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Periventricular White Matter Lesions as a Prognostic Factor of Swallowing Function in Older Patients with Mild Stroke

AbstractOlder patients with stroke have poor functional prognosis compared to younger patients. Patients with stroke who have severe white matter (WM) lesions have been reported to have poor functional prognosis such as cognitive dysfunction, increased propensity for falling, and gait and balance problems. The aim of this study was to determine whether WM lesions exert negative effects on swallowing function in older patients with mild stroke. We conducted a retrospective analysis of 63 patients aged  >65  years who had a National Institutes of Health Stroke Scale score ≤5 and who underwent videofluoroscopic swallowing examination after their first stroke. Linear regression analysis showed that oral transit time tended to increase as Fazekas grade increased (p = 0.003). In addition, inadequate mastication was related to the presence of lesions in the left hemisphere (p = 0.039). The presence of penetration could also be predicted by Fazekas grade (p = 0.015). Our findings suggest that WM lesions observed in brain magnetic resonance imaging scans can impact swallowing problems in older patients with mild stroke, regardless of initial stroke severity or other factors associated with lesion location. Accordingly, our data indicate that WM lesio ns are a predictive factor by which patients can be stratified into favorable or unfavorable outcomes with respect to dysphagia.
Source: Dysphagia - Category: Speech Therapy Source Type: research

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Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Publication date: 2017 Source:Handbook of Clinical Neurology, Volume 145 Author(s): Elna-Marie Larsson, Johan Wikström Neuroradiology with computed tomography (CT) and magnetic resonance imaging (MRI) is essential for the initial evaluation of patients with a clinical suspicion of brain and spine disorders. Morphologic imaging is required to obtain a probable diagnosis to support the treatment decisions in pre- and perinatal disorders, vascular diseases, traumatic injuries, metabolic disorders, epilepsy, infection/inflammation, neurodegenerative disorders, degenerative spinal disease, and tumors of the central nervou...
Source: Handbook of Clinical Neurology - Category: Neurology Source Type: research
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Source: Interventional Neuroradiology - Category: Radiology Tags: Interv Neuroradiol Source Type: research
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Source: European Neurology - Category: Neurology Source Type: research
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Source: NeuroImage: Clinical - Category: Radiology Source Type: research
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Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
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Source: Korean J Radiol - Category: Radiology Authors: Tags: Korean J Radiol Source Type: research
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Source: Stroke - Category: Neurology Authors: Tags: Magnetic Resonance Imaging (MRI), Nuclear Cardiology and PET, Moyamoya Original Contributions Source Type: research
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Source: Magnetic Resonance in Medicine - Category: Radiology Authors: Tags: Full Paper Source Type: research
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