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Pentraxin 3 in Cardiovascular Disease
Giuseppe Ristagno1*, Francesca Fumagalli1, Barbara Bottazzi2, Alberto Mantovani2,3,4, Davide Olivari1, Deborah Novelli1 and Roberto Latini1
1Department of Cardiovascular Research, Mario Negri Institute for Pharmacological Research IRCCS, Milan, Italy
2Humanitas Clinical and Research Center-IRCCS, Milan, Italy
3Humanitas University, Milan, Italy
4The William Harvey Research Institute, Queen Mary University of London, London, United Kingdom
The long pentraxin PTX3 is a member of the pentraxin family produced locally by stromal and myeloid cells in response to proinflammatory signals and microbial moieties. The p...
Source: Frontiers in Immunology - April 16, 2019 Category: Allergy & Immunology Source Type: research
Platelet Count Predicts Adverse Clinical Outcomes After Ischemic Stroke or TIA: Subgroup Analysis of CNSR II
Conclusion: In ischemic stroke or TIA patients with platelet count within normal range, platelet count may be a qualified predictor for long-term recurrent stroke, mortality, and poor functional outcome.
Introduction
Platelets exert a critical role in the pathogenesis of atherosclerotic complications of cardio-cerebrovascular disease, contributing to thrombus formation, and embolism (1, 2). Previous literature reported that platelets of various size and density are produced by megakaryocytes of different size and stages of maturation in different clinical conditions, suggesting various platelet patterns in differen...
Source: Frontiers in Neurology - April 11, 2019 Category: Neurology Source Type: research
Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research
Superbugs, Anti-Vaxxers Make WHO ’ s List Of 10 Global Health Threats
(CNN) — From climate change to superbugs, the World Health Organization has laid out 10 big threats to our global health in 2019.
And unless these threats get addressed, millions of lives will be in jeopardy.
Here’s a snapshot of 10 urgent health issues, according to the United Nations’ public health agency:
Not vaccinating when you can
One of the most controversial recent health topics in the US is now an international concern.
“Vaccine hesitancy — the reluctance or refusal to vaccinate despite the availability of vaccines — threatens to reverse progress made in tackling vaccine-prevent...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 21, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Local TV Source Type: news
Cancers, Vol. 11, Pages 111: A Review on a Deep Learning Perspective in Brain Cancer Classification
uca Saba
Jasjit S. Suri
A World Health Organization (WHO) Feb 2018 report has recently shown that mortality rate due to brain or central nervous system (CNS) cancer is the highest in the Asian continent. It is of critical importance that cancer be detected earlier so that many of these lives can be saved. Cancer grading is an important aspect for targeted therapy. As cancer diagnosis is highly invasive, time consuming and expensive, there is an immediate requirement to develop a non-invasive, cost-effective and efficient tools for brain cancer characterization and grade estimation. Brain scans using magnetic resonanc...
Source: Cancers - January 18, 2019 Category: Cancer & Oncology Authors: Gopal S. Tandel Mainak Biswas Omprakash G. Kakde Ashish Tiwari Harman S. Suri Monica Turk John R. Laird Christopher K. Kwaku A. Annabel A. Ankrah N. N. Khanna B. K. Madhusudhan Luca Saba Jasjit S. Suri Tags: Review Source Type: research
High-Fiber Diet Linked To Lower Risk Of Death And Chronic Illness
(CNN) — People who eat diets that are high in fiber have lower risk of death and chronic diseases such as stroke or cancer compared with people with low fiber intake, a new analysis found.
Dietary fiber includes plant-based carbohydrates such as whole-grain cereal, seeds and some legumes. Fiber’s health benefits have been recorded “by over 100 years of research,” Andrew Reynolds, a researcher at the University of Otago in New Zealand, wrote in an email. He is co-author of the new meta-analysis of existing research, which was published Thursday in the journal The Lancet.
The research shows that high...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 11, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN fiber Local TV Source Type: news
Want to Prevent the Deadliest Diseases? Eat More Fiber
If you want to eat something for better health, make it fiber. That’s the advice from nutrition experts and the latest national dietary guidelines.
Now, a large new review of studies on fiber, published in the Lancet, shows just how beneficial fiber can be. The nutrient substantially lowers the risk of at least four diseases—many of which don’t even directly relate to the gut.
Compared to those who ate less fiber, people who ate more fiber lowered their risk of heart disease, stroke, type 2 diabetes and colon cancer, as well as their risk of dying early from any cause, by 15% to 30%. And the more dietary ...
Source: TIME: Health - January 10, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Cancer Diet/Nutrition healthytime Heart Disease Source Type: news
Image-based screening.
Abstract
Screening is a special issue in medical questions concerning disease prevention. Preconditions for screening are clearly defined by the World Health Organization. High prevalence, effectiveness of therapy, availability of accepted test procedure and consensus concerning the economic concerns are necessary for successful implementation of a screening program. Preventive diagnostic studies can only be understood if one is familiar with the statistical terms sensitivity, specificity, prevalence, incidence and bias (especially overdiagnosis and lead time bias). Aspects of radiation protection are especially...
Source: Der Radiologe - December 14, 2018 Category: Radiology Authors: Layer G Tags: Radiologe Source Type: research
Effectiveness of pharmacotherapy for smoking cessation: protocol for umbrella review and quality assessment of systematic reviews
DiscussionThe World Health Organization recommends treatment of tobacco dependence as one approach in its comprehensive tobacco control policy. To date, many trials and systematic reviews have been conducted to assess the effectiveness of pharmacotherapy for smoking cessation. Therefore, the findings of the umbrella review will improve clinical decision-making and be used as a baseline for future studies.Systematic review registrationPROSPERO CRD42017080906
Source: Systematic Reviews - November 24, 2018 Category: International Medicine & Public Health Source Type: research
‘ Meat Taxes ’ Would Save Lives And Cut Health Care Costs, Study Says
(CNN) — It would drive up the price of your barbecue but a global “meat tax” could save 220,000 lives and cut health care bills by $41 billion each year, according to a new study.
The numbers are based on evidence that links meat consumption to increased risk of heart disease, cancer, stroke and diabetes.
Three years ago, the World Health Organization declared red meat such as beef, lamb and pork to be carcinogenic when eaten in processed forms, including sausages, bacon and beef jerky.
Health officials have also declared that unprocessed red meat like steak and burgers are “probably” carcinog...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 7, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Offbeat Local TV Meat Source Type: news
Chronic illnesses: UN stands up to stop 41 million avoidable deaths per year
“Heart disease, stroke, cancer, diabetes, chronic Lyme disease, depression” – just some of the illnesses outlined by World Health Organization (WHO) chief Dr. Tedros Ghebreyesus, who drove home the danger by asking delegates to stand up, when they heard the name of an illness that had killed someone they loved: One by one, every single person in the room, got to their feet.
Source: UN News Centre - Health, Poverty, Food Security - September 27, 2018 Category: International Medicine & Public Health Source Type: news
U.N.: Excessive Drinking Killed Over 3 Million People Worldwide in 2016
(GENEVA) — Drinking too much alcohol killed more than 3 million people in 2016, mostly men, the World Health Organization said.
The U.N. health agency also warned that current policy responses are not sufficient to reverse trends predicting an increase in consumption over the next 10 years.
In a new report Friday, the agency said that about 237 million men and 46 million women faced alcohol problems, with the highest prevalence in Europe and the Americas. Europe has the highest global per capita alcohol consumption, even though it has already dropped by 10 percent since 2010.
Around a third of alcohol-related deaths...
Source: TIME: Health - September 22, 2018 Category: Consumer Health News Authors: Associated Press Tags: Uncategorized Alcohol onetime Source Type: news
The Promise of Digital Health in the Fight against Noncommunicable Diseases
September 06, 2018Could activity trackers help stem the global tide of hypertension?Noncommunicable diseases, or NCDs, kill 41 million people around the world each year, including 15 million whodie prematurely because of them. But did you know that 85% of these premature deaths occur in low- and middle-income countries?Also known as chronic diseases, NCDs include pulmonary/respiratory disease, diabetes, cancer, and cardiovascular disease. They are often preventable and develop gradually. There are several risk factors for NCDs, including hyperlipidemia, hyperglycemia, obesity, and unhealthy lifestyle and diet.But the bi...
Source: IntraHealth International - September 6, 2018 Category: International Medicine & Public Health Authors: mnathe Source Type: news
An Egg A Day Might Reduce Your Risk Of Heart Disease, Study Says
In this study however, they didn’t assess the risk of developing diabetes, which may be because diabetes is a newer disease in the Chinese population and there is not good documentation of who has it,” Richard said. Still, she noted, “this will be very important data for helping develop dietary prevention guidelines in China.”
Cardiovascular disease, which takes the lives of 17.7 million people every year, is the leading cause of death and disability worldwide, according to the World Health Organization. Cardiovascular disease causes nearly a third — 31% — of all global deaths each year....
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - May 22, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Eggs Heart Disease Local TV Source Type: news
The Causes of Maternal Mortality are Changing and Preventable.
This article is protected by copyright. All rights reserved.
PMID: 29673041 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - April 19, 2018 Category: OBGYN Authors: Stokes MJ, Wilkinson JP Tags: BJOG Source Type: research
