Sex-specific differences in outcome of transcatheter or surgical aortic valve replacement

Conclusions This nation-wide analysis of sex-specific outcomes after aortic-valve replacement procedures showed that women are higher-risk for bleeding, but lower-risk for stroke, mechanical ventilation, and TF-TAVR mortality. Understanding these differences and their basis may help improve outcomes. Teaser We analyzed baseline characteristics and outcomes of all isolated TAVR or SAVR procedures performed in Germany between 2011 and 2014. In comparison to male patients, females were preferentially treated with TF-TAVR rather than SAVR due to their generally older age and higher EuroSCORE. Females suffered from more relevant bleeding, but required less ventilation and after adjustment had a lower stroke risk. In-hospital mortality was slightly decreased in females undergoing TF-TAVR after adjustment.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research