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Specialty: Rheumatology

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Total 576 results found since Jan 2013.

Stroke in systemic lupus erythematosus: epidemiology, mechanism, and long-term outcome.
CONCLUSIONS: The prevalence of stroke in this cohort was 3.1%. Ischemic strokes had a bimodal presentation, occurring either early after SLE diagnosis or after a several-year delay. Half of the hemorrhagic strokes occurred >10 years after the diagnosis of SLE. Clinical outcome was usually good with a relatively low recurrence rate. PMID: 32151182 [PubMed - as supplied by publisher]
Source: Lupus - March 8, 2020 Category: Rheumatology Authors: Guraieb-Chahín P, Cantú-Brito C, Soto-Mota A, Guerrero-Torres L, Flores-Silva F, Chiquete E, Fragoso-Loyo H, González-Duarte A, Valdés-Ferrer SI Tags: Lupus Source Type: research

Occurrence and relative risk of stroke in incident and prevalent contemporary rheumatoid arthritis
Conclusion The magnitude of stroke risk is lower than for ischaemic heart disease in RA, and the evolvement of this risk from RA diagnosis may be slower. This suggests different driving forces behind these two RA co-morbidities and has implications for the clinical follow-up of patients with RA.
Source: Annals of the Rheumatic Diseases - February 25, 2013 Category: Rheumatology Authors: Holmqvist, M., Gransmark, E., Mantel, A., Alfredsson, L., Jacobsson, L. T. H., Wallberg-Jonsson, S., Askling, J. Tags: Immunology (including allergy), Connective tissue disease, Degenerative joint disease, Musculoskeletal syndromes, Rheumatoid arthritis Clinical and epidemiological research Source Type: research

Factors relating to impaired stroke volume during the 6-minute walk test in patients with systemic sclerosis.
CONCLUSIONS: Impaired stroke volume in patients with systemic sclerosis was observed at rest and during exercise, and the factors relating to the cardiac response seemed to be pulmonary function and the extent of pulmonary hypertension. PMID: 27463117 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - July 28, 2016 Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

Transient ischemic attack and stroke in systemic lupus erythematosus.
Abstract Ischemic stroke is increased in systemic lupus erythematosus (SLE) patients. The differential diagnosis of stroke in SLE is complex. Transient ischemic attack and ischemic stroke share pathophysiologic mechanisms, but prognosis may vary depending on severity and cause, and definitions are dependent on the timing and extent of the diagnostic evaluation. In SLE patients with a history of transient ischemic attacks, stroke occurred in 57%. Cerebrovascular events account for 20% to 30% of deaths in patients with SLE. In SLE, both disease-specific and traditional stroke risk factors are important. PMID: 2...
Source: Lupus - October 11, 2013 Category: Rheumatology Authors: Timlin H, Petri M Tags: Lupus Source Type: research

Risk of myocardial infarction and ischaemic stroke in adults with polymyositis and dermatomyositis: a general population-based study
Conclusion. Our study demonstrates that PM and DM are both associated with an increased risk of MI but not ischaemic stroke. Our findings support increased vigilance in cardiovascular prevention, surveillance and risk modification in adults with PM and DM.
Source: Rheumatology - February 8, 2016 Category: Rheumatology Authors: Rai, S. K., Choi, H. K., Sayre, E. C., Avina-Zubieta, J. A. Tags: Myositis and Muscle Disease CLINICAL SCIENCE Source Type: research

Risk of Myocardial Infarction and Stroke in Patients with Granulomatosis with Polyangiitis: A Population‐Based Study
Conclusion: GPA patients have a significantly increased risk of MI, with a non‐statistically significant trend towards increased risk of ischemic stroke. Monitoring for this complication and vigilance in modifying risk factors is particularly warranted in this patient population, especially early after diagnosis. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - May 22, 2016 Category: Rheumatology Authors: J. Antonio Aviña‐Zubieta, Alice Mai, Neda Amiri, Natasha Dehghan, Ju Ann Tan, Eric C. Sayre, Hyon K. Choi Tags: Full Length Source Type: research

Risk of Myocardial Infarction and Stroke in Patients With Granulomatosis With Polyangiitis (Wegener's): A Population ‐Based Study
ConclusionPatients with GPA have a significantly increased risk of MI and a non–statistically significant trend toward an increased risk of ischemic stroke. Monitoring for this complication and vigilance in modifying risk factors are particularly warranted in this patient population, especially early after the diagnosis of GPA.
Source: Arthritis and Rheumatism - September 28, 2016 Category: Rheumatology Authors: J. Antonio Avi ña‐Zubieta, Alice Mai, Neda Amiri, Natasha Dehghan, Ju Ann Tan, Eric C. Sayre, Hyon K. Choi Tags: Full Length Source Type: research

Risk of Myocardial Infarction and Stroke in Newly Diagnosed Systemic Lupus Erythematosus: A General Population ‐Based Study
Conclusion: Patients with SLE have an increased risk of cardiovascular events, particularly during the first year after diagnosis. Increased vigilance in monitoring for these potentially fatal outcomes and their modifiable risk factors is recommended in this patient population. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - January 26, 2017 Category: Rheumatology Authors: J. Antonio Avi ña‐Zubieta, Fergus To, Kateryna Vostretsova, Mary De Vera, Eric C. Sayre, John M. Esdaile Tags: Original Article Source Type: research

Exploring metabolic and inflammatory abnormalities in rheumatoid arthritis patients developing stroke disease: a case-control study using electronic medical record data in northern China
ConclusionsA close monitoring is required for RA patients with dyslipidemia and elevated inflammatory markers, and the primary stroke preventive strategies should be directed against these risk factors.
Source: Clinical Rheumatology - February 7, 2019 Category: Rheumatology Source Type: research

Acute stroke in familial Mediterranean fever: An analysis of 23 new cases and systematic review of the literature
DiscussionThe acute stroke phenotype in FMF cases is herein described for the first time. Several clinicoradiological features such as thrombotic lacunar infarcts located in the central mesencephalon seem so typical that we recommend searching for FMF mutations in geographic regions where FMF is common.
Source: International Journal of Rheumatic Diseases - February 7, 2023 Category: Rheumatology Authors: Mehmet Akif Topcuoglu, Cansu Ayvacioglu ‐Cagan, Ethem Murat Arsava, Pınar Acar‐Ozen, Umut Kalyoncu, Rahsan Gocmen, Tayfun Hilmi Akbaba, Banu Balcı‐Peynircioğlu, Meryem Aslı Tuncer Tags: ORIGINAL ARTICLE Source Type: research

High risk of pulmonary embolism and deep venous thrombosis but not of stroke in granulomatosis with polyangiitis (Wegener’s)
Conclusion: The present study confirms that GPA patients have a markedly increased risk of venous thromboembolism. We did not observe an increased risk of stroke in our cohort. Thus, our observations demonstrate a differential impact of GPA and/or its treatment on the risk of various vascular events. © 2014 American College of Rheumatology.
Source: Arthritis Care and Research - July 29, 2014 Category: Rheumatology Authors: Mikkel Faurschou, Niels Obel, Bo Baslund Tags: Original Article Source Type: research

Methotrexate might reduce ischemic stroke in patients with rheumatoid arthritis: a population ‐based retrospective cohort study
ConclusionsAt a dosage of > 0.5 defined daily dose, short‐term methotrexate might decrease ischemic stroke risk in RA patients, while hydroxychloroquine and sulfasalazine were neutral.
Source: APLAR Journal of Rheumatology - January 1, 2018 Category: Rheumatology Authors: Hong ‐Wei Tam, Chyong‐Mei Chen, Pui‐Ying Leong, Chao‐Hsi Chen, Yuan‐Chao Li, Yu‐Hsun Wang, Li‐Chi Lin, Jeng‐Yuan Chiou, James Cheng‐Chung Wei Tags: Original Article Source Type: research

Genetic Variants of the NLRP3 Inflammasome Are Associated with Stroke in Patients with Rheumatoid Arthritis.
CONCLUSION: Genetic variants of the NLRP3 inflammasome influence the risk of stroke/TIA, but not of MI/angina pectoris in Swedish patients with established RA. PMID: 26178285 [PubMed - as supplied by publisher]
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Kastbom A, Ärlestig L, Rantapää-Dahlqvist S Tags: J Rheumatol Source Type: research

Trends in Hospitalizations Due to Acute Coronary Syndromes and Stroke in Patients with Systemic Lupus Erythematosus, 1996 To 2012
Conclusion: Increased awareness of the burden of CVD in patients with SLE has not yet translated into decreases in hospitalizations for acute myocardial infarction or stroke. This may be due to barriers in implementation of CVD risk factor modification, or SLE‐specific risks that have not yet been identified or effectively targeted. This article is protected by copyright. All rights reserved.
Source: Arthritis and Rheumatism - June 5, 2016 Category: Rheumatology Authors: Maria G. Tektonidou, Zhong Wang, Michael M. Ward Tags: Brief Report Source Type: research