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Molecules, Vol. 27, Pages 6804: Alzheimer & rsquo;s Disease as a Major Public Health Concern: Role of Dietary Saponins in Mitigating Neurodegenerative Disorders and Their Underlying Mechanisms
This study highlights various neuroprotective mechanisms of saponins including free radical scavenging, modulation of neuroprotective signaling pathways, activation of neurotrophic factors, modulation of neurotransmitters, inhibition of BACE1 enzyme and tau hyper-phosphorylation. The study concludes that saponins have considerable efficacy against various pathological targets of neurological disorders, especially AD, and might be an important source of leads against neurodegenerative disorders.
Source: Molecules - October 11, 2022 Category: Chemistry Authors: Abduljawad Elawad Elkhalifa Ahmed Hamdoon Salim Ashraf Ayaz Hassan Bungau Tags: Review Source Type: research
Stroke: Sugar-free pop may hike the risk by almost 50% - it 'worsens' with higher intake
Curiously, the risk association was not seen in drinkers of regular soda.
Source: Daily Express - Health - October 2, 2022 Category: Consumer Health News Source Type: news
Unusual case of stroke in childhood
You receive a prealert call from a paramedic team stating they are managing a 12-year-old girl with acute left-sided weakness. As you prepare for the patient’s arrival, you go through a list of potential differentials. Question 1 Which of the following is not part of the differential list? Haemorrhagic stroke. Hypoglycaemia. Bell’s palsy. Migraine. Todds’ paresis. Question 2 What is the recommended time to CT following this type of presentation to the emergency department? 15 min. 40 min. 60 min. 120 min. The time to CT is only applicable to adult patients. The family report intermittent frontal headaches...
Source: Archives of Disease in Childhood - Education and Practice - September 19, 2022 Category: Pediatrics Authors: Mawhinney, D. C., Mullen, S., Clarke, N. Tags: Epilogue Source Type: research
Stroke: The seemingly 'harmless' drink associated with a 31% higher risk of stroke
THE DRINK, which is popular among people trying to lose weight and cut down on sugar, was associated with a 31 percent higher risk of a clot-caused stroke.
Source: Daily Express - Health - September 15, 2022 Category: Consumer Health News Source Type: news
Influencing factors of stroke occurrence and recurrence in hypertensive patients: A prospective follow ‐up studies
ConclusionsFor people with high blood pressure, it is necessary to exercise properly, control body weight, avoid obesity, quit smoking, reduce alcohol consumption, and reasonably control blood pressure, blood sugar, and blood lipid.
Source: Brain and Behavior - September 13, 2022 Category: Neurology Authors: Yuelong Jin,
Minmin Jiang,
Na Pan,
Yan Chen,
Weiwei Chang,
Lijun Zhu,
Zhengmei Fang,
Shizao Fei,
Zixuan Zhou,
Siyun Zhou,
Lianping He,
Yingshui Yao Tags: ORIGINAL ARTICLE Source Type: research
Health Highlights: Sept. 9, 2022
Artificial sweeteners may harm the heart. Sugar substitutes are a popular way to try to keep slim, but French research suggests they may also increase your risk for a heart attack or stroke. Read more
CT lung cancer screening catches more tumors...
Source: Drugs.com - Daily MedNews - September 9, 2022 Category: General Medicine Source Type: news
Influence of Optimal Management of Hyperglycemia and Intensive Nursing on Blood Glucose Control Level and Complications in Patients with Postoperative Cerebral Hemorrhage
CONCLUSION: Optimal management of hyperglycemia and intensive nursing can effectively control the blood sugar level of patients after cerebral hemorrhage, reducing insulin dosage, and the occurrence of hypoglycemia, pulmonary infection, and rebleeding.PMID:36072767 | PMC:PMC9444437 | DOI:10.1155/2022/8553539
Source: Computational and Mathematical Methods in Medicine - September 8, 2022 Category: Statistics Authors: Dandan Sun Liang Sun Fang Su Source Type: research
Nigeria: A Beep in Time Could Save a Life
[Nigeria Health Watch] Enoh Richard's doctor is reducing the number of pills she takes daily to keep her blood sugar under a healthy level. Previously, she was on 2,000mg of a blood sugar-controlling drug, 10mg of another to reduce the risk of heart failure or stroke, five units of insulin and she checked her blood sugar every day. After signing up on an app and starting a tailored diet, exercise and care plan, she now checks her blood sugar every other day. "It has stayed within 4.5% to 4.7%," she says. A reading between 4% and
Source: AllAfrica News: Health and Medicine - September 6, 2022 Category: African Health Source Type: news
Interaction of High-Sugar Diet and History of Stroke with Risk of Cognitive Decline in Older Adults
CONCLUSIONS A high-sugar diet and history of stroke interacted synergically in association with cognitive decline in older adults, which might provide a reference for management of cognition in older adults.PMID:36059134 | DOI:10.12659/MSM.937572
Source: Medical Science Monitor - September 5, 2022 Category: Research Authors: Qian Xu Sicong Zhang Yanqing Gu Ping Wang Qian Zhang Chunlei Shan Source Type: research
Drinking Black Tea May Lower Mortality Risk, Study Suggests
While green tea has a long-standing reputation for health benefits, research has been much more mixed on black tea. One problem, says Maki Inoue-Choi, an epidemiologist at the National Cancer Institute, is that large observational studies on tea and mortality have focused on countries like Japan or China—places where green tea is more popular.
To fill this gap, Inoue-Choi and her colleagues analyzed data in the United Kingdom, where black tea drinking is common. After surveying about 500,000 people and following them for a median of 11 years, the results, published Aug. 29 in the journal Annals of Internal Medicine, ...
Source: TIME: Health - August 29, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized Diet & Nutrition healthscienceclimate Source Type: news
High Blood Pressure and Diabetes Are Linked. Here ’ s How to Reduce Your Risk for Both
High blood pressure—also known as hypertension—and Type 2 diabetes are two of the most common medical conditions in the U.S. Unfortunately, they often occur together. Some research has found that 85% of middle-aged or older adults who have Type 2 diabetes also have hypertension, and both conditions elevate a person’s risk for heart disease, stroke, and kidney disease.
These increased risks are significant, and in some cases grave. Researchers have found that people with Type 2 diabetes are up to four times more likely to develop cardiovascular disease than those who don’t have the conditio...
Source: TIME: Health - August 29, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized Disease freelance healthscienceclimate Source Type: news
Sugar sweetened beverages intake and risk of obesity and cardiometabolic diseases in longitudinal studies: A systematic review and meta-analysis with 1.5 million individuals
Sugar-sweetened beverages (SSB) are associated with adverse outcomes in adults and understanding the strength, consistency and biological gradient of the association between SSB consumption and health-related outcomes is important. We aimed to examine longitudinal associations between sugar-sweetened beverages (SSB) intake and obesity and cardiometabolic diseases (type 2 diabetes, coronary heart disease and stroke) in adults.
Source: Clinical Nutrition ESPEN - August 23, 2022 Category: Nutrition Authors: Leonardo Pozza Santos, Denise Petrucci Gigante, Felipe Mendes Delpino, Ana Paula Maciel, Renata Moraes Bielemann Tags: Meta-analysis Source Type: research
Hawthorn fruit acid consumption attenuates hyperlipidemia-associated oxidative damage in rats
CONCLUSION: HFA administration can provide health benefits by counteracting the effects of hyperlipidemia caused by an HFD in the body, and the underlying mechanism of this event is closely related to the activation of the Nrf2/HO-1 signaling pathway.PMID:35990322 | PMC:PMC9384962 | DOI:10.3389/fnut.2022.936229
Source: Atherosclerosis - August 22, 2022 Category: Cardiology Authors: Yicheng Feng Shan Gao Ting Zhu Guibo Sun Peisen Zhang Yichun Huang Shuang Qu Xiaomeng Du Dehua Mou Source Type: research
Epileptic seizures during Non-Ketotic Hyperglycemia (NKH) in French Guiana: A retrospective study
ConclusionSeizures in NKH are symptomatic of an acute brain lesion or vascular epilepsy more than 1 in 2 times. However, isolated NKH can cause seizures with a suggestive brain MRI.
Source: Frontiers in Endocrinology - August 18, 2022 Category: Endocrinology Source Type: research
Following nature ' s rules, researchers develop new methods for treating degenerative neurological disease
Following nature's rules, researchers develop new methods for treating degenerative neurological disease
The University of Arizona has licensed the new class of drugs designed to penetrate the blood-brain barrier to startup Teleport Pharmaceuticals.
Paul Tumarkin
Tuesday
Tech Launch Arizonateleport-web-crop.jpg
Robin Polt (right) coaches undergraduate student Hannah Kuo Feinberg as she works on a glycopeptide project in Polt ’s lab.
Paul Tumarkin/Tech Launch ArizonaHealthScience and TechnologyCollege of Medicine - TucsonCollege of ScienceDeterminationExpertsExplorationTech Launch Arizona
Media contact(s)Paul...
Source: The University of Arizona: Health - July 26, 2022 Category: Universities & Medical Training Authors: mittank Source Type: research
