Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized Controlled Study
Neural Plast. 2022 Jan 5;2022:3815357. doi: 10.1155/2022/3815357. eCollection 2022.ABSTRACTOBJECTIVE: To determine the long-term effects of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) over the contralesional M1 preceding motor task practice on the interhemispheric asymmetry of the cortical excitability and the functional recovery in subacute stroke patients with mild to moderate arm paresis.METHODS: Twenty-four subacute stroke patients were randomly allocated to either the experimental or control group. The experimental group underwent rTMS over the contralesional M1 (1 Hz), immediately followed by...
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Ka Yan Luk Hui Xi Ouyang Marco Yiu Chung Pang Source Type: research

Disrupted Dynamic Functional Connectivity of the Visual Network in Episodic Patients with Migraine without Aura
CONCLUSIONS: The dFC abnormalities of the visual cortex may be involved in pain integration with multinetworks and associated with anxiety disorder in episodic MwoA patients.PMID:35035474 | PMC:PMC8754605 | DOI:10.1155/2022/9941832 (Source: Neural Plasticity)
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Heng-Le Wei Tian Tian Gang-Ping Zhou Jin-Jin Wang Xi Guo Yu-Chen Chen Yu-Sheng Yu Xindao Yin Junrong Li Hong Zhang Source Type: research

Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized Controlled Study
Neural Plast. 2022 Jan 5;2022:3815357. doi: 10.1155/2022/3815357. eCollection 2022.ABSTRACTOBJECTIVE: To determine the long-term effects of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) over the contralesional M1 preceding motor task practice on the interhemispheric asymmetry of the cortical excitability and the functional recovery in subacute stroke patients with mild to moderate arm paresis.METHODS: Twenty-four subacute stroke patients were randomly allocated to either the experimental or control group. The experimental group underwent rTMS over the contralesional M1 (1 Hz), immediately followed by...
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Ka Yan Luk Hui Xi Ouyang Marco Yiu Chung Pang Source Type: research

Disrupted Dynamic Functional Connectivity of the Visual Network in Episodic Patients with Migraine without Aura
CONCLUSIONS: The dFC abnormalities of the visual cortex may be involved in pain integration with multinetworks and associated with anxiety disorder in episodic MwoA patients.PMID:35035474 | PMC:PMC8754605 | DOI:10.1155/2022/9941832 (Source: Neural Plasticity)
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Heng-Le Wei Tian Tian Gang-Ping Zhou Jin-Jin Wang Xi Guo Yu-Chen Chen Yu-Sheng Yu Xindao Yin Junrong Li Hong Zhang Source Type: research

Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized Controlled Study
Neural Plast. 2022 Jan 5;2022:3815357. doi: 10.1155/2022/3815357. eCollection 2022.ABSTRACTOBJECTIVE: To determine the long-term effects of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) over the contralesional M1 preceding motor task practice on the interhemispheric asymmetry of the cortical excitability and the functional recovery in subacute stroke patients with mild to moderate arm paresis.METHODS: Twenty-four subacute stroke patients were randomly allocated to either the experimental or control group. The experimental group underwent rTMS over the contralesional M1 (1 Hz), immediately followed by...
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Ka Yan Luk Hui Xi Ouyang Marco Yiu Chung Pang Source Type: research

Disrupted Dynamic Functional Connectivity of the Visual Network in Episodic Patients with Migraine without Aura
CONCLUSIONS: The dFC abnormalities of the visual cortex may be involved in pain integration with multinetworks and associated with anxiety disorder in episodic MwoA patients.PMID:35035474 | PMC:PMC8754605 | DOI:10.1155/2022/9941832 (Source: Neural Plasticity)
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Heng-Le Wei Tian Tian Gang-Ping Zhou Jin-Jin Wang Xi Guo Yu-Chen Chen Yu-Sheng Yu Xindao Yin Junrong Li Hong Zhang Source Type: research

Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized Controlled Study
Neural Plast. 2022 Jan 5;2022:3815357. doi: 10.1155/2022/3815357. eCollection 2022.ABSTRACTOBJECTIVE: To determine the long-term effects of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) over the contralesional M1 preceding motor task practice on the interhemispheric asymmetry of the cortical excitability and the functional recovery in subacute stroke patients with mild to moderate arm paresis.METHODS: Twenty-four subacute stroke patients were randomly allocated to either the experimental or control group. The experimental group underwent rTMS over the contralesional M1 (1 Hz), immediately followed by...
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Ka Yan Luk Hui Xi Ouyang Marco Yiu Chung Pang Source Type: research

Disrupted Dynamic Functional Connectivity of the Visual Network in Episodic Patients with Migraine without Aura
CONCLUSIONS: The dFC abnormalities of the visual cortex may be involved in pain integration with multinetworks and associated with anxiety disorder in episodic MwoA patients.PMID:35035474 | PMC:PMC8754605 | DOI:10.1155/2022/9941832 (Source: Neural Plasticity)
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Heng-Le Wei Tian Tian Gang-Ping Zhou Jin-Jin Wang Xi Guo Yu-Chen Chen Yu-Sheng Yu Xindao Yin Junrong Li Hong Zhang Source Type: research

Low-Frequency rTMS over Contralesional M1 Increases Ipsilesional Cortical Excitability and Motor Function with Decreased Interhemispheric Asymmetry in Subacute Stroke: A Randomized Controlled Study
Neural Plast. 2022 Jan 5;2022:3815357. doi: 10.1155/2022/3815357. eCollection 2022.ABSTRACTOBJECTIVE: To determine the long-term effects of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) over the contralesional M1 preceding motor task practice on the interhemispheric asymmetry of the cortical excitability and the functional recovery in subacute stroke patients with mild to moderate arm paresis.METHODS: Twenty-four subacute stroke patients were randomly allocated to either the experimental or control group. The experimental group underwent rTMS over the contralesional M1 (1 Hz), immediately followed by...
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Ka Yan Luk Hui Xi Ouyang Marco Yiu Chung Pang Source Type: research

Disrupted Dynamic Functional Connectivity of the Visual Network in Episodic Patients with Migraine without Aura
CONCLUSIONS: The dFC abnormalities of the visual cortex may be involved in pain integration with multinetworks and associated with anxiety disorder in episodic MwoA patients.PMID:35035474 | PMC:PMC8754605 | DOI:10.1155/2022/9941832 (Source: Neural Plasticity)
Source: Neural Plasticity - January 17, 2022 Category: Neurology Authors: Heng-Le Wei Tian Tian Gang-Ping Zhou Jin-Jin Wang Xi Guo Yu-Chen Chen Yu-Sheng Yu Xindao Yin Junrong Li Hong Zhang Source Type: research

Aberrant Resting-State Functional Connectivity of the Dorsal Attention Network in Tinnitus
Neural Plast. 2021 Dec 31;2021:2804533. doi: 10.1155/2021/2804533. eCollection 2021.ABSTRACTPrevious functional magnetic resonance imaging (fMRI) analyses have shown that the dorsal attention network (DAN) is involved in the pathophysiological changes of tinnitus, but few relevant studies have been conducted, and the conclusions to date are not uniform. The purpose of this research was to test whether there is a change in intrinsic functional connectivity (FC) patterns between the DAN and other brain regions in tinnitus patients. Thirty-one patients with persistent tinnitus and thirty-three healthy controls were enrolled i...
Source: Neural Plasticity - January 10, 2022 Category: Neurology Authors: Haimeng Hu Yining Lyu Shihong Li Zheng Yuan Chuntao Ye Zhao Han Guangwu Lin Source Type: research

Aberrant Resting-State Functional Connectivity of the Dorsal Attention Network in Tinnitus
Neural Plast. 2021 Dec 31;2021:2804533. doi: 10.1155/2021/2804533. eCollection 2021.ABSTRACTPrevious functional magnetic resonance imaging (fMRI) analyses have shown that the dorsal attention network (DAN) is involved in the pathophysiological changes of tinnitus, but few relevant studies have been conducted, and the conclusions to date are not uniform. The purpose of this research was to test whether there is a change in intrinsic functional connectivity (FC) patterns between the DAN and other brain regions in tinnitus patients. Thirty-one patients with persistent tinnitus and thirty-three healthy controls were enrolled i...
Source: Neural Plasticity - January 10, 2022 Category: Neurology Authors: Haimeng Hu Yining Lyu Shihong Li Zheng Yuan Chuntao Ye Zhao Han Guangwu Lin Source Type: research

Aberrant Resting-State Functional Connectivity of the Dorsal Attention Network in Tinnitus
Neural Plast. 2021 Dec 31;2021:2804533. doi: 10.1155/2021/2804533. eCollection 2021.ABSTRACTPrevious functional magnetic resonance imaging (fMRI) analyses have shown that the dorsal attention network (DAN) is involved in the pathophysiological changes of tinnitus, but few relevant studies have been conducted, and the conclusions to date are not uniform. The purpose of this research was to test whether there is a change in intrinsic functional connectivity (FC) patterns between the DAN and other brain regions in tinnitus patients. Thirty-one patients with persistent tinnitus and thirty-three healthy controls were enrolled i...
Source: Neural Plasticity - January 10, 2022 Category: Neurology Authors: Haimeng Hu Yining Lyu Shihong Li Zheng Yuan Chuntao Ye Zhao Han Guangwu Lin Source Type: research

Aberrant Resting-State Functional Connectivity of the Dorsal Attention Network in Tinnitus
Neural Plast. 2021 Dec 31;2021:2804533. doi: 10.1155/2021/2804533. eCollection 2021.ABSTRACTPrevious functional magnetic resonance imaging (fMRI) analyses have shown that the dorsal attention network (DAN) is involved in the pathophysiological changes of tinnitus, but few relevant studies have been conducted, and the conclusions to date are not uniform. The purpose of this research was to test whether there is a change in intrinsic functional connectivity (FC) patterns between the DAN and other brain regions in tinnitus patients. Thirty-one patients with persistent tinnitus and thirty-three healthy controls were enrolled i...
Source: Neural Plasticity - January 10, 2022 Category: Neurology Authors: Haimeng Hu Yining Lyu Shihong Li Zheng Yuan Chuntao Ye Zhao Han Guangwu Lin Source Type: research

Aberrant Resting-State Functional Connectivity of the Dorsal Attention Network in Tinnitus
Neural Plast. 2021 Dec 31;2021:2804533. doi: 10.1155/2021/2804533. eCollection 2021.ABSTRACTPrevious functional magnetic resonance imaging (fMRI) analyses have shown that the dorsal attention network (DAN) is involved in the pathophysiological changes of tinnitus, but few relevant studies have been conducted, and the conclusions to date are not uniform. The purpose of this research was to test whether there is a change in intrinsic functional connectivity (FC) patterns between the DAN and other brain regions in tinnitus patients. Thirty-one patients with persistent tinnitus and thirty-three healthy controls were enrolled i...
Source: Neural Plasticity - January 10, 2022 Category: Neurology Authors: Haimeng Hu Yining Lyu Shihong Li Zheng Yuan Chuntao Ye Zhao Han Guangwu Lin Source Type: research

Aberrant Resting-State Functional Connectivity of the Dorsal Attention Network in Tinnitus
Neural Plast. 2021 Dec 31;2021:2804533. doi: 10.1155/2021/2804533. eCollection 2021.ABSTRACTPrevious functional magnetic resonance imaging (fMRI) analyses have shown that the dorsal attention network (DAN) is involved in the pathophysiological changes of tinnitus, but few relevant studies have been conducted, and the conclusions to date are not uniform. The purpose of this research was to test whether there is a change in intrinsic functional connectivity (FC) patterns between the DAN and other brain regions in tinnitus patients. Thirty-one patients with persistent tinnitus and thirty-three healthy controls were enrolled i...
Source: Neural Plasticity - January 10, 2022 Category: Neurology Authors: Haimeng Hu Yining Lyu Shihong Li Zheng Yuan Chuntao Ye Zhao Han Guangwu Lin Source Type: research

Early Repetitive Transcranial Magnetic Stimulation Exerts Neuroprotective Effects and Improves Motor Functions in Hemiparkinsonian Rats
Neural Plast. 2021 Dec 27;2021:1763533. doi: 10.1155/2021/1763533. eCollection 2021.ABSTRACTRepetitive transcranial magnetic stimulation (rTMS) is a popular noninvasive technique for modulating motor cortical plasticity and has therapeutic potential for the treatment of Parkinson's disease (PD). However, the therapeutic benefits and related mechanisms of rTMS in PD are still uncertain. Accordingly, preclinical animal research is helpful for enabling translational research to explore an effective therapeutic strategy and for better understanding the underlying mechanisms. Therefore, the current study was designed to identif...
Source: Neural Plasticity - January 6, 2022 Category: Neurology Authors: Tsung-Hsun Hsieh Xiao-Kuo He Hui-Hua Liu Jia-Jin J Chen Chih-Wei Peng Hao-Li Liu Alexander Rotenberg Ko-Ting Chen Ming-Yuan Chang Yung-Hsiao Chiang Pi-Kai Chang Chi-Wei Kuo Source Type: research

Early Repetitive Transcranial Magnetic Stimulation Exerts Neuroprotective Effects and Improves Motor Functions in Hemiparkinsonian Rats
Neural Plast. 2021 Dec 27;2021:1763533. doi: 10.1155/2021/1763533. eCollection 2021.ABSTRACTRepetitive transcranial magnetic stimulation (rTMS) is a popular noninvasive technique for modulating motor cortical plasticity and has therapeutic potential for the treatment of Parkinson's disease (PD). However, the therapeutic benefits and related mechanisms of rTMS in PD are still uncertain. Accordingly, preclinical animal research is helpful for enabling translational research to explore an effective therapeutic strategy and for better understanding the underlying mechanisms. Therefore, the current study was designed to identif...
Source: Neural Plasticity - January 6, 2022 Category: Neurology Authors: Tsung-Hsun Hsieh Xiao-Kuo He Hui-Hua Liu Jia-Jin J Chen Chih-Wei Peng Hao-Li Liu Alexander Rotenberg Ko-Ting Chen Ming-Yuan Chang Yung-Hsiao Chiang Pi-Kai Chang Chi-Wei Kuo Source Type: research

Effectiveness of Contralaterally Controlled Functional Electrical Stimulation versus Neuromuscular Electrical Stimulation on Upper Limb Motor Functional Recovery in Subacute Stroke Patients: A Randomized Controlled Trial
Neural Plast. 2021 Dec 22;2021:1987662. doi: 10.1155/2021/1987662. eCollection 2021.ABSTRACTPURPOSE: To compare the effectiveness of contralaterally controlled functional electrical stimulation (CCFES) versus neuromuscular electrical stimulation (NMES) on motor recovery of the upper limb in subacute stroke patients.MATERIALS AND METHODS: Fifty patients within six months poststroke were randomly assigned to the CCFES group (n = 25) and the NMES group (n = 25). Both groups underwent routine rehabilitation plus 20-minute stimulation on wrist extensors per day, five days a week, for 3 weeks. Fugl-Meyer Assessment of upper extr...
Source: Neural Plasticity - January 3, 2022 Category: Neurology Authors: Songhua Huang Peile Liu Yinglun Chen Beiyao Gao Yingying Li Chan Chen Yulong Bai Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Investigation of Neuron Latency Modulated by Bilateral Inferior Collicular Interactions Using Whole-Cell Patch Clamp Recording in Brain Slices
In this study, we explored the synaptic mechanism of the effect of bilateral IC interactions on the latency of IC neurons. We used whole-cell patch clamp recordings to assess synaptic responses in isolated brain slices of Kunming mice. The results demonstrated that the excitation-inhibition projection was the main projection between the bilateral IC. Also, the bilateral IC interactions could change the reaction latency of most neurons to different degrees. The variation in latency was related to the type of synaptic input and the relative intensity of the excitation and inhibition. Furthermore, the latency variation also w...
Source: Neural Plasticity - December 20, 2021 Category: Neurology Authors: Jinzhe Ma Yangyang Han Yiting Yao Huimei Wang Mengxia Chen Ziying Fu Qicai Chen Jia Tang Source Type: research

Distinctive Gut Microbiota Alteration Is Associated with Poststroke Functional Recovery: Results from a Prospective Cohort Study
This study was designed to explore the poststroke alterations of gut microbiota and potential correlations between gut microbiota and global functions.METHODS: A total of thirty-eight patients with stroke and thirty-five healthy demographics-matched controls were recruited. Their fecal DNAs were extracted, and the V3-V4 regions of the conserved bacterial 16S RNA were amplified and sequenced on the Illumina MiSeq platform. Microbial composition, diversity indices, and species cooccurrence were compared between groups. Random forest and receiver operating characteristic analysis were used to identify potential diagnostic bio...
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Yini Dang Xintong Zhang Yu Zheng Binbin Yu Dijia Pan Xiaomin Jiang Chengjie Yan Qiuyu Yu Xiao Lu Source Type: research

Sports Augmented Cognitive Benefits: An fMRI Study of Executive Function with Go/NoGo Task
This study explores the effect of dynamic neural network processing with the classic Go/NoGo task with regular exercisers. We used functional magnetic resonance imaging to analyze the brain activation of areas involved in executive function, especially inhibitory control. Nineteen regular joggers and twenty-one subjects as a control group performed the task, and their brain imaging data were analyzed. The results showed that at the attentive visual period, the frontal and parietal areas, including the prefrontal cortex, putamen, thalamus, lingual, fusiform, and caudate, were significantly enhanced in positive activities th...
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Qingguo Ding Lina Huang Jie Chen Farzaneh Dehghani Juan Du Yingli Li Qin Li Hongqiang Zhang Zhen Qian Wenbin Shen Xiaowei Yin Pei Liang Source Type: research

Soleus H-Reflex Change in Poststroke Spasticity: Modulation due to Body Position
CONCLUSIONS: The motor neuron excitability of both sides was not suppressed but instead upregulated in the standing position in subjects with spasticity, which may suggest that there was abnormal regulation of the Ia pathway on both sides.PMID:34917144 | PMC:PMC8670919 | DOI:10.1155/2021/9955153 (Source: Neural Plasticity)
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Wenting Qin Anjing Zhang Mingzhen Yang Chan Chen Lijun Zhen Hong Yang Lingjing Jin Fang Li Source Type: research

Distinctive Gut Microbiota Alteration Is Associated with Poststroke Functional Recovery: Results from a Prospective Cohort Study
This study was designed to explore the poststroke alterations of gut microbiota and potential correlations between gut microbiota and global functions.METHODS: A total of thirty-eight patients with stroke and thirty-five healthy demographics-matched controls were recruited. Their fecal DNAs were extracted, and the V3-V4 regions of the conserved bacterial 16S RNA were amplified and sequenced on the Illumina MiSeq platform. Microbial composition, diversity indices, and species cooccurrence were compared between groups. Random forest and receiver operating characteristic analysis were used to identify potential diagnostic bio...
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Yini Dang Xintong Zhang Yu Zheng Binbin Yu Dijia Pan Xiaomin Jiang Chengjie Yan Qiuyu Yu Xiao Lu Source Type: research

Sports Augmented Cognitive Benefits: An fMRI Study of Executive Function with Go/NoGo Task
This study explores the effect of dynamic neural network processing with the classic Go/NoGo task with regular exercisers. We used functional magnetic resonance imaging to analyze the brain activation of areas involved in executive function, especially inhibitory control. Nineteen regular joggers and twenty-one subjects as a control group performed the task, and their brain imaging data were analyzed. The results showed that at the attentive visual period, the frontal and parietal areas, including the prefrontal cortex, putamen, thalamus, lingual, fusiform, and caudate, were significantly enhanced in positive activities th...
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Qingguo Ding Lina Huang Jie Chen Farzaneh Dehghani Juan Du Yingli Li Qin Li Hongqiang Zhang Zhen Qian Wenbin Shen Xiaowei Yin Pei Liang Source Type: research

Soleus H-Reflex Change in Poststroke Spasticity: Modulation due to Body Position
CONCLUSIONS: The motor neuron excitability of both sides was not suppressed but instead upregulated in the standing position in subjects with spasticity, which may suggest that there was abnormal regulation of the Ia pathway on both sides.PMID:34917144 | PMC:PMC8670919 | DOI:10.1155/2021/9955153 (Source: Neural Plasticity)
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Wenting Qin Anjing Zhang Mingzhen Yang Chan Chen Lijun Zhen Hong Yang Lingjing Jin Fang Li Source Type: research

Distinctive Gut Microbiota Alteration Is Associated with Poststroke Functional Recovery: Results from a Prospective Cohort Study
This study was designed to explore the poststroke alterations of gut microbiota and potential correlations between gut microbiota and global functions.METHODS: A total of thirty-eight patients with stroke and thirty-five healthy demographics-matched controls were recruited. Their fecal DNAs were extracted, and the V3-V4 regions of the conserved bacterial 16S RNA were amplified and sequenced on the Illumina MiSeq platform. Microbial composition, diversity indices, and species cooccurrence were compared between groups. Random forest and receiver operating characteristic analysis were used to identify potential diagnostic bio...
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Yini Dang Xintong Zhang Yu Zheng Binbin Yu Dijia Pan Xiaomin Jiang Chengjie Yan Qiuyu Yu Xiao Lu Source Type: research

Sports Augmented Cognitive Benefits: An fMRI Study of Executive Function with Go/NoGo Task
This study explores the effect of dynamic neural network processing with the classic Go/NoGo task with regular exercisers. We used functional magnetic resonance imaging to analyze the brain activation of areas involved in executive function, especially inhibitory control. Nineteen regular joggers and twenty-one subjects as a control group performed the task, and their brain imaging data were analyzed. The results showed that at the attentive visual period, the frontal and parietal areas, including the prefrontal cortex, putamen, thalamus, lingual, fusiform, and caudate, were significantly enhanced in positive activities th...
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Qingguo Ding Lina Huang Jie Chen Farzaneh Dehghani Juan Du Yingli Li Qin Li Hongqiang Zhang Zhen Qian Wenbin Shen Xiaowei Yin Pei Liang Source Type: research

Soleus H-Reflex Change in Poststroke Spasticity: Modulation due to Body Position
CONCLUSIONS: The motor neuron excitability of both sides was not suppressed but instead upregulated in the standing position in subjects with spasticity, which may suggest that there was abnormal regulation of the Ia pathway on both sides.PMID:34917144 | PMC:PMC8670919 | DOI:10.1155/2021/9955153 (Source: Neural Plasticity)
Source: Neural Plasticity - December 17, 2021 Category: Neurology Authors: Wenting Qin Anjing Zhang Mingzhen Yang Chan Chen Lijun Zhen Hong Yang Lingjing Jin Fang Li Source Type: research

Blood-Brain Barrier Overview: Structural and Functional Correlation
Neural Plast. 2021 Dec 6;2021:6564585. doi: 10.1155/2021/6564585. eCollection 2021.ABSTRACTThe blood-brain barrier (BBB) is a semipermeable and extremely selective system in the central nervous system of most vertebrates, that separates blood from the brain's extracellular fluid. It plays a vital role in regulating the transport of necessary materials for brain function, furthermore, protecting it from foreign substances in the blood that could damage it. In this review, we searched in Google Scholar, Pubmed, Web of Science, and Saudi Digital Library for the various cells and components that support the development and fun...
Source: Neural Plasticity - December 16, 2021 Category: Neurology Authors: Abeer Alahmari Source Type: research

Blood-Brain Barrier Overview: Structural and Functional Correlation
Neural Plast. 2021 Dec 6;2021:6564585. doi: 10.1155/2021/6564585. eCollection 2021.ABSTRACTThe blood-brain barrier (BBB) is a semipermeable and extremely selective system in the central nervous system of most vertebrates, that separates blood from the brain's extracellular fluid. It plays a vital role in regulating the transport of necessary materials for brain function, furthermore, protecting it from foreign substances in the blood that could damage it. In this review, we searched in Google Scholar, Pubmed, Web of Science, and Saudi Digital Library for the various cells and components that support the development and fun...
Source: Neural Plasticity - December 16, 2021 Category: Neurology Authors: Abeer Alahmari Source Type: research

Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampal Neuronal Apoptosis in Experimental Vascular Dementia Mice by Promoting GPR30 Expression
This study is aimed at investigating the potential roles of G protein-coupled estrogen receptor 1 (GPER, also known as GPR30) in the preventive effect of ginsenoside Rg1 against cognitive impairment and hippocampal cell apoptosis in experimental vascular dementia (VD) in mice. The effects of bilateral common carotid artery stenosis (BCAS) on GPR30 expression at mRNA level were evaluated. Thereafter, the BCAS mouse model was utilized to evaluate the protection of Rg1 (0.1, 1, 10 mg/kg, 14 days, ip). Spatial memory was evaluated by water Morris Maze 7 days post BCAS. After behavioral tests, neuronal apoptosis was detected by...
Source: Neural Plasticity - December 13, 2021 Category: Neurology Authors: Fengming Shen Juan Wang Feng Gao Jingji Wang Guoqi Zhu Source Type: research

Assessment of Cortical Plasticity in Schizophrenia by Transcranial Magnetic Stimulation
Neural Plast. 2021 Dec 2;2021:5585951. doi: 10.1155/2021/5585951. eCollection 2021.ABSTRACTNeural plasticity refers to the capability of the brain to modify its structure and/or function and organization in response to a changing environment. Evidence shows that disruption of neuronal plasticity and altered functional connectivity between distinct brain networks contribute significantly to the pathophysiological mechanisms of schizophrenia. Transcranial magnetic stimulation has emerged as a noninvasive brain stimulation tool that can be utilized to investigate cortical excitability with the aim of probing neural plasticity...
Source: Neural Plasticity - December 13, 2021 Category: Neurology Authors: Turki Abualait Sultan Alzahrani Ahmed AlOthman Fahad Abdulah Alhargan Nouf Altwaijri Rooa Khallaf Eman Nasim Shahid Bashir Source Type: research

Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampal Neuronal Apoptosis in Experimental Vascular Dementia Mice by Promoting GPR30 Expression
This study is aimed at investigating the potential roles of G protein-coupled estrogen receptor 1 (GPER, also known as GPR30) in the preventive effect of ginsenoside Rg1 against cognitive impairment and hippocampal cell apoptosis in experimental vascular dementia (VD) in mice. The effects of bilateral common carotid artery stenosis (BCAS) on GPR30 expression at mRNA level were evaluated. Thereafter, the BCAS mouse model was utilized to evaluate the protection of Rg1 (0.1, 1, 10 mg/kg, 14 days, ip). Spatial memory was evaluated by water Morris Maze 7 days post BCAS. After behavioral tests, neuronal apoptosis was detected by...
Source: Neural Plasticity - December 13, 2021 Category: Neurology Authors: Fengming Shen Juan Wang Feng Gao Jingji Wang Guoqi Zhu Source Type: research

Assessment of Cortical Plasticity in Schizophrenia by Transcranial Magnetic Stimulation
Neural Plast. 2021 Dec 2;2021:5585951. doi: 10.1155/2021/5585951. eCollection 2021.ABSTRACTNeural plasticity refers to the capability of the brain to modify its structure and/or function and organization in response to a changing environment. Evidence shows that disruption of neuronal plasticity and altered functional connectivity between distinct brain networks contribute significantly to the pathophysiological mechanisms of schizophrenia. Transcranial magnetic stimulation has emerged as a noninvasive brain stimulation tool that can be utilized to investigate cortical excitability with the aim of probing neural plasticity...
Source: Neural Plasticity - December 13, 2021 Category: Neurology Authors: Turki Abualait Sultan Alzahrani Ahmed AlOthman Fahad Abdulah Alhargan Nouf Altwaijri Rooa Khallaf Eman Nasim Shahid Bashir Source Type: research

Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampal Neuronal Apoptosis in Experimental Vascular Dementia Mice by Promoting GPR30 Expression
This study is aimed at investigating the potential roles of G protein-coupled estrogen receptor 1 (GPER, also known as GPR30) in the preventive effect of ginsenoside Rg1 against cognitive impairment and hippocampal cell apoptosis in experimental vascular dementia (VD) in mice. The effects of bilateral common carotid artery stenosis (BCAS) on GPR30 expression at mRNA level were evaluated. Thereafter, the BCAS mouse model was utilized to evaluate the protection of Rg1 (0.1, 1, 10 mg/kg, 14 days, ip). Spatial memory was evaluated by water Morris Maze 7 days post BCAS. After behavioral tests, neuronal apoptosis was detected by...
Source: Neural Plasticity - December 13, 2021 Category: Neurology Authors: Fengming Shen Juan Wang Feng Gao Jingji Wang Guoqi Zhu Source Type: research

Assessment of Cortical Plasticity in Schizophrenia by Transcranial Magnetic Stimulation
Neural Plast. 2021 Dec 2;2021:5585951. doi: 10.1155/2021/5585951. eCollection 2021.ABSTRACTNeural plasticity refers to the capability of the brain to modify its structure and/or function and organization in response to a changing environment. Evidence shows that disruption of neuronal plasticity and altered functional connectivity between distinct brain networks contribute significantly to the pathophysiological mechanisms of schizophrenia. Transcranial magnetic stimulation has emerged as a noninvasive brain stimulation tool that can be utilized to investigate cortical excitability with the aim of probing neural plasticity...
Source: Neural Plasticity - December 13, 2021 Category: Neurology Authors: Turki Abualait Sultan Alzahrani Ahmed AlOthman Fahad Abdulah Alhargan Nouf Altwaijri Rooa Khallaf Eman Nasim Shahid Bashir Source Type: research

Deep Sequencing of the Rat MCAO Cortexes Reveals Crucial circRNAs Involved in Early Stroke Events and Their Regulatory Networks
Neural Plast. 2021 Nov 24;2021:9942537. doi: 10.1155/2021/9942537. eCollection 2021.ABSTRACTCircular RNAs (circRNAs) are highly enriched in the central nervous system and significantly involved in a range of brain-related physiological and pathological processes. Ischemic stroke is a complex disorder caused by multiple factors; however, whether brain-derived circRNAs participate in the complex regulatory networks involved in stroke pathogenesis remains unknown. Here, we successfully constructed a cerebral ischemia-injury model of middle cerebral artery occlusion (MCAO) in male Sprague-Dawley rats. Preliminary qualitative a...
Source: Neural Plasticity - December 6, 2021 Category: Neurology Authors: Chengtan Wang Yuying Yang Mengsi Xu Fuxiu Mao Peng Yang Shan Yuan Rui Gao Shangquan Gan Source Type: research

Deep Sequencing of the Rat MCAO Cortexes Reveals Crucial circRNAs Involved in Early Stroke Events and Their Regulatory Networks
Neural Plast. 2021 Nov 24;2021:9942537. doi: 10.1155/2021/9942537. eCollection 2021.ABSTRACTCircular RNAs (circRNAs) are highly enriched in the central nervous system and significantly involved in a range of brain-related physiological and pathological processes. Ischemic stroke is a complex disorder caused by multiple factors; however, whether brain-derived circRNAs participate in the complex regulatory networks involved in stroke pathogenesis remains unknown. Here, we successfully constructed a cerebral ischemia-injury model of middle cerebral artery occlusion (MCAO) in male Sprague-Dawley rats. Preliminary qualitative a...
Source: Neural Plasticity - December 6, 2021 Category: Neurology Authors: Chengtan Wang Yuying Yang Mengsi Xu Fuxiu Mao Peng Yang Shan Yuan Rui Gao Shangquan Gan Source Type: research

Deep Sequencing of the Rat MCAO Cortexes Reveals Crucial circRNAs Involved in Early Stroke Events and Their Regulatory Networks
Neural Plast. 2021 Nov 24;2021:9942537. doi: 10.1155/2021/9942537. eCollection 2021.ABSTRACTCircular RNAs (circRNAs) are highly enriched in the central nervous system and significantly involved in a range of brain-related physiological and pathological processes. Ischemic stroke is a complex disorder caused by multiple factors; however, whether brain-derived circRNAs participate in the complex regulatory networks involved in stroke pathogenesis remains unknown. Here, we successfully constructed a cerebral ischemia-injury model of middle cerebral artery occlusion (MCAO) in male Sprague-Dawley rats. Preliminary qualitative a...
Source: Neural Plasticity - December 6, 2021 Category: Neurology Authors: Chengtan Wang Yuying Yang Mengsi Xu Fuxiu Mao Peng Yang Shan Yuan Rui Gao Shangquan Gan Source Type: research