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Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease
ConclusionVascular comorbidity is significantly associated with cognitive and gait impairment in patients with early PD, which may have prognostic and treatment implications. © 2016 International Parkinson and Movement Disorder Society
Source: Movement Disorders - June 20, 2016 Category: Neurology Authors: Naveed Malek, Michael A. Lawton, Diane M. A. Swallow, Katherine A. Grosset, Sarah L. Marrinan, Nin Bajaj, Roger A. Barker, David J. Burn, John Hardy, Huw R. Morris, Nigel M. Williams, Nicholas Wood, Yoav Ben‐Shlomo, Donald G. Grosset, Tags: Research Article Source Type: research

Air Pollution Emerges as a Top Killer Globally – Part 1
Dark pollution clouds over Cairo. Credit: Khaled Moussa Al-Omrani/IPS.By Martin KhorPENANG, Nov 11 2016 (IPS)New research is showing that air pollution is a powerful if silent killer, causing 6.5 million worldwide deaths as well as being the major cause of climate change.   Air pollution has emerged as a leading cause of deaths and serious ailments in the world.  Emissions that cause air pollution and are Greenhouse Gases are also the main factor causing climate change.Therefore, drastically reducing air pollution should now be treated as a top priority.The seriousness of this problem was highlighted by the heavy smog ...
Source: IPS Inter Press Service - Health - November 11, 2016 Category: Global & Universal Authors: Martin Khor Tags: Environment Headlines Health air pollution Indoor air quality World Health Organization Source Type: news

7 Foot Problems That Can Be Serious
If you want to know the state of your health, try looking down. “There’s no question it’s extremely important that people pay attention to their feet,” says Terry Philbin, D.O., spokesperson for the American Academy of Orthopedic Surgeons (AAOS) and a foot and ankle specialist at the Orthopedic Foot and Ankle Center in Westerville, Ohio. The condition of your feet can give you clues to a host of medical issues, such as diabetes, arthritis, and even heart disease. Read on to find out what to look for and what it may mean. 1. Pain “There’s no pain that should be ignored,” says Jane ...
Source: Healthy Living - The Huffington Post - November 12, 2016 Category: Consumer Health News Source Type: news

Effects of vascular comorbidity in parkinson's disease
Vascular disease and risk factors are common in Parkinson's disease (PD) and may influence phenotype. Statin therapy may thus be indicated. 1759 recently diagnosed PD cases from a multicentre prospective study underwent a Montreal Cognitive Assessment and the Unified PD Rating Scale part 3 (UPDRS 3). History of vascular events, risk factors and statin usage was recorded. QRISK2 quantified cardiovascular risk. Mean age was 67.5 (SD 9.3), disease duration 1.3 (SD 0.9) years, 65.2% male. 4.7% had prior stroke/TIA, 12.5% cardiac disease, 30.4% hypertension, 27.3% high cholesterol, 20.7% obesity, 7.2% diabetes and 4.6% smokers....
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Swallow, D. M. A., Malek, N., Grosset, K. A., Lawton, M. A., Bajaj, N. P., Barker, R. A., Ben-Shlomo, Y., Burn, D. J., Morris, H. R., Williams, N., Wood, N. W., Grosset, D. G., on behalf of the PRoBaND collaborators Tags: Drugs: CNS (not psychiatric), Parkinson's disease, Hypertension, Memory disorders (psychiatry) ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Hypertension Canada ’s 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults
Publication date: Available online 10 March 2017 Source:Canadian Journal of Cardiology Author(s): Alexander A. Leung, Stella S. Daskalopoulou, Kaberi Dasgupta, Kerry McBrien, Sonia Butalia, Kelly B. Zarnke, Kara Nerenberg, Kevin C. Harris, Meranda Nakhla, Lyne Cloutier, Mark Gelfer, Maxime Lamarre-Cliche, Alain Milot, Peter Bolli, Guy Tremblay, Donna McLean, Sheldon W. Tobe, Marcel Ruzicka, Kevin D. Burns, Michel Vallée, G. V. Ramesh Prasad, Steven E. Gryn, Ross D. Feldman, Peter Selby, Andrew Pipe CM, Ernesto L. Schiffrin, Philip A. McFarlane, Paul Oh, Robert A. Hegele, Milan Khara, Thomas W. Wilson, S. Brian Penner, El...
Source: Canadian Journal of Cardiology - March 9, 2017 Category: Cardiology Source Type: research

ACR Appropriateness Criteria ® Cerebrovascular Disease
Diseases of the cerebral vasculature represent a heterogeneous group of ischemic and hemorrhagic etiologies, which often manifest clinically as an acute neurologic deficit also known as stroke or less commonly with symptoms such as headache or seizures. Stroke is the fourth leading cause of death and is a leading cause of serious long-term disability in the United States. Eighty-seven percent of strokes are ischemic, 10% are due to intracerebral hemorrhage, and 3% are secondary to subarachnoid hemorrhage.
Source: Journal of the American College of Radiology : JACR - May 1, 2017 Category: Radiology Authors: Expert Panel on Neurologic Imaging:, Michael B. Salmela, Shabnam Mortazavi, Bharathi D. Jagadeesan, Daniel F. Broderick, Judah Burns, Tejaswini K. Deshmukh, H. Benjamin Harvey, Jenny Hoang, Christopher H. Hunt, Tabassum A. Kennedy, Alexander A. Khalessi, Tags: Appropriate use criteria Source Type: research

All That Glitters Is not Gold: Peals and Pitfalls in I-131 Scans for Differentiated Thyroid Cancer
Conclusion: We review thyroid gland physiology and describe a systemic overview of potential false positive and false negative lack of uptake of radioiodine in the whole body along with illustrations and cases. By understanding the physiology and characteristics of radioiodine uptake and correlating with anatomical imaging, biochemical data, and clinical findings, physicians can be more confident in establishing proper management for patients with DTC using radioiodine whole body scans. Research Support: N/A
Source: Journal of Nuclear Medicine - May 24, 2017 Category: Nuclear Medicine Authors: Lazaga, F., Sharma, S., Sharma, P., Williams, S. Tags: Educational Exhibits Posters Source Type: research

Qool Therapeutics raises $8m to support temp management device
Early stage med device developer Qool Therapeutics said today it raised $8 million in a Series A-1 round to support development and trials of its Qool device designed for targeted temperature management and exercise recovery. Joining the funding round was Zhongji Holdings and Join Medical Technology, Tampcap LLC, BrilliMedical International, BioPacific Investors, Western Technology Investment and FundRx, the Silicon Valley-based company said. Qool Therapeutics said that in addition to the funding, it has also received an award from the US Department of Defense’s Defense Innovation unit Experimental organization. The ...
Source: Mass Device - November 28, 2017 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Research & Development Respiratory qooltherapeutics Source Type: news

Behavioural and physiological responses to low- and high-intensity locomotion in Chinese shrimp Fenneropenaeus chinensis
AbstractWe explored stroke behaviour, energy sources, and their related metabolic enzymes during multi-intensity swimming and tail-flipping at low- and high-intensity modes in Chinese shrimpFenneropenaeus chinensis. In swimming, shrimp were encouraged to swim at velocities of 3, 6, 9  cm s−1 for 200  min (low-intensity), and at 12, 15, 18 cm s−1 until fatigue (high-intensity). In tail-flipping, shrimp were encouraged to tail-flip by tapping cephalothorax at frequencies of 0.020, 0.040, 0.063  Hz (one tap every 50, 25, 16 s) for 5 min (low-intensity), and at 0.083, 0,100, 0.125 Hz (one tap every 12, 10, 8 s) u...
Source: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology - November 23, 2018 Category: Physiology Source Type: research

ReWalk Robotics shares fall on Q4, 2018 sales miss
Shares in ReWalk Robotics (NSDQ:RWLK) fell today after the rehabilitation exoskeleton maker posted fourth quarter and full year 2018 earnings that beat loss-per-share expectations but missed wide on sales consensus from Wall Street analysts. The Yokneam, Israel-based company posted losses of approximately $5 million, or 10¢ per share, on sales of approximately $1.6 million for the three months ended December 31, seeing losses shrink 18.6% while sales grew 4.2% when compared with its fourth quarter during the previous year. Losses per share were just ahead of the 14¢ consensus on Wall Street, where analysts expected too ...
Source: Mass Device - February 8, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Featured MassDevice Earnings Roundup Wall Street Beat ReWalk Robotics Source Type: news

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Motor Abilities in Adolescents Born Preterm Are Associated With Microstructure of the Corpus Callosum
Conclusions: Impairments in motor abilities are present in preterm born adolescents without major neuromotor impairment and in the absence of focal brain injury. Altered microstructure of the corpus callosum microstructure appears a crucial factor, in particular for movement quality. Introduction Very preterm birth (birth <32 weeks of gestation) is associated with high risk of impaired neurodevelopment. Rates of severe neuromotor impairment, i.e., Cerebral Palsy (CP), are decreasing, in particular in those preterm children born with moderately low and very low birth weight (1). However, in a substantial propo...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Should This Patient Be Screened for Atrial Fibrillation?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2019 Dec 03;171(11):828-836 Authors: Burns RB, Zimetbaum P, Lubitz SA, Smetana GW Abstract Atrial fibrillation (AFib) is the most common type of cardiac arrhythmia, affecting 2.7 million to 6.1 million persons in the United States. Although some persons with AFib have no symptoms, others do. For those without symptoms, AFib may be detected by 12-lead electrocardiogram (ECG), single-lead monitors (such as ambulatory blood pressure monitors and pulse oximeters), or consumer devices (such as wearable monitors and smartphones). Pulse pa...
Source: Annals of Internal Medicine - December 2, 2019 Category: Internal Medicine Authors: Burns RB, Zimetbaum P, Lubitz SA, Smetana GW Tags: Ann Intern Med Source Type: research

Clustering of functioning and disability profile based on the WHO disability assessment schedule 2.0 - a nationwide databank study.
Conclusion: We converted WHO Disability Assessment Schedule 2.0. functioning domain scores into six-dimensioned radar chart, and demonstrate disability restrictions can be further categorized into clusters according to similarity of functioning impairment. Understanding of disease-related disabilities provides an important basis for designing rehabilitation programs and policies on social welfare and health that reflect the daily-living needs of people according to diagnosis.Implication for RehabilitationThe use of radar charts provided a direct visualization of the scope and severity of disabilities associated with specif...
Source: Disability and Rehabilitation - June 10, 2020 Category: Rehabilitation Authors: Chen CP, Chen YW, Chang KH, Huang SW, Wu CH, Escorpizo R, Stucki G, Liou TH Tags: Disabil Rehabil Source Type: research

IJERPH, Vol. 18, Pages 2173: Use of mHealth Technology for Patient-Reported Outcomes in Community-Dwelling Adults with Acquired Brain Injuries: A Scoping Review
le) Kew John Morris The purpose of our scoping review was to describe the current use of mHealth technology for long-term assessment of patient-reported outcomes in community-dwelling individuals with acquired brain injury (ABI). Following PRISMA guidelines, we conducted a scoping review of literature meeting these criteria: (1) civilians or military veterans, all ages; (2) self-reported or caregiver-reported outcomes assessed via mobile device in the community (not exclusively clinic/hospital); (3) published in English; (4) published in 2015–2019. We searched Ovid MEDLINE(R) &amp;lt; 1946 to 16 August 2019, ME...
Source: International Journal of Environmental Research and Public Health - February 23, 2021 Category: Environmental Health Authors: Shannon B. Juengst Lauren Terhorst Andrew Nabasny Tracey Wallace Jennifer A. Weaver Candice L. Osborne Suzanne Perea Burns Brittany Wright Pey-Shan Wen Chung-Lin (Novelle) Kew John Morris Tags: Review Source Type: research