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Condition: Heart Attack
Procedure: Coronary Artery Bypass Graft

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Total 1114 results found since Jan 2013.

Could intensive anti-hypertensive therapy produce the "J-curve effect" in patients with coronary artery disease and hypertension after revascularization?
CONCLUSIONS: For the patients who had CAD and hypertension, intensive anti-hypertensive therapy could produce the "J-curve effect" after revascularization with the optimal blood pressure (BP) range being 120-130/75-80 mmHg. PMID: 27097958 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - April 23, 2016 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Safety and efficacy of miniaturized extracorporeal circulation when compared with off-pump and conventional coronary artery bypass grafting: evidence synthesis from a comprehensive Bayesian-framework network meta-analysis of 134 randomized controlled trials involving 22 778 patients ADULT CARDIAC
CONCLUSIONS MECC and OPCAB both improve perioperative outcomes following coronary bypass surgery when compared with conventional CABG performed with extracorporeal circulation. MECC may represent an attractive compromise between OPCAB and CECC.
Source: European Journal of Cardio-Thoracic Surgery - April 28, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Kowalewski, M., Pawliszak, W., Raffa, G. M., Malvindi, P. G., Kowalkowska, M. E., Zaborowska, K., Kowalewski, J., Tarelli, G., Taggart, D. P., Anisimowicz, L. Tags: Molecular biology, History, Myocardial protection, Peripheral vascular, Transplantation - heart ADULT CARDIAC Source Type: research

Simultaneous Coronary Artery Bypass Grafting and Carotid Endarterectomy
Simultaneous coronary artery bypass grafting and carotid endarterectomy (CABG/CEA) includes two different surgical operations doing by two teams of operating surgeons during one anaesthetic support. Patients with concomitant coronary and carotid artery disease stay in group of high risk of perioperative acute stroke and myocardial infarction, and therefore conducting of simultaneous CABG/CEA can reduce the incidence of late myocardial infarction and postoperative stroke in this group of patients and can improve survival in the long-term period.
Source: Value in Health - April 30, 2016 Category: Global & Universal Authors: A Avdeyev, S, A Tabarov, B Sharip, L Zhanabekova, A Gizatullina Source Type: research

Cardiovascular highlights from non-cardiology journals
Pre-operative aspirin does not influence CABG outcomes Aspirin is a common therapy for risk reduction among patients with coronary artery disease. However, among patients undergoing coronary artery bypass surgery, the benefits of aspirin on the risk of myocardial infarction and stroke may be outweighed by perioperative bleeding risk. To address this question, the ATACAS trial randomized 2100 patients to either receive 100 mg aspirin daily or matching placebo for 4 days immediately prior to the operation with all patients resuming aspirin within 24 hours of their bypass surgery. The primary outcome was a composite of d...
Source: Heart - June 5, 2016 Category: Cardiology Authors: Bradley, S. M. Tags: Journal scan Source Type: research

The SYNTAX score is correlated with long-term outcomes of coronary artery bypass grafting for complex coronary artery lesions
CONCLUSIONS The SYNTAX score is correlated with long-term outcomes, in terms of MACCEs, after conventional CABG for complex coronary lesions and is prognostic of long-term outcomes of CABG for patients with complex lesions.
Source: Interactive CardioVascular and Thoracic Surgery - June 19, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Cho, Y., Shimura, S., Aki, A., Furuya, H., Okada, K., Ueda, T. Tags: Molecular biology, History Adult Cardiac Source Type: research

Hybrid Coronary Revascularization for the Treatment of Multivessel Coronary Artery Disease A Multicenter Observational Study
ConclusionsThese observational data from this first multicenter study of HCR suggest that there is no significant difference in MACCE rates over 12 months between patients treated with multivessel PCI or HCR, an emerging modality. A randomized trial with long-term outcomes is needed to definitively compare the effectiveness of these 2 revascularization strategies. (Hybrid Revascularization Observational Study; NCT01121263)
Source: Journal of the American College of Cardiology - July 18, 2016 Category: Cardiology Source Type: research

Bilateral Internal Thoracic Artery Configuration for Coronary Artery Bypass Surgery: A Prospective Randomized Trial Coronary Artery Disease
Conclusions— Three-year systematic angiographic follow-up revealed no significant difference in graft patency between the 2 BITA configurations. However, compared with in situ configuration, the use of BITA in a Y grafting configuration results in lower rates of major adverse cardiovascular and cerebrovascular events at 7 years. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01666366.
Source: Circulation: Cardiovascular Interventions - July 11, 2016 Category: Cardiology Authors: Glineur, D., Boodhwani, M., Hanet, C., de Kerchove, L., Navarra, E., Astarci, P., Noirhomme, P., El Khoury, G. Tags: Cardiovascular Surgery, Revascularization Coronary Artery Disease Source Type: research

Hybrid Coronary Revascularization for  the Treatment of Multivessel Coronary Artery Disease A Multicenter Observational Study
Conclusions These observational data from this first multicenter study of HCR suggest that there is no significant difference in MACCE rates over 12 months between patients treated with multivessel PCI or HCR, an emerging modality. A randomized trial with long-term outcomes is needed to definitively compare the effectiveness of these 2 revascularization strategies. (Hybrid Revascularization Observational Study; NCT01121263)
Source: Journal of the American College of Cardiology - July 21, 2016 Category: Cardiology Source Type: research

Comparative Effectiveness of Coronary Artery Bypass Grafting (CABG) Surgery and Percutaneous Coronary Intervention (PCI) in Elderly Patients with Diabetes.
CONCLUSIONS: CABG appears to be the preferred revascularization strategy for elderly patients with diabetes and coronary heart disease. However, this result should be interpreted considering study limitations, for example, several patient clinical variables and physician-related factors which may affect procedure outcomes are not available in the data. Clinical decisions should be individualized considering all patient and physician-related factors. PMID: 27479778 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - August 3, 2016 Category: Research Tags: Curr Med Res Opin Source Type: research

Estimating the economic burden of cardiovascular events in patients receiving lipid-modifying therapy in the UK
Conclusions Revascularisation and myocardial infarction were associated with the highest incremental costs following a CV event. On the basis of real-world data, the economic burden of CV events in the UK is substantial, particularly among those with greater comorbidity burden.
Source: BMJ Open - August 4, 2016 Category: Journals (General) Authors: Danese, M. D., Gleeson, M., Kutikova, L., Griffiths, R. I., Azough, A., Khunti, K., Seshasai, S. R. K., Ray, K. K. Tags: Open access, Cardiovascular medicine, Health economics, Health services research Source Type: research

Does Renin ‐Angiotensin System Blockade Protect Lupus Nephritis Patients From Atherosclerotic Cardiovascular Events? A Case–Control Study
ConclusionOur data do not support the hypothesis that ACE inhibitors/ARBs may be protective against atherosclerotic CVEs in LN patients.
Source: Arthritis Care and Research - August 18, 2016 Category: Rheumatology Authors: Konstantinos Tselios, Dafna D. Gladman, Jiandong Su, Murray B. Urowitz Tags: Original Article Source Type: research

Comparison between off- and on-pump coronary artery bypass grafting: long-term results of a real-world registry ADULT CARDIAC
CONCLUSIONS In patients undergoing elective isolated CABG, on-pump strategy conferred a long-term survival advantage compared with off-pump strategy, particularly for patients with more extensive coronary disease. No benefits were found in terms of reduction of postoperative morbidity with the off-pump strategy. On-pump surgery should be the preferred revascularization technique, and off-pump surgery reserved for patients for whom the perioperative risk of cardiopulmonary bypass is greater than the risk of a less complete coronary revascularization.
Source: European Journal of Cardio-Thoracic Surgery - August 30, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Nicolini, F., Fortuna, D., Contini, G. A., Pacini, D., Gabbieri, D., Zussa, C., De Palma, R., Vezzani, A., Gherli, T., on behalf of the RERIC (Registro dell'Emilia Romagna degli Interventi Cardiochirurgici) Investigators Tags: Molecular biology ADULT CARDIAC Source Type: research

Fast-track cardiac care for adult cardiac surgical patients.
CONCLUSIONS: Low-dose opioid-based general anaesthesia and time-directed extubation protocols for fast-track interventions have risks of mortality and major postoperative complications similar to those of conventional (not fast-track) care, and therefore appear to be safe for use in patients considered to be at low to moderate risk. These fast-track interventions reduced time to extubation and shortened length of stay in the intensive care unit but did not reduce length of stay in the hospital. PMID: 27616189 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - September 11, 2016 Category: Journals (General) Authors: Wong WT, Lai VK, Chee YE, Lee A Tags: Cochrane Database Syst Rev Source Type: research

Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial
Publication date: Available online 31 October 2016 Source:The Lancet Author(s): Timo Mäkikallio, Niels R Holm, Mitchell Lindsay, Mark S Spence, Andrejs Erglis, Ian B A Menown, Thor Trovik, Markku Eskola, Hannu Romppanen, Thomas Kellerth, Jan Ravkilde, Lisette O Jensen, Gintaras Kalinauskas, Rikard B A Linder, Markku Pentikainen, Anders Hervold, Adrian Banning, Azfar Zaman, Jamen Cotton, Erlend Eriksen, Sulev Margus, Henrik T Sørensen, Per H Nielsen, Matti Niemelä, Kari Kervinen, Jens F Lassen, Michael Maeng, Keith Oldroyd, Geoff Berg, Simon J Walsh, Colm G Hanratty, Indulis Kumsars, Peteris Stradins, Terje K Steigen, O...
Source: The Lancet - October 31, 2016 Category: Journals (General) Source Type: research

Comparative efficacy of coronary artery bypass surgery vs. percutaneous coronary intervention in patients with diabetes and multivessel coronary artery disease with or without chronic kidney disease
Conclusions Compared to PCI, the effects of CABG on long-term risks for MACCE observed in the FREEDOM trial are preserved among patients with mild to moderate CKD.
Source: European Heart Journal - December 29, 2016 Category: Cardiology Authors: Baber, U., Farkouh, M. E., Arbel, Y., Muntner, P., Dangas, G., Mack, M. J., Hamza, T. H., Mehran, R., Fuster, V. Tags: Clinical trial update Source Type: research