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Nutrition: Flavonoids

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Total 135 results found since Jan 2013.

Natural Compounds as Medical Strategies in the Prevention and Treatment of Psychiatric Disorders Seen in Neurological Diseases
Psychiatric disorders are frequently encountered in many neurological disorders, such as Alzheimer’s and Parkinson diseases along with epilepsy, migraine, essential tremors, and stroke. The most common comorbid diagnoses in neurological diseases are depression and anxiety disorders along with cognitive impairment. Whether the underlying reason is due to common neurochemical mechanisms or loss of previous functioning level, comorbidities are often overlooked. Various treatment options are available, such as pharmacological treatments, cognitive-behavioral therapy, somatic interventions, or electroconvulsive therapy. Howev...
Source: Frontiers in Pharmacology - May 13, 2021 Category: Drugs & Pharmacology Source Type: research

Habitual flavonoid intake and ischemic stroke incidence in the Danish Diet, Cancer, and Health Cohort
CONCLUSIONS: These findings suggest that moderate habitual consumption of healthy flavonoid-rich foods is associated with a lower risk of ischemic stroke and further investigation is therefore warranted.PMID:33963737 | DOI:10.1093/ajcn/nqab138
Source: Am J Clin Nutr - May 8, 2021 Category: Nutrition Authors: Benjamin H Parmenter Frederik Dalgaard Kevin Murray Aedin Cassidy Catherine P Bondonno Joshua R Lewis Kevin D Croft Cecilie Kyr ø Gunnar Gislason Augustin Scalbert Anne Tj ønneland Jonathan M Hodgson Nicola P Bondonno Source Type: research

Molecules, Vol. 26, Pages 2495: The Role of Resveratrol in Human Male Fertility
do E. Calogero Resveratrol (RSV) (3,4′,5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer’s disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore...
Source: Molecules - April 24, 2021 Category: Chemistry Authors: Laura M. Mongio ì Sarah Perelli Rosita A. Condorelli Federica Barbagallo Andrea Crafa Rossella Cannarella Sandro La Vignera Aldo E. Calogero Tags: Review Source Type: research

Pinocembrin attenuates hemorrhagic transformation after delayed t-PA treatment in thromboembolic stroke rats by regulating endogenous metabolites
In this study, we investigated the effect of pinocembrin on t-PA-induced HT and the potential biomarkers for HT after t-PA thrombolysis, thereby improving the prognosis of stroke. Electrocoagulation-induced thrombotic focal ischemic rats received intravenous infusion of t-PA (10 mg/kg) 6 h after ischemia. Administration of pinocembrin (10 mg/kg, iv) prior t-PA infusion significantly decreased the infarct volume, ameliorated t-PA-induced HT, and protected blood-brain barrier. Metabolomics analysis revealed that 5 differential metabolites in the cerebral cortex and 16 differential metabolites in serum involved in amino acid ...
Source: Acta Pharmacologica Sinica - April 16, 2021 Category: Drugs & Pharmacology Authors: Ling-Lei Kong Li Gao Ke-Xin Wang Nan-Nan Liu Cheng-di Liu Guo-Dong Ma Hai-Guang Yang Xue-Mei Qin Guan-Hua Du Source Type: research

Dietary Flavonoids and Cardiovascular Disease: A Comprehensive Dose –Response Meta‐Analysis
ConclusionThe results of this study provide evidence of potential cardiovascular benefits of a flavonoid ‐rich diet.
Source: Molecular Nutrition and Food Research - February 25, 2021 Category: Food Science Authors: Agnieszka Micek, Justyna Godos, Daniele Del Rio, Fabio Galvano, Giuseppe Grosso Tags: Research Article Source Type: research

Seaweed Intake and Risk of Cardiovascular Disease: The Circulatory Risk in Communities Study (CIRCS).
CONCLUSIONS: We found an inverse association between seaweed intake and risk of total stroke, especially that from cerebral infarction, among Japanese men. PMID: 33597328 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - February 21, 2021 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Carthamin yellow improves cerebral ischemia ‑reperfusion injury by attenuating inflammation and ferroptosis in rats.
Carthamin yellow improves cerebral ischemia‑reperfusion injury by attenuating inflammation and ferroptosis in rats. Int J Mol Med. 2021 Apr;47(4): Authors: Guo H, Zhu L, Tang P, Chen D, Li Y, Li J, Bao C Abstract Carthamin yellow (CY), a flavonoid compound extracted from safflower, has been reported to attenuate cardiac ischemia and reperfusion injury. However, whether CY could ameliorate ischemic stroke is not completely understood. In the present study, the preventive effects of CY on experimental ischemic stroke were investigated using middle cerebral artery occlusion (MCAO) model rats. Neurologi...
Source: International Journal of Molecular Medicine - February 13, 2021 Category: Molecular Biology Authors: Guo H, Zhu L, Tang P, Chen D, Li Y, Li J, Bao C Tags: Int J Mol Med Source Type: research

Dietary Flavonoids and Cardiovascular Disease: A Comprehensive Dose ‐Response Meta‐Analysis
ConclusionThe results of this study provide evidence of potential cardiovascular benefits of a flavonoid ‐rich diet.This article is protected by copyright. All rights reserved
Source: Molecular Nutrition and Food Research - February 9, 2021 Category: Food Science Authors: Agnieszka Micek, Justyna Godos, Daniele Del Rio, Fabio Galvano, Giuseppe Grosso Tags: Research Article Source Type: research

Neurodegenerative diseases and Flavonoids: Special reference to kaempferol.
Abstract Neurodegenerative diseases like Alzheimer's disease, Parkinson's disease, Huntington's disease, Multiple Sclerosis and Ischemic stroke have become a major health problem worldwide. Pre-clinical studies have demonstrated the beneficial effects of flavonoids on neurodegenerative diseases and suggesting them to be used as therapeutic agents. Kaempferol is found in many plants such as tea, beans, broccoli,strawberriesand has neuroprotective effects against the development of many neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease and Huntington's disease. The present study summarizest...
Source: CNS and Neurological Disorders Drug Targets - January 29, 2021 Category: Drugs & Pharmacology Authors: Rahul, Siddique YH Tags: CNS Neurol Disord Drug Targets Source Type: research

Consumption of flavonoid-rich fruits, flavonoids from fruits, and stroke risk: a prospective cohort study.
Abstract We sought to examine the prospective associations of specific fruit consumption, in particular flavonoid-rich fruit (FRF) consumption, with the risk of stroke and subtypes of stroke in a Japanese population. A study followed a total of 39,843 men and 47,334 women aged 44-76 years, and free of cardiovascular disease, diabetes, and cancer at baseline since 1995 and 1998 to the end of 2009 and 2012, respectively. Data on total and specific FRF consumption for each participant were obtained using a self-administrated food frequency questionnaire. The hazard ratios (HRs) of stroke in relation to total and spec...
Source: The British Journal of Nutrition - January 29, 2021 Category: Nutrition Authors: Gao Q, Dong JY, Cui R, Muraki I, Yamagishi K, Sawada N, Iso H, Tsugane S, Japan Public Health Center-based Prospective Study Group Tags: Br J Nutr Source Type: research