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Source: Pediatric Neurology

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Total 229 results found since Jan 2013.

Consensus-Based Evaluation of Outcome Measures in Pediatric Stroke Care: A Toolkit
Following a pediatric stroke, outcome measures selected for monitoring functional recovery and development vary widely. We sought to develop a toolkit of outcome measures that are currently available to clinicians, possess strong psychometric properties, and are feasible for use within clinical settings. A multidisciplinary group of clinicians and scientists from the International Pediatric Stroke Organization comprehensively reviewed the quality of measures in the domain ’s global performance, motor and cognitive function, language, quality of life, and behavior and adaptive functioning described in pediatric stroke populations.
Source: Pediatric Neurology - January 18, 2023 Category: Neurology Authors: Samantha J. Feldman, Lauren A. Beslow, Ryan J. Felling, Laura A. Malone, Michaela Waak, Stuart Fraser, Nihal Bakeer, Jo Ellen M. Lee, Victoria Sherman, Melissa M. Howard, Beth Anne Cavanaugh, Robyn Westmacott, Lori C. Jordan Tags: Review Article Source Type: research

SARS-CoV-2 Infection and Increased Risk for Pediatric Stroke
There is an increased risk of stroke in adults with severe acute respiratory syndrome coronavirus 2 (coronavirus disease 2019 [COVID-19]) infection, but whether there is a similar association with stroke in children is unclear. Our objective was to determine whether there is a correlation between COVID-19 infection, multisystem inflammatory syndrome in children (MIS-C), and pediatric ischemic stroke.
Source: Pediatric Neurology - November 19, 2022 Category: Neurology Authors: MaryGlen J. Vielleux, Shanna Swartwood, Dan Nguyen, Karen E. James, Bree Barbeau, Joshua L. Bonkowsky Tags: Research Paper Source Type: research

Neonatal arterial ischemic stroke secondary to carotid artery dissection: a case report and systematic literature review
Carotid artery (CA) dissection is a rare aetiology of neonatal arterial ischemic stroke (NAIS). Diagnosis is challenging due to low level of suspicion and difficult interpretation of neonatal vascular studies.
Source: Pediatric Neurology - October 28, 2022 Category: Neurology Authors: Laura Baggio, Margherita Nosadini, Maria Federica Pelizza, Jacopo Norberto Pin, Anna Zarpellon, Clarissa Tona, Giorgio Perilongo, Paolo Simioni, Irene Toldo, Giacomo Talenti, Stefano Sartori Tags: Research Paper Source Type: research

Novel presentation of hemiplegic migraine in a patient with Cockayne syndrome
Cockayne Syndrome is a rare DNA repair disorder marked by premature aging, poor growth, and intellectual disability. Neurologic complications such as seizures, movement disorder, and stroke have been reported. To our knowledge, hemiplegic migraine has not been reported in association with Cockayne Syndrome.
Source: Pediatric Neurology - October 27, 2022 Category: Neurology Authors: Jennifer Carroll, Lisa Pabst, Daniel C. Koboldt, Samuel J. Franklin, Samantha Choi, Richard K. Wilson, Warren Lo Tags: Short Communication Source Type: research

Characteristics of Moyamoya Syndrome in Pediatric Patients with Neurofibromatosis Type 1
Moyamoya syndrome (MMS) is a progressive cerebral arteriopathy with increased incidence in children with neurofibromatosis type 1 (NF1). Despite the potential for significant neurological morbidity including stroke, little is known about the natural history and no guidelines exist for screening and management of NF1-associated MMS.
Source: Pediatric Neurology - June 4, 2022 Category: Neurology Authors: Stephanie N. Brosius, Arastoo Vossough, Michael J. Fisher, Shih-Shan Lang, Lauren A. Beslow, Brandon J. George, Rebecca Ichord Tags: Research Paper Source Type: research

Acute and delayed cerebrovascular injury from gunshot to the head in a 12-year-old child during the COVID-19 pandemic
We present a child shot during the pandemic who had significant acute and delayed cerebrovascular injury, but no stroke, likely due to medical mangement.
Source: Pediatric Neurology - February 10, 2022 Category: Neurology Authors: Meredith R. Golomb, Juan G. Tejada, Katrina A. Ducis, Mesha L. Martinez Tags: Short Communication Source Type: research

Multimodal Neurologic Monitoring in Children with Acute Brain Injury
Children with acute neurologic illness are at high risk of mortality and long-term neurologic disability. Severe traumatic brain injury, cardiac arrest, stroke, and central nervous system infection are often complicated by cerebral hypoxia, hypoperfusion, and edema, leading to secondary neurologic injury and worse outcome. Due to the paucity of targeted neuroprotective therapies for these conditions, management emphasizes close physiologic monitoring and supportive care. In this review, we will discuss advanced neurologic monitoring strategies in pediatric acute neurologic illness, emphasizing the physiologic concepts underlying each tool.
Source: Pediatric Neurology - February 1, 2022 Category: Neurology Authors: Jennifer C. Laws, Lori C. Jordan, Lindsay M. Pagano, John C. Wellons, Michael S. Wolf Tags: Review Article Source Type: research

Acute Large Vessel Ischemic Stroke in Patients with COVID-19 Related Multisystem Inflammatory Syndrome
Acute ischemic stroke (AIS) is rare in children and diagnosis is often delayed. Neurological involvement may occur in multisystem inflammatory syndrome in children (MIS-C), but very few cases of AIS in patients with MIS-C have been reported.
Source: Pediatric Neurology - September 25, 2021 Category: Neurology Authors: Jaimie Chang, Zachary Bulwa, Hannah Breit, Laurel J. Cherian, James J. Conners, Sarah Y. Song, Rima M. Dafer Tags: Research Paper Source Type: research

Acute Large Vessel Ischemic Stroke in Patients With COVID-19 –Related Multisystem Inflammatory Syndrome
Acute ischemic stroke (AIS) is rare in children, and diagnosis is often delayed. Neurological involvement may occur in multisystem inflammatory syndrome in children (MIS-C), but very few cases of AIS in patients with MIS-C have been reported.
Source: Pediatric Neurology - September 25, 2021 Category: Neurology Authors: Jaimie Chang, Zachary Bulwa, Hannah Breit, Laurel J. Cherian, James J. Conners, Sarah Y. Song, Rima M. Dafer Tags: Clinical Observation Source Type: research

Stroke Following Acute Chest Syndrome in a Child With Sickle Cell Disease: A Possible Novel Mechanism
We present a child with hemoglobin SC-type sickle cell disease (SCD-SC) who developed a large posterior circulation stroke following an episode of acute chest syndrome (ACS). This case demonstrates that large infarcts can occur in sickle cell genotypes typically associated with less severe phenotypes.
Source: Pediatric Neurology - September 17, 2021 Category: Neurology Authors: Nicole E. Kendel, Warren D. Lo, Anthony D. Villella Tags: Clinical Letter Source Type: research

Stroke Following Acute Chest Syndrome in a Child with Sickle Cell Disease: A Possible Novel Etiology
We present a child with hemoglobin SC type sickle cell disease (SCD-SC) who developed a large posterior circulation stroke following an episode of acute chest syndrome (ACS). This case demonstrates that large infarcts can occur in sickle cell genotypes typically associated with less severe phenotypes.
Source: Pediatric Neurology - September 17, 2021 Category: Neurology Authors: Nicole E. Kendel, Warren D. Lo, Anthony D. Villella Tags: Short Communication Source Type: research

Capacity Building for Primary Stroke Prevention Teams in Children Living with Sickle Cell Anemia in Africa
We describe capacity-building strategies in conjunction with two National Institutes of Health-funded primary stroke prevention trials (a feasibility trial and phase III randomized controlled trial) with initial hydroxyurea treatment for children with SCA and abnormal transcranial Doppler (TCD) velocities in Nigeria.
Source: Pediatric Neurology - September 3, 2021 Category: Neurology Authors: Djamila L. Ghafuri, Brittany Covert Greene, Bilya Musa, Awwal Gambo, Abdulrasheed Sani, Shehu Abdullahi, Binta J. Widil, Halima Bello-Manga, Safiya Gambo, Matin Ghafuri, Holly Cassell, Kathleen Neville, Fenella Kirkham, Adetola A. Kassim, Muktar H. Aliyu, Tags: Research Paper Source Type: research

Threatening Blindness in a Child With Typical Hemolytic Uremic Syndrome
Hemolytic uremic syndrome (HUS) is the most common cause of acute kidney failure in children younger than five years. Central nervous system involvement occurs in 15% of patients, with clinical manifestations including confusion, coma, seizures, stroke, and cortical blindness. Ocular involvement in children with HUS is rare, but retinal and choroidal hemorrhages as well as ischemic retinopathy due to thrombotic microangiopathic lesions have been documented.
Source: Pediatric Neurology - June 24, 2021 Category: Neurology Authors: Ana ïs Corgier-Pattberg, Marie Beylerian, Stephanie Clave, Mathilde Cailliez, Benoit Testud, Beatrice Desnous Tags: Short Communication Source Type: research

Threatening blindness in a child with typical haemolytic uremic syndrome
Hemolytic uremic syndrome (HUS) is the most common cause of acute kidney failure in children under five years of age, following a gastrointestinal infection with Shiga toxin-producing Escherichia coli (STEC) and characterized by the presence of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury (1). Central Nervous System (CNS) involvements are seen in 15% of cases, with clinical manifestations ranging from obnubilation to coma, seizures, stroke, and cortical blindness (2).
Source: Pediatric Neurology - June 24, 2021 Category: Neurology Authors: Ana ïs Corgier-Pattberg, Marie Beylerian, Stephanie Clave, Mathilde Cailliez, Benoit Testud, Beatrice Desnous Tags: Short Communication Source Type: research

Acute ischemic stroke in a pediatric patient due to osteosarcoma embolus
We report a 6-year-old with an ischemic stroke due to osteosarcoma embolus.
Source: Pediatric Neurology - April 22, 2021 Category: Neurology Authors: Min Ye Shen, Amol Mehta, Rebecca J. Zylber, Alice Lee, Randolph S. Marshall, Arezou Heshmati Tags: Short Communication Source Type: research