Filtered By:
Education: Study
Nutrition: Calcium

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 866 results found since Jan 2013.

Revised Framingham Stroke Risk Score, Nontraditional Risk Markers, and Incident Stroke in a Multiethnic Cohort Clinical Sciences
Conclusions—The R-FSRS downgraded stroke risk but had better calibration and discriminative ability for incident stroke compared with the original FSRS. Nontraditional risk markers modestly improved the discriminative ability of the R-FSRS, with coronary artery calcium performing the best.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Peter Flueckiger, Will Longstreth, David Herrington, Joseph Yeboah Tags: Epidemiology, Primary Prevention, Race and Ethnicity, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Neuroimaging, serum biomarkers, and patient characteristics as predictors of upper limb functioning 12 weeks after acute stroke: an observational, prospective study.
CONCLUSION: ASPECTS score ≥ 8 within 24 hours and S100β protein < 140.5 ng/L at 48 hours predict better upper limb functioning, while advanced age predicts worse upper limb functioning 12 weeks after stroke. PMID: 30213243 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 13, 2018 Category: Neurology Authors: Branco JP, Oliveira S, Sargento-Freitas J, Galego O, Cordeiro G, Cunha L, Freire Gonçalves A, Pinheiro J Tags: Top Stroke Rehabil Source Type: research

Factors Influencing Quality of Life in Stroke Patients: Focus on Eating Habits
This study aimed to identify lifestyle factors about eating habits that may affect the quality of life (QOL) in elderly stroke patients. Methods: Fifty elderly patients with a first-ever stroke were enrolled. QOL was assessed by the Stroke and Aphasia QOL Scale-39-J. Lifestyle factors about eating habits were collected using questionnaires (Questions 1-17) for the intake of salt, calcium, magnesium, potassium, taurine, fiber, and protein, and the frequency of breakfast.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2019 Category: Neurology Authors: Reina Chiba, Saya Tominaga, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Toshiko Tomisawa, Junko Chiba, Joji Hagii, Minoru Yasujima, Tomohiro Osanai Source Type: research

Human Milk Oligosaccharide 2 ′-Fucosyllactose Reduces Neurodegeneration in Stroke Brain
In conclusion, our data suggest that 2’-FL has neuroprotective action through inhibition of Ca++i, inflammation, and apoptosis. Posttreatment with 2 ’-FL facilitates neural repair in stroke brain.
Source: Translational Stroke Research - January 1, 2020 Category: Neurology Source Type: research

Calcium Channel Subunit α2δ-1 as a Potential Biomarker Reflecting Illness Severity and Neuroinflammation in Patients with Acute Ischemic Stroke
Cerebral infarction (commonly known as ischemic stroke) is a leading cause of morbidity, mortality and disability worldwide. Activation of presynaptic voltage-gated calcium channels (VGCCs) and glutamate release plays a central role in neuronal necrosis after cerebral ischemia.1,2 Previous studies seemed to be encouraging that nimodipine, a dihydropyridine calcium channel antagonist, had a significant benefit in mortality and neurologic outcome in patients with mild stroke or within 12 hours of stroke, although there was still controversial.
Source: Journal of Stroke and Cerebrovascular Diseases - May 25, 2021 Category: Neurology Authors: Xiaoqin Xiong, Linjing Zhang, Yunhui Li, Shuang Guo, Wei Chen, Lijun Huang, Yi Luo Source Type: research

Gut Microbiota in Ischemic Stroke: Role of Gut Bacteria-Derived Metabolites
AbstractIschemic stroke (IS) remains a leading cause of death and long-term disability globally. Several mechanisms including glutamate excitotoxicity, calcium overload, neuroinflammation, oxidative stress, mitochondrial damage, and apoptosis are known to be involved in the pathogenesis of IS, but the underlying pathophysiology mechanisms of IS are not fully clarified. During the past decade, gut microbiota were recognized as a key regulator to affect the health of the host either directly or via their metabolites. Recent studies indicate that gut bacterial dysbiosis is closely related to hypertension, diabetes, obesity, d...
Source: Translational Stroke Research - October 24, 2022 Category: Neurology Source Type: research

Effect of Inflammation on the Process of Stroke Rehabilitation and Poststroke Depression
Conclusions Stroke comprises ischemic stroke and ICH. The immuno-inflammatory process is involved in neural plasticity following events such as a hemorrhage or ischemic stroke. After ischemia, astrocytes, microglia, and MDMs play important roles during rehabilitation with the modulation of cytokines or chemokines, such as TNF-α and IL-1. Moreover, MiRNAs are also important posttranscriptional regulators in these glial mitochondrial responses to cerebral ischemia. ICH involves processes similar and different to those seen in ischemia, including neuronal injury, astrocytic and microglial/macrophage activation, and n...
Source: Frontiers in Psychiatry - April 10, 2019 Category: Psychiatry Source Type: research

Postreperfusion Blood Pressure Variability After Endovascular Thrombectomy Affects Outcomes in Acute Ischemic Stroke Patients With Poor Collateral Circulation
Conclusion: Postreperfusion BP management by decreasing BPV may have influence on improving clinical outcome in cases of poor collateral circulation among patients achieving successful recanalization after ERT. Introduction Endovascular recanalization therapy (ERT) has been adopted as standard stroke care in patients with acute ischemic stroke (1–6). Time to recanalization and degree of recanalization are the most important predictors of clinical outcomes after ERT (7). Before recanalization, an effort to reduce the time from symptom onset to reperfusion is critical for penumbral salvage. After recanalization...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research

Using Dental Pulp Stem Cells for Stroke Therapy
Conclusion and Future Perspectives Stem cell-based therapy is a promising alternative for stroke treatment. While stem cells from different sources, including induced PSC, ESC, MSC, and NSC, have been investigated, using NSC and enhancing the natural mechanisms is most appropriate for brain repair. In preclinical models of stroke, stem cell transplantation has led to positive outcomes through a variety of cellular and molecular mechanisms, many being mediated by the array of beneficial factors produced by the cells. Recent advances in cellular reprogramming have provided alternative sources of NSC to be investigated, allo...
Source: Frontiers in Neurology - April 28, 2019 Category: Neurology Source Type: research

1H NMR-Based Metabolomics Reveals Refined-Huang-Lian-Jie-Du-Decoction (BBG) as a Potential Ischemic Stroke Treatment Drug With Efficacy and a Favorable Therapeutic Window
This study was carried out in accordance with the recommendations of Animal Ethics Committee of China Pharmaceutical University. The protocol was approved by Animal Ethics Committee of China Pharmaceutical University. Author Contributions JW, MY, and LK conceived the experiments and helped to coordinate support and funding. XF performed the research and drafted the manuscript. SL, YL, and DX participated in the experiments. JW analyzed the data and edited the paper. All authors read and approved the final manuscript. Conflict of Interest Statement The authors declare that the research was conducted in the absence of an...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research

Shengui Sansheng San Ameliorates Cerebral Energy Deficiency via Citrate Cycle After Ischemic Stroke
Conclusion In summary, SSS extraction significantly ameliorates cerebral energy metabolism via boosting citrate cycle, which mainly embodies the enhancements of blood glucose concentration, glucose and lactate transportation and glucose utilization, as well as the regulations of relative enzymes activities in citrate cycle. These ameliorations ultimately resulted in numerous ATP yield after stroke, which improved neurological function and infarcted volume. Collectively, it suggests that SSS extraction has exerted advantageous effect in the treatment of cerebral ischemia. Ethics Statement All animal operations were accor...
Source: Frontiers in Pharmacology - April 22, 2019 Category: Drugs & Pharmacology Source Type: research

How People With Diabetes Can Lower Stroke Risk
After spending nearly two decades trying to manage her Type 2 diabetes, Agnes Czuchlewski landed in the emergency room in 2015, with news that she’d just experienced a heart attack. She also learned that she had metabolic syndrome, a cluster of conditions that includes diabetes but also brings higher risk of heart disease and stroke. “Because I needed to lose quite a bit of weight when I was first diagnosed, I was focused on the number I saw on the scale, and then on my blood-sugar numbers,” recalls Czuchlewski, 68, who lives in New York City. “I didn’t realize other numbers came into play, li...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Disease healthscienceclimate Source Type: news

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration
Conclusion The developed and validated method to quantify neurounina-1 in beagle dog plasma using LC-MS/MS presented sensitivity and selectivity, thus allowing the rapid and precise determination of the pharmacokinetics of this neuroprotective compound working in the low nanomolar range. Ethics Statement This study was carried out in accordance with the recommendations of the general ethical guidelines established by the Brazilian Society for Laboratory Animal Science (SBCAL). The protocol was approved by the Committee for Ethics in Animal Use – State University of Campinas (CEUA/UNICAMP, protocol n° 3340-...
Source: Frontiers in Pharmacology - April 24, 2019 Category: Drugs & Pharmacology Source Type: research

Calcium intake and the risk of stroke: an up-dated meta-analysis of prospective studies.
CONCLUSIONS: Dairy calcium intake is inversely associated with stroke incidence. There is a non-linear dose-response relationship between calcium intake and stroke risk. However, when the follow-up time is long enough, the inverse relationship is independent of dose. Additional large cohort studies are required to illustrate this relationship in detail. PMID: 26078241 [PubMed - in process]
Source: Asia Pacific Journal of Clinical Nutrition - June 18, 2015 Category: Nutrition Authors: Tian DY, Tian J, Shi CH, Song B, Wu J, Ji Y, Wang RH, Mao CY, Sun SL, Xu YM Tags: Asia Pac J Clin Nutr Source Type: research

Calcium supplements linked to post-stroke dementia in women
Conclusion The media paint this as a troubling study for older women who take calcium to strengthen their bones. However the small size of the study (only 98 women took calcium supplements, and only 14 of those got dementia) and its observational nature mean that we cannot rely on the results. As the researchers mention, it is possible that those taking supplements were less healthy than those that didn't in some unmeasured way. Further research may improve our confidence in these results. Broken bones are not a trivial matter for older people – a broken hip can be the difference between being able to live independentl...
Source: NHS News Feed - August 18, 2016 Category: Consumer Health News Tags: Neurology Medication Older people Source Type: news