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Molecules, Vol. 28, Pages 126: In Vitro Evaluation of & alpha;-amylase and & alpha;-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Pterocarpus erinaceus Poir
Molecules, Vol. 28, Pages 126: In Vitro Evaluation of α-amylase and α-glucosidase Inhibition of 2,3-Epoxyprocyanidin C1 and Other Constituents from Pterocarpus erinaceus Poir
Molecules doi: 10.3390/molecules28010126
Authors:
Romeo Toko Feunaing
Alfred Ngenge Tamfu
Abel Joel Yaya Gbaweng
Larissa Mekontso Magnibou
Fidele Ntchapda
Celine Henoumont
Sophie Laurent
Emmanuel Talla
Rodica Mihaela Dinica
Diabetes mellitus is a metabolic disorder which is one of the leading causes of mortality and morbidities in elderly humans. Chronic diabetes can lead to kidney failure, blindness, limb a...
Source: Molecules - December 23, 2022 Category: Chemistry Authors: Romeo Toko Feunaing Alfred Ngenge Tamfu Abel Joel Yaya Gbaweng Larissa Mekontso Magnibou Fidele Ntchapda Celine Henoumont Sophie Laurent Emmanuel Talla Rodica Mihaela Dinica Tags: Article Source Type: research
Cerebral vascular function following the acute consumption of caffeinated artificially- and sugar sweetened soft drinks in healthy adults
Discussion: Acute consumption of caffeinated SSB and ASB resulted in lower intracranial artery blood velocity and conductance but had a minimal effect on cerebral vascular function as only MCA CVRCO2 was altered with the ASB compared to water.
Source: Frontiers in Human Neuroscience - December 22, 2022 Category: Neuroscience Source Type: research
Stroke, Dietary Fish, Milk, and Sugar Consumption Correlates of Alzheimer's and Parkinson's Dementia
To investigate the potentially confounding factors in the relationship between daily sugar intake versus Alzheimer& Parkinson's related death rates, including milk, meat, fish and alcohol consumption; obesity, stroke, hypertension, cancer and diabetes rates; tobacco use; and gross domestic purchasing power parity in different countries.
Source: Archives of Physical Medicine and Rehabilitation - December 1, 2022 Category: Rehabilitation Authors: Kurt Gold, Jacob Galloway, Justin Schwartz, Jonathan Huefner, Elizabeth Call, Taoyuan Beninato, Gabriela Garaycochea, Ronald Bulbulian Tags: Research Poster 2184247 Source Type: research
Association of 24 h Blood Pressure on Functional Outcome in Patients with Acute Ischemic Stroke Post Intravenous Thrombolysis
Conclusion: An elevated mean SBP and greater SBP variability were predictive of poor functional outcomes, whereas a high SBP variability predicted sICH. Our study emphasizes the need for BP control and minimizing large fluctuations to achieve good poststroke outcomes.Cerebrovasc Dis
Source: Cerebrovascular Diseases - November 24, 2022 Category: Neurology Source Type: research
Primary Prevention of Ischemic Stroke
This article provides an overview on conventional modifiable risk factors for ischemic stroke and highlights the emerging risk factors and approaches for high-risk group identification and treatment. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Seminars in Neurology - November 17, 2022 Category: Neurology Authors: Sabayan, Behnam Tags: Review Article Source Type: research
Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4 ‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury
Mol Med Rep. 2023 Jan;27(1):9. doi: 10.3892/mmr.2022.12896. Epub 2022 Nov 11.ABSTRACT3,4‑Dihydroxybenzaldehyde (DBD), one of the active components of Gastrodia elata, has a cerebral protective effect and can effectively combat cerebral ischemia/reperfusion (I/R) injury in rats. However, the metabolite profiles and underlying mechanisms associated with DBD remain unclear. To explore the level of energy metabolism and pharmacological targets in brain tissue following DBD treatment of stroke. The right middle cerebral artery of the rats was occluded for 2 h and reperfused for 24 h to simulate brain I/R injury. Pharmacologic...
Source: Molecular Medicine Reports - November 11, 2022 Category: Molecular Biology Authors: Yuan Luo Pu Chen Liping Yang Xiaohua Duan Source Type: research
How People With Diabetes Can Lower Stroke Risk
After spending nearly two decades trying to manage her Type 2 diabetes, Agnes Czuchlewski landed in the emergency room in 2015, with news that she’d just experienced a heart attack. She also learned that she had metabolic syndrome, a cluster of conditions that includes diabetes but also brings higher risk of heart disease and stroke.
“Because I needed to lose quite a bit of weight when I was first diagnosed, I was focused on the number I saw on the scale, and then on my blood-sugar numbers,” recalls Czuchlewski, 68, who lives in New York City. “I didn’t realize other numbers came into play, li...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: Elizabeth Millard Tags: Uncategorized Disease healthscienceclimate Source Type: news
What to Know About Diabetes and the Risk of Silent Heart Attacks
At first it seemed like a routine call—something the paramedics had dealt with countless times before. A man in his mid-50s was having a heart attack, and his physician had called for emergency support. But when the paramedics arrived, the physician pulled them aside and told them something peculiar: the man had no cardiovascular symptoms whatsoever.
The man had come to his doctor’s office because he’d woken early the previous morning sweating and with a sharp pain in his left wrist. These symptoms had quickly subsided and he’d gone back to sleep. Later, after going about his day, he’d visited...
Source: TIME: Health - November 4, 2022 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthscienceclimate heart health Source Type: news
Hospital Closures Pose Challenges to Care
Empty beds in a hospital room.
When 10-bed Nye Regional Medical Center, in west-central Nevada, closed abruptly in 2015, it meant that the residents of the former gold-mining town of Tonopah would have to drive about two hours across a hundred miles of desert roads to get to the nearest hospital.
The hospital’s CEO, Wayne Allen, didn’t sugar-coat it.
“This is a decision that will ultimately jeopardize the health and well-being of our community and surrounding areas,” he said.
Hospital closures over the last decade—most notably in rural areas and in pediatrics, but urban closures as well—have left patients wi...
Source: The Hospitalist - November 1, 2022 Category: Hospital Management Authors: Ronda Whitaker Tags: Business of Medicine Career Pediatrics PHM22 Source Type: research
COVID-19 and Stroke Trends in A Tertiary Care Center from South India -Our Monsoon Experience
Conclusion: Our study was a hypothesis-generating study with a limited number of patients. This study has reconfirmed the higher severity of the stroke, with a higher mRS score and mortality during the pandemic, especially among COVID-19-positive stroke patients.
Source: Neurology India - October 21, 2022 Category: Neurology Authors: Dileep Ramachandran Githin Benoy George Praveen Panicker R Aravind MK Suresh Thomas Iype Source Type: research
