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Specialty: Endocrinology
Condition: Diabetes

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Total 1416 results found since Jan 2013.

Predicting Clinical Outcomes and Response to Thrombolysis in Acute Stroke Patients With Diabetes.
CONCLUSIONSStroke patients with diabetes have poorer outcomes compared with patients without diabetes, which is not explained by ICH. The iScore similarly predicts response to tPA between stroke patients with and without diabetes. PMID: 23359359 [PubMed - as supplied by publisher]
Source: Diabetes Care - January 28, 2013 Category: Endocrinology Authors: Nikneshan D, Raptis R, Pongmoragot J, Zhou L, Johnston SC, Saposnik G, on behalf of the Investigators of the Registry of the Canadian Stroke Network (RCSN) and the Stroke Outcomes Research Canada (SORCan) Working Group Tags: Diabetes Care Source Type: research

Association of glomerular filtration rate with outcomes of acute stroke in type 2 diabetic patients: results from the China National Stroke Registry.
CONCLUSIONSLow and high eGFRs (<45 ml/min/1.73m(2) or ≥120 ml/min/1.73m(2), respectively) are independent predictors of all-cause mortality and other poor outcomes after acute stroke in patients with type 2 diabetes. PMID: 24009297 [PubMed - as supplied by publisher]
Source: Diabetes Care - September 5, 2013 Category: Endocrinology Authors: Luo Y, Wang X, Wang Y, Wang C, Wang H, Wang D, Liu L, Jia Q, Liu G, Zhao X, Wang Y, on behalf of the CNSR investigators Tags: Diabetes Care Source Type: research

HbA1c measurement and relationship to incident stroke
ConclusionsThe frequency of diabetes testing was higher in patients who had experienced a stroke before and after their incident stroke compared with control patients but did not increase after their stroke. Glucose control improved significantly in the year after a stroke.This article is protected by copyright. All rights reserved.
Source: Diabetic Medicine - December 19, 2015 Category: Endocrinology Authors: R. Robson, A. Lacey, S. Luzio, H Van Woerden, M. Heaven, M. Wani, J. Halcox, L. Castilla‐Guerra, J. Dawson, J. Hewitt Tags: Short Report Source Type: research

Stroke Risk among Patients with Type 2 Diabetes Mellitus in Zhejiang: A Population-Based Prospective Study in China.
Conclusions. The relationship between stroke and T2DM was strong, especially in female. The incidence of stroke and stroke subtypes among patients with T2DM was up to 3-fold higher than in general population in Zhejiang province, especially the subtype of cerebral infarctions. PMID: 27403161 [PubMed]
Source: International Journal of Endocrinology - July 13, 2016 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Impact of glucose-lowering therapies on risk of stroke in type 2 diabetes.
Abstract Patients with type 2 diabetes (T2D) have an increased risk of stroke compared with people without diabetes. However, the effects of glucose-lowering drugs on risk of ischaemic stroke in T2D have been less extensively investigated than in coronary heart disease. Some evidence, including the UKPDS, has suggested a reduced risk of stroke with metformin, although the number of studies is limited. Inhibition of the KATP channels increases ischaemic brain lesions in animals. This is in agreement with a recent meta-analysis showing an increased risk of stroke with sulphonylureas vs. various comparators as both m...
Source: Diabetes and Metabolism - May 15, 2017 Category: Endocrinology Authors: Bonnet F, Scheen AJ Tags: Diabetes Metab Source Type: research

Prevalence of diabetes and its effects on stroke  outcomes: A meta‐analysis and literature review
ConclusionsApproximately one ‐third of all stroke patients have diabetes. Uniform methods to screen for diabetes after stroke are required to identify individuals with diabetes to design interventions aimed at reducing poor outcomes in this high‐risk population.
Source: Journal of Diabetes Investigation - October 13, 2018 Category: Endocrinology Authors: Lik ‐Hui Lau, Jeremy Lew, Karen Borschmann, Vincent Thijs, Elif I Ekinci Tags: Original Article Source Type: research

Elevated visceral adiposity index is associated with increased stroke prevalence and earlier age at first stroke onset: Based on a national cross-sectional study
ConclusionAlthough a causal relationship cannot be proven, higher VAI was positively associated with stroke prevalence and can lead to earlier stroke onset.
Source: Frontiers in Endocrinology - January 16, 2023 Category: Endocrinology Source Type: research

The impact of parental risk factors on the risk of stroke in type 1 diabetes
ConclusionA history of maternal stroke increases the risk of hemorrhagic stroke in individuals with type 1 diabetes. Other parental risk factors seem to have limited impact on the risk of stroke.
Source: Acta Diabetologica - March 15, 2021 Category: Endocrinology Source Type: research

Effect of diabetes on hospitalization for ischemic stroke and related in‐hospital mortality: a study in Tuscany, Italy, over years 2004–2011
ConclusionsIn the last decade, the incidence of ischemic stroke and of related in‐hospital mortality declined in persons without diabetes, while increasing among diabetic patients of advanced age. Women with diabetes, compared with men, had a higher in‐hospital mortality risk. Copyright © 2014 John Wiley & Sons, Ltd.
Source: Diabetes/Metabolism Research and Reviews - November 18, 2014 Category: Endocrinology Authors: Laura Policardo, Giuseppe Seghieri, Roberto Anichini, Alessandra De Bellis, Flavia Franconi, Paolo Francesconi, Stefano Del Prato, Edoardo Mannucci Tags: Research Article Source Type: research

Carotid intima-media thickness in plaque-free area, carotid plaque and risk of ischemic stroke in high-risk population of North China.
CONCLUSION: Screening of carotid artery especially for carotid artery plaques should be taken into consideration among people with high risk of ischemic stroke. PMID: 28759189 [PubMed - as supplied by publisher]
Source: Neuroendocrinology Letters - August 2, 2017 Category: Endocrinology Tags: Neuro Endocrinol Lett Source Type: research

Blood Pressure and Stroke Risk among Diabetic Patients.
Conclusions:The current study suggests a U-shaped association between blood pressure and the risk of stroke. Aggressive BP control (<110/65 mmHg) and high blood pressure (≥160/100 mmHg) are associated with an increased risk of stroke among both African American and white patients with type 2 diabetes. PMID: 23714680 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - May 28, 2013 Category: Endocrinology Authors: Zhao W, Katzmarzyk PT, Horswell R, Wang Y, Johnson J, Cefalu WT, Ryan DH, Hu G Tags: J Clin Endocrinol Metab Source Type: research

Genetic variation at the IGF1 locus shows association to post-stroke outcome and to circulating IGF-I.
CONCLUSION: Variation in rs7136446 of the IGF1 gene associates with post-stroke outcome in relatively young IS patients. Also, rs7136446 associates with s-IGF-I in controls but not in IS, which indicates that IS perturbs a normal genetic impact on s-IGF-I levels. PMID: 24005314 [PubMed - as supplied by publisher]
Source: European Journal of Endocrinology - September 4, 2013 Category: Endocrinology Authors: Aberg ND, Olsson S, Aberg D, Jood K, Stanne TM, Nilsson M, Blomstrand C, Svensson J, Isgaard J, Jern C Tags: Eur J Endocrinol Source Type: research

Chromium supplementation improved post-stroke brain infarction and hyperglycemia.
In this study, we investigated whether post-stroke hyperglycemia involved chromium dynamic mobilization in a rat model of permanent focal cerebral ischemia and whether dietary supplement of chromium improved post-stroke injury and alterations. Stroke rats developed brain infarction, hyperglycemia, hyperinsulinemia, glucose intolerance, and insulin resistance. Post-stroke hyperglycemia was accompanied by elevated secretion of counter-regulatory hormones including glucagon, corticosterone, and norepinephrine, decreased insulin signaling in skeletal muscles, and increased hepatic gluconeogenesis. Correlation studies revealed ...
Source: Diabetes Metab - October 19, 2015 Category: Endocrinology Authors: Chen WY, Mao FC, Liu CH, Kuan YH, Lai NW, Wu CC, Chen CJ Tags: Metab Brain Dis Source Type: research

Hypertension and Diabetes Mellitus as a Predictive Risk Factors for Stroke
Conclusion after summarising all the studies mentioned in the paper, it can be established that hypertension and diabetes mellitus are a stroke risk factors and correlated in patients with atherosclerosis.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - March 19, 2018 Category: Endocrinology Source Type: research

The effect of dulaglutide on stroke: an exploratory analysis of the REWIND trial
Publication date: Available online 7 January 2020Source: The Lancet Diabetes & EndocrinologyAuthor(s): Hertzel C Gerstein, Robert Hart, Helen M Colhoun, Rafael Diaz, Mark Lakshmanan, Fady T Botros, Jeffrey Probstfield, Matthew C Riddle, Lars Rydén, Charles Messan Atisso, Leanne Dyal, Stephanie Hall, Alvaro Avezum, Jan Basile, Ignacio Conget, William C Cushman, Nicolae Hancu, Markolf Hanefeld, Petr Jansky, Matyas KeltaiSummaryBackgroundCardiovascular outcome trials have suggested that glucagon-like peptide 1 (GLP-1) receptor agonists might reduce strokes. We analysed the effect of dulaglutide on stroke within the researchi...
Source: The Lancet Diabetes and Endocrinology - January 9, 2020 Category: Endocrinology Source Type: research