushida, Shohei Wakao, Teiji Tominaga, Cesario V. Borlongan, Mari Dezawa Tags: Cell Therapy, Stem Cells, Translational Studies, Ischemic Stroke Original Contributions Source Type: research

Pinocembrin Protects Hemorrhagic Brain Primarily by Inhibiting Toll-like Receptor 4 and Reducing M1 Phenotype Microglia
In this study, we examined the efficacy of pinocembrin in an ICH model, and further examined its effect on microglial activation and polarization. In vivo, pinocembrin dose-dependently reduced lesion volume by ∼47.5% and reduced neurologic deficits of mice at 72 h after collagenase-induced ICH. The optimal dose of pinocembrin (5 mg/kg) suppressed microglial activation as evidenced by decreases in CD68-positive microglia and reduced proinflammatory cytokines tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6. Pinocembrin also reduced the number of classically activated M1-like microglia without affecting M2-li...
Source: Brain, Behavior, and Immunity - December 20, 2016 Category: Neurology Source Type: research

Pinocembrin Protects Hemorrhagic Brain Primarily by Inhibiting Toll-like Receptor 4 and Reducing M1 Phenotype Microglia.
In this study, we examined the efficacy of pinocembrin in an ICH model, and further examined its effect on microglial activation and polarization. In vivo, pinocembrin dose-dependently reduced lesion volume by ∼47.5% and reduced neurologic deficits of mice at 72 h after collagenase-induced ICH. The optimal dose of pinocembrin (5 mg/kg) suppressed microglial activation as evidenced by decreases in CD68-positive microglia and reduced proinflammatory cytokines tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6. Pinocembrin also reduced the number of classically activated M1-like microglia without affecting M2-li...
Source: Brain, Behavior, and Immunity - December 18, 2016 Category: Neurology Authors: Lan X, Han X, Li Q, Li Q, Gao Y, Cheng T, Wan J, Zhu W, Wang J Tags: Brain Behav Immun Source Type: research

Direct Conversion of Somatic Cells into Induced Neurons
AbstractThe progressive loss and degeneration of neurons in the central nervous system (CNS), as a result of traumas or diseases including Alzheimer ’s, Parkinson’s, Huntington’s disease, stroke, and traumatic injury to the brain and spinal cord, can usually have devastating effects on quality of life. The current strategies available for treatments are described including drug delivery, surgery, electrical stimulation, and cell-based tiss ue engineering approaches. However, apart from cell-based therapy, other attempts are limited in improving clinical outcomes. Recently, stem cell and neural stem cell (NSC) in part...
Source: Molecular Neurobiology - December 15, 2016 Category: Neurology Source Type: research

Homonymous hemianopia as the first sign of posterior cortical atrophy
Posterior cortical atrophy (PCA), also called Benson's syndrome, is a progressive neurodegenerative syndrome affecting visual cortical regions, with relative preservation of memory [1]. PCA can be a cause of visual field deficits [2], although rare when compared with other causes of homonymous hemianopia (HH) such as stroke (52% –70% of cases), traumatic brain injury (14%) and tumors (11%) [3]. The importance of detecting visual field disorders in the diagnosis of PCA has been first underlined by Tang-Way and colleagues [1] and confirmed later [4].
Source: Journal of the Neurological Sciences - December 12, 2016 Category: Neurology Authors: Christian Cordano, Alessandria Giulia, Leonardi Alessandro, Maria Cellerino, Bardia Nourbakhsh, Nobili Flavio, Bandini Fabio Tags: Letter to the Editor Source Type: research

Neuroimmune Crosstalk in CNS Disorders: The Histamine Connection.
Abstract The neuroimmune system represents a dense network of biochemical signals associated with neurotransmitters, neuropeptides, neurohormones, cytokines, chemokines, and growth factors synthesized in neurons, glial cells and immune cells, to maintain systemic homeostasis. Endogenous and/or exogenous, noxious stimuli in any tissue are captured by sensor cells to inform the brain; likewise, signals originating at the central nervous system (CNS) level are transmitted to peripheral immune effectors which react to central stimuli. This multidirectional information system makes it possible for the CNS to respond to...
Source: Epilepsy Curr - November 1, 2016 Category: Neurology Authors: Cacabelos R, Torrellas C, Fernández-Novoa L, Aliev G Tags: Curr Pharm Des Source Type: research