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Source: Clinical Neurophysiology
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Total 347 results found since Jan 2013.
P 168. TMS neurophysiology and interventional rTMS in children with perinatal stroke: Safety and tolerability in the PLASTIC CHAMPS trial
Introduction/Question: Perinatal stroke causes hemiplegic cerebral palsy and lifelong disability. TMS can define neurophysiology and central therapeutic targets while rTMS carries therapeutic potential in adult stroke but have not been applied to the more plastic developing brain. Ipsilateral projections from the unlesioned hemisphere to the affected hand are prominent in this population and the effects of non-lesioned inhibitory rTMS are unknown.Methods: PLASTIC CHAMPS is a randomized, blinded, factorial clinical trial of rTMS and constraint therapy (CIMT) to enhance upper extremity function in children (6–18years) with...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: T. Rajapakse, O. Kirton, J. Roe, A. Kirton Tags: Society Proceedings Source Type: research
P 240. Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following sequential bilateral non-invasive neuromodulation by theta burst magnetic stimulation
Conclusions: Described sequential bilateral physiologically balanced TMS modulation of activation of the language related areas of both hemispheres may result in considerable and rather fast language benefits in chronic nfA patients. Whether this approach is better than usual unilateral stimulation requires further studies.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: S. Filipovic, V. Stevanovic, I. Avramovic, M. Jelic, I. Avramovic, A. Jeremic, K. Kacar, S. Milanovic, L. Konstantinovic, J. Vuksanovic Tags: Society Proceedings Source Type: research
56. Effects of deep repetitive transcranial magnetic stimulation (rTMS) on motor function of paretic lower limb in chronic sub-cortical stroke: A pilot study
Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a promising intervention for treatment of stroke patients. The purpose of this double-blind placebo-controlled crossover study was to assess the efficacy of 20Hz rTMS delivered with H-coil on lower limb (LL) motor function in patients with chronic (>6months) subcortical stroke. Nine patients received both real and sham rTMS in a random sequence. rTMS treatments were composed of 11 sessions (administered over 3-weeks) and were separated by a 4-week wash-out period. LL functions were assessed by the Fugl-Meyer LL scale (FM-LL), the 10-meters walking t...
Source: Clinical Neurophysiology - October 21, 2013 Category: Neuroscience Authors: R. Chieffo, S. De Prezzo, E. Houdayer, A. Nuara, L. Straffi, F. Spagnolo, D.Dalla Libera, G.Di Maggio, E. Coppi, L. Ferrari, M. Sessa, M. Comola, A. Zangen, G. Comi, L. Leocani Tags: Society Proceedings Source Type: research
Reliability of lower limb motor evoked potentials in stroke and healthy populations: How many responses are needed?
Highlights: Abstract: Objective: To determine the intra- and inter-session reliability of motor evoked potential (MEP) size parameters in the lower limb of patients with stroke, focussing on the number of MEPs collected and the method of measuring MEP size.Methods: Transcranial magnetic stimulation was used to elicit MEPs in the soleus muscle of patients with stroke (n=13) and age-matched healthy participants (n=13) during low level muscle activation. Two sets of 10 responses were collected in the first session and a further 10 responses collected in a second session held 7days later. Four MEP size measurements were made u...
Source: Clinical Neurophysiology - October 7, 2013 Category: Neuroscience Authors: Gwyn N. Lewis, Nada Signal, Denise Taylor Tags: Movement, Motor Control and Movement Disorders Source Type: research
Priming sensorimotor cortex to enhance task-specific training after subcortical stroke
Conclusion: Primary motor cortex iTBS not only modulates M1 corticospinal excitability but also increases M1 receptiveness to sensory input.Significance: Priming with iTBSiM1 may enhance ipsilesional sensorimotor integration and facilitate better quality sensorimotor training after subcortical stroke.
Source: Clinical Neurophysiology - December 23, 2013 Category: Neuroscience Authors: Suzanne J. Ackerley, Cathy M. Stinear, P. Alan Barber, Winston D. Byblow Tags: Neural Plasticity, Functional Adaptation and Recovery Source Type: research
Deficits in startle-evoked arm movements increase with impairment following stroke
Conclusions: We conclude that the task-inappropriate flexor activity likely results from cortical or corticospinal damage leading to an unsuppressed or hypermetric classic startle reflex that interrupts startReact elbow extension.Significance: Given startReact’s functional role in compensation during environmental disturbances, our results may have important implications for our understanding deficits in stroke survivor’s response to unexpected environmental disturbances.
Source: Clinical Neurophysiology - January 10, 2014 Category: Neuroscience Authors: Claire Fletcher Honeycutt, Eric Jon Perreault Tags: Movement, Motor Control and Movement Disorders Source Type: research
106. Deep repetitive transcranial magnetic stimulation (rTMS) with H-coil coupled with cycling in chronic lower limb dysfuncion after stroke: A randomized, placebo-controlled, crossover study
Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a promising intervention for treatment of post-stroke deficits. We evaluated the feasibility, safety and efficacy of excitatory Hz rTMS with H-coil over the leg motor areas combined with active cycling on paretic lower limb motor function in chronic post-stroke. rTMS was delivered with the H-coil targeting the lower limbs (real or sham for 11 sessions over 3weeks, with cross-over after 4weeks wash-out, in 12 subjects with first stroke more than 6months before.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Chieffo, F. Giatsidis, E. Houdayer, M. Fichera, A. Nuara, E. Coppi, L. Ferrari, G. Di Maggio, R. Santangelo, A. Poggi, M. Sessa, M. Comola, A. Zangen, G. Comi, L. Leocani Source Type: research
1. Epileptic seizures in pediatric stroke: Data from the Italian Registry for Childhood Thrombosis
According to data from the Italian Registry for Childhood Thrombosis (R.I.T.I.), in about half cases diagnosis of pediatric stroke occurs after 24h from clinical onset (Baggio et al., SINP2013). The aim of the present study was to evaluate the frequency of seizures at stroke onset and their correlation with time to diagnosis in the pediatric stroke patients in the R.I.T.I. We selected the R.I.T.I. children with first acute arterial (AIS) or venous (CSVT) cerebral infarction occurring between January 2007 and June 2012; we studied prevalence, characteristics and recurrence of epileptic seizures, focusing on diagnostic delay.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: L. Baggio, S. Sartori, M. Nosadini, C. Gentilomo, P. Saracco, M. Agostini, B. Bassi, A. Palmieri, A.M. Laverda, P. Simioni, A. Suppiej, per il G.I.R.T.I. (Gruppo Italiano Registro Trombosi Infantili) Source Type: research
Atypical cortical drive during activation of the paretic and nonparetic tibialis anterior is related to gait deficits in chronic stroke
Following a neurological injury, recovery of lower extremity control and the ability to walk is a primary goal of stroke patients (Bohannon et al. 1991). However, many individuals are left with long term disability of functional ambulation following stroke, despite current standard rehabilitation (Bohannon et al. 1991). Gains in neuroscience research over the last several decades have enhanced our understanding of structural changes in the brain that may underlie functional disability following stroke (Kleim and Jones 2008).
Source: Clinical Neurophysiology - June 18, 2015 Category: Neuroscience Authors: Jacqueline A. Palmer, Alan R. Needle, Ryan T. Pohlig, Stuart A. Binder-Macleod Source Type: research
Repetitive transcranial magnetic stimulation for rehabilitation of post-stroke dysphagia: A randomized, double-blind clinical trial
Dysphagia is a common and potential fatal complication following stroke (Martino et al., 2005). It afflicts a great number of patients with hemispheric stroke (Martino et al., 2005) and brainstem infarction (Horner et al., 1991). Post-stroke dysphagia is associated with an increased risk for mortality, and it may lead to severe complications including malnutrition, dehydration and aspiration pneumonia (Teasell et al., 1994; Dziewas et al., 2004; Martino et al., 2005). Most patients recover from dysphagia within a few weeks, but the extent of recovery in swallowing varies widely from patient to patient.(Martino et al., 2005).
Source: Clinical Neurophysiology - December 10, 2015 Category: Neuroscience Authors: Juan Du, Fang Yang, Ling Liu, Jingze Hu, Biyang Cai, Wenhua Liu, Gelin Xu, Xinfeng Liu Source Type: research
ID 297 – Changes in finger tapping-related desynchronization during motor stroke recovery
Complex mechanisms underlying stroke recovery and modulations of associated brain activities are still far to be well elucidated. Here we investigated the potential effects of motor stroke recovery on finger tapping-related (FTR) brain dynamics by using high-power EEG with 128 channels and 2048Hz sampling rate. A follow-up study was carried out on six patients with ischemic stroke. Patients were instructed to perform finger tapping with their right or left index finger at a pace determined by a visual cue.
Source: Clinical Neurophysiology - February 11, 2016 Category: Neuroscience Authors: B. Weiss, J. Körmendi, A. Papp, M. Dombovári, Z. Nagy Source Type: research
Parietomotor connectivity in the contralesional hemisphere after stroke: a paired-pulse TMS study
Stroke is the main cause of acquired disability in adults. Upper limb paresis is one of the most frequent symptoms after stroke; the recovery of upper limb function is often problematic but constitutes a key factor in personal autonomy. Spatial neglect (defined as a failure to acknowledge or explore stimuli towards the contralesional side) (Heilman et al. 2000) is another challenging consequence of stroke, since it slows recovery and impairs activities of daily living (Di Monaco et al. 2011). In fact, spatial neglect is a frequent consequence of lesions in the right hemisphere - especially those affecting the inferior pari...
Source: Clinical Neurophysiology - February 27, 2017 Category: Neuroscience Authors: Etienne Allart, Arnaud Delval, Alexandre Caux-Dedeystere, Julien Labreuche, Romain Viard, Renaud Lopes, Herv é Devanne Source Type: research
Physiological arousal accompanying postural responses to external perturbations after stroke
Neuromuscular control of standing balance is known to be impaired after stroke (Garland et al. 2009). Response to surface translations have characterized the postural reactions of people post-stroke as being asymmetrical favoring the non-paretic leg (Marigold et al. 2004; van Asseldonk et al. 2006), accompanied by muscle activation which is delayed, and of decreased amplitude, in the paretic limb with poor intra-limb muscle coordination (Badke and Duncan 1983; Marigold and Eng 2006). In particular, the plantarflexor muscles in people post-stroke demonstrate impaired responses to external perturbations (Pollock et al.
Source: Clinical Neurophysiology - March 17, 2017 Category: Neuroscience Authors: C.L. Pollock, M.G. Carpenter, M.A. Hunt, A. Gallina, T.M. Vieira, T.D. Ivanova, Garland SJ Source Type: research
Applying a pelvic corrective force induces forced use of the paretic leg and improves paretic leg EMG activities of individuals post-stroke during treadmill walking
Walking dysfunction is one of the commonly reported physical limitations after stroke (Perry et al., 1995). Individuals with post-stroke hemiparesis typically demonstrate slow gait velocity, reduced stride and step length, and both decreased period of stance and increased period of swing of the paretic leg (Balaban and Tok, 2014; Patterson et al., 2010a). As walking dysfunction can increase the risk of falls (Hausdorff et al., 2001), restrict functional mobility and negatively affect quality of life (Maclean et al., 2000; Perry et al., 1995; Schmid et al., 2007), an important goal of stroke rehabilitation is to improve sym...
Source: Clinical Neurophysiology - July 31, 2017 Category: Neuroscience Authors: Chao-Jung Hsu, Janis Kim, Rongnian Tang, Elliot J. Roth, William Z. Rymer, Ming Wu Source Type: research
P 165 Incidence, clinical characteristics and longterm course of headache in patients with stroke (DMKG multicenter study)
Post stroke headache is a symptom which is generally not further differentiated. According to previous European and American studies, it is a common phenomenon. Nevertheless, other symptoms of stroke, such as palsy or aphasia, are dominating clinical assessments. However, the symptom “headache” can be an essential part of the clinical picture as in subarachnoid bleeding or cerebral venous thrombosis and it is unclear which risk factors modulate the symptoms and the occurrence of headache in stroke.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: S. Dietrich, A. D üring, D. Rothkirch, F. Filippopulos, O. Eren, T. Dresler, T. Buchwald, A. Straube, S. Zierz, G. Goßrau, T. Kraya Tags: Poster Source Type: research
