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Condition: Reflex Sympathetic Dystrophy

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Total 1447 results found since Jan 2013.

Upregulation of muscle sympathetic nerve activity in acute ischemic middle cerebral artery infarction is a risk factor for bacterial infection after stroke.
Acute ischemic stroke induces systemic complications via activation of sympathetic autonomic nervous system. While cardiovascular complications3 are well known, CNS injury-induced immunodepression2,3,4 has recently moved into scientific focus. To date, no direct evidence of increased muscle sympathetic nerve activity (MSNA) has been shown in acute cerebral ischemia. In this pilot study, we sought to determine whether MSNA recording is feasible within emergency setting of acute stroke care. We measured MSNA in seven patients (m:f 5:2; age range 47–74 yrs.) within 48 hr of onset of acute ischemic stroke and following a reh...
Source: Autonomic Neuroscience: Basic and Clinical - August 26, 2015 Category: Neuroscience Authors: C Noack, K. Heußer, J. Tank, K. Weißenborn, C. Meisel, A. Meisel, A. Lipp Tags: 21.5 Source Type: research

Is the Frequency in Somatosensory Electrical Stimulation the Key Parameter in Modulating the Corticospinal Excitability of Healthy Volunteers and Stroke Patients with Spasticity?
Abstract Somatosensory electrical stimulation (SES) has been proposed as an approach to treat patients with sensory-motor impairment such as spasticity. However, there is still no consensus regarding which would be the adequate SES parameters to treat those deficits. Therefore, the aim of this study was to evaluate the effects of applying SES over the forearm muscles at four different frequencies of stimulation (3, 30, 150, and 300 Hz) and in two intervals of time (5' and 30') by means of transcranial magnetic stimulation and Hoffmann's reflex (H-reflex) in healthy volunteers (Experiments  I and II). A group...
Source: Neural Plasticity - February 18, 2016 Category: Neurology Authors: Garcia MA, Catunda JM, de Souza MN, Fontana AP, Sperandei S, Vargas CD Tags: Neural Plast Source Type: research

Improved cardiac filling facilitates the postprandial elevation of stroke volume in Python regius RESEARCH ARTICLE
Sanne Enok, Gabriella Leite, Cleo Leite, Hans Gesser, Michael S. Hedrick, and Tobias WangTo accommodate the pronounced metabolic response to digestion, pythons increase both heart rate and elevate stroke volume, where the latter has been ascribed to a massive and fast cardiac hypertrophy. However, numerous recent studies show that heart mass rarely increases even upon ingestion of large meals, and we therefore explored the possibility that a rise in mean circulatory filling pressure (MCFP) serves to elevate venous pressure and cardiac filling during digestion. To this end, we measured blood flows and pressures in anaesthet...
Source: Journal of Experimental Biology - July 20, 2016 Category: Biology Authors: Enok, S., Leite, G., Leite, C., Gesser, H., Hedrick, M. S., Wang, T. Tags: RESEARCH ARTICLE Source Type: research

Body Schema Plasticity after Stroke: Subjective and Neurophysiological Correlates of the Rubber Hand Illusion
Publication date: Available online 8 January 2017 Source:Neuropsychologia Author(s): Roberto Llorens, Adrián Borrego, Priscila Palomo, Ausiàs Cebolla, Enrique Noé, Sergi Bermúdez i Badia, Rosa Baños Stroke can lead to motor impairments that can affect the body structure and restraint mobility. We hypothesize that brain lesions and their motor sequelae can distort the body schema, a sensorimotor map of body parts and elements in the peripersonal space through which human beings embody the reachable space and ready the body for forthcoming movements. Two main constructs have been identified in the embodiment mechanism:...
Source: Neuropsychologia - January 7, 2017 Category: Neurology Source Type: research

Stroke in right dorsal anterior insular cortex is related to myocardial injury
This article is protected by copyright. All rights reserved.
Source: Annals of Neurology - March 1, 2017 Category: Neurology Authors: Thomas Krause, Kathrin Werner, Jochen B. Fiebach, Kersten Villringer, Sophie K. Piper, Karl Georg Haeusler, Matthias Endres, Jan F. Scheitz, Christian H. Nolte Tags: Research Article Source Type: research

Increased infections with β-blocker use in ischemic stroke, a β 2 -receptor mediated process?
This study adds to this literature using propensity score matching to limit confounding and by examining the effects of selective and non-selective β-blockers. Prospective data from acute ischemic stroke admissions at a single center f rom July 2010–June 2015 were analyzed. Outcomes included infection (urinary tract infection [UTI], pneumonia, or bacteremia), discharge modified Rankin Score (mRS), and in-hospital death. Any selective and non-selective β-blocker use during the first 3 days of admission were investigated with pr opensity score matching. A sensitivity analysis was also performed. This study included 1431...
Source: Neurological Sciences - March 2, 2017 Category: Neurology Source Type: research

The impact of lesion location on dysphagia incidence, pattern and complications in acute stroke. Part 2: Oropharyngeal residue, swallow and cough response, and pneumonia
ConclusionsThis study gives new insights on the cortical representation of single components of swallowing and airway protection behaviours. The lesion model may help to risk‐stratify patients for dysphagia and pneumonia based on their brain scan.
Source: European Journal of Neurology - April 28, 2017 Category: Neurology Authors: S. Suntrup ‐Krueger, A. Kemmling, T. Warnecke, C. Hamacher, S. Oelenberg, T. Niederstadt, W. Heindel, H. Wiendl, R. Dziewas Tags: Original Article Source Type: research

Measurement of post-stroke spasticity based on tonic stretch reflex threshold: implications of stretch velocity for clinical practice.
CONCLUSIONS: The results showed that the stretch protocols were not all the same and that the method of increasing was most suitable for performing manual passive stretches to evaluate TSRT in these patients. Another analysis was the correlation between MAS and tonic stretch reflex threshold; a weak correlation was observed between the increasing and decreasing methods, and moderate correlation was observed between the random methods. Implications for Rehabilitation We demonstrated that the protocol of execution of passive stretches influences in the measurement of the tonic stretch reflex threshold (TSRT). We recommend th...
Source: Disability and Rehabilitation - October 2, 2017 Category: Rehabilitation Authors: Marques IA, Silva MB, Silva AN, Luiz LMD, Soares AB, Naves ELM Tags: Disabil Rehabil Source Type: research

Increase of Substance P Concentration in Saliva after Pharyngeal Electrical Stimulation in Severely Dysphagic Stroke Patients – an Indicator of Decannulation Success?
Conclusions: The physiological mechanism of PES may consist in restoration of sensory feedback, which is known to be crucial for the execution of a safe swallow. SP possibly acts as a biomarker for indicating response to PES.Neurosignals 2017;25:74 –87
Source: Neurosignals - October 17, 2017 Category: Neurology Source Type: research

Beat-to-beat blood pressure variability and heart rate variability in relation to autonomic dysregulation in patients with acute mild-moderate ischemic stroke
Publication date: Available online 12 March 2019Source: Journal of Clinical NeuroscienceAuthor(s): Ge Tian, Li Xiong, Howan Leung, Yannie Soo, Thomas Leung, Lawrence Ka-sing WongAbstractAutonomic dysregulation is common in post-stroke patients. We aimed to correlate beat-to-beat blood pressure variability (BPV) and heart rate variability (HRV) with Ewing’s test classification. We enrolled patients with acute ischemic stroke. Autonomic function was assessed by Ewing battery and dichotomized into minor or significant group. Beat-to-beat blood pressure and heart rate were monitored for calculating the frequency components o...
Source: Journal of Clinical Neuroscience - March 13, 2019 Category: Neuroscience Source Type: research

Transplantation of neural progenitor cells generated from human urine epithelial cell-derived induced pluripotent stem cells improves neurological functions in rats with stroke.
In this study, we differentiated NPCs from a urine-derived iPSC line (UC-05) which was generated with optimized episomal vectors in a feeder-free culture system. UC-05 can be induced into NPCs efficiently in monolayer cultures using dual SMAD inhibitions, and have the ability to differentiate further into astrocytes and functional neurons in vitro. We then characterized UC-05-derived NPCs upon transplantation into the striatum of adult male rats subjected to transient middle cerebral artery occlusion (tMCAO) reperfusion. While NPCs were grafted into rats 7 days before the MCAO surgery, cells were found to migrate from the ...
Source: Discovery Medicine - July 1, 2020 Category: Research Tags: Discov Med Source Type: research

Asymmetry of Reflex Thresholds Between Contralateral Limbs in Hemispheric Stroke Survivors and Dominant Limbs in Neurologically Intact Individuals
To investigate the difference in stretch reflex thresholds between the contralateral limb in hemispheric stroke survivors and the dominant limb of neurologically intact individuals. We hypothesize that after hemispheric stroke, alterations in the excitability of the reticulospinal tract affects neurons on both sides of the spinal cord, and thereby contributes to hyperexcitability of reflex pathways on both sides of stroke survivors (as compared to neurologically intact subjects).
Source: Archives of Physical Medicine and Rehabilitation - October 24, 2020 Category: Rehabilitation Authors: Taimoor Afzal, Matthieu Chardon, William Rymer, Nina Suresh Tags: Oral Research Presentation Source Type: research

In vivo multimodal imaging of adenosine A1 receptors in neuroinflammation after experimental stroke
Conclusion: Notably, these data provide evidence for A1ARs playing a key role in the control of both the activation of resident glia and the de novo proliferation of microglia and macrophages after experimental stroke in rats.
Source: Theranostics - January 15, 2021 Category: Molecular Biology Authors: Ana Joya, Mar í a Ardaya, Alejandro Montilla, Maider Garbizu, Sandra Plaza-Garc í a, Vanessa G ó mez-Vallejo, Daniel Padro, Juan Jos é Guti é rrez, Xabier Rios, Pedro Ramos-Cabrer, Unai Coss í o, Krishna R Pulagam, Makoto Higuchi, Mar í a Domercq, Tags: Research Paper Source Type: research