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Source: Canadian Journal of Cardiology

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Total 265 results found since Jan 2013.

Elevated Incidence of Atrial Fibrillation and Stroke in Patients With Atrial Flutter —A Population-Based Study
Conclusions Patients with isolated atrial flutter develop AF and stroke at a higher rate than the general population. Catheter ablation reduces but does not eliminate future AF incidence and stroke risk and continued anticoagulation after successful atrial flutter ablation might therefore be warranted.
Source: Canadian Journal of Cardiology - May 26, 2018 Category: Cardiology Source Type: research

Factors Influencing Oral Anticoagulation Prescription for Patients Presenting to Emergency Departments With Atrial Fibrillation and Flutter
Publication date: June 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 6 Author(s): Robert J.H. Miller, Derek S. Chew, Saman Rezazadeh, Sheila Klassen, Payam Pournazari, Eddy Lang, F. Russell Quinn Atrial fibrillation and atrial flutter (AF/AFL) are associated with an increased risk of stroke and systemic embolism. However, many patients are not started on guideline-recommended oral anticoagulation (OAC). We determined factors associated with initiation of OAC in eligible patients presenting to emergency departments. This retrospective cohort included patients with electrocardiogram (ECG)-documented AF/AFL pr...
Source: Canadian Journal of Cardiology - May 26, 2018 Category: Cardiology Source Type: research

Blood Pressure –Lowering Targets in Patients With Diabetes Mellitus
Publication date: May 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 5 Author(s): Alexander A. Leung, Raj S. Padwal Diabetes is a highly prevalent medical condition that commonly coexists with hypertension. The presence of diabetes and hypertension significantly increases the risk of adverse cardiovascular events. Although compelling evidence exists from randomized controlled trials demonstrating that blood pressure (BP) reduction effectively prevents cardiovascular complications, optimal BP targets remain uncertain and continue to be the subject of ongoing controversy. Until recently, most major clinical pr...
Source: Canadian Journal of Cardiology - May 4, 2018 Category: Cardiology Source Type: research

The Potential Effects of New Stent Platforms for Coronary Revascularization in Patients With Diabetes
Publication date: May 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 5 Author(s): Gustavo S. Guandalini, Sripal Bangalore Coronary artery disease in patients with diabetes mellitus (DM) is characterized by extensive atherosclerosis, longer lesions, and diffuse distal disease. Consequently, these patients have worse outcomes after coronary revascularization, regardless of the modality used. Traditionally, coronary artery bypass grafting (CABG) has been regarded as more effective than percutaneous coronary intervention (PCI) in patients with DM, likely because of more complete revascularization and protection ...
Source: Canadian Journal of Cardiology - May 4, 2018 Category: Cardiology Source Type: research

Applicability of the Systolic Blood Pressure Intervention Trial (SPRINT) to the Canadian Population
Conclusions If fully implemented, intensive systolic BP lowering to < 120 mm Hg in SPRINT-eligible high-risk individuals would substantially increase the proportion of Canadian adults receiving BP treatment initiation or intensification.
Source: Canadian Journal of Cardiology - May 4, 2018 Category: Cardiology Source Type: research

Prognostic Role of Hypertensive Response to Exercise in Patients With Repaired Coarctation of Aorta
Conclusions HRE can occur even in the setting of normal blood pressure at rest, and it is a risk factor for CAE. We speculate that patients with HRE represent a high-risk group of patients who, presumably, have occult, advanced vascular dysfunction. CPET can identify these patients. The benefit of intensive antihypertension therapy needs to be confirmed.
Source: Canadian Journal of Cardiology - May 4, 2018 Category: Cardiology Source Type: research

Variability In NOAC Dose Adjustment In Atrial Fibrillation Patients With Renal Dysfunction: The Influence Of Renal Function Estimation Formulae
Conclusion MDRD and CKD-EPI eGFR fails to correctly identify a significant proportion of patients that require NOAC dose adjustment, limiting their clinical utility. Cockcroft-Gault eCrCl should be calculated for all patients in whom a NOAC is being prescribed. Teaser While glomerular filtration rate is the most common estimates of renal function employed in practice the landmark stroke prevention trials use of the Cockcroft-Gault creatinine clearance equation to determine drug eligibility and dose adjustment. In a large cohort of patients with non-dialysis dependent chronic kidney disease and atrial fibrillation the use o...
Source: Canadian Journal of Cardiology - April 26, 2018 Category: Cardiology Source Type: research

Sex-specific differences in outcome of transcatheter or surgical aortic valve replacement
Conclusions This nation-wide analysis of sex-specific outcomes after aortic-valve replacement procedures showed that women are higher-risk for bleeding, but lower-risk for stroke, mechanical ventilation, and TF-TAVR mortality. Understanding these differences and their basis may help improve outcomes. Teaser We analyzed baseline characteristics and outcomes of all isolated TAVR or SAVR procedures performed in Germany between 2011 and 2014. In comparison to male patients, females were preferentially treated with TF-TAVR rather than SAVR due to their generally older age and higher EuroSCORE. Females suffered from more relevan...
Source: Canadian Journal of Cardiology - April 13, 2018 Category: Cardiology Source Type: research

Invasive Hemodynamics and Rejection Rates in Patients with Cardiac Sarcoidosis After Heart Transplantation
Conclusions CS patients have similar post-transplant hemodynamics as non-CS patients, without evidence of RV dysfunction or pulmonary hypertension. No significant rejection nor recurrence of sarcoid in the allograft were observed in this cohort of patients with CS. Survival is similar between CS and non-CS patients. Heart transplant is a viable strategy in selected CS patients with excellent outcomes. Teaser Orthotopic heart transplant (OHT) is utilized for end-stage heart failure due to cardiac sarcoidosis (CS). There is a lack of data on long-term outcomes. We explored changes in hemodynamics, allograft rejection and sur...
Source: Canadian Journal of Cardiology - April 7, 2018 Category: Cardiology Source Type: research

Sex Differences in the Incidence and Outcomes of Newly Diagnosed Atrial Fibrillation-Related Stroke
Publication date: April 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 4 Author(s): J.D. Edwards, A. Micieli, A.Y.X. Yu, J. Fang, D. Gladstone
Source: Canadian Journal of Cardiology - March 21, 2018 Category: Cardiology Source Type: research

A Narrative Inquiry into Women ’s Cardiovascular Health as Promoted by the Heart and Stroke Foundation of Canada (HSFC) to the Public Through Facebook.
Publication date: April 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 4 Author(s): C.A. Gonsalves, K.R. McGannon, A. Pegoraro, R.J. Schinke
Source: Canadian Journal of Cardiology - March 21, 2018 Category: Cardiology Source Type: research

Living with Stroke: A Woman ’s Experience of Stroke From Hospital to Home and Beyond
Publication date: April 2018 Source:Canadian Journal of Cardiology, Volume 34, Issue 4 Author(s): D. Kandola, D. Banner, B. Croome
Source: Canadian Journal of Cardiology - March 21, 2018 Category: Cardiology Source Type: research

Automated 3-dimensional single beat real-time volume color-flow Doppler echocardiography in children: a validation study of right and left heart flows
Conclusions Stroke volume determined by automated RT-3D-VCFDE is feasible in children and in the right side of the heart. This technique potentially provides a non-invasive alternative to historically invasively acquired hemodynamic data and to cardiac magnetic resonance imaging. Teaser The newest technologic advancements of real-time three-dimensional volume color-flow Doppler echocardiography (3D-RT-VCFDE) are single beat acquisition and automated analysis. Automated 3D-RT-VCFDE has been validated with cardiac magnetic resonance imaging in the left heart of adults. In this study, automated 3D-RT-VCFDE is shown to be feas...
Source: Canadian Journal of Cardiology - March 13, 2018 Category: Cardiology Source Type: research

Vascular plugging for the enlarging pulmonary arteriovenous malformation in a patient with idiopathic pulmonary artery hypertension
Publication date: Available online 2 March 2018 Source:Canadian Journal of Cardiology Author(s): Kae-Woei Liang, Chi-Yao Huang, Sheng-Ling Jan, Kuo-Yang Wang The coexistence of idiopathic pulmonary artery hypertension (IPAH) with pulmonary arteriovenous malformation (PAVM) is challenging because while the PAVM causes hypoxia and polycythemia with potential thrombotic complications, closing the PAVM increases pulmonary-artery pressure. Here, we report on a lady with PAVM and IPAH who, within two years of diagnosis, had an ischemic stroke, PAVM enlargement from 20x20x30 mm to 30x40x40 mm and oximetry decrease to 90%. Trans-...
Source: Canadian Journal of Cardiology - March 2, 2018 Category: Cardiology Source Type: research

Hypertension Canada ’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children
Publication date: Available online 1 March 2018 Source:Canadian Journal of Cardiology Author(s): Kara A. Nerenberg, Kelly B. Zarnke, Alexander A. Leung, Kaberi Dasgupta, Sonia Butalia, Kerry McBrien, Kevin C. Harris, Meranda Nakhla, Lyne Cloutier, Mark Gelfer, Maxime Lamarre-Cliche, Alain Milot, Peter Bolli, Guy Tremblay, Donna McLean, Raj S. Padwal, Karen C. Tran, Steven Grover, Simon W. Rabkin, Gordon W. Moe, Jonathan G. Howlett, Patrice Lindsay, Michael D. Hill, Mike Sharma, Thalia Field, Theodore H. Wein, Ashkan Shoamanesh, George K. Dresser, Pavel Hamet, Robert J. Herman, Ellen Burgess, Steven E. Gryn, Jean C. Grégo...
Source: Canadian Journal of Cardiology - March 2, 2018 Category: Cardiology Source Type: research