Filtered By:
Education: Study
Nutrition: Calcium
This page shows you your search results in order of relevance. This is page number 19.
Order by Relevance | Date
Total 866 results found since Jan 2013.
Triiodothyronine Aggravates Global Cerebral Ischemia-Reperfusion Injury in Mice
In this study, we examined the effect of T3 administration on DNA fragmentation induced by neuronal death and the activation of inflammatory cells such as astrocytes and microglia in the hippocampus following GCI. The content of nucleosomes generated by DNA fragmentation in the hippocampus was increased by GCI and further increased by T3 administration. The protein expression levels of glial fibrillary acidic protein (GFAP), an astrocytic marker, and Ionized calcium binding adaptor protein 1 (Iba1), a microglial marker, in the hippocampus were also increased by GCI and further increased by T3 administration. The levels of ...
Source: Biological and Pharmaceutical Bulletin - December 2, 2021 Category: Drugs & Pharmacology Authors: Masaru Doshi Shiro Watanabe Yujin Natori Makoto Hosoyamada Yutaka Hirashima-Akae Source Type: research
Association Between 18-FDG Positron Emission Tomography and MRI Biomarkers of Plaque Vulnerability in Patients With Symptomatic Carotid Stenosis
Conclusion: This study demonstrated novel correlations of non-invasive imaging biomarkers of inflammation-related plaque metabolism with morphological MRI markers of plaque instability. If replicated, our findings may support the application of combined MRI and PET to detect vulnerable plaque in future clinical practise and randomised trials.
Source: Frontiers in Neurology - December 23, 2021 Category: Neurology Source Type: research
Triiodothyronine Aggravates Global Cerebral Ischemia-Reperfusion Injury in Mice
In this study, we examined the effect of T3 administration on DNA fragmentation induced by neuronal death and the activation of inflammatory cells such as astrocytes and microglia in the hippocampus following GCI. The content of nucleosomes generated by DNA fragmentation in the hippocampus was increased by GCI and further increased by T3 administration. The protein expression levels of glial fibrillary acidic protein (GFAP), an astrocytic marker, and Ionized calcium binding adaptor protein 1 (Iba1), a microglial marker, in the hippocampus were also increased by GCI and further increased by T3 administration. The levels of ...
Source: Biological and Pharmaceutical Bulletin - December 2, 2021 Category: Drugs & Pharmacology Authors: Masaru Doshi Shiro Watanabe Yujin Natori Makoto Hosoyamada Yutaka Hirashima-Akae Source Type: research
Neuroprotective effects of an < em > in vitro < /em > BBB permeable phenoxythiophene sulfonamide small molecule in glutamate-induced oxidative injury
Exp Ther Med. 2022 Jan;23(1):79. doi: 10.3892/etm.2021.11002. Epub 2021 Nov 25.ABSTRACTReactive oxygen species (ROS) play a central role in oxidative stress-associated neuronal cell death during ischemia. Further investigation into the inhibition of excessive ROS generation post-stroke is urgently required for the treatment of ischemic stroke. In the present study, the neuroprotective properties of the blood-brain barrier (BBB) penetrant B355227 were investigated. B355227 is a chemical analogue of B355252, and the role of the phenoxythiophene sulfonamide compound B355227 was further investigated in a glutamate-induced oxid...
Source: Experimental and Therapeutic Medicine - December 23, 2021 Category: General Medicine Authors: Smritee Pokharel Nailya S Gliyazova Srinivasa R Dandepally Alfred L Williams Gordon C Ibeanu Source Type: research
Infrared Spectroscopic Study and Mathematical Simulations of Carotid Atherosclerosis
CONCLUSION: Fourier-transform infrared spectroscopy and mathematical simulation models showed that carotid artery stenosis over 45% reduces the blood flow rate, while stenosis over 65% dramatically increases the hemodynamic disturbance, with a parallel increase the rate of ischemic stroke or other major adverse cardiovascular events.PMID:34972714 | DOI:10.21873/invivo.12690
Source: Atherosclerosis - January 1, 2022 Category: Cardiology Authors: Jane Anastassopoulou Vasiliki Mamareli Evangelos Mylonas Panagiota Kolovou Ioannis Mamarelis Christophoros Kotoulas Christina Mamareli Sotiris Kotoulas Emmanouil Koutoulakis Konstantinos Spiliopoulos Theophile Theophanides Source Type: research
