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Source: Clinical Neurophysiology

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Total 347 results found since Jan 2013.

EP 20. Contralesional Cathodal tDCS versus dual-tDCS for decreasing upper limb spasticity in chronic stroke individuals: A clinical and neurophysiological study
Different transcranial direct current stimulation (tDCS) paradigms have been implemented to treat post-stroke spasticity, but discordant results have been reported.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: A. Del Felice, V. Daloli, S. Masiero, P. Manganotti Tags: ePoster Presentations – Noninvasive Neuromodulation I Source Type: research

EP 10. Home-based motor imagery training in chronic stroke supported by neurofeedback: A feasibility study
Chronic hemiparesis of an upper limp following stroke has been related to an over-involvement of the ipsilateral hemisphere that inhibits use of the affected limb. Interventions helping to shift back this altered lateralization have been suggested to positively affect upper limp functional recovery. One such intervention is the combination of motor imagery (MI) supported by EEG neurofeedback. However, cortical reorganization requires highly intensive practice. In this feasibility study this was achieved by implementing a mobile EEG neurofeedback system.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: C. Kranczioch, C. Zich, C. Schweinitz, J. Meekes, S. Debener Source Type: research

EP 9. Prevalence, clinical characteristics and long-term course of headache in patients with stroke (multicenter study of DMKG)
Headache in association with stroke is a symptom not at all differentiated and investigated in Germany. According to previous data, it seems to be a common problem, but usually other symptoms of stroke are predominating. Furthermore, the treatment is focused on acute therapy of ischemic stroke followed by rehabilitation. However, headaches in subarachnoid hemorrhage as a special type of stroke represents the leading clinical symptom and thus also be diagnostically significant. Headache in stroke should be classified as symptomatic headache (IHS 6.1 –6.2).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: S. Dietrich, A. D üring, D. Rothkirch, F. Filippopulos, O. Eren, T. Dresler, A. Straube, G. Goßrau, T. Kraya Source Type: research

EP 8. The role of contralesional motor areas in early motor recovery – evidence from event-related (“online”) TMS
TMS studies examining the role of the unaffected hemisphere in motor function after stroke have mainly focused on the contralesional primary motor cortex (M1), revealing both supporting (Lotze et al., 2006; Rehme et al., 2011) as well as disturbing (Vollmer et al., 2015; Nowak et al., 2008) influence for recovery of function. However, the relevance of other contralesional motor areas for paretic hand function has rarely been examined, especially with respect to motor recovery in the first days and weeks after stroke.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: K. Lemberg, C. Tscherpel, L. Hensel, M. Vollmer, L. Volz, G. Fink, C. Grefkes Source Type: research

EP 6. Longitudinal resting state functional connectivity patterns in the early phase of recovery from Aphasia in temporoparietal stroke
Poststroke aphasia recovery evolves in space and time. Substantial language improvements can be observed within the first days after stroke. However, underlying changes in the functional status of the language network during the acute phase remain to be demonstrated.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: J. Klingbeil, A. Stockert, M. Wawrzyniak, K. Wrede, D. Saur Source Type: research

EP 5. Decrement of the effect of neuromuscular electrical stimulation over time in chronic stroke patients
Neuromuscular electrical stimulation (NMES) has been applied as one rehabilitative treatment option in stroke patients (Quandt and Hummel, 2014) and a meta-analysis recently showed its positive effects on motor recovery (Stein et al., 2015). One major challenge in stroke patients, especially severely impaired, is the opening of the hand due to extensor weakness accompanied by flexor spasticity. Here, NMES could provide assistance and substitute lost function. Studies in healthy controls have shown, however, that the rapid onset of muscle fatigue is a critical limitation for practical use.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: F. Quandt, J. Feldheim, J.C. Loitz, D. Wolff, M. Rohm, R. Rupp, W.H. Krautschneider, F.C. Hummel Source Type: research

EP 4. Recruitment of premotor cortices in subacute stroke patients – A longitudinal fMRI study
In order to investigate changes in functional representation of hand movement after stroke we used functional magnetic resonance imaging (fMRI) during an active motor task of the affected hand before and after a three week comprehensive motor training.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: U. Horn, S. Roschka, K. Eyme, A.D. Walz, T. Platz, M. Lotze Source Type: research

EP 3. Impact of energy expenditure and cognitive function on long- term outcome after stroke
Stroke leads to lesion-induced deficits like hemiparesis and aphasia. Furthermore patients suffer from low aerobic endurance and high energy expenditure of walking as well as from cognitive decline. Motor and Activity of daily living (ADL) rehabilitation might be negatively impacted by these factors. Here, our aim was to evaluate how (a) energy expenditure of walking and (b) cognitive function in the subacute phase after stroke correlate to long-term outcomes (gait speed, activities of daily life).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: T. Rackoll, C. Werner, A. Fl öel Source Type: research

EP 2. Pyramidal tract FA predicts motor outcome in subacute stroke patients after a three week period of arm ability training for ADL-relevant hand motor tests
Outcome prediction after motor stroke for the acute to subacute phase can be consulted for individual therapy modification. For the outcome of severely impaired patients the intactness of the pyramidal tract descending from the lesioned hemisphere (ipsilesional; i) has been described as an important parameter for upper limb strength as a measure of motor outcome (Stinear et al., 2012). In addition, in chronic stroke fractional anisotrophy (FA) of the pyramidal tract is predictive for hand motor impairment in strength (Lindenberg et al., 2010).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: M. Domin, S. Roschka, U. Horn, T. Platz, M. Lotze Tags: ePoster Presentations – Stroke Source Type: research

EP 1. Brain activity after acute left hemispheric stroke in imitation and tool associated actions
Apraxia, a disorder of higher motor control, frequently leads to impaired tool use or imitation capacities due to left hemispheric lesions. However, despite similar lesion size or location, patients present with different apraxic deficits thus different early reorganization mechanism may be assumed. To understand the impaired praxis network after stroke on a functional level, we correlated behavioral performance in imitation and tool use tasks with activation patterns in fMRI of 47 acute left-hemispheric stroke patients.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: A. Dressing, L. Beume, C.S. M. Schmidt, D. K ümmerer, T. Bormann, I. Mader, M. Rijntjes, C.P. Kaller, C. Weiller, M. Martin Tags: ePoster Presentations – Stroke Source Type: research

EPV 19. Dissociable regions for recognition and execution of conceptual and spatio-temporal action characteristics in acute stroke patients
The ability to recognize and respond to actions performed by others is fundamental for a wide range of activities involving social interactions. However, despite an enormous number of functional imaging studies, a precise delineation of the brain regions crucial for distinct aspects of action recognition has remained elusive. Moreover, the degree of overlap between regions involved in active action performance is controversial.To elucidate these issues, 98 acute stroke patients (68 male, age meanSD, 6513 years) were examined in the acute period after stroke (meanSD 4.42 days after symptom onset).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: M. Martin, A. Dressing, L. Beume, T. Bormann, I. Mader, M. Rijntjes, C.P. Kaller, C. Weiller Source Type: research

FV 10. Motor imagery supported by neurofeedback: Age-related changes in EEG and fNIRS lateralization patterns
Motor imagery (MI) supported by neurofeedback has been suggested as a promising add-on therapy to facilitate motor recovery after stroke. Though the main target group for such an intervention are elderly patients, research so far is largely focused on young, healthy adults. We therefore examined in two experiments the influence of age on the neural correlates of motor imagery (MI) in a real-time electroencephalogram (EEG) neurofeedback framework.In a first experiment MI-induced activity was studied in MI and neurofeedback na ïve young (N=39; 18–30years) and elderly (N=36;>55years) healthy adults.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: C. Zich, S. Debener, L.-C. Chen, C. Kranczioch Tags: Orals – Neuromodulation Source Type: research

FV 1. Perilesional activation in poststroke language recovery
Poststroke aphasia recovery evolves in time. Increased perilesional activity associated with treatment-related language improvements has been confirmed in the chronic phase (Fridriksson et al., 2011), but has not yet been systematically demonstrated during the early phases of stroke recovery. The pathophysiology of stroke suggests that perilesional reorganisation evolves within days, lasting for months after stroke, while increased neuronal excitability might provide a basis for perilesional neuroplasticity (Schiene et al., 1999).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: A. Stockert, J. Klingbeil, M. Wawrzyniak, K. Wrede, D. Saur Tags: Orals – Functional Imaging Source Type: research

EP 121. Motor sequence learning in patients with limb apraxia – The effects of long-term training
Recent studies show that limb apraxia is often not recognized as a higher motor impairment in patients suffering from a stroke. Because it is adversely affecting every-day life and personal independence, a successful rehabilitation of apraxia is critical for personal well-being (Cappa et al., 2005; Dovern et al., 2012). Yet, evidence of an effective treatment approach with long-lasting effects and generalization to untrained actions is still missing (Binkofski and Klann, 2013; Dovern et al., 2011).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: S. Reitze, M. Heister über, A. Karni, C. Gal, J. Doyon, B.R. King, J. Classen, J.- J. Rumpf, G. Buccino, J. Klann, F. Binkofski Source Type: research

71. Sturge –Weber syndrome+cortical dysplasia. A dual pathology case report
Sturge –Weber syndrome is a rare disorder that occurs with a frequency of approximately 1 per 50,000. The disease is characterized by an intracranial vascular anomaly like leptomeningeal angiomatosis. Facial cutaneous vascular malformations, seizures, and glaucoma are among the most common symptoms and s igns. The clinical course is highly variable and some children experience intractable seizures, mental retardation, and recurrent stroke-like episodes.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: Areli Rosario Suarez-Roman, Enoe Cruz-Martinez, Yokary Amor Mellado-Ortiz, Ernesto Ramirez-Navarrete, Paul Shkurovich-Bialik Source Type: research