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Search for relevant indications for selenium supplementation in thyroid diseases.
Authors: Wojciechowska-Durczynska K, Lewinski A Abstract Selenium plays a significant role in the thyroid function and its deficiency is considered by some authors to be a cause of thyroid disorders. The potential therapeutic influence of selenium supplementation in thyroid disease was investigated in several studies and some results were encouraging, however results were inconsistent and did not allow conclusion to be drawn. For that reason, we have performed a review study on relevance of selenium supplementation in thyroid disease. Till now, there is no strong evidence that selenium supplementation leads to clin...
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption.
We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia. We performed thyroxine absorption tests to diagnose the malabsorption and to evaluate the best therapeutic intervention. Once assessed a correct therapy lowering TSH, we observed the regression of pituitary mass confirming our diagnosis of secondary pituitary hyperplasia. We suggest to evaluate any possible reason for thyroxine malabsorption and to consider the hypothesis of pituitary hyperplasia in the presence of pituitary mass together with overt hypothyroidism. ...
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Unusual presentations of Carney Complex in patient with a novel PRKAR1A mutation.
Authors: Akin S, Noyan S, Dagdelen S, Pasaoglu I, Kaynaroglu V, Askun MM, Bilen CY, Kiratli H, Baydar DE, Onder S, Sokmensuer C, Aytemir K, Erkin G, Kiratli PO, Alikasifoglu M, Erbas T Abstract Carney Complex (CNC) is a multiple neoplasia syndrome characterized by skin tumors and pigmented lesions, myxomas, and various endocrine tumors. The aim of this case report was to describe a case of CNC with a novel PRKAR1A mutation. A man aged 46 years with a medical history of surgery for cardiac myxomas at the age of 39 was admitted to our hospital because of four newly-developed heart masses. The histologic examination c...
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Importance of education in the prevention of diabetic foot syndrome.
Authors: Pokorna J Abstract To the Editor, Diabetic foot syndrome (DFS) is defined by the WHO as ulceration or destruction of foot tissue in diabetic patients associated with neuropathy, with different degrees of the disease existing and frequently also with infection. The statistics are frightening: more than million amputations are annually carried out worldwide due to diabetic foot (Foster and Lauver 2014) and these amputations represent as far as 70% of all non-traumatic amputations. In 2013, 861 647 patients were treated for diabetes mellitus in Czech Republic, including 44 657 patients with diabetic foot...
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Analysis of the rs13306560 functional variant in the promoter region of the MTHFR gene in sporadic Parkinson ´s disease.
CONCLUSION: Although further studies are needed, our data suggest an important role of the MTHFR gene variants in the fine-tuning regulation of one-carbon metabolism in the brain. PMID: 28871711 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Some quantitative EEG features in default mode resting state network under general anaesthesia.
CONCLUSION: The functional connectivity in the DMRSN could be a reliable and robust method for assessing the depth of anaesthesia and maybe also disorders of consciousness in general. The mean squared coherences in the gamma frequency band indicated the highest sensitivity for the depth of unconsciousness. The measure is not dependent on the diffused slowing in dementia or encephalopathy patients as long as they remain in a full consciousness. PMID: 28871712 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Cognitive functions and serum cortisol concentration in perimenopausal and postmenopausal women working non-manually.
CONCLUSION: Higher serum cortisol concentration may negatively effect cognitive functions in women post menopause. PMID: 28871713 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Borderline personality disorder and unmet needs.
CONCLUSION: Observing the patients' needs may be essential to the treatment of the individuals suffering from BPD. However, many needs remain unmet in the areas linked to medical, personal, and social factors. A bigger focus on the patients' needs could be beneficial and should be targeted in the treatment. PMID: 28871714 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Personality as significant predictor of post-stroke anxiety.
CONCLUSION: Anxiety in stroke patients is predicted mostly by the personality traits and young age of patients. Knowing these predictors can result in early detection and management of emotional consequences of disease, and thus influence the whole recovery process. PMID: 28871715 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

The influence of Eruca sativa (Arugula) on pharmacokinetics of Sildenafil in rats.
CONCLUSION: Pre-administration of Eruca sativa has increased Sildenafil Cmax from 226.72 to 345.25 ng/ml, (p
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Acromegaly determination using discriminant analysis of the three-dimensional facial classification in Taiwanese.
CONCLUSION: The discriminant functions of detection developed in this study could help patients, their families, medical practitioners and others to identify and track progressive facial change patterns before the possible patients go to the hospital, especially the lateral "angles" which can be calculated by relative point-to-point changes derived from 2D lateral imagery without the 3D anthropometric measurements. This study tries to provide a novel and easy method to detect acromegaly when the patients start to have awareness of abnormal appearance because of facial measurement changes, and it also suggests tha...
Source: Neuroendocrinology Letters - September 7, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Mutations in AXIN2 gene as a risk factor for tooth agenesis and cancer: A review.
Authors: Abstract AXIN2 gene plays a crucial role in morphogenesis of craniofacial area and is essential for tooth development. AXIN2 gene is one of the most studied genes associated with tooth agenesis, the most common defect of dentition in humans. Polymorphic variants in AXIN2 gene are discussed in relation to the occurrence of the tooth agenesis but also as an indication of the risk of cancer. Mutations in AXIN2 gene were found in patients with colorectal or hepatocellular carcinoma, prostate cancer, ovarium or lung cancer. These findings support the hypothesis that missing teeth may be a significant marker fo...
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Neonatal Marfan syndrome: Report of two cases.
Authors: Abstract Marfan syndrome is rarely diagnosed in the neonatal period because of variable expression and age-dependent appearance of clinical signs. The prognosis is usually poor due to high probability of congestive heart failure, mitral and tricuspid regurgitations with suboptimal response to medical therapy and difficulties in surgical management. The authors have studied two cases of Marfan syndrome in the newborn period. Two cases of neonatal Marfan syndrome, one male and one female, were diagnosed by characteristic physical appearance. Both infants had significant cardiovascular abnormalities diagnose...
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Central hypoadrenocorticism associated with Rathke's cleft cyst.
In conclusion, the symptoms and endocrinological data for dysfunction of the hypothalamic pituitary system might be non-specific and vary among patients, especially in teenagers. Brain MRI and daily cortisol profiling in blood are key to obtaining a diagnosis of an impaired hypothalamic adrenal function due to RCC. PMID: 28759180 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Cognitive function and depressivity before and after cpap treatment in obstructive sleep apnea patients.
CONCLUSIONS: According to our results, the patients with sleep apnoea improved their mood and cognitive functions during the treatment by the CPAP device. PMID: 28759181 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Intima media thickness of common carotids and abdominal aorta in children and adolescents with congenital adrenal hyperplasia due to 21-hydroxylase deficiency in relation to their genotypes.
CONCLUSION: In CAH patients CIMT and AIMT are influenced by androgens and obesity independent. In the examined group vascular and metabolic abnormalities are pronounced more in certain subgroups of CAH (SV and SW: Del/Del) and in patients with advanced bone age. PMID: 28759182 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Co-administration of Cyclosporin A and Ondansetron decreases transient local cerebral ischemic injury in the mouse.
CONCLUSION: Overall, our study showed that a combination of cyclosporin A and ondansetron may be a practical clinical method to treat brain infarction. However, further studies are required to investigate the cerebroprotective mechanism of action, the possible side effects of co-administration of these drugs, and the ability of these ligands to cross the blood brain barrier. PMID: 28759183 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Is non-pharmacological treatment an effective option for chronic low back pain?
CONCLUSION: Non-pharmacological therapy of chronic non-malignant low back pain could be an effective option offered in combination with medicaments and change of lifestyle. PMID: 28759184 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Serum FGF21 in girls with anorexia nervosa - comparison to normal weight and obese female adolescents.
CONCLUSIONS: 1) Serum FGF21 concentrations are decreased in AN and elevated in obesity. They are independently and positively related to BMI and insulin resistance; 2) Decreased serum FGF21 in AN may support the maintenance of normal blood glucose through adjustment the insulin levels and insulin sensitivity; 3) Elevated FGF21 levels in obesity may be considered adaptive mechanism preventing insulin resistance and its metabolic consequences. PMID: 28759185 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Endocrine and haemodynamic stress responses to an arithmetic cognitive challenge.
Authors: Abstract OBJECTIVE: We aimed at developing and validating a simple, highly repeatable computer-based tool, which could be employed to simulate the effects of an acute mental stress on endocrine and haemodynamic stress responses. METHODS: Fifteen subjects underwent a mental cognitive challenge, employing an ad hoc designed web tool (available at http://bagame.altervista.org) that proposed a series of random arithmetic operations (addictions or subtractions) between one- to three-digit numbers for 10 minutes. We measured plasma epinephrine, norepinephrine, cortisol, and ACTH, in addition to heart rate (...
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

A Chinese herbal medicine (Modified Guomin Decoction) Influences the differentiation of CD4+ T-cell subsets in OVA-induced asthmatic mice.
Authors: Abstract OBJECTIVE: Modified Guomin Decoction (MGD) is an effective Chinese herbal medicine for treatment of various allergic diseases, especially allergic asthma. Its water decoction is conventionally used for treatment of allergic bronchitis in China. Up to date, the underlying mechanisms of this herbal combination have not been fully investigated yet. METHODS: In the in vivo study, the mice were treated with Chicken egg ovalbumin (OVA) and aluminum hydroxide gel as the classic allergic asthma animal model. After treatment with MGD, the lung tissues were examined by Histological assessment. The flow...
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Selected mechanical paremeters of women's hair in the Caucasian population.
CONCLUSION: By measuring 886 samples from the heads of 60 adult women of European type, it was possible to ascertain the current norm for a larger number of mechanical parameters of the hairs. Further merit of this work is the fact that the hairs were taken systematically from five well-defined places of the studied heads in equal count, which is an aspect formerly published works do not respect and they do not present the location of sampling. PMID: 28759188 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Carotid intima-media thickness in plaque-free area, carotid plaque and risk of ischemic stroke in high-risk population of North China.
CONCLUSION: Screening of carotid artery especially for carotid artery plaques should be taken into consideration among people with high risk of ischemic stroke. PMID: 28759189 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Genetic polymorphisms and serum concentrations of adiponectin and resistin in anorexia nervosa and healthy controls - pilot study.
CONCLUSION: Differences in genotype frequencies of ADIPOQ c.276 and RETN c.-180 suggest a need for studies on a larger cohort of patients with AN. PMID: 28759190 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Effects of age on the glucoregulatory response following acute glucoprivation induced by 2-deoxyglucose (2DG) in the adrenal medulla of Sprague Dawley rats.
CONCLUSION: The present findings also suggest that, at least in rats, aging alters the protein expression of the biosynthetic catecholamine enzymes as well as protein kinase substrates that may attenuate the response to glucoprivation. PMID: 28759191 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Anti-Mullerian hormone - a marker of upcoming menopause or a questionable guesswork?
Authors: Abstract Anti-Müllerian hormone (AMH) is a protein produced by pre-antral and small antral ovarian follicles. It is an acknowledged marker of ovarian reserve and remaining reproductive capacity, commonly used in reproductive medicine. From the third decade of life, AMH serum levels decrease consecutively up to menopause. Since the standardization of commercial assays, novel contributions of that parameter are being observed. Up to date, there is no screening tool for predicting the age of natural menopause (ANM). The following literature review evaluates the utility of AMH measurement in predicting A...
Source: Neuroendocrinology Letters - June 27, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Clear cell neuroendocrine tumor of the pancreas in von Hippel-Lindau disease: a case report and literature review.
Authors: Abstract Clear cell neuroendocrine tumor (NET) of the pancreas is found in von Hippel-Lindau (VHL) disease, multiple endocrine neoplasia type I (MEN I), and sporadic form. Clear cell NETs are often misdiagnosed as metastatic renal cell carcinoma. A 47-year-old woman with VHL was found to have a mass in the pancreatic tail and two masses in the right kidney with two cysts. A distal pancreatectomy and right radical nephrectomy were performed. The pancreatic lesion was a well-circumscribed, golden-yellow solid mass, which was lobulated by septal fibrosis. Microscopically, the tumor consisted of entirely of c...
Source: Neuroendocrinology Letters - June 27, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Multiple sclerosis in an acupuncture practice.
We present a case of 66-year-old female patient who has been treated by both conventional and Chinese traditional medicine after diagnosis was confirmed in 2008 as MS and antiphospholipid syndrome associated with CNS vasculitis. After diagnosis with clinical image confirmed with CT and MRI scan, where demyelinating zones were present, she started pharmacological therapy without major improvement. Patient suffered with fatigue, walking difficulties, weakness, was unable to articulate due to vocal cords spasms. We started acupuncture treatment in 2010 with herbal supplement therapy as well and patient had in total of 19...
Source: Neuroendocrinology Letters - June 27, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Intraoperative neurophysiological monitoring to protect the facial nerve during microsurgery for large vestibular schwannomas.
Authors: Abstract OBJECTIVE: Microsurgery is the preferred treatment for large vestibular schwannomas (VSs). However, anatomical and functional preservation of the facial nerve (FN) remains a challenge during this surgery. The aim of this study was to determine whether it is beneficial to the preservation rates of the FN during microsurgical treatment of large VSs using intraoperative neurophysiological monitoring (IONM). METHODS: We retrospectively reviewed 53 patients with large VSs that underwent microsurgical resection via the retrosigmoid approach in our department during April 2009 to March 2016. IONM wa...
Source: Neuroendocrinology Letters - June 27, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Psychometric evaluation of the Czech Beck Depression Inventory-II in a sample of depressed patients and healthy controls.
CONCLUSION: The Czech BDI-II shows adequate psychometric characteristics. PMID: 28650603 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - June 27, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Serum adiponectin levels in adolescents and young adults with growth hormone deficiency.
Authors: Abstract INTRODUCTION: Adiponectin (APN) is adipose tissue-derived hormone influencing energy metabolism. Growth hormone deficiency (GHD) may contribute to the development of disturbances in the hormonal function of adipose tissue (AT), and many disorders observed in untreated patients with GHD coincides with these contributed to low serum APN levels. OBJECTIVES: The assessment of serum adiponectin levels in adolescents and young adults with severe or partial GHD and analysis of relationships between serum APN and GH/IGF-1 axis function impairment as well as cardiometabolic risk factors. DESIGN AN...
Source: Neuroendocrinology Letters - June 27, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Angiotensin II enhancement during pregnancy influences the emotionality of rat offspring (Rattus norvegicus) in adulthood. Potential use of the Rat Grimace Scale.
CONCLUSION: We concluded that maternal activation of RAAS modified some aspect of emotionality of experimental animals and led to an enhanced emotional response to stress situation. PMID: 28650605 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - June 27, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Association of testosterone levels and heroin usage characteristics in male heroin users.
CONCLUSIONS: Our data reveal testosterone might promote injection drug use and repeated relapse in male heroin users. PMID: 28650606 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - June 27, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Endogenous glucocorticoids: role in the etiopathogenesis of Alzheimer's disease.
Authors: Abstract Endogenous glucocorticoids (eGCs) are steroid hormones with a wide spectrum of physiological effects. However, enhanced basal eGCs levels have been observed in patients affected by Alzheimer's disease (AD) and they have been correlated with dysregulation of the hypothalamic-pituitary-adrenocortical axis, hippocampal degeneration and reduced cognitive/memory performance. Therefore, it has been proposed that elevated concentration of eGCs might have a role in AD pathogenesis. AD is the most common form of dementia, characterized by the pathological accumulation of two proteins: the Amyloid Beta (A&...
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

A first case of adrenomyeloneuropathy with mutation Y174S of the adrenoleukodystrophy gene.
Authors: Abstract The patient first noticed spasticity and weakness in his legs. He was diagnosed with chronic myelogenous leukemia (CML); the symptoms were attributed to neuropathy associated with CML. By treatment with dasatinib, he achieved complete hematological remission, but his difficulty in walking was not improved. His neurological symptom worsened together with an increase in body temperature and then disappeared together with a normalized body temperature, which may be attributed to the Uhthoff's phenomenon often observed in multiple sclerosis. He later developed acute fever, vomiting and a high adrenoc...
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Effects of venlafaxine and chronic unpredictable stress on behavior and hippocampal neurogenesis of rat dams.
CONCLUSIONS: These results suggest that stress and antidepressant therapy can have significant impact on behavior and hippocampal neurogenesis in rat dams. PMID: 28456144 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Autophagy plays beneficial effect on diabetic encephalopathy in type 2 diabetes: studies in vivo and in vitro.
CONCLUSION: These results demonstrate that autophagy activation confers protection to neurons under aberrant metabolism and that autophagy dysfunction in the hypothalamus occurs in the chronic metabolic disorder such as T2DM. PMID: 28456145 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Comparative effects of a fixed Polypodium leucotomos/Pomegranate combination versus Polypodium leucotomos alone on skin biophysical parameters.
CONCLUSIONS: Our results suggest that a fixed Polypodium leucotomos/pomegranate combination provides a greater improvement of skin biophysical parameters compared to Polypodium leucotomos alone in adult Caucasians. Our findings may have implications for optimizing systemic skin photoprotection and beautification strategies. PMID: 28456146 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Tyrosine hydroxylase gene expression is facilitated by alcohol followed by the degradation of the protein by ubiquitin proteasome system.
CONCLUSION: Transient ethanol-treatment facilitates TH gene expression and its phosphorylation in a PKA- and MEK-dependent manner to elevate dopamine biosynthesis, whereas continuous exposure to ethanol abolishes its potent effects on the dopaminergic function to reduce dopamine content. This reduction seems to originate from the decrease of TH protein level by degradation of the protein. Our current data may contribute to the better understanding of alcohol tolerance associated with degradation of TH protein to reduce total-TH level and dopamine biosynthesis. PMID: 28456147 [PubMed - as supplied by publisher] (Source:...
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Impact of emotional disorders on semen quality in men treated for infertility.
Authors: Abstract OBJECTIVE: Semen quality depends on factors such as lifestyle, environment, and hormone secretion. OBJECTIVE: The purpose of the study was to assess the correlation between emotional disorders and the secretion of selected hormones, and to assess the impact of these disorders on semen quality. METHODS: The study covered 60 fertile and 112 subfertile males. The sperm was obtained by masturbation, and examined directly after liquidation according to the 2010 criteria of the World Health Organization. The research instruments used were: the Beck Depression Inventory (BDI), and the State-Trai...
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Plasma chemerin in young untrained men: association with cardio-metabolic traits and physical performance, and response to intensive interval training.
This study aimed to assess the association of chemerin with cardiometabolic risk and physical performance and examine its response to high-intensity interval training (HIIT). METHODS: Eighteen young men have been applied a HIIT program during 8 weeks. Plasma chemerin together with several cardiometabolic factors and physical performance indices were determined before and after the training program. Plasma chemerin and insulin were assessed using immunoenzymatic methods. The homeostasis model assessment (HOMA-IR) index was calculated as an estimate of insulin resistance. RESULTS: Basal plasma chemerin was positively...
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Structural and construct validity of the Czech version of the Pittsburgh Sleep Quality Index in chronic insomnia.
CONCLUSIONS: The results highlight the issue of structural variance of the PSQI and in chronic insomnia point to the important role of the PSQI components of daytime dysfunction and sleep disturbances in showing comorbid symptoms with daytime sleepiness and psychopathology. PMID: 28456150 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - May 1, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

A case of pituitary stalk interruption syndrome with intermittent seizures as the first presentation.
Authors: Abstract Pituitary stalk interruption syndrome (PSIS) is a congenital disease with isolated growth hormone deficiency (GHD) or multiple anterior pituitary hormone deficiencies (MPHD). The typical clinical manifestations of PSIS are growth retardation, hypoglycemia or delayed pubertal development. However, few reports showed cases of PSIS were diagnosed with acute epileptic seizures accompanied by hyponatremia. Here, we report an 18-year-old female presenting with episodes of intermittent seizures for 13 years. The electrolyte examination on many occasions has shown hyponatremia, even as low as 99.9 mmol/L...
Source: Neuroendocrinology Letters - March 25, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Successful pregnancy after Intralipid addition to sildenafil and enoxaparin in woman with history of recurrent pregnancy loss (RPL).
CONCLUSION: Combination therapy that includes Intralipid may generate successful IVF outcome, although this problem merits further study, especially regarding safety issues. PMID: 28326740 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 25, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

The impact of childhood adversities on anxiety and depressive disorders in adulthood.
CONCLUSION: Childhood adversities were found to increase vulnerability to the distress, depression, fear and anxiety later in the life. However, specific correlations between a given childhood adversity and a specific form of depression or anxiety disorder were either not found or weak. This is in line with the generally accepted view considering each of these factors a non-specific stressor increasing vulnerability to mood and affect disorders later in life. PMID: 28326741 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 25, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Comparative assessment of calcitonin stimulation test using calcium gluconate and pentagastrin and the usefulness of procalcitonin basic and post-stimulation concentrations in the diagnosis of patients after surgery for medullary thyroid cancer.
CONCLUSION: The results of the study suggest a similar diagnostic value of the tests with CaG compared to the PG as stimulants. In the present study we noticed a trend of basic and post-stimulation concentrations of PCT to increase in the tests with PG and CaG which correspond with the elevated concentrations of CT. PMID: 28326742 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 25, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Dopamine receptors modulate T lymphocytes via inhibition of cAMP-CREB signaling pathway.
CONCLUSIONS: D2-like receptors, principally dopamine D3 and D4 receptors, promote differentiation and function of T lymphocytes towards anti-inflammatory T cell subsets by a negative link to cAMP-CREB pathway. PMID: 28326743 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 25, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Nutritional parameters and carbohydrate and fat metabolism after prolonged salsolinol administration in rats fed normal or high-fat diets.
CONCLUSIONS: Salsolinol might influence the regulatory mechanisms of body weight and epididymal fat pad accumulation through neurohormonal pathways. PMID: 28326744 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 25, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Evaluation of the psychometric properties of the brief Internalized Stigma of Mental Illness Scale (ISMI-10).
Authors: Abstract OBJECTIVES: A significant number of psychiatric patients stigmatize themselves because of their mental struggles. Such self-stigmatization has an adverse impact on patients' well-being and effectiveness of the treatment of mental disorders. The goal of this study was to standardize the brief Internalized Stigma of Mental Illness Scale (ISMI-10), which could be used in studies targeting the self-stigma among the psychiatric patients. METHOD: 354 psychiatric patients participated in the study between the years 2012 and 2014. All individuals were undergoing treatment in the outpatient care or th...
Source: Neuroendocrinology Letters - March 25, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Histopathological evaluation of intrauterine polyps and scrapings of the uterine cavity in women with endometrial polyp described in ultrasound.
CONCLUSIONS: This study showed no higher incidence of precancerous lesions and cancers of the endometrium in women with endometrial polyp described in ultrasound, who reported abnormal bleeding. Ultrasound-based diagnosis of endometrial polyps should therefore be verified both in women who report abnormal bleeding, as well as in asymptomatic women. PMID: 28326746 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 25, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research