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Source: Canadian Journal of Cardiology
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Total 265 results found since Jan 2013.
Early vs Late Surgery for Patients With Endocarditis and Neurological Injury: A Systematic Review and Meta-analysis
ConclusionsAvailable observational data support delaying surgery by 7-14 days if possible in IE complicated by ischemic stroke and> 21 days in hemorrhagic stroke to decrease perioperative mortality and neurological exacerbation rates. Randomized trials are needed for definitive guidance.RésuméIntroductionLe moment de l’intervention chirurgicale lors d’une endocardite infectieuse (EI) accompagnée d’événements neurologiques reste controversé. Les lignes directrices pertinentes de la Société reposent chacune sur un petit nombre d’études observationnelles. La présente méta-analyse a été conçue pour recher...
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research
Effects of Riociguat on Right Ventricular Remodelling in Chronic Thromboembolic Pulmonary Hypertension Patients: A Prospective Study
ConclusionsRiociguat treatment was associated with increased RV stroke volume index and trends for improvement in myocardial remodelling in patients with CTEPH. A larger clinical study is warranted to observe the therapeutic benefits of riociguat on RV remodelling.RésuméContexteLes effets du traitement par le riociguat sur le métabolisme, la perfusion et le débit du ventricule droit (VD) chez les patients atteints d’hypertension pulmonaire thromboembolique chronique (HPTC) sont inconnus. Dans la présente étude, nous analysons les changements aux ventriculaires droits associés au traitement par le riociguat.Méthod...
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research
Reply to Green et al.—Elevated Incidence of Atrial Fibrillation and Stroke in Patients With Atrial Flutter: A Population-Based Study
Publication date: September 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 9Author(s): Lorne J. Gula, Damian P Redfearn, Krista B. Jenkyn, Britney Allen, Allan C. Skanes, Peter Leong-Sit, Salimah Z. Shariff
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research
The association of kidney function and albuminuria with the risk and outcomes of syncope: A population-based cohort study
ConclusionsA lower eGFR and higher ACR are associated with a higher risk of a hospital encounter for syncope, and of related complications among individuals of an advanced age.
Source: Canadian Journal of Cardiology - August 29, 2018 Category: Cardiology Source Type: research
Antithrombotic Therapy for Atrial Fibrillation and Coronary Disease de-Mystified
Publication date: Available online 20 August 2018Source: Canadian Journal of CardiologyAuthor(s): Jason G. Andrade, Marc W. Deyell, Graham C. Wong, Laurent MacleABSTRACTAtrial fibrillation (AF) is a progressive chronic disease characterized by exacerbations and periods of remission. It is estimated that up to 20-30% of those with AF also have coronary artery disease (CAD), and 5-15% will require percutaneous coronary intervention (PCI). In patients with concomitant AF and CAD, management remains challenging and requires a careful and balanced assessment of the risk of bleeding against the anticipated impact on ischemic out...
Source: Canadian Journal of Cardiology - August 21, 2018 Category: Cardiology Source Type: research
The importance and future of population screening for atrial fibrillation
Publication date: Available online 17 August 2018Source: Canadian Journal of CardiologyAuthor(s): Seung Yong Shin, Gregory Y.H. LipAbstractAtrial fibrillation (AF) is a common and progressive heart rhythm disorder that causes structural, functional and electrical remodelling of the heart. Although we do not fully understand AF yet, this arrhythmia is one clinical feature of a syndrome that is represented by irregularly irregular atrial rhythm accompanied by progressive atrial structural and functional remodelling. Although ischemic stroke, most feared complication of AF, can be prevented by anticoagulation, asymptomatic or...
Source: Canadian Journal of Cardiology - August 18, 2018 Category: Cardiology Source Type: research
Determining the Optimal Systolic Blood Pressure for Hypertensive Patients: A Network Meta-analysis
ConclusionsSBP <130 mmHg is associated with a lower risk of stroke and major adverse cardiovascular events. Further lowering to <120 mmHg can be considered to reduce stroke risk if the therapy is tolerated. Long-term SBP should not exceed 150 mmHg because of increased risk of myocardial infarction and cardiac deaths.
Source: Canadian Journal of Cardiology - August 10, 2018 Category: Cardiology Source Type: research
Prevalence and Outcomes of Percutaneous Coronary Interventions for Ostial Chronic Total Occlusions: Insights from a Multicenter CTO Registry
ConclusionsOstial CTOs can be recanalized with similar success rates as non-ostial CTOs, but are more complex and more likely to require retrograde crossing, and may be associated with numerically higher risk for major in-hospital complications.
Source: Canadian Journal of Cardiology - July 31, 2018 Category: Cardiology Source Type: research
Acute coronary syndromes and heart failure CCU utilization and outcomes in teaching and community hospitals: A national population based analysis
Publication date: Available online 29 July 2018Source: Canadian Journal of CardiologyAuthor(s): Sanam Verma, Padma Kaul, Meng Lin, Justin A. Ezekowitz, David A. Zygun, Christopher B. Fordyce, Tracy Y. Wang, Finlay A. McAlister, Sean van DiepenAbstractAcute coronary syndromes (ACS) and heart failure (HF) are the leading diagnoses in patients admitted to critical care units (CCU). Little is known about the differences between CCU resource utilization and outcomes across hospital types. The Canadian Institute for Health Information was used to identify patients hospitalized with a primary diagnosis of an ACS or HF. CCUs were ...
Source: Canadian Journal of Cardiology - July 29, 2018 Category: Cardiology Source Type: research
Variability in Non–Vitamin K Antagonist Oral Anticoagulants Dose Adjustment in Atrial Fibrillation Patients With Renal Dysfunction: The Influence of Renal Function Estimation Formulae
ConclusionsMDRD and CKD-EPI eGFR fail to correctly identify a significant proportion of patients who require NOAC dose adjustment, limiting their clinical utility. Cockcroft-Gault eCrCl should be calculated for all patients in whom a NOAC is being prescribed.RésuméContexteL’administration d’un nouvel anticoagulant oral non-antivitamine K (NACO) nécessite un ajustement de la dose en fonction des paramètres rénaux. La mesure de la fonction rénale la plus communément utilisée est le taux de filtration glomérulaire estimé (TFGe) selon la formule « Modified Diet in Renal Disease » (TFGe MDRD) ou « Chronic Kidne...
Source: Canadian Journal of Cardiology - July 24, 2018 Category: Cardiology Source Type: research
Sex-Specific Differences in Outcome of Transcatheter or Surgical Aortic Valve Replacement
ConclusionsThis nation-wide analysis of sex-specific outcomes after aortic-valve replacement procedures showed that women are higher-risk for bleeding, but lower-risk for stroke, mechanical ventilation, and TF-TAVR mortality. Understanding these differences and their basis may help improve outcomes.RésuméContexteLes différences anatomiques et celles au niveau des caractéristiques initiales entre patients de sexe masculin et féminin présentant une sténose valvulaire aortique pourraient influencer l’issue après un remplacement valvulaire aortique par voie chirurgicale et transcathéter. Nous avons évalué l’effe...
Source: Canadian Journal of Cardiology - July 24, 2018 Category: Cardiology Source Type: research
Invasive Hemodynamics and Rejection Rates in Patients With Cardiac Sarcoidosis After Heart Transplantation
ConclusionsPatients with CS have similar post-transplant hemodynamics as patients without CS, without evidence of right ventricular dysfunction or pulmonary hypertension. Neither significant rejection nor recurrence of sarcoid in the allograft was observed in this cohort of patients with CS. Survival is similar between patients with CS and those without CS. Heart transplant is a viable strategy in selected patients with CS with excellent outcomes.RésuméIntroductionLa transplantation cardiaque orthotopique (TCO) est de plus en plus utilisée lors d’insuffisance cardiaque terminale liée à une sarcoïdose cardiaque (SC)...
Source: Canadian Journal of Cardiology - July 24, 2018 Category: Cardiology Source Type: research
New Insights into the Use of Cardiac Magnetic Resonance Imaging to Guide Decision-Making in AF Management
Publication date: Available online 12 July 2018Source: Canadian Journal of CardiologyAuthor(s): Tarek Zghaib, Saman NazarianAbstractRecent advances in cardiac magnetic resonance (CMR) imaging acquisition techniques have enabled the visualization of thin atrial myocardium with high temporal and spatial resolution and have the potential to shift atrial fibrillation (AF) management paradigms. Late gadolinium-enhancement (LGE) CMR can non-invasively identify atrial arrhythmogenic scar substrates and has been shown to spatially correlate with low-voltage areas. Immediately post-ablation, a combination of native T1-weighted, LGE...
Source: Canadian Journal of Cardiology - July 12, 2018 Category: Cardiology Source Type: research
Integrating Individuals with Stroke into Cardiac Rehabilitation Following Traditional Stroke Rehabilitation: Promoting a Continuum of Care
Publication date: Available online 11 July 2018Source: Canadian Journal of CardiologyAuthor(s): Susan Marzolini, R. KinUnstructured AbstractIndividuals following stroke are at a high risk for a repeat stroke and for complications related to coronary artery disease. Indeed, stroke and coronary artery disease share many of the same risk factors. Unfortunately, patients become sedentary after stroke leading to cardiorespiratory deconditioning as well as muscle atrophy and weakness that leads to deterioration in metabolic, cardiorespiratory, and functional health. Access to intensive secondary prevention programs with a struct...
Source: Canadian Journal of Cardiology - July 12, 2018 Category: Cardiology Source Type: research
Reply to Kea et al.—Stroke Prevention for High-Risk Atrial Fibrillation in the Emergency Setting: Differences Between Canada and the US
Publication date: July 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 7Author(s): Clare L. Atzema
Source: Canadian Journal of Cardiology - July 10, 2018 Category: Cardiology Source Type: research
