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Source: Clinical Neurophysiology

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Total 347 results found since Jan 2013.

35. Association of robot-assisted rehabilitation and non-invasive brain stimulation to improve upper limb function in chronic stroke patients
Previous studies suggested that both robotic rehabilitation and non-invasive brain stimulation could produce improvement in chronic stroke patients. It is still unknown whether their combination can produce synergistic effects. We designed a proof-of-principle, double-blinded, semi-randomized, sham-controlled trial to assess the safety and efficacy of this combination.Twenty severe upper limb-impaired chronic stroke patients were randomized to robot-assisted therapy associated with real or sham cTBS, delivered for 10 working days.
Source: Clinical Neurophysiology - November 11, 2017 Category: Neuroscience Authors: F. Capone, G. Di Pino, G. Pellegrino, L. Florio, L. Zollo, D. Simonetti, F. Ranieri, N. Brunelli, M. Corbetto, S. Miccinilli, M. Bravi, S. Milighetti, E. Guglielmelli, S. Sterzi, V. Di Lazzaro Source Type: research

26. A randomized controlled cross-over double blind study protocol on THC/CBD oromucosal spray as an add-on therapy for post-stroke spasticity
Understand if cannabinoids (THC:CBD) are useful in reducing post-stroke spasticity using a neurophysiological quantitative measure as primary endpoint.We will recruit 50 patients with spasticity following stroke to take THC:CBD in a double blind placebo-controlled crossover study. Spasticity will be assessed with a numeric rating scale for spasticity, the modified Ashworth scale and with the electromyographic recording of the stretch reflex. The cardiovascular risk will be assessed prior to inclusion.
Source: Clinical Neurophysiology - November 11, 2017 Category: Neuroscience Authors: L. Marinelli, M. Balestrino, L. Mori, L. Puce, G. Rosa, L. Giorello, A. Curr à, F. Fattapposta, C. Serrati, C. Gandolfo, G. Abbruzzese, C. Trompetto Source Type: research

Symmetry of cortical planning for initiating stepping in sub-acute stroke
After stroke, many people exhibit altered movement patterns making normal performance of balance and walking difficult (Duncan et al., 1992). However, the influence of motor planning on performance of balance and walking post-stroke is not well understood. Motor planning is defined as the integration of sensory afferent information (Ghez et al., 1997), such as limb position and muscle force (Kandel et al., 2000), with a functional goal (Zimmermann et al., 2012) to generate a movement (Peters et al., 2015).
Source: Clinical Neurophysiology - February 4, 2018 Category: Neuroscience Authors: Sue Peters, Tanya Ivanova, Bimal Lakhani, Lara A Boyd, W Richard Staines, Todd C Handy, S. Jayne Garland Source Type: research

P06-Cortical somatosensory processing after botulinum toxin therapy in post-stroke spasticity
In movement disorders, neurophysiology and functional MRI demonstrated abnormalities of sensorimotor processing, responding to peripheral botulinum toxin A (BoNT) treatment. We used Modified Ashworth scale (MAS) to assess spasticity and median nerve somatosensory evoked potentials (SEP) to study changes in sensorimotor cortical areas after BoNT therapy of post-stroke arm spasticity.Seventeen patients (10 men, 7 women, average age 60.2  years) with post-stroke arm spasticity were treated with BoNT into the affected muscles.
Source: Clinical Neurophysiology - March 13, 2018 Category: Neuroscience Authors: P. Hlu štík, T. Veverka, P. Hok, P. Otruba, A. Krobot, J. Zapletalová, P. Kaňovský Source Type: research

O-2-17. Influence of different types of orthoses on muscle synergy control during gait in stroke patients with hemiparesis
The purpose of this study was to verify the influence of lower limb orthoses on muscle synergy control during gait in stroke patients with hemiparesis. In four subjects with acute stroke, surface EMG signals from eight muscles of the paretic lower limb were measured during gait in two conditions (ankle foot orthosis; AFO or knee ankle foot orthosis; KAFO). The number of modules, muscle weightings and activation timing profile of each module were analyzed using non-negative matrix factorization. In two subjects (Fugl Meyer Assessment; FMA  > 20) who walked with mild assistance, three modules were identified during gait ...
Source: Clinical Neurophysiology - March 30, 2018 Category: Neuroscience Authors: Masanori Wakida, Kimihiko Mori, Yuta Chujo, Eiko Hirooka, Gwang-ho Kim, Koji Ohata, Kimitaka Hase Source Type: research

S21-1. A new analysis method using surface electromyography to assess finger function in patients with severe stroke
We have conducted our research into kinesthetic illusions induced by visual stimuli (KiNvis), which are sensations of being in motion that result from watching artificial images of the body part moving. Our previous studies revealed characteristic neural networks related to KiNvis; since then, we have initiated clinical studies adapting KiNvis in patients with stroke. In patients with severe stroke, it is often difficult to measure joint angles, because voluntary movement does not occur or simultaneous contraction of the agonist and antagonist muscles prevent controlled voluntary joint exercise.
Source: Clinical Neurophysiology - March 30, 2018 Category: Neuroscience Authors: Fuminari Kaneko Source Type: research

O-2-17. Influence of different types of orthoses on muscle synergy control during gait in stroke patients with hemiparesis
The purpose of this study was to verify the influence of lower limb orthoses on muscle synergy control during gait in stroke patients with hemiparesis. In four subjects with acute stroke, surface EMG signals from eight muscles of the paretic lower limb were measured during gait in two conditions (ankle foot orthosis; AFO or knee ankle foot orthosis; KAFO). The number of modules, muscle weightings and activation timing profile of each module were analyzed using non-negative matrix factorization. In two subjects (Fugl Meyer Assessment; FMA  > 20) who walked with mild assistance, three modules were identified during gait ...
Source: Clinical Neurophysiology - April 26, 2018 Category: Neuroscience Authors: Masanori Wakida, Kimihiko Mori, Yuta Chujo, Eiko Hirooka, Gwang-ho Kim, Koji Ohata, Kimitaka Hase Source Type: research

S21-1. A new analysis method using surface electromyography to assess finger function in patients with severe stroke
We have conducted our research into kinesthetic illusions induced by visual stimuli (KiNvis), which are sensations of being in motion that result from watching artificial images of the body part moving. Our previous studies revealed characteristic neural networks related to KiNvis; since then, we have initiated clinical studies adapting KiNvis in patients with stroke. In patients with severe stroke, it is often difficult to measure joint angles, because voluntary movement does not occur or simultaneous contraction of the agonist and antagonist muscles prevent controlled voluntary joint exercise.
Source: Clinical Neurophysiology - April 26, 2018 Category: Neuroscience Authors: Fuminari Kaneko Source Type: research

Diagnostic Value of Somatosensory Evoked Potential Changes During Carotid Endarterectomy for 30-Day Perioperative Stroke
Carotid Endarterectomy (CEA) is a standard surgical treatment in the secondary prevention of stroke performed in patients with both symptomatic and asymptomatic carotid stenosis (CS)(Malcharek et al. 2013), (Pennekamp et al. 2011), (Pulli et al. 2002), (Reinert et al. 2012). CEA is shown to benefit symptomatic and asymptomatic patients, when compared to medical management alone in the short term and long term due to decreased stroke. (Akhmedov et al. 2013), (Baton et al. 2007), (Floriani et al. 1989), (Hartmann et al.
Source: Clinical Neurophysiology - June 13, 2018 Category: Neuroscience Authors: Rajiv P. Reddy, Indraneel S. Brahme, Tejas Karnati, Jeffrey Balzer, Donald J. Crammond, Katherine Anetakis, Parthasarathy D. Thirumala Source Type: research

P60. Direct and long term influence of cardiovascular training on cognition in subacute stroke patients
Rehabilitation of cognitive deficits has been voted ‘#1 research priority’ for patients suffering from stroke (Saunders et al., 2014). Aerobic fitness training may modulate cognitive performance either by enhancing neuroplasticity or by increasing brain oxygenation. The majority of studies in this area have focused on motor function; its effect o n cognitive performance is not well understood yet. The current study therefore aims to evaluate the influence of aerobic fitness intervention on cognitive functions in subacute stroke patients, and tries to elucidate the mechanisms underlying this effect.
Source: Clinical Neurophysiology - July 10, 2018 Category: Neuroscience Authors: T. Rackoll, A. Nave, U. Grittner, H. Mousa, K. Villringer, M. Ebinger, A. Fl öel Source Type: research

FV12. Development of a diagnostic index test for stroke as a cause of vertigo, dizziness and imbalance in the emergency room: First results from the prospective EMVERT trial
Identifying stroke as a cause of acute vertigo, dizziness and imbalance in the emergency room is still a clinical challenge. The aim of the EMVERT trial was to develop a diagnostic index test to identify patients with the high risk to have a stroke as the cause of the balance symptoms.
Source: Clinical Neurophysiology - July 10, 2018 Category: Neuroscience Authors: A. Zwergal, K. M öhwald, H. Hadzhikolev, S. Bardins, T. Brandt, M. Dieterich, K. Jahn Source Type: research

S1-4. The effect of repetitive Transcranial Magnetic Stimulation (rTMS) in patients with intractable cervical dystonia and/or post-stroke central pain
In conclusion, rTMS is useful as one of the option in the treatment of intractable CD and CPSP.
Source: Clinical Neurophysiology - July 16, 2013 Category: Neuroscience Authors: Norihiro Muraoka, Minoru Shigemori, Fumihiko Koike, Masao Hiromatu, Keiko Suematu, Motohiro Morioka Tags: Society Proceedings Source Type: research

S5-5. Effects of repetitive transcranial magnetic stimulation with repetitive facilitation exercise in post-stroke patients
Repetitive magnetic stimulation (rTMS) induces functional and structural plasticity, while repetitive facilitation exercises (RFEs) promote the functional recovery of the hemiplegic upper limb and hand to a greater extent than the conventional therapy. The aim of this study was to investigate whether multiple sessions of 1-Hz rTMS facilitated the effect of RFEs on hemiplegic upper-limb function in chronic post-stroke patients. The study design was a randomized double-blinded crossover study. Eighteen patients with hemiplegia of the upper limb, were assigned to two groups: the motor-before-sham rTMS group, which performed m...
Source: Clinical Neurophysiology - July 16, 2013 Category: Neuroscience Authors: Shuji Matsumoto, Seiji Etoh, Kazumi Kawahira Tags: Society Proceedings Source Type: research

QEEG may uniquely inform and expedite decisions regarding intra-arterial clot retrieval in acute stroke
A recent review highlights that QEEG can uniquely inform ischaemic stroke (IS) management and treatment (). IS produces abnormal, slow EEG activity (delta and theta) and attenuation of faster (alpha and beta) activity (). One key QEEG index is “power” (signal intensity; units microvolts squared) of frequency-specific activity. Numerous studies indicate that global delta and alpha power measures and the delta/alpha ratio (DAR) can uniquely inform IS management (e.g., ). Broadly, DAR below 1 is normative whereas higher values are abnormal (). Several observations indicate that continuous EEG/QEEG can detect cerebral resp...
Source: Clinical Neurophysiology - April 19, 2013 Category: Neuroscience Authors: Nabeel Sheikh, Andrew Wong, Stephen Read, Alan Coulthard, Simon Finnigan Tags: Letters to the Editor Source Type: research

47. Botulinum toxin for the upper limb after stroke: Comparison between incobotulinumtoxin A, botulinum toxin drug free of complexing proteins, and conventional botulinum toxin formulation. A preliminary study
Botulinum toxin type A (BoNT/A) provides a valuable tool in the multi-modal treatment of spasticity. Incobotulinumtoxin A (InBoNT/A) is a highly purified BoNT/A agent, free of any complexing clostridial proteins.Clinical experience suggests that InBoNT/A is identical from efficacy, duration of therapeutic effect and tolerability profile. Our aim was to compare the effect of the CBoNT/A vs InBoNT/A on spasticity of the upper limb, evaluated with Modificated Aswhort Scale (MAS), and on amplitude of compound motor action potentials (CMAP) of biceps muscle in patients after brain stroke. A randomized, double-blind, parallel-gr...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: C. Cesaretti, A. Grippo, A. Vettori, T. Atzori, C. Baldini, C. Falsini, M. Martini, R. Carrai, A. Pizzi Tags: Society Proceedings Source Type: research