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Condition: Reflex Sympathetic Dystrophy

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Total 1447 results found since Jan 2013.

Anodal tDCS of contralesional hemisphere modulates ipsilateral control of spinal motor networks targeting the paretic arm post-stroke
CONCLUSIONS: Stimulation of the undamaged cortex in stroke participants induces modulation of ipsilateral motor networks controlling the hemiparetic side.SIGNIFICANCE: Rehabilitation could leverage stimulation of the undamaged hemisphere to enhance motor recovery post stroke.PMID:35131634 | DOI:10.1016/j.clinph.2021.12.016
Source: Clinical Neurophysiology - February 8, 2022 Category: Neurology Authors: Wanalee Klomjai Alain Giron Mohamed Mounir El Mendili Claire Aymard Pascale Pradat-Diehl Nicolas Roche Rose Katz El éonore Bayen Alexandra Lackmy-Vallee Source Type: research

Retinal microvascular abnormalities and risks of incident stroke and its subtypes: The Circulatory Risk in Communities Study
Conclusion: Retinal microvascular abnormalities were positively associated with the risk of incident stroke in the general Japanese population. Routine retinal photography could provide positive clinical insights into stroke risk stratification independent of blood pressure, antihypertensive medication use, and other risk factors.
Source: Journal of Hypertension - March 10, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Immediate and short-term effects of continuous theta burst transcranial magnetic stimulation over contralesional premotor area on post-stroke spasticity in patients with severe hemiplegia: Study protocol for a randomized controlled trial
This study aims to demonstrate the immediate and short-term efficacy of continuous theta-burst stimulation (cTBS) targeting cPMA on upper limb spasticity in severe subacute stroke patients.MethodsThis trial is a single-center, prospective, three-group randomized controlled trial. Forty-five eligible patients will be recruited and randomized into three groups: the sham-cTBS group (sham cTBS targeting contralesional PMA), the cTBS-cM1 group (cTBS targeting contralesional M1), and the cTBS-cPMA group (cTBS targeting contralesional PMA). All subjects will undergo comprehensive rehabilitation and the corresponding cTBS interven...
Source: Frontiers in Neurology - August 23, 2022 Category: Neurology Source Type: research

Plastic changes in spinal synaptic transmission following botulinum toxin A in patients with post-stroke spasticity.
CONCLUSION: Botulinum toxin treatment induces synaptic plasticity at the Ia-motoneuron synapse in post-stroke paretic patients, which suggests that the effectiveness of botulinum toxin-type A in post-stroke rehabilitation might be partly due to its central effects. PMID: 26424152 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - October 3, 2015 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Facial Colliculus and Opalski Stroke Syndromes Caused by Vertebral Artery Dissection. Case Report (P4.349)
Conclusion: Brainstem stroke syndromes are challenging to localize before brain imaging. In this case two embolic strokes happened. The first in the right facial colliculus causing the right 6th and 7th cranial nerves palsy. The second happened in the left lateral medulla extending below the pyramidal decussation causing a classical left lateral medullary syndrome with ipsilateral hemiparesis, which constitute a left Opalski stroke syndrome.Disclosure: Dr. Alghamdi has nothing to disclose. Dr. Ayoub has nothing to disclose. Dr. Alzahrani has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Alghamdi, S., Ayoub, O., Alzahrani, N. Tags: Cerebrovascular Case Reports Source Type: research

The Reciprocal Interaction of Sympathetic Nervous System and cAMP-PKA-NF-kB Pathway in Immune Suppression after Experimental Stroke
Conclusion On account of the SNS activation after stroke, epinephrine activates the expression of cAMP, which further increases the level of PKA. Therefore, the level of nuclear factor NF-kB is down-regulated. Since the pro-inflammatory effect of NF-kB slacked, the immune system may be inhibited after stroke.
Source: Neuroscience Letters - May 28, 2016 Category: Neuroscience Source Type: research

Reflex-mediated dynamic neuromuscular stabilization in stroke patients: EMG processing and ultrasound imaging.
CONCLUSIONS: Our novel results provide the first clinical evidence that DNS is more effective than NDT in both healthy and hemiparetic stroke subjects to provide superior deep core muscle activation, core stabilization, and muscle thickness. Moreover, such advantageous therapeutic benefits of the DNS core stabilization exercise over the NDT exercise were more apparent in the hemiparetis stroke patients than normal controls. PMID: 28582897 [PubMed - as supplied by publisher]
Source: Technology and Health Care - May 19, 2017 Category: Medical Devices Authors: Yoon HS, You JSH Tags: Technol Health Care Source Type: research

Relationship between spasticity and spinal neural circuits in patients with chronic hemiparetic stroke.
Abstract Spasticity is a common problem in patients with stroke that contributes to motor dysfunction. However, the pathophysiological mechanisms underlying spasticity are not fully understood. The purpose of the present study was to explain the relationship between features of spinal neural circuits assessed using electrophysiological techniques and the clinical manifestations of stroke. The participants were 71 patients with chronic hemiparetic stroke. To assess spinal neural circuits, Hmax/Mmax of the forearm flexor muscles and reciprocal inhibition (RI) between forearm extensor and flexor muscles with the H re...
Source: Experimental Brain Research - November 8, 2017 Category: Neuroscience Authors: Okuyama K, Kawakami M, Hiramoto M, Muraoka K, Fujiwara T, Liu M Tags: Exp Brain Res Source Type: research

Comprehensive non-invasive cardiac and autonomic assessment in acute ischaemic stroke patients: pilot study.
CONCLUSIONS: Patients with acute ischemic stroke after a recovery period presented autonomic imbalance and impaired cardiac sympathetic modulation at rest and in response to orthostatic challenge compared to a control group. Furthermore, there was a statistically significant decrease in baroreflex sensitivity, suggesting parasympathetic deficiency. PMID: 29393601 [PubMed - as supplied by publisher]
Source: Minerva Cardioangiologica - February 3, 2018 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

The cardiac autonomic nervous system response to different daily demands among patients at the sub-acute phase post ischemic stroke and healthy controls.
CONCLUSION: Patients post-stroke experience hyper sympathetic function at rest and less adaptive cardiac autonomic control during different activities, which all may have an impact on rehabilitation outcomes. PMID: 29660948 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - April 19, 2018 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Activation of elbow extensors during passive stretch of flexors in patients with post-stroke spasticity.
CONCLUSIONS: Stroke may result in both limitations in reciprocal inhibition and excessive agonist-antagonist co-activation, likely from deficits in TSRT modulation in both muscle groups. SIGNIFICANCE: Since both reciprocal inhibition and co-activation are fundamental to normal motor control, their cooperative action should be considered in designing interventions to increase the ranges of regulation of TSRTs in flexors and extensors to enhance upper limb functional recovery. PMID: 30077867 [PubMed - as supplied by publisher]
Source: Clinical Neurophysiology - July 24, 2018 Category: Neurology Authors: Levin MF, Solomon JM, Shah A, Blanchette AK, Feldman AG Tags: Clin Neurophysiol Source Type: research

Quantifying Altered Neural Connectivity of the Stretch Reflex in Chronic Hemiparetic Stroke
This study provides new evidence of changes in neural connectivity and long-latency time lag in the stretch reflex response post-stroke. The results suggest the contribution of indirect motor pathways to synergy-related spasticity.
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - May 31, 2020 Category: Neuroscience Source Type: research

Early rehabilitation after stroke: relationship between the heart rate variability and functional outcome
ConclusionsThe presence of autonomic cardiovascular dysregulation in patients with subacute stroke was associated with adverse functional outcome after the early post ‐stroke rehabilitation.
Source: ESC Heart Failure - July 29, 2020 Category: Cardiology Authors: Nadja Scherbakov, Anush Barkhudaryan, Nicole Ebner, Stephan Haehling, Stefan D. Anker, Michael Joebges, Wolfram Doehner Tags: Original Research Article Source Type: research

Delayed retinal vein recovery responses indicate both non-adaptation to stress as well as increased risk for stroke: the SABPA study.
CONCLUSIONS: In response to low norepinephrine, a reflex increase in SAM activity occurred, enhancing arterial vasoconstriction and hypo-perfusion. Concomitant HPA dysregulation attenuated retinal vein vasoactivity and tone, reflecting delayed vein recovery responses and non-adaptation to stress. These constrained vein recovery responses are indicative of increased chronic stress and stroke risk. PMID: 33104153 [PubMed - as supplied by publisher]
Source: Cardiovascular Journal of Africa - October 26, 2020 Category: Cardiology Authors: Malan L, Hamer M, von Känel R, Kotliar K, van Wyk RD, Lambert GW, Vilser W, Ziemssen T, Schlaich MP, Smith W, Magnusson M, Wentzel A, Myburgh CE, Steyn HS, Malan NT Tags: Cardiovasc J Afr Source Type: research

Liver vitronectin release into the bloodstream increases due to reduced vagal muscarinic signaling after cerebral stroke in female mice
Keasey et al., show that an increase in plasma vitronectin after ischemic stroke in female mice is produced by release from the liver. They show that vitronectin production is inhibited by the vagus nerve through muscarinic M1/3 receptors and can be blocked by systemic treatment with bethanechol. These findings are relevant to diseases characterized by detrimental vitronectin levels. AbstractVitronectin (VTN) is a glycoprotein enriched in the blood and activates integrin receptors. VTN blood levels increase only in female mice 24  h after an ischemic stroke and exacerbate brain injury through IL-6-driven inflammation, but...
Source: Physiological Reports - May 9, 2022 Category: Physiology Authors: Matthew P. Keasey, Chiharu Lovins, Cuihong Jia, Theo Hagg Tags: ORIGINAL ARTICLE Source Type: research