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Specialty: Endocrinology
Condition: Diabetes
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Total 1416 results found since Jan 2013.
Ezetimibe-Simvastatin Therapy Reduce Recurrent Ischemic Stroke Risks in Type 2 Diabetic Patients.
CONCLUSIONS: High potency lipid-lowering therapy effectively reduces the risk of recurrent IS in diabetic patients regardless of ATOR or EZ-SIM combination therapy.
PMID: 27270238 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - June 5, 2016 Category: Endocrinology Authors: Liu CH, Chen TH, Lin MS, Hung MJ, Chung CM, Cherng WJ, Lee TH, Lin YS Tags: J Clin Endocrinol Metab Source Type: research
Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study
CONCLUSIONS
Adults with both high TG and low HDL-C, particularly those with diabetes, have increased risks of incident CHD and stroke. In particular, those with an LDL-C level ≥130 mg/dL may have an increased risk of incident stroke.
Source: Diabetes Care - March 20, 2017 Category: Endocrinology Authors: Lee, J. S.; Chang, P.-Y.; Zhang, Y.; Kizer, J. R.; Best, L. G.; Howard, B. V. Tags: Epidemiology/Health Services Research Source Type: research
Sex Differences in Cardiovascular Risk Profiles of Ischemic Stroke Patients with Diabetes in the Greater Cincinnati/ Northern Kentucky Stroke Study
ConclusionsWomen with DM had strokes at a younger age, whereas no such age difference existed in men. As opposed to men, women with DM were also more likely to have CAD compared with those without DM, suggesting a sex difference in the association between DM and vascular disease. These findings may suggest a need for more aggressive risk factor management in diabetic women.
Source: Journal of Diabetes - May 1, 2017 Category: Endocrinology Authors: Tracy E. Madsen, Jane C. Khoury, Kathleen A. Alwell, Charles J. Moomaw, Stacie L. Demel, Matthew L. Flaherty, Daniel Woo, Jason Mackey, Felipe De Los Rios La Rosa, Sharyl Martini, Simona Ferioli, Opeolu Adeoye, Pooja Khatri, Brett M. Kissela, Dawn Kleindo Tags: Original Article Source Type: research
Dose-dependent effect of smoking on risk of coronary heart disease, heart failure and stroke in individuals with type 1 diabetes
Conclusions/interpretationThere is a dose-dependent association between smoking and cardiovascular disease in individuals with type 1 diabetes. In men in particular, the risk of incident stroke remains high even after smoking cessation and is increased in current and former smokers independently of other risk factors.
Source: Diabetologia - November 5, 2018 Category: Endocrinology Source Type: research
Incretin-Based Antihyperglycemic Agents for the Management of Acute Ischemic Stroke in Patients with Diabetes Mellitus: A Review
AbstractDiabetes mellitus (DM) is a major risk factor for ischemic stroke. Moreover, patients with DM suffer more severe strokes and have worse functional outcome following an acute stroke than patients without DM. In this context, data from animal studies and emerging evidence from clinical studies suggest that incretin-based antihyperglycemic agents might exert beneficial effects in patients with DM who suffer ischemic stroke. It appears that these agents exert neuroprotective actions that might both reduce infarct size and promote recovery. The present review summarizes the evidence on the potential role of incretin-bas...
Source: Diabetes Therapy - February 6, 2019 Category: Endocrinology Source Type: research
The association of serum lipid level with ischemic stroke in the elderly of Xinjiang.
CONCLUSION: An abnormal serum lipid level of the patients with IS in older Xinjiang population is significantly associated with the stroke subtypes, plaque stability, hypertension and diabetes.
PMID: 30927763 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - April 1, 2019 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research
Cardiovascular Outcomes of Vildagliptin in Patients with Type 2 Diabetes Mellitus after Acute Coronary Syndrome or Acute Ischemic Stroke
ConclusionsAmong patients with T2DM after a recent ACS or AIS, treatment with vildagliptin was not associated with increased risks of CV death, nonfatal MI, nonfatal stroke, and hospitalization for HF.This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - May 21, 2019 Category: Endocrinology Authors: Dong ‐Yi Chen,
Yan‐Rong Li,
Chun‐Tai Mao,
Chi‐Nan Tseng,
I‐Chang Hsieh,
Ming‐Jui Hung,
Pao‐Hsien Chu,
Chao‐Hung Wang,
Ming‐Shien Wen,
Wen‐Jin Cherng,
Tien‐Hsing Chen Tags: Original Article Source Type: research
Beneficial impact of intensified multifactorial intervention on risk of stroke: outcome of 21 years of follow-up in the randomised Steno-2 Study
Conclusions/interpretationIntensified multiple risk factor intervention in patients with type 2 diabetes and microalbuminuria reduces the risk for strokes as well as the number of recurrent cerebrovascular events.Trial registrationClinicalTrials.gov NCT00320008.
Source: Diabetologia - May 31, 2019 Category: Endocrinology Source Type: research
Cardiovascular Outcomes of Vildagliptin in Patients with Type 2 Diabetes Mellitus after Acute Coronary Syndrome or Acute Ischemic Stroke
ConclusionsAmong patients with T2DM after a recent ACS or AIS, treatment with vildagliptin was not associated with increased risks of CV death, nonfatal MI, nonfatal stroke, and hospitalization for HF.This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - May 21, 2019 Category: Endocrinology Authors: Dong ‐Yi Chen,
Yan‐Rong Li,
Chun‐Tai Mao,
Chi‐Nan Tseng,
I‐Chang Hsieh,
Ming‐Jui Hung,
Pao‐Hsien Chu,
Chao‐Hung Wang,
Ming‐Shien Wen,
Wen‐Jin Cherng,
Tien‐Hsing Chen Tags: Original Article Source Type: research
Prevention of myocardial infarction and stroke with PCSK9 inhibitors treatment: a metanalysis of recent randomized clinical trials
ConclusionsPCSK9 inhibitors reduce the incidence of myocardial infarction by 19% and stroke by 25%.
Source: Journal of Diabetes and Metabolic Disorders - May 31, 2020 Category: Endocrinology Source Type: research
The Relationship between Glucose Control & Cognitive Function in People with Diabetes after a Lacunar Stroke.
CONCLUSION: This analysis of lacunar stroke patients with diabetes demonstrates a relationship between A1C and change in cognitive scores over time. Intervention studies are needed in order to delineate if better glucose control could slow the rate of cognitive decline in this high risk population.
PMID: 33481011 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - January 22, 2021 Category: Endocrinology Authors: Cukierman-Yaffe T, McClure LA, Thomas R, Bosch J, Sharma M, Gerstein HC, Benavente O Tags: J Clin Endocrinol Metab Source Type: research
Metformin versus sulphonylureas for new onset atrial fibrillation and stroke in type 2 diabetes mellitus: a population-based study
ConclusionsSulphonylurea use was associated with higher risks of incident AF, stroke, cardiovascular mortality and all-cause mortality compared to metformin. Males and patients older than 65 years with sulphonylurea use were exposed to the highest risks.
Source: Acta Diabetologica - February 3, 2022 Category: Endocrinology Source Type: research
Do SGLT2 inhibitors and GLP-1 receptor agonists modulate differently the risk of stroke ? Discordance between randomised controlled trials and observational studies
Diabetes Metab. 2023 Sep 5:101474. doi: 10.1016/j.diabet.2023.101474. Online ahead of print.ABSTRACTStroke represents a major burden in patients with type 2 diabetes, yet this cerebrovascular complication has been less carefully investigated than the risk of cardiovascular mortality, heart failure and renal disease. Some data suggested that glucagon peptide-1 receptor agonists (GLP-1RAs) exert a better protection against stroke than sodium-glucose cotransporter 2 inhibitors (SGLT2is). However, this conclusion was derived from indirect comparisons in absence of any head-to-head randomised controlled trial (RCT). The present...
Source: Diabetes and Metabolism - September 7, 2023 Category: Endocrinology Authors: Andr é J Scheen Source Type: research
