Limbic encephalitis associated with antibodies against the α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid receptor: a case report.
We report a case of a 51-year-old man with limbic encephalitis (LE) associated with antibodies against the α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid receptor (AMPAR). The patient presented with anterograde memory loss for 2 months. Cranial magnetic resonance and electroencephalogram were normal. AMPAR antibodies were found in blood serum and cerebrospinal fluid. All other test results were unremarkable. CT scans found a tumor in the right lobus superior pulmonis. A CT-guided needle biopsy was performed and pathological results showed small cell lung cancer (SCLC). The patient was diagnosed with LE associat...
Source: Neuroendocrinology Letters - September 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Diagnosis and treatment of solitary fibrous tumor/hemangiopericytoma of central nervous system. Retrospective report of 17 patients and literature review.
Authors: Ma L, Wang L, Fang X, Zhao CH, Sun L Abstract To investigate the diagnosis, treatment and prognosis of solitary fibrous tumor (SFT)/ hemangiopericytoma (HPC) of central nervous system (CNS), we retrospectively reviewed records of 17 patients who were treated for CNS SFT/HPC at the Department of Neurosurgery, China-Japan Union Hospital of Jilin University from December 2010 to June 2016, and reevaluated their pathological diagnoses according to the 2016 WHO classification of CNS tumors. We then analyzed their clinical symptoms, imaging characteristics, treatments and outcomes. Clinical manifestations of CNS...
Source: Neuroendocrinology Letters - September 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

The Comorbidity of Focal Epilepsy and Narcolepsy Type 1 - Two Case Reports.
Authors: Klobucnikova K, Siarnik P, Muchova I, Štofko J, Kollar B Abstract The aim of this study is to remind the possibility of co-occurrence of epilepsy and narcolepsy. In the first case report, narcolepsy type 1 was diagnosed in 29-year-old female. After one year of the treatment with modafinil a new episodes of automatic behavior appeared. Patient was reevaluated and the diagnosis of focal epilepsy with partial complex seizures was established. Patient was treated with modafinil and lamotrigine and became seizure-free. In the second case report a 21-year-old female was referred with a typical histor...
Source: Neuroendocrinology Letters - September 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Rapidly progressive non-alcoholic fatty liver disease due to hypopituitarism. Report of 5 cases.
CONCLUSION: Hypopituitarism may be a rare cause of rapidly progressive NAFLD. Insulin resistance and metabolic disorders caused by multiple hormonal deficiencies may contribute to it. Hormone supplement therapy, especially the growth hormone supplement, should be given at the early age to prevent the severe liver disease. PMID: 30183204 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - September 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Expression of MT1 receptor in patients with gastric adenocarcinoma and its relationship with clinicopathological features.
Authors: Sargazi F, Shokrzadeh M, Abediankenari S, Hoseini SV, Nasrabadi NN, Najafi M, Haghi-Aminjan H, Mirmajidi SH, Ataee R Abstract Gastric cancer accounts 8% of the total cancer cases leading to 10% of total cancer deaths worldwide. The indoleamine N-acetyl-5-methoxytryptamine, better known as melatonin, is the principal hormone produced by the pineal gland. Recently, it has been well documented some anti-cancer roles of melatonin in some malignancies as breast and colon cancer; as well as some its protective roles in the GI tract that have been known as free radical scavenger, antimitogenic and apoptotic prope...
Source: Neuroendocrinology Letters - September 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Integrated analysis of differentially expressed lncRNAs in Medial Temporal Lobe Epilepsy.
CONCLUSIONS: This study will be useful to explore the potential candidate biomarkers for diagnosis, prognosis, and drug targets of MTLE. PMID: 30183206 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - September 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Autonomic dysfunction in patients with irritable bowel syndrome evidenced by alterations of salivary alpha-amylase secretion.
CONCLUSION: This is the first attempt to associate sAA secretion with the pathophysiology of IBS. Our results suggest an autonomic dysfunction in IBS patients. PMID: 30183207 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - September 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Effects of alprostadil combined with calcium dobesilate in patients with diabetic peripheral neuropathy.
Authors: Han K, Liu C, Shi X, Rao X Abstract OBJECTIVE: To observe the clinical curative effects of alprostadil combined with calcium dobesilate in type 2 diabetes patients with peripheral neuropathy. METHODS: We randomly divided 120 type 2 diabetes patients with diabetic peripheral neuropathy into two groups. The treatment group was prescribed alprostadil (10 μg, once daily) and oral calcium dobesilate (0.5 g, 3 times daily), and the control group was prescribed alprostadil (10 μg, once daily) for a total treatment duration of 2 weeks. The Michigan Diabetic Neuropathy Score (MDNS) and the Michigan Neurop...
Source: Neuroendocrinology Letters - September 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Amygdala and emotionality in Parkinson's disease: An integrative review of the neuropsychological evidence.
Authors: Abstract Parkinson\'s disease (PD) is often accompanied by significant changes in emotionality, such as apathy, anhedonia, anxiety and depression. The present review summarizes the empirical evidence, including amygdala changes and psychological changes in emotionality in people suffering with PD. Seventeen empirical full-text articles including research on both amygdala and emotionality in PD were reviewed.The changes in amygdala volumes as well as changes in binding potentials, functional connectivity, regional homogeneity and regional cerebral blood flow were found to have various impacts on emotionali...
Source: Neuroendocrinology Letters - June 20, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Discrepancy between readiness to change, insight and motivation in alcohol-dependent inpatients.
CONCLUSIONS: The intention and motivation to alcohol dependence treatment seem to be high at the beginning of the treatment, but recognition of the alcohol problems were low in highly dependent patients. Marital status was connected with an increased active component for readiness to change. The passive component (decreasing the ambivalence) was observed in the unmarried patients. PMID: 29919989 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - June 20, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Physiological responses to different neuromuscular movement task during eccentric bench press.
Authors: Wilk M, Stastny P, Golas A, Nawrocka M, Jelen K, Zajac A, Tufano JJ Abstract OBJECTIVES: Increasing muscular hypertrophy is one of the main reasons for participating in a resistance training program, where different movement task such as eccentric cadences may serve as a potent hypertrophic stimulus and improve movement stability. Aim of this study was to investigate the physiological responses between slow 6/0/2/0 (SLOW) and moderate 2/0/2/0 (REG) eccentric cadences during five sets of bench press to failure using 70% 1 repetition maximum (1RM). MATERIALS AND METHODS: Blood samples from sixteen men (2...
Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Signs of impaired blood-brain barrier function and lower IgG synthesis within the central nervous system in patients with schizophrenia or related psychosis, compared to that in controls.
CONCLUSIONS: In this study we show that patients with schizophrenia or related psychosis have impaired BBB function and lower IgG synthesis within the CNS, compared to controls. These findings support the view that a pathological process within the CNS, combined with an aberrant immune system, may underlie the development of schizophrenia. PMID: 29803205 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Lymphocytic hypophysitis associated with Behcet's disease: A case report and review of the literature.
Authors: Tao T, Zhang Z, Li H Abstract Lymphocytic hypophysitis (LH) is a rare inflammatory disorder involving the pituitary gland, often with other autoimmune diseases combined. The coexistence of LH and Behçet\'s disease (BD) is a rare combination and only one case was reported in the previous literatures. A 50-year-old man was admitted into Sir Run Run Shaw Hospital presented with frontal headache and fatigue which had lasted for four months. Endocrinological inspection indicated anterior pituitary dysfunction. Magnetic resonance imaging (MRI) revealed homogeneous pituitary enlargement and thickened pitui...
Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Telomere length and TERT abnormalities in pituitary adenomas.
CONCLUSION: The results indicate that telomerase abnormalities do not play a role in pathogenesis of pituitary tumors. PMID: 29803207 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Content of fatty acids in a diet and the homocysteine levels in women with fertility disorders.
Authors: Czerwonogrodzka-Senczyna A, Jerzak M, Jeznach-Steinhagen A, Karzel K, Boniecka I Abstract OBJECTIVES: Assessment of the effects of consumption of fatty acids on the homocysteine levels in women with fertility disorders. METHODS AND RESULTS: The study included 286 women at the age between 23 and 46 years (the mean 33.13±4.21 years) with a fertility disorders. We measured: levels of homocysteine [μmol/L] (n=171), body weight and height (n=286). Body mass index (BMI) was calculated. A diet was assessed by 3-day dietary food records method including one day of the weekend. The mean homocysteine (...
Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Antipsychotics in Hyperthyroid-Related Psychosis: Case Report and Systematic Review.
CONCLUSION: Choice of antipsychotic in hyperthyroid-related psychosis should be primarily based on side-effect profile and medical comorbidities. Risperidone is the optimal and seemingly effective choice for treating hyperthyroid-related psychosis in an elderly thyrotoxic patient. PMID: 29803209 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Oncocytic thyroid carcinoma and multiple sclerosis: Fortuitous or drug-related association?
Authors: Handra-Luca A, Bacci F Abstract Sir, Thyroid tumors occur rarely as associated to nervous system diseases. We had recently studied a case of thyroid carcinoma, peculiar by the predominant eosinophilic/oncocytic/oxyphil/Hurthle cell-component associated to multiple sclerosis (MS). The patient (man, 31-years old) presented with hair loss, diarrhea, thermophobia, tremor and tachycardia. The medical history revealed allergy (pollen, prawn), recurrent uveitis and optic nevritis (at the age of 12-years). A Behcet disease was suspected. Corticoid treatment was given for more than 6 years. Actually, a right iso- a...
Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Estimation of testosterone/cortisol ratio by resting state eeg delta/beta ratio in elderly people.
CONCLUSION: Resting state EEG is a non-invasive approach that can be used to estimate hormone levels, which are possible biomarkers of physiological and psychological disorders. PMID: 29803211 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - May 30, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

An open prospective pilot study of a herbal combination "Relief" as a supportive dietetic measure during alcohol withdrawal.
An open prospective pilot study of a herbal combination "Relief" as a supportive dietetic measure during alcohol withdrawal. Neuro Endocrinol Lett. 2018 Mar 01;39(1):1-8 Authors: Mansoor K, Qadan F, Hinum A, Schneider C, Hechenbichler K, Schmidt M, Linsinger G, Matalka K Abstract OBJECTIVE: A herbal combination (saffron extract, passion flower herb extract, cocoa seed extract, radish extract and black cumin extract) called "Relief" was designed as a supportive therapy of alcohol withdrawal syndrome (AWS). This combination was based on the scientific evidence of each constituent effe...
Source: Neuroendocrinology Letters - April 3, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Positive and negative symptoms in schizophrenia and their relation to depression, anxiety, hope, self-stigma and personality traits - a cross-sectional study.
Authors: Vrbova K, Prasko J, Holubova M, Slepecky M, Ociskova M Abstract OBJECTIVE: The purpose of the investigation was to explore the relationship between positive or negative symptoms, social anxiety, hope, personality, and self-stigma in patients with schizophrenia spectrum disorders. METHOD: 57 outpatients took part in this cross-sectional study. The structured interview M.I.N.I. International Neuropsychiatric Interview was used to confirm the diagnosis. All patients completed the Liebowitz Social Anxiety Scale, Internalized Stigma of Mental Illness Scale, Beck Depression Inventory-II, Beck Anxiety Invento...
Source: Neuroendocrinology Letters - April 3, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Supplementation of Caricol ®-Gastro reduces chronic gastritis disease associated pain.
DISCUSSION: Due to the inherent biological activities of ingredients of papaya and of oats and their known effects (anti-inflammatory, epithelial integrity), the observed beneficial effects may be owed to the constituents synergisms to reduce chronic inflammation. We conclude, that the regular intake is a safe add on therapeutic option for patients with chronic gastritis to support standard medical care. PMID: 29604620 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - April 3, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

The role of lifestyle changes in the treatment of polycystic ovary syndrome.
Authors: Smyka M, Grzechocinska B, Wielgos M Abstract Polycystic ovary syndrome is one of the most common endocrinopathy of the reproductive age. Heterogenity of its clinical symptoms is related to the presence of a number of phenotypes of this disfunction, hence the necessity for individualized treatment is needed. A change of a lifestyle, well-balanced diet and physical activity are the most effective medical way contributing to the improvement of carbohydrate metabolism parameters and weight reduction which reactivates regular ovulation and facilitates getting pregnant. A change of diet should encompass determin...
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Possible etiology and treatment of amyotrophic lateral sclerosis.
Authors: Holecek V, Rokyta R Abstract Amyotrophic Lateral Sclerosis (ALS) is one of the most dangerous and least understood diseases with a pathophysiology that is still largely unknown. In this article we try to provide a pathophysiological explanation of the etiological, pathogenetic, and clinical aspects of ALS. After a description of the rather complicated classification of the disease, we continue with an evaluation of its clinical presentation. The bibliography reveals several suspect etiological factors including atherosclerosis, inflammation, tumors, cataracts, diabetes mellitus type 2, aging, and degenerat...
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

A pituitary abscess with one year follow-up after conservative treatment: A case report.
We reported a case of a 58-year-old woman with a history of type 2 diabetes (T2DM) exhibited with headaches, nasal discharge, anosmia, diabetes insipidus and hypopituitarism due to PA, she was diagnosed based on clinical presentations, endocrine examination and MRI image features. She was treated with nasal wash and antibiotic therapy without surgical intervention. She has received hormone replacement therapy for one year and her condition has gradually become stabilized. Meanwhile, the lesion of MRI image didn't become serious after one year. Conservative treatment might be an option for the patients with PA, those reject...
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Expression of matrix metalloproteinase enzymes in endometrium of women with abnormal uterine bleeding.
Authors: Grzechocinska B, Dabrowski FA, Chlebus M, Gondek A, Czarzasta K, Michalowski L, Cudnoch-Jedrzejewska A, Wielgos M Abstract OBJECTIVES: Abnormal uterine bleeding (AUB) is caused by derangement of physiological processes of tissue growth, shedding and regeneration. It is known that interplay between metalloproteinases (MMP's) and tissue inhibitors of metalloproteinases (TIMP's) may play a crucial role in its occurrence. AIM: To define if expression of proMMP-2, MMP-2 and TIMP-1 in endometrium of women with AUB is dependent on steroid sex hormone concentration and histopathological picture. MATERIALS ...
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Effect of the DASH-diet and salt Kardisal ® on blood pressure in adolescents with prehypertension (Cooperative multicentre interventional study).
Effect of the DASH-diet and salt Kardisal® on blood pressure in adolescents with prehypertension (Cooperative multicentre interventional study). Neuro Endocrinol Lett. 2018 Feb 06;38(8):544-548 Authors: Janda J, Veleminsky M, Sulakova T, Prochazka B, Eliasek J, Stransky P, Rokyta R Abstract BACKGROUND: In a cooperative multi-center interventional study of 60 probands with prehypertension and normal BMIs were followed for 3 months. DESIGN: The intervention included the DASH diet for 3 months in 30 probands plus sodium limited intake using the low sodium salt Kardisal® (60% NaCl, 40% KCl) (gr...
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

QTc prolongation after ADHD medication.
CONCLUSION: This is the first study revealing QTc prolongation in the group of ADHD children from the same region after 8-week treatment with atomoxetine and methylphenidate, indicating the potential discrete abnormalities in cardiac functioning associated with polymorphisms in genes of dopaminergic and noradrenergic system. PMID: 29504733 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Estimation of vitamin D status in patients with secondary and primary hypothyroidism of different etiology.
CONCLUSIONS: These findings confirm the necessity for vitamin D status improvement in the general population and more effective healthcare of hypothyroid patients. PMID: 29504734 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Does autoimmunity play a role in the risk of implantation failures?
The objective of this study was to investigate different autoantibodies peripheral blood profile after excluding anatomical, endocrinological, endometrial and genetic disorders and to estimate the risk of implantation failures. The study's including criteria were 1.indications for IVF/ET determined by male factor and unexplained infertility 2. absence of implantation after two consecutive cycles of IVF, ICSI or frozen embryo replacement cycles. The presence of ANA in the sera increased the risk of RIF after ET/IVF procedures, especially in older patients. Patients with RIF have a higher frequency of the presence of autoant...
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Anxiolytic effects of venlafaxine/olanzapine combination in treatment of anxious depression.
CONCLUSION: Our results indicate that VOC could replace another anxiolytic medication in managing the symptoms of anxiety in patients with severe anxious MDD already within the first week of treatment. PMID: 29504736 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Anxiety disorders and marital satisfaction.
CONCLUSION: Distress elements that contribute to the development of anxiety disorders can be diverse and sometimes it is not easy to identify so-called precipitating factors. The link between anxiety disorders and family relationships is bi-directional: psychological problems adversely affect patient relationships and attitudes of the partner towards the patient significantly affect his/her anxiety. PMID: 29504737 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - March 7, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Insight in schizophrenia - a double-edged sword?
Authors: Abstract Lack of insight is defined as a loss of ability to distinguish that one's unusual and unreal experiences should be the symptoms of the psychiatric disorder requiring treatment. Lack of insight may be considered as a core symptom of schizophrenia. The concept of insight has been regarded for a long time as necessary for treatment, which improves adherence and makes a better prognosis. Increased insight in schizophrenia has been associated not only with benefits, but also bring trouble in the form of self-stigma, low self-esteem, reduced patient's hope, diminished quality of life, and increased sui...
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Melatonin with adenosine solubilized in water and stabilized with glycine for oncological treatment - technical preparation, effectivity and clinical findings.
Authors: Abstract Melatonin has shown the potential to inhibit growth of different tumors, both in vitro and in vivo. There is clear evidence that the administration of melatonin alone or in combination with chemo and radiotherapy in cancer patients with advanced solid tumors has been associated with improved outcomes of tumor regression and survival. Moreover, chemotherapy has been shown to be better tolerated in patients treated with melatonin. However, there are different ways of preparation and administration of melatonin to the patient. This review article aims to offer the insight into the preparation, biolo...
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

How long does the pharmacokinetic interaction between carbamazepine and quetiapine last after carbamazepine withdrawal?
CONCLUSION: We hypothesize that induction of CYP3A lasts even after carbamazepine withdrawal. Our hypothesis was confirmed during the next treatment of mania. The patient had been off carbamazepine for 1 year and her serum level was four times higher (210 ng/ml) on 600 mg of quetiapine than 3 weeks after carbamazepine withdrawal. The influence of carbamazepine on CYP3A enzymes lasted at least 3 weeks after carbamazepine withdrawal which is in accordance with CYP3A de-induction lasting 3 weeks. This could be important information for psychiatrists to know that in some patients it is better to use a minimum washout period of...
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

A case of hereditary thrombophilia in a Chinese Han patient with both antithrombin deficiency and Factor V Leiden: A case report and literature review.
We report the case of a 22-year-old female who experienced recurrent intracranial venous thromboses, furthermore, color Doppler ultrasound showed multiple extracranial thromboses. Thrombophilia was suspected and screening tests indicated decreased AT activity and activated protein C sensitivity ratio, then further sequencing analysis identified missense mutations in SERPINC1 and F5. The patient's condition slightly improved after treatment with low molecular heparin during hospitalization followed by oral warfarin after discharge. The present report highlights a very rare case of thrombophilia with concurrent occurrence of...
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Application of physiotherapy in persons at risk of metabolic syndrome development.
Authors: Abstract Problems the locomotor activity and nutritional provisions in the treatment of obesity or metabolic syndrome are currently widely discussed. Based on prevailing experience, the attention in the field of locomotor and fitness activities is rather general, i.e. is mainly focused on the development of the general body fitness and reduction fitness programmes. However, no long-term effects of the locomotor therapy can be expected without appropriate and particularly targeted physiotherapy with a thorough kinesiological examination. Case report described here monitored the course of a three-month phys...
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Postoperative hypoparathyroidism in patients after total thyroidectomy - retrospective analysis.
CONCLUSIONS: Serum PTH levels below 5 pg/ml seems to be a good prognostic factor of the occurrence of hypocalcaemia symptoms. The information about low PTH concentration allows to start the pharmacotherapy faster and avoid clinical manifestation of hypocalcaemia. PMID: 29369600 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Study of locomotion, rearing and grooming activity after single and/or concomitant lesions of central and peripheral nervous system in rats.
CONCLUSION: Results of our study confirmed the physiological and pathophysiological differences in the movement stereotype between locomotion, rearing and grooming caused by the characteristics and algorithms of the movements, which are inborn to rats - the dominant role of the forelimbs in locomotion, the dominant exploratory activity in rearing, and the precise syntactic movement pattern in grooming. PMID: 29369601 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Evaluation of the amoxicillin concentrations in amniotic fluid, placenta, umbilical cord blood and maternal serum two hours after oral administration.
The objective of this study was to assess amoxicillin concentrations in amniotic fluid, umbilical blood, placenta and maternal serum two hours following oral administration among pregnant women at term and to assess obstetric and non-obstetric factors that might affect amoxicillin's penetration of these tissues. MATERIALS AND METHODS: A total of 30 full-term pregnant women who qualified for elective Caesarean delivery were included in the study. Amoxicillin at a dose of 500 mg was administered prior to surgery. Amoxicillin levels were determined by diffusion microbial assay. RESULTS: The maternal serum, placental, ...
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Circadian blood pressure profiles and ambulatory arterial stiffness index in children and adolescents with congenital adrenal hyperplasia due to 21-hydroxylase deficiency in relation to their genotypes.
The objective of the study was to evaluate vascular abnormalities in 21-OHD children and adolescents in relation to their genotypes. DESIGN: A cross-sectional study conducted at a tertiary referral center. PATIENTS: Seventy patients with 21-OHD CAH (27 boys), aged from 3 to 17.9 years: 9 with nonclassic CAH, 61 with classic CAH: 10 with simple virilising (SV) and 51 with salt wasting CAH (13-Del/Del, 8-Del/I2G, 7-I2G/I2G and 23-other genotypes). MAIN OUTCOMES MEASURES: The assessment of systolic and diastolic BP (SBP, DBP) loads, night dip% and arterial ambulatory stiffness index (AASI) in 21-OHD CAH patients. ...
Source: Neuroendocrinology Letters - January 27, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

The impact of air pollution to central nervous system in children and adults.
Authors: Sram RJ, Veleminsky M, Veleminsky M, Stejskalová J Abstract The aim of this paper was to review studies analyzing the associations between air pollution and neurodevelopment in children as well as the effect on adult population. Effect of prenatal exposure to polycyclic aromatic hydrocarbons (PAHs, benzo[a]pyrene, B[a]P) were already studied on cohorts from New York, Poland, China, and Spain. All results indicate changes of child behavior and neurodevelopment at the age of 3-9 years, decrease of IQ, increase of Attention Deficit Hyperactivity Disorder (ADHD), decrease of brain-derived neurotrophic f...
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Severe chronic lithium intoxication in patient treated for bipolar disorder.
CONCLUSION: Lithium is still very effective drug, but requires regular monitoring of serum levels to prevent overdose and symptoms of intoxication. Neurophysiological methods, including EEG and EMG, are strongly recommended to determine the level of peripheral and/or central nervous system impairment. PMID: 29298279 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Complete objective response, stable for 5 years, with the Di Bella Method, of multiple-metastatic carcinoma of the breast.
We present a case of a woman with carcinoma of the breast and multiple metastases after right mastectomy, axillary dissection, repeated cycles of chemo and radiotherapy, and estrogen block. Biological method formulated by Prof. L. Di Bella (DBM) produced a complete and stable objective response without toxicity. The DBM includes antiproliferative molecules, such as somatostatin, prolactin and estrogen inhibitors together with differentiating and apoptotic molecules such as melatonin (MLT), Retinoids, Vitamin E, D3, Vit. C, Calcium, Amino sugars, associated with metronomic microdoses of chemotherapy drugs. The blood tests d...
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

An experimental model of the "dual diagnosis": Effect of cytotoxic brain edema plus peripheral neuropathy on the spontaneous locomotor activity of rats.
CONCLUSION: The presented results show that the LA of rats with combined lesions is significantly lower compared to the activity of rats with a single lesion in the CNS or PNS. Results also indicate that the already induced endoneurial edema prevents subsequent accumulation of water applied to the intimate vicinity of the peripheral nervous structures. PMID: 29298281 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

The effects of growth hormone therapy on the somatic development of a group of Polish children with Silver-Russell syndrome.
CONCLUSIONS: Growth hormone therapy accelerates the growth of children with SRS but to a smaller extent than the growth of children born with intrauterine growth retardation without dysmorphic features. PMID: 29298282 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Kisspeptin permits the sexual development of female rats with normal and precocious puberty but is not a trigger for it.
CONCLUSION: the hypothalamic KISS-1/GPR54 system might permit the onset of puberty, but is not its primary trigger. Hormone levels were lower and gonadal maturity markers in the CPP groups were worse than in the control groups. PMID: 29298283 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Adherence, self-stigma and discontinuation of pharmacotherapy in patients with anxiety disorders - cross-sectional study.
CONCLUSIONS: Self-stigma significantly affects the current adherence to the treatment of neurotic spectrum disorders. PMID: 29298284 [PubMed - as supplied by publisher] (Source: Neuroendocrinology Letters)
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

The relationship between breast cancer treatment, tumour type and vitamin D level in pre- and postmenopausal women.
Authors: Streb J, Glanowska I, Streb A, Szpor J, Kryka K, Potocki P, Wójcik M, Jach R Abstract OBJECTIVE: Vitamin D deficiency has been linked to a higher risk of cancer. There is insufficient data regarding the influence of treatment on vitamin D status. The aim of this study was to compare pre- and post-treatment levels of 25(OH)D in premenopausal and postmenopausal women with breast cancer with a different receptor status (ER-estrogen receptors, PR-progesterone receptors) and in healthy controls. METHODS: 49 patients with breast cancer (23 premenopausal), and 28 healthy controls matched for age, menop...
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

New criteria for gestational diabetes mellitus - do they impact the outcome?
Authors: Zareba-Szczudlik J, Pykalo-Gawinska D, Gawinski C, Lewandowski Z, Malinowska-Polubiec A, Dobrowolska-Redo A, Czajkowski K, Wilczynski J, Romejko-Wolniewicz E Abstract OBJECTIVE: The aim of the study was to compare the perinatal outcome of pregnancies in mothers who were diagnosed with gestational diabetes mellitus (GDM) with previous versus current Polish Gynecological Society (PTG) criteria. METHODS: 475 patients were divided into three groups. In group A, the patients only met the previous PTG criteria for a GDM diagnosis, i.e., those with a blood glucose level of 140-152 mg/dl 2 hours after a...
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Polysomnography-based diagnosis in Mexican adult patients with Obstructive Sleep Apnea Syndrome (OSAS) clinical suspicion.
In this study, 51 subjects from 24 to 77 years old (54.1±12.12) were included in the study; 23 males and 28 females; 78.43% were overweight or obese; 35.29% were smokers; 31.37% alcohol consumers; 47.05% hypertensive; 21% diabetics; 35.29% with airway alterations; 29.41% with depression; 13.72% dyslipidaemic and 7.84% with ischemic heart disease. Only 22 of the subjects qualified for OSA and the concordance between the clinical diagnostic and polysomnographic recording was 54% (Ko=0.60, Ke 0.50, Ka=0.20) with a 0.55 sensibility, 0.66 specificity, PPV 0.54, NPV 0.65, PLR 1.2, RVN 0.69 and PPP 0.47. The neck circumfer...
Source: Neuroendocrinology Letters - January 4, 2018 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research