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Total 77 results found since Jan 2013.

Wake-Up Right-Sided Hemiparesis and Dysarthria in a Heavy Snorer.
Abstract CASE PRESENTATION: A 57-year-old man was referred to the ED for wake-up right-sided hemiparesis, hypoesthesia, dysarthria, and a National Institutes of Health Stroke Scale score of 7. Urgent CT brain scanning showed an ischemic lesion of the left temporal and insular lobes. The patient was admitted to the stroke unit, and acetylsalicylic acid 300 mg and low-molecular-weight heparin 6,000 IU were administered. PMID: 29307434 [PubMed - in process]
Source: Chest - January 1, 2018 Category: Respiratory Medicine Authors: Brunetti V, Ferilli MAN, Vollono C, Di Franco A, Della Marca G Tags: Chest Source Type: research

Clinical Importance of Temporal Bone Features for the Efficacy of Contrast-Enhanced Sonothrombolysis: a Retrospective Analysis of the NOR-SASS Trial
AbstractContrast-enhanced sonothrombolysis (CEST) seems to be a safe and promising treatment in acute ischemic stroke. It remains unknown if temporal bone features may influence the efficacy of CEST. We investigated the association between different temporal bone features on admission computed tomography (CT) scan and the outcome in acute ischemic stroke patients included in the randomized Norwegian Sonothrombolysis in Acute Stroke Study (NOR-SASS). Patients diagnosed as stroke mimics and those with infratentorial stroke or with incorrect insonation were excluded. We retrospectively assessed temporal bone heterogeneity (pr...
Source: Translational Stroke Research - November 8, 2017 Category: Neurology Source Type: research

Biomarkers can reveal traumatic brain injury, even when concussions don ’t show up on CAT scan
FINDINGSUCLA researchers have identified four biomarkers that could help doctors diagnose brain trauma and concussions through a simple blood test. The biomarkers are proteins, from brain cells called astrocytes, which are released instantly into the bloodstream when astrocytes ’ outer membranes rupture from blunt impact or whiplash trauma.BACKGROUNDMild traumatic brain injuries, also called concussions, often go undiagnosed, but they can lead to lasting neurological impairment, especially after repeated occurrences.Currently, doctors use CT scans or a standard scoring system to describe the level of consciousness in a p...
Source: UCLA Newsroom: Health Sciences - October 27, 2017 Category: Universities & Medical Training Source Type: news

NIH researchers uncover drain pipes in our brains
(NIH/National Institute of Neurological Disorders and Stroke) By scanning the brains of healthy volunteers, researchers at the National Institutes of Health saw the first, long-sought evidence that our brains may drain some waste out through lymphatic vessels, the body's sewer system. The results further suggest the vessels could act as a pipeline between the brain and the immune system.
Source: EurekAlert! - Medicine and Health - October 3, 2017 Category: International Medicine & Public Health Source Type: news

Factors associated with early dramatic recovery following successful recanalization of occluded artery by endovascular treatment in anterior circulation stroke
Publication date: Available online 3 October 2017 Source:Journal of Clinical Neuroscience Author(s): Dae-Hyun Kim, Hyun-Wook Nah, Hyun-Seok Park, Jae-Hyung Choi, Myung-Jin Kang, Jae-Kwan Cha Endovascular treatment (EVT) significantly increases the recanalization rate and improves functional outcomes in acute ischemic stroke. However, despite successful recanalization by EVT, some stroke patients demonstrate no early dramatic recovery (EDR). We assessed factors associated with EDR following recanalization by EVT. We included subjects with anterior circulation stroke treated with EVT who met the following criteria: Thrombol...
Source: Journal of Clinical Neuroscience - October 3, 2017 Category: Neuroscience Source Type: research

Predictors for Cerebral Edema in Acute Ischemic Stroke Treated With Intravenous Thrombolysis Clinical Sciences
Background and Purpose—Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction. We aimed to determine which baseline clinical and radiological parameters predict development of CED in patients treated with intravenous thrombolysis.Methods—We used an image-based classification of CED with 3 degrees of severity (less severe CED 1 and most severe CED 3) on postintravenous thrombolysis imaging scans. We extracted data from 42 187 patients recorded in the SITS International Register (Safe Implementation of Trea...
Source: Stroke - August 28, 2017 Category: Neurology Authors: Magnus Thoren, Elsa Azevedo, Jesse Dawson, Jose A. Egido, Anne Falcou, Gary A. Ford, Staffan Holmin, Robert Mikulik, Jyrki Ollikainen, Nils Wahlgren, Niaz Ahmed Tags: Risk Factors, Imaging, Blood-Brain Barrier, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

PreHospital Ambulance Stroke Test - pilot study of a novel stroke test
There is a need for a prehospital stroke test that in addition to high sensitivity for stroke, also is able to communicate stroke severity similar to the National Institute of Health Stroke Scale (NIHSS).
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - April 11, 2017 Category: Emergency Medicine Authors: Gunnar Andsberg, Magnus Esbj örnsson, Arne Olofsson, Arne Lindgren, Bo Norrving and Mia von Euler Source Type: research

Periventricular White Matter Lesions as a Prognostic Factor of Swallowing Function in Older Patients with Mild Stroke
AbstractOlder patients with stroke have poor functional prognosis compared to younger patients. Patients with stroke who have severe white matter (WM) lesions have been reported to have poor functional prognosis such as cognitive dysfunction, increased propensity for falling, and gait and balance problems. The aim of this study was to determine whether WM lesions exert negative effects on swallowing function in older patients with mild stroke. We conducted a retrospective analysis of 63 patients aged  >65  years who had a National Institutes of Health Stroke Scale score ≤5 and who underwent videofluoroscopic swallo...
Source: Dysphagia - March 27, 2017 Category: Speech Therapy Source Type: research

Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial
This study is registered with ClinicalTrials.gov, number NCT01436487. Findings The study was done between Oct 24, 2011, and Dec 7, 2015. After safety assessments in eight patients in group 1, 129 patients were randomly assigned (67 to receive multipotent adult progenitor cells and 62 to receive placebo) in groups 2 and 3 (1200 million cells). The ITT populations consisted of 65 patients who received multipotent adult progenitor cells and 61 patients who received placebo. There were no dose-limiting toxicity events in either group. There were no infusional or allergic reactions and no difference in treatment-emergent advers...
Source: The Lancet Neurology - March 17, 2017 Category: Neurology Source Type: research

7 medtech stories we missed this week: Feb. 24, 2017
[Photo from unsplash.com]Several companies made distribution deals this week, while others received approval for their products. Here are 7 medtech stories we missed this week but were still worth mentioning. 1. Israel OKs E-Qure’s BST device for chronic wounds E-Qure Corp. announced this week that it received marketing approval for its Bio-electrical Signal Therapy Device (BST Device) from the Israeli Ministry of Health, according to a Feb. 24 news release. BST is an electrotherapeutic method for treating chronic wounds. E-Qure will begin marketing its device in Israel by activating a signed distribution agreement with...
Source: Mass Device - February 24, 2017 Category: Medical Equipment Authors: Danielle Kirsh Tags: Electronic Medical Records Imaging Mergers & Acquisitions mHealth (Mobile Health) Regulatory/Clearance Align Technology Clarius Mobile Health Corin Group E-Qure Henry Schein Medical Nexstim Skyline Medical Source Type: news

Clinical Evaluation of the Patient With Acute Stroke
This article reviews the clinical evaluation of the patient with acute stroke, including key questions in the focused stroke history, important aspects of the National Institutes of Health Stroke Scale and focused neurologic examination, and the significance of the basic head CT scan in informing a timely treatment decision. Recent Findings: Advances in both stroke treatment and enhanced diagnostics support an evolving paradigm for acute stroke care, ranging from the prehospital setting to the rehabilitative setting. An international emphasis on best practice strategies promotes efficiency and standardization in stroke sy...
Source: CONTINUUM: Lifelong Learning in Neurology - February 1, 2017 Category: Neurology Tags: Review Articles Source Type: research

An assessment of the correlation between early postinfarction pyramidal tract Wallerian degeneration and nerve function recovery using diffusion tensor imaging.
This study aimed to evaluate the clinical significance of diffusion tensor imaging (DTI) in the early diagnosis of pyramidal tract Wallerian degeneration (WD) and assessment of neurological recovery following cerebral infarction. This study included 23 patients with acute cerebral infarction and 10 healthy adult controls. All participants underwent both magnetic resonance imaging (MRI) and DTI scans. DTI images were analyzed using the Functional MRI of the Brain Software Library to determine the regions of interest (ROI) and obtain the mean diffusivity (MD) and fractional anisotropy (FA) value for each ROI. The correlation...
Source: Genetics and Molecular Research - January 22, 2017 Category: Genetics & Stem Cells Authors: Guo AH, Hao FL, Liu LF, Wang BJ, Jiang XF Tags: Genet Mol Res Source Type: research

Cell therapy for cerebral hemorrhage: Five year follow-up report.
Authors: Chang Z, Mao G, Sun L, Ao Q, Gu Y, Liu Y Abstract The aim of the study was to examine treatment of cerebral hemorrhages with bone-marrow or human umbilical cord-derived mesenchymal stem cells (BMSCs or Hu-MSCs) and conventional surgical approaches, and determine and compare the effectiveness, feasibility, safety and reproducibility of each method. A retrospective analysis was performed on a cohort of cell-treated cerebral hemorrhage patients from October 1, 2007 to October 1, 2009. A total of 24 patients, all of whom received conventional surgical treatment, were classified as follows: i) The control group...
Source: Experimental and Therapeutic Medicine - January 20, 2017 Category: Journals (General) Tags: Exp Ther Med Source Type: research

Frequency and Predictors of Dysphagia in Patients With Recent Small Subcortical Infarcts Brief Report
Background and Purpose—Detailed data on the occurrence of swallowing dysfunction in patients with recent small subcortical infarcts (RSSI) in the context of cerebral small vessel disease are lacking. This prompted us to assess the frequency of and risk factors for dysphagia in RSSI patients.Methods—We identified all inpatients with magnetic resonance imaging–confirmed RSSI between January 2008 and February 2013. Demographic and clinical data were extracted from our stroke database, and magnetic resonance imaging scans were reviewed for morphological changes. Dysphagia was determined according to the Gugging Swallowin...
Source: Stroke - December 22, 2016 Category: Neurology Authors: Simon Fandler, Thomas Gattringer, Sebastian Eppinger, Kathrin Doppelhofer, Daniela Pinter, Kurt Niederkorn, Christian Enzinger, Joanna M. Wardlaw, Franz Fazekas Tags: Magnetic Resonance Imaging (MRI), Complications, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

Telestroke Imaging: A Review
ABSTRACT The use of telecommunications technology to provide the healthcare services, telemedicine, has been in use since the 1860s. The use of technology has ranged from providing medical care to far‐off places during wartimes to monitoring physiological measurements of astronauts in space. Since the 1990s, reports have been published on diagnoses of neurological diseases with the use of video links. Studies confirm that the neurological examinations, including the National Institutes of Health Stroke Scale, performed during teleneurology are dependable. The transfer of stroke patients in rural hospitals to bigger medic...
Source: Journal of Neuroimaging - November 1, 2016 Category: Radiology Authors: Fahad J. Laghari, Maxim D. Hammer Tags: Views and Reviews Source Type: research