Filtered By:
Specialty: Neuroscience
Education: Learning

This page shows you your search results in order of relevance. This is page number 2.

Order by Relevance | Date

Total 286 results found since Jan 2013.

The Allure of Big Data to Improve Stroke Outcomes: Review of Current Literature
AbstractPurpose of ReviewTo critically appraise literature on recent advances and methods using “big data” to evaluate stroke outcomes and associated factors.Recent FindingsRecent big data studies provided new evidence on the incidence of stroke outcomes, and important emerging predictors of these outcomes. Main highlights included the identification of COVID-19 infection and exposure to a low-dose particulate matter as emerging predictors of mortality post-stroke. Demographic (age, sex) and geographical (rural vs. urban) disparities in outcomes were also identified. There was a surge in methodological (e.g., machine l...
Source: Current Neurology and Neuroscience Reports - March 11, 2022 Category: Neuroscience Source Type: research

IS 12. Plasticity in stroke patients: Why brain stimulation may (not) work
Advances in brain imaging techniques allow us to study not just what the brain looks like but how it works. When applied to people who have suffered a stroke this technology has demonstrated reorganization of the way surviving brain regions function. These findings give hope to the idea that new treatments can be designed and more effectively targeted towards individual patients.So how can we measure these changes in organization in the human brain? Brain imaging techniques such as functional magnetic resonance imaging (fMRI) have developed to the point where a detailed appreciation of the damage to brain structures and th...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: N. Ward Tags: Society Proceedings Source Type: research

Comorbid Aβ toxicity and stroke: hippocampal atrophy, pathology, and cognitive deficit
Abstract: Numerous clinical and epidemiological reports indicate that patients with history of vascular illness such as stroke are more likely to develop dementia as the clinical manifestation of Alzheimer's disease. However, there are little data regarding the pathologic mechanisms that link vascular risk factors to the factors associated with dementia onset. We provide evidence that suggests intriguing detrimental interactions between stroke and β-amyloid (Aβ) toxicity in the hippocampus. Stroke was induced by unilateral striatal injection of endothelin-1, the potent vasoconstrictor. Aβ toxicity was modeled by bilater...
Source: Neurobiology of Aging - January 10, 2014 Category: Neuroscience Authors: Zareen Amtul, Simona Nikolova, Lulu Gao, Robin J. Keeley, John F. Bechberger, Alicia L. Fisher, Robert Bartha, David G. Munoz, Robert J. McDonald, Christian C. Naus, J. Martin Wojtowicz, Vladimir Hachinski, David F. Cechetto Tags: Regular Articles Source Type: research

The presence of a single-nucleotide polymorphism in the BDNF gene affects the rate of locomotor adaptation after stroke.
Abstract Induction of neural plasticity through motor learning has been demonstrated in animals and humans. Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family of growth factors, is thought to play an integral role in modulation of central nervous system plasticity during learning and motor skill recovery. Thirty percent of humans possess a single-nucleotide polymorphism on the BDNF gene (Val66Met), which has been linked to decreased activity-dependent release of BDNF. Presence of the polymorphism has been associated with altered cortical activation, short-term plasticity and altered skil...
Source: Experimental Brain Research - October 20, 2015 Category: Neuroscience Authors: Helm EE, Tyrell CM, Pohlig RT, Brady LD, Reisman DS Tags: Exp Brain Res Source Type: research

Piloting a Sex-Specific, Technology-Enhanced, Active Learning Intervention for Stroke Prevention in Women
ABSTRACT: Background: Recent studies reveal deficiencies in stroke awareness and knowledge of risk factors among women. Existing stroke education interventions may not address common and sex-specific risk factors in the population with the highest stroke-related rate of mortality. Objective: This pilot study assessed the efficacy of a technology-enhanced, sex-specific educational program (“SISTERS”) for women’s knowledge of stroke. Methods: This was an experimental pretest-posttest design. The sample consisted of 150 women (mean age, 55 years) with at least 1 stroke risk factor. Participants were randomized to either...
Source: Journal of Neuroscience Nursing - November 8, 2017 Category: Neuroscience Tags: Article Source Type: research

An RFID-based activity tracking system to monitor individual rodent behavior in environmental enrichment: Implications for post-stroke cognitive recovery
ConclusionThis study represents an attempt to better align preclinical and clinical implementations of EE and facilitate the uptake of this intervention in the clinical setting.
Source: Journal of Neuroscience Methods - May 30, 2019 Category: Neuroscience Source Type: research

Motor Performance But Neither Motor Learning Nor Motor Consolidation Are Impaired in Chronic Cerebellar Stroke Patients.
Abstract The capacity to acquire and retain new motor skills is essential for everyday behavior and a prerequisite to regain functional independence following impairments of motor function caused by brain damage, e.g., ischemic stroke. Learning a new motor skill requires repeated skill practice and passes through different online and offline learning stages that are mediated by specific dynamic interactions between distributed brain regions including the cerebellum. Motor sequence learning is an extensively studied paradigm of motor skill learning, yet the role of the cerebellum during online and offline stages re...
Source: Cerebellum - January 29, 2020 Category: Neuroscience Authors: Hermsdorf F, Fricke C, Stockert A, Classen J, Rumpf JJ Tags: Cerebellum Source Type: research

Intermittent Cerebellar Theta Burst Stimulation Improves Visuo-motor Learning in Stroke Patients: a Pilot Study.
In this study, we investigated the effects of cerebellar intermittent theta burst stimulation (c-iTBS), a high-frequency rTMS protocol, on visuo-motor learning in a sample of hemiparetic patients due to recent stroke in the territory of the contralateral middle cerebral artery. Eight stroke patients were enrolled for the purposes of the study in the chronic stage of recovery (i.e., at least 6 months after stroke). In two sessions, Patients were randomly assigned to treatment with real or sham c-iTBS applied over the cerebellar hemisphere ipsilateral to the affected body side. c-iTBS was applied immediately before the lea...
Source: Cerebellum - May 27, 2020 Category: Neuroscience Authors: Bonnì S, Motta C, Pellicciari MC, Casula EP, Cinnera AM, Maiella M, Picazio S, Tramontano M, Sallustio F, Koch G Tags: Cerebellum Source Type: research

Explicit motor sequence learning after stroke: a neuropsychological study
Exp Brain Res. 2021 Jun 5. doi: 10.1007/s00221-021-06141-5. Online ahead of print.ABSTRACTMotor learning interacts with and shapes experience-dependent cerebral plasticity. In stroke patients with paresis of the upper limb, motor recovery was proposed to reflect a process of re-learning the lost/impaired skill, which interacts with rehabilitation. However, to what extent stroke patients with hemiparesis may retain the ability of learning with their affected limb remains an unsolved issue, that was addressed by this study. Nineteen patients, with a cerebrovascular lesion affecting the right or the left hemisphere, underwent...
Source: Experimental Brain Research - June 6, 2021 Category: Neuroscience Authors: Cristina Russo Laura Veronelli Carlotta Casati Alessia Monti Laura Perucca Francesco Ferraro Massimo Corbo Giuseppe Vallar Nadia Bolognini Source Type: research

Ipsilesional Mu Rhythm Desynchronization Correlates With Improvements in Affected Hand Grip Strength and Functional Connectivity in Sensorimotor Cortices Following BCI-FES Intervention for Upper Extremity in Stroke Survivors
Stroke is a leading cause of acquired long-term upper extremity motor disability. Current standard of care trajectories fail to deliver sufficient motor rehabilitation to stroke survivors. Recent research suggests that use of brain-computer interface (BCI) devices improves motor function in stroke survivors, regardless of stroke severity and chronicity, and may induce and/or facilitate neuroplastic changes associated with motor rehabilitation. The present sub analyses of ongoing crossover-controlled trial NCT02098265 examine first whether, during movements of the affected hand compared to rest, ipsilesional Mu rhythm desyn...
Source: Frontiers in Human Neuroscience - October 28, 2021 Category: Neuroscience Source Type: research

Is Matrix Metalloproteinase-9 Associated with Post-Stroke Cognitive Impairment or Dementia?
CONCLUSIONS: MMP-9 level and MMP-9 rs3918242 polymorphism have an important role in the occurrence and development of post-stroke cognitive impairment or dementia (PSCID).PMID:36424752 | DOI:10.31083/j.jin2106160
Source: Journal of Integrative Neuroscience - November 25, 2022 Category: Neuroscience Authors: Jianhua Zhao Fangli Yang Xue Peng Qing Li Fan Wang Zhixiu Xu Ruiyan Cai Danxia Ji Jian Zhang Minghua Wang Qiong Li Sibei Ji Shaomin Li Source Type: research