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Source: Pediatric Neurology

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Total 229 results found since Jan 2013.

‘Wrong side’ tongue deviation in hemiplegia due to stroke
A previously healthy 10 year-old right-handed boy presented with acute left arm and left leg weakness soon after exercises during football practice. Examination revealed dense left-sided hemiplegia sparing the face associated with ipsilateral tongue deviation (Figure 1 A), vertical upbeat nystagmus, left sided hyporeflexia and a left Babinski reflex. Magnetic resonance imaging (MRI) of brain and cervical cord showed restricted diffusion and the corresponding hypointesity in ADC (apparent diffusion coefficient) at left caudal anterior medulla and left antero-lateral cervico-medullary junction due to acute ischemic infarctio...
Source: Pediatric Neurology - March 14, 2015 Category: Neurology Authors: Riddhiben Patel, Aimee F. Luat, Kumar Rajamani Tags: Visual Diagnosis Source Type: research

“Wrong Side” Tongue Deviation in Hemiplegia from Stroke
A previously healthy 10-year-old right-handed boy presented with acute left arm and leg weakness soon after football practice. Examination revealed dense left hemiplegia sparing the face associated with ipsilateral tongue deviation (Fig A), vertical upbeat nystagmus, left hyporeflexia, and a left Babinski reflex. Magnetic resonance imaging of the brain and cervical cord showed restricted diffusion and the corresponding hypointensity in the apparent diffusion coefficient at the left caudal anterior medulla and left anterolateral cervicomedullary junction resulting from acute ischemic infarction in left anterior spinal arte...
Source: Pediatric Neurology - March 14, 2015 Category: Neurology Authors: Riddhiben Patel, Aimee F. Luat, Kumar Rajamani Tags: Visual Diagnosis Source Type: research

Clock Drawing in Children with Peri-Natal Stroke
Children with peri-natal stroke may show evidence of contralateral spatial neglect. The goal of this study was to determine whether a clock drawing task commonly used in adults to identify neglect would be effective in detecting neglect in children with peri-natal stroke.
Source: Pediatric Neurology - January 31, 2015 Category: Neurology Authors: Omid Yousefian, Angela O. Ballantyne, Alex Doo, Doris A. Trauner Tags: Original Articles Source Type: research

Pathophysiology and neuroprotection of global and focal perinatal brain injury: lessons from animal models
Arterial ischemic stroke occurs most frequently in term newborns than in the elderly, and brain immaturity affects mechanisms of ischemic injury and recovery. The susceptibility to injury of the brain was assumed to be lower in the perinatal period as compared to childhood. This concept was recently challenged by clinical studies showing marked motor disabilities after stroke in neonates, with the severity of motor and cortical sensory deficits similar in both perinatal and childhood ischemic stroke.
Source: Pediatric Neurology - January 30, 2015 Category: Neurology Authors: Luigi Titomanlio, David Fernández-López, Lucilla Manganozzi, Raffaella Moretti, Zinaida S. Vexler, Pierre Gressens Tags: Topical Review Source Type: research

Internuclear opthalmoplegia as a symptom of ischemic stroke in a child with patent foramen ovale (PFO)
A 16-year-old previously healthy female presented with sudden diplopia and dizziness. Both symptoms appeared on the day of admission, soon after waking up in the morning. The day before admission she complained of a headache followed by transient numbness in the right half of her face. Neurological examination revealed typical signs of internuclear ophthalmoplegia (limitated adduction in the left eye with a horizontal nystagmus in the right eye during attempted right gaze, Fig. 1a,b,c,d).
Source: Pediatric Neurology - December 31, 2014 Category: Neurology Authors: Maria Mazurkiewicz-Bełdzińska, Marta Szmuda, Marta Zawadzka Tags: Visual Diagnosis Source Type: research

Internuclear Opthalmoplegia as a Symptom of Ischemic Stroke in a Girl With Patent Foramen Ovale
A previously healthy 16-year-old girl presented with sudden-onset diplopia and dizziness. Both symptoms appeared on the day of admission, soon after awakening in the morning. The day before admission, she complained of a headache followed by transient numbness in the right half of her face. Neurological examination revealed an internuclear ophthalmoplegia (limited adduction in the left eye with a horizontal nystagmus in the right eye during attempted right gaze, Figure A-D).
Source: Pediatric Neurology - December 31, 2014 Category: Neurology Authors: Maria Mazurkiewicz-Bełdzińska, Marta Szmuda, Marta Zawadzka Tags: Visual Diagnosis Source Type: research

Hemiparesis and epilepsy are associated with worse reported health status following unilateral stroke in children
Perinatal and childhood stroke result in neurologic impairment in the majority of survivors, but less is known about patient and parent perception of function following stroke in children. Our aim was to characterize parent-proxy and child-reported health status in children following unilateral arterial ischemic stroke or intraparenchymal hemorrhage.
Source: Pediatric Neurology - December 2, 2014 Category: Neurology Authors: Sabrina E. Smith, Gray Vargas, Andrew J. Cucchiara, Sarah J. Zelonis, Lauren A. Beslow Tags: Original Articles Source Type: research

Two Cases of Cerebrovascular Accidents in Neonates With Incontinentia Pigmenti
We report two infants who were diagnosed as IP at birth and subsequently developed seizures because of cerebral infarcts at 6 and 27 days of age. These patients remind physicians to consider the risk of stroke in neonates with IP.
Source: Pediatric Neurology - November 26, 2014 Category: Neurology Authors: Wen-Chien Tsai, Yu-Wen Cheng, Chih Cheng Chen, Pi-Lien Hung Tags: Letter to the Editor Source Type: research

Early Wallerian degeneration in a neonate with MCA stroke
A 23-day-old female with history of transposition of great arteries, ventricular septal defect, pulmonary stenosis and placement of right modified Blalock-Taussig shunt complicated by thrombosis at age 9 days of life presented with episodes of upper extremity extension and gasping respirations concerning for seizure. Brain MRI demonstrated an extensive, acute right middle carotid artery (MCA) territory stroke with occlusion of the right proximal MCA. There was also a small left frontal stroke. Diffusion restriction abnormalities with simultaneous presence of hyperintensity on T2 sequences in the cotricospinal tract consist...
Source: Pediatric Neurology - October 31, 2014 Category: Neurology Authors: Olga D. Taraschenko, Charles Nichter, John Pugh Tags: Visual Diagnosis Source Type: research

Early Wallerian Degeneration in a Neonate With Middle Carotid Artery Stroke
A 23-day-old girl with a history of transposition of the great arteries, ventricular septal defect, pulmonary stenosis, and placement of right modified Blalock-Taussig shunt complicated by thrombosis at age 9 days of life presented with episodes of upper extremity extension and gasping respirations concerning for seizure. Brain magnetic resonance imaging demonstrated an extensive, acute right middle carotid artery territory stroke with occlusion of the right proximal middle carotid artery. There was also a small left frontal stroke.
Source: Pediatric Neurology - October 31, 2014 Category: Neurology Authors: Olga D. Taraschenko, Charles Nichter, John A. Pugh Tags: Visual Diagnosis Source Type: research

An atypical case of Canavan disease with stroke-like presentation
Canavan disease is an autosomal recessive leukodystrophy caused by a deficiency of aspartoacylase. The disease has a severe course, with death occurring in the first few years of life. Atypical patients with mild courses have been reported, but acute presentations similar to stroke have not been well-described.
Source: Pediatric Neurology - October 25, 2014 Category: Neurology Authors: Katherine E. Delaney, Stephen F. Kralik, Bryan E. Hainline, Meredith R. Golomb Tags: Clinical Observations Source Type: research

Stroke in Children with Cardiac Disease: Report from the International Pediatric Stroke Study Group Symposium
Cardiac disease is a leading cause of stroke in children, yet limited data support the current stroke prevention and treatment recommendations. A multi-disciplinary panel of clinicians was convened in February 2014 by the International Pediatric Stroke Study group to identify knowledge gaps and prioritize clinical research efforts for children with cardiac disease and stroke.
Source: Pediatric Neurology - October 4, 2014 Category: Neurology Authors: Adriane J. Sinclair, Christine K. Fox, Rebecca N. Ichord, Christopher S. Almond, Timothy J. Bernard, Lauren A. Beslow, Anthony K.C. Chan, Michael Cheung, Gabrielle deVeber, Michael M. Dowling, Neil Friedman, Therese M. Giglia, Kristin P. Guilliams, Tilman Tags: Topical Review Source Type: research

Out of Pocket Costs for Childhood Stroke: The Impact of Chronic Illness Upon Parents' Pocketbooks
We described the out-of-pocket costs families encountered in the first year after a child’s ischemic stroke.
Source: Pediatric Neurology - September 25, 2014 Category: Neurology Authors: Patricia Plumb, Eric Seiber, Michael M. Dowling, JoEllen Lee, Timothy J. Bernard, Gabrielle deVeber, Rebecca Ichord, Rachel Bastian, Warren D. Lo Tags: Original Articles Source Type: research

Out-of-Pocket Costs for Childhood Stroke: The Impact of Chronic Illness on Parents' Pocketbooks
We described the out-of-pocket costs families encountered in the first year after a child's ischemic stroke.
Source: Pediatric Neurology - September 25, 2014 Category: Neurology Authors: Patricia Plumb, Eric Seiber, Michael M. Dowling, JoEllen Lee, Timothy J. Bernard, Gabrielle deVeber, Rebecca N. Ichord, Rachel Bastian, Warren D. Lo Tags: Original Article Source Type: research

Perinatal Arterial Ischemic Stroke: Presentation, Risk Factors, Evaluation, and Outcome
Perinatal arterial ischemic stroke (AIS) is as common as large vessel arterial ischemic stroke in adults and leads to significant morbidity. Perinatal AIS is the most common cause of cerebral palsy and can lead to cognitive and behavioral difficulties that are amortized over a lifetime.
Source: Pediatric Neurology - August 14, 2014 Category: Neurology Authors: Laura L. Lehman, Michael J. Rivkin Source Type: research