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Source: Clinical Neurophysiology
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Total 347 results found since Jan 2013.
P 67 Electrophysiological correlates of language improvements after intensive language therapy in patients with chronic post-stroke aphasia
Aphasia affects approximately one third of all stroke patients and may lead to chronic disability. Effective neurorehabilitation programs focusing on improving speech and language in patients with post-stroke aphasia are essential. A better understanding of the neurobiological processes accompanying language deficits and rehabilitation may bear fruit in the advancement of neurorehabilitation programs.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: G. Lucchese, F. Pulverm üller, B. Stahl, F. Dreyer, B. Mohr Tags: Poster Source Type: research
P 66 Transcranial DC stimulation enhances recovery of swallowing function after stroke – a randomized clinical and MEG trial
Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation tool that has shown some potential to aid motor rehabilitation following stroke. In the present clinical and neuroimaging study we evaluated whether tDCS is able to speed up the recovery of swallowing function in acute dysphagic stroke patients. Besides relating clinical effects with neuroplastic changes in cortical swallowing processing we aimed to identify factors influencing treatment success.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: S. Suntrup-Kr üger, C. Ringmaier, P. Muhle, R. Dziewas Tags: Poster Source Type: research
P 65 Navigated repetitive transcranial magnetic stimulation – therapeutic use in early rehabilitation treatment after stroke
MRI navigated repetitive transcranial magnetic stimulation (nTMS) provides a new tool for neuromodulation – we report on its effects on recovery of brain function in a setting of inpatient rehabilitation early after stroke.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: C. Wedekind, H. Weber, P. Rieckmann Tags: Poster Source Type: research
P 4 Bioluminescence imaging visualizes osteopontin-induced neurogenesis and neuroblasts migration in the mouse brain after stroke
The phosphoglycoprotein osteopontin (OPN) is upregulated in the brain following cerebral ischemia, where is exerts neuroprotective properties. We previously demonstrated OPN to increase survival and proliferation of neural stem cells (NSC) in vitro and in vivo. In culture, OPN additionally promotes NSC migration as well as a neuronal differentiation fate. Based on these data, we hypothesized OPN to induce NSC migration as well as neurogenesis in vivo as well. We here aimed to establish and visualize these effects using non-invasive in vivo imaging.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: R. Rogall, A. Pikhovych, A. Bach, M. Hoehn, S. Couillard-Despres, G.R. Fink, M. Schroeter, M.A. Rueger Tags: Poster Source Type: research
PB 23 Factors predicting global cognitive ability 6month after stroke – preliminary results from the Phys-Stroke trial
Stroke is one of the most frequent causes of chronic and often severe language and motor impairments. Moreover, stroke increases the risk of developing cognitive impairments or even dementia over time (Pendlebury and Rothwell, 2009). Although recent studies investigated predictors of cognitive decline after stroke, several questions remain. In particular, it needs to be clarified whether therapies applied during the rehabilitation phase may reduce or even prevent cognitive decline.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: T. Rackoll, K. Prehn, C. N àjera, L. Doppelbauer, A. Flöel Tags: Poster Blitz Source Type: research
FV 13 Electrophysiological correlates of language recovery – an MEG study of neuroplasticity in chronic post stroke aphasia
Previous studies have demonstrated that efficient language and communication therapy in chronic post stroke aphasia leads to significant clinical language improvements (Pulverm üller et al., 2001) and promotes neuroplasticity. Brain areas frequently associated with functional restitution of language comprise perilesional sites in the left hemisphere (MacGregor et al., 2015) as well as right-hemispheric regions, homotopic to those lesioned in the left (Mohr et al., 2014). To date, however, the neuronal mechanisms underlying therapy-induced language changes and functional restitution are still largely unclear.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: B. Mohr, S. Difrancesco, L. MacGregor, Y. Shtyrov Tags: Free Lecture Source Type: research
P 167 The functional role of contralesional motor areas in the first days after stroke – an fMRI-guided online TMS-study
Neuroimaging studies in stroke patients with hemiparesis have shown altered brain activation in the contralesional hemisphere including the primary motor cortex (M1), dorsal premotor cortex (dPMC) and anterior intraparietal sulcus (aIPS) already in the first week after stroke (Rehme et al., 2011). The role of these regions for motor recovery is still under debate, with some studies suggesting a supportive influence (Lotze et al., 2006) while other point to a maladaptive role (Nowak et al., 2008).
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: L. Hensel, C. Tscherpel, J. Freytag, S. Ritter, M. Vollmer, L. Volz, G.R. Fink, C. Grefkes Tags: Poster Source Type: research
P 165 Incidence, clinical characteristics and longterm course of headache in patients with stroke (DMKG multicenter study)
Post stroke headache is a symptom which is generally not further differentiated. According to previous European and American studies, it is a common phenomenon. Nevertheless, other symptoms of stroke, such as palsy or aphasia, are dominating clinical assessments. However, the symptom “headache” can be an essential part of the clinical picture as in subarachnoid bleeding or cerebral venous thrombosis and it is unclear which risk factors modulate the symptoms and the occurrence of headache in stroke.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: S. Dietrich, A. D üring, D. Rothkirch, F. Filippopulos, O. Eren, T. Dresler, T. Buchwald, A. Straube, S. Zierz, G. Goßrau, T. Kraya Tags: Poster Source Type: research
P 164 Parietal stroke mimicking the Heidenhain variant of Creutzfeldt-Jakob Disease
The Heidenhain variant of Creutzfeldt-Jakob disease (CJD) is a rapidly progressive neurodegenerative disease with an occipito-parietal focus.It initially presents with visual disturbances such as visual agnosia or cortical blindness (Kropp et al., 1999).After presentation of early visual symptoms, rapid progression of dementia and death follows.While the Heidenhain variant matches neuropathological criteria of CJD, differential diagnosis from other neurological disorders using biomarkers from electroencephalography (EEG), magnetic resonance imaging (MRI), and cerebrospinal fluid (CSF) reveal low sensitivity and specificity...
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: D. Becker, D. Kramer, W. M üllges, K. Boelmans Tags: Poster Source Type: research
P 163 Combining TMS and EEG – a new tool to assess motor system integrity after stroke
Despite the wealth of neuroimaging studies regarding stroke pathophysiology and recovery after stroke, there is still a lack of clinically relevant biomarkers that allow to predict the potential of functional recovery and treatment response at individuals ’ level. Anovel approach is to test motor system integrity by means of combining transcranial magnetic stimulation (TMS) and electroencephalography (EEG). By recording TMS-evoked potentials (TEP), the cortical response to TMS, both local and network responses can be recorded and analyzed in indivi dual subjects (Rogasch and Fitzgerald, 2012; Ferreri, 2011).
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: C. Tscherpel, S. Dern, S. Bender, F. M üller-Dahlhaus, U. Ziemann, G.R. Fink, C. Grefkes Tags: Poster Source Type: research
P 162 Rhythmic Auditory Stimulation (RAS) as an additional treatment for chronic stroke patients in the outpatient setting: a randomized controlled trial
Rhythmic Auditory Stimulation (RAS) is a rhythmic sensory cueing to enhance gait patterns. Aim of the study was to research the effectiveness of RAS as an additional treatment for chronic stroke patients.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: A. Sch öler Tags: Poster Source Type: research
P 145 Deficient body structural description in apraxia
Apraxia is a common cognitive deficit after left hemisphere (LH) stroke. It has been suggested that a disturbed representation of the human body underlies apraxic deficits. Thus, we here tested the hypothesis that a deficient body structural description (BSD), i.e., a deficient representation of a body part ”s position (relative to a standard human body), contributes to apraxia, while controlling for a deficient semantic representation of the human body (body image, BI) and aphasia.A quantitative pointing task to assess putative BSD deficits and an apraxia assessment including imitation and pantomime tasks were applied t...
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: H. Salimi Dafsari, A. Dovern, G.R. Fink, P.H. Weiss Tags: Poster Source Type: research
S31 Structurally informed analyses of functional connectivity in stroke
Stroke is the leading cause of disability in industrialized countries, has a big impact on quality of life, and is of high socioeconomic relevance. Despite great advances of acute therapy – like thrombolysis and mechanical thrombectomy – approximately 50% of stroke survivors suffer from permanent neurological deficits, mostly because of structural and functional neural network failure.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Christian Gerloff Source Type: research
O-2-6-15. Immediate effects of anodal tDCS combined with patterned electrical stimulation on gait performance in patients with stroke
This study aimed to examine the immediate effects of anodal tDCS combined with PES on gait performance in patients with stroke. Twelve patients with subacute stroke participated in this double-masked, sham-controlled cross-over study. They randomly participated in the following sessions on separate days: (1) anodal tDCS+PES; (2) anodal tDCS+sham PES; (3) sham tDCS+PES.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Tomofumi Yamaguchi, Toshiyuki Fujiwara, Kazuhei Maeda, Tsuyoshi Tatemoto, Shigeo Tanabe, Yoko Takahashi, Katsuhiro Mizuno, Yoshihisa Masakado, Meigen Liu Source Type: research
P298 Can music enhance movement intention?
Active participation of patients themselves in rehabilitation is a vital factor for the stroke recovery. Since music can create positive emotion and sometimes trigger spontaneous movements, such as dancing, combination of music and rehabilitation might be beneficial in improving patients ’ mental and physical functions. To clarify the influence of music on human movement intention and to establish the significance of rehabilitation combined with music, we tested whether music may activate the cortical preparation of voluntary movement.
Source: Clinical Neurophysiology - August 17, 2017 Category: Neuroscience Authors: Yoshie Nakajima, Tatsuya Mima, Yoshiyuki Tadokoro Source Type: research
