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Source: Clinical Neurophysiology

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Total 347 results found since Jan 2013.

EP 2. Pyramidal tract FA predicts motor outcome in subacute stroke patients after a three week period of arm ability training for ADL-relevant hand motor tests
Outcome prediction after motor stroke for the acute to subacute phase can be consulted for individual therapy modification. For the outcome of severely impaired patients the intactness of the pyramidal tract descending from the lesioned hemisphere (ipsilesional; i) has been described as an important parameter for upper limb strength as a measure of motor outcome (Stinear et al., 2012). In addition, in chronic stroke fractional anisotrophy (FA) of the pyramidal tract is predictive for hand motor impairment in strength (Lindenberg et al., 2010).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: M. Domin, S. Roschka, U. Horn, T. Platz, M. Lotze Tags: ePoster Presentations – Stroke Source Type: research

EP 1. Brain activity after acute left hemispheric stroke in imitation and tool associated actions
Apraxia, a disorder of higher motor control, frequently leads to impaired tool use or imitation capacities due to left hemispheric lesions. However, despite similar lesion size or location, patients present with different apraxic deficits thus different early reorganization mechanism may be assumed. To understand the impaired praxis network after stroke on a functional level, we correlated behavioral performance in imitation and tool use tasks with activation patterns in fMRI of 47 acute left-hemispheric stroke patients.
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: A. Dressing, L. Beume, C.S. M. Schmidt, D. K ümmerer, T. Bormann, I. Mader, M. Rijntjes, C.P. Kaller, C. Weiller, M. Martin Tags: ePoster Presentations – Stroke Source Type: research

8. Evolution and recovery of motor function post-stroke
Conclusion: Intracortical disinhibition occurs in both hemispheres immediately following acute stroke that likely represent functionally relevant changes supporting the recovery process in stroke. Whilst changes in the lesioned hemisphere persisted over the period of recovery in all patients, contralesional intracortical hyperexcitability persisted in patients with cortical strokes and those with more severe baseline functional impairment, suggesting that ongoing contralesional network recruitment may be necessary for those patients who have significant disruptions to the integrity of ipsilesional motor pathways. The study...
Source: Clinical Neurophysiology - March 3, 2014 Category: Neuroscience Authors: William Huynh, Steve Vucic, Arun V. Krishnan, Cindy S.-Y. Lin, Matthew C. Kiernan Tags: Society Proceedings Source Type: research

P 219. Navigated repeated transcranial magnetic stimulation in stroke rehabilitation (randomized blind sham-controlled study), Preliminary results: safety and tolerability
Conclusion: Repeated nTMS is safe and effective add-method in motor post-stroke rehabilitation, but continuous study and forming protocols are necessary to validate this method.ClinicalTrials.gov Identifier: NCT01652677.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: M. Piradov, L. Chernikova, M. Tanashyan, A. Kadykov, A. Chervyakov, M. Nazarova, V. Gnezditsky, R. Konovalov, N. Savitskaya, P. Fedin, A. Suslin, M. Glebov, L. Dobrynina Tags: Society Proceedings Source Type: research

State of intracortical inhibitory interneuron activity in patients with chronic stroke
Conclusions: The state of intracortical inhibitory neuron activity depends on the state of motor function and lesion site even in chronic stroke patients with severe hemiparesis.Significance: The inhibitory system of the AH is involved in functional recovery of the paretic hand even in the chronic stage of stroke.
Source: Clinical Neurophysiology - September 5, 2012 Category: Neuroscience Authors: Kaoru Honaga, Toshiyuki Fujiwara, Tetsuya Tsuji, Kimitaka Hase, Junichi Ushiba, Meigen Liu Tags: Movement, Motor Control and Movement Disorders Source Type: research

IS 30. Predicting recovery of motor function after stroke-an essential role for TMS
Conclusions: TMS is a useful tool for predicting recovery of upper limb function after stroke, particularly in combination with clinical and imaging measures, as part of the PREP algorithm. The clinical benefits of tailoring rehabilitation based on the individual’s capacity for motor recovery will be discussed.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: C. Stinear, S.J. Ackerley, M.A. Petoe, P.A. Barber, W.D. Byblow Tags: Society Proceedings Source Type: research

P 78. The prognostic value of motor-evoked potentials in motor recovery and functional outcome after stroke – a systematic review of the literature
Conclusions: TMS may be helpful in prognosis of motor recovery and functional outcome in stroke patients, and may become additional tool in making decision about qualification to rehabilitation ward and length of rehabilitation process. However, further studies are necessary to determine the real value of this method. The interpretation of the results of our review was complicated by methodological variation between the included studies.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: J. Bembenek, K. Kurczych, M. Karlinski, A. Czlonkowska Tags: Society Proceedings Source Type: research

IS 30. Predicting recovery of motor function after stroke-an essential role for TMS
Conclusions: TMS is a useful tool for predicting recovery of upper limb function after stroke, particularly in combination with clinical and imaging measures, as part of the PREP algorithm. The clinical benefits of tailoring rehabilitation based on the individual’s capacity for motor recovery will be discussed.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: C. Stinear, S.J. Ackerley, M.A. Petoe, P.A. Barber, W.D. Byblow Tags: Society Proceedings Source Type: research

P 78. The prognostic value of motor-evoked potentials in motor recovery and functional outcome after stroke – a systematic review of the literature
Conclusions: TMS may be helpful in prognosis of motor recovery and functional outcome in stroke patients, and may become additional tool in making decision about qualification to rehabilitation ward and length of rehabilitation process. However, further studies are necessary to determine the real value of this method. The interpretation of the results of our review was complicated by methodological variation between the included studies.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: J. Bembenek, K. Kurczych, M. Karlinski, A. Czlonkowska Tags: Society Proceedings Source Type: research

120. Changing in effective cerebral connectivity during the acute phase of stroke: An EEG TMS study
This study demonstrated a clear modification in effective cortical connectivity during the acute phases of stroke. The EEG-TMS technique has proven useful in evaluating the modification of synaptic plasticity that occur in the acute phase of stroke, offering the opportunity to acquire information for prediction of the prognosis or new therapeutic approaches.
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: F. Giambattistelli, L. Tomasevic, F. Vernieri, F. Assenza, A. Pepe, F. Tecchio, P.M. Rossini Tags: Society Proceedings Source Type: research

Temporal evolution of event-related desynchronization in acute stroke: A pilot study
Conclusion: The two evolutions presumably reflect the reorganization of brain networks and functional recovery after acute stroke. The significant increase of ipsilesional Sm in patients with a good recovery suggests an important role of this hemisphere during recovery.Significance: Improved understanding of ERD in acute stroke may assist in prognostication and rehabilitation.
Source: Clinical Neurophysiology - December 2, 2013 Category: Neuroscience Authors: Chayanin Tangwiriyasakul, Rens Verhagen, Wim L.C. Rutten, Michel J.A.M. van Putten Tags: Cerebral Function and its Development Source Type: research

Corticomuscular coherence in acute and chronic stroke
Conclusions: The changes in CMC parameters in acute stroke could result from a temporary decrease in inhibition, which normalizes in the course of recovery. As all patients showed very good motor recovery, the modulation of CMC amplitude and frequency over time might thus reflect the process of motor recovery.Significance: We demonstrate for the first time the dynamical changes of corticomuscular interaction both at acute and chronic stage of stroke.
Source: Clinical Neurophysiology - December 6, 2013 Category: Neuroscience Authors: Katherina von Carlowitz-Ghori, Zubeyir Bayraktaroglu, Friederike U. Hohlefeld, Florian Losch, Gabriel Curio, Vadim V. Nikulin Tags: Movement, Motor Control and Movement Disorders Source Type: research

P 128. Predicting behavioural response to TDCS in chronic motor stroke
Transcranial direct current stimulation (TDCS) of primary motor cortex (M1) can transiently improve paretic hand function in chronic stroke. However, responses are variable so there is incentive to try to improve efficacy or to predict response in individual patients. Both excitatory (Anodal) stimulation of ipsilesional M1 and inhibitory (Cathodal) stimulation of contralesional M1 can speed simple reaction time. Here we tested whether combining these two effects simultaneously, by using a bilateral M1–M1 electrode montage, would improve efficacy. We tested the physiological efficacy of Bilateral, Anodal or Cathodal TDCS ...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: J. O’Shea, M.-H. Boudrias, C.J. Stagg, V. Bachtiar, J.U. Blicher, H. Johansen-Berg Tags: Society Proceedings Source Type: research

P 172. Focal tDCS in Chronic Stroke patients: A pilot study of physiological effects using TMS and concurrent EEG
We report results of MEPs, EEG, and motor behavior. We show, for the first time, that tDCS and EEG recording can be concurrently applied in stroke patients. Bilateral M1 stimulation using small Ag/AgCl electrodes is well tolerated and can augment corticospinal excitability in the affected hemisphere. In the literature, there is only one prior studying using concurrent EEG recording during cathodal tDCS in healthy subjects and two patients with epileptic encephalopathy (Faria et al., 2012). As far as we know, no studies have applied tDCS simultaneous with EEG recording in chronic stroke patients. We report the first study i...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: D. Boratyn, G. Ruffini, M. Cortes, A. Rykman, A. Medeiros, A. Pascual-Leone, D. Edwards Tags: Society Proceedings Source Type: research