Early Wallerian degeneration in a neonate with MCA stroke

A 23-day-old female with history of transposition of great arteries, ventricular septal defect, pulmonary stenosis and placement of right modified Blalock-Taussig shunt complicated by thrombosis at age 9 days of life presented with episodes of upper extremity extension and gasping respirations concerning for seizure. Brain MRI demonstrated an extensive, acute right middle carotid artery (MCA) territory stroke with occlusion of the right proximal MCA. There was also a small left frontal stroke. Diffusion restriction abnormalities with simultaneous presence of hyperintensity on T2 sequences in the cotricospinal tract consistent with early Wallerian degeneration were noted.
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Visual Diagnosis Source Type: research