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Source: Clinical Neurophysiology

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Total 347 results found since Jan 2013.

P 181. Impact of offline transcranial direct current stimulation on consolidation of motor sequence learning in healthy elderly subjects
Conclusions: Offline application of anodal tDCS over M1 post training improves consolidation of motor sequence learning in elderly subjects until at least 22h post training. Further studies are needed to investigate the potential benefit of offline-tDCS in motor learning in healthy elderly and stroke patients.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: M. Wegscheider, J.-J. Rumpf, C. Fricke, D. Weise, J. Classen Tags: Society Proceedings Source Type: research

FV 1. Perilesional activation in poststroke language recovery
Poststroke aphasia recovery evolves in time. Increased perilesional activity associated with treatment-related language improvements has been confirmed in the chronic phase (Fridriksson et al., 2011), but has not yet been systematically demonstrated during the early phases of stroke recovery. The pathophysiology of stroke suggests that perilesional reorganisation evolves within days, lasting for months after stroke, while increased neuronal excitability might provide a basis for perilesional neuroplasticity (Schiene et al., 1999).
Source: Clinical Neurophysiology - August 5, 2016 Category: Neuroscience Authors: A. Stockert, J. Klingbeil, M. Wawrzyniak, K. Wrede, D. Saur Tags: Orals – Functional Imaging Source Type: research

S3-3. Clinical application of electroencephalogram-based brain-machine interfaces
A large number of electroencephalogram-based brain-machine interface (BMI) systems developed by industry and academia are now available for neurorehabilitation. However, the lack of phase 1 –2 clinical trials for BMI interventions to post-stroke hemiplegia has been limited their treatment outcome. To test the safety and feasibility of BMI interventions, we conducted trials with a customly developed BMI system for patients with acute/subacute hemiparetic stroke. Four inpatients partic ipated in this study in the early phase (7–24 days from stroke onset).
Source: Clinical Neurophysiology - March 30, 2018 Category: Neuroscience Authors: Yasunari Hashimoto, Toshiyuki Kakui, Junichi Ushiba, Meigen Liu, Kyousuke Kamada, Tetsuo Ota Source Type: research

A cloudy story: Guillain–Barré syndrome concealed by a spontaneous intracerebral haemorrhage
We present a case of Guillain–Barré syndrome (GBS), probably associated with influenza vaccine, occurring in a patient some days after a spontaneous haemorrhagic stroke. A 79-year-old woman was admitted to the neurosurgery department after a sudden severe headache, dizziness, and progressive generalised weakness. She had a history of hypertension and paroxysmal atrial fibrillation in dicumarolic therapy. Head CT scan showed a haemorrhagic stroke in left cerebellum, with compression on the fourth ventricle.
Source: Clinical Neurophysiology - October 22, 2012 Category: Neuroscience Authors: V. Mantero, L. De Toni Franceschini, L. Abate, F. Villa, A. Patruno, S. Jann, G. Citerio Tags: Letters to the Editor Source Type: research

Toward a better dexterity: Direction for future studies
Performing an accurate and adequate motor task is a key function in our daily living activities, and improvement of dexterity is a main concern especially in stroke survivors. Thus, the development of new strategies to improve motor learning and to promote stroke recovery is desirable.
Source: Clinical Neurophysiology - April 8, 2013 Category: Neuroscience Authors: Samar S. Ayache Tags: Editorials Source Type: research

S14-4. Possibility of a useful intervention of exercise induced by muscle fatigue to change excitabilities of corticospinal and cortico-cortical tracts for functional recovery in neurorehabilitation
Motor learning and synaptic plasticity in the cortex are enhanced by interventions that reduce the effectiveness of GABAergic intracortical inhibition. The disinhibition of SICI by muscle fatigue could enhance synaptic plasticity and improve the consolidation of motor learning. We found that the corticospinal excitability and SICI decrease after exhaustive muscle contraction or muscle fatigue. It seems possible that decreased SICI can enhance synaptic plasticity if motor learning or skill training is combined with muscle fatigue. Interestingly, fatigue in muscles on the opposite side of the body or in lower limb muscles re...
Source: Clinical Neurophysiology - July 16, 2013 Category: Neuroscience Authors: Atsuo Maruyama Tags: Society Proceedings Source Type: research

IS 39. Enhanced visuo-spatial and language learning with tDCS
Efficacy and effectiveness of training in conditions like chronic post-stroke aphasia or neglect, or neurodegenerative disorders like mild cognitive impairment (MCI) and Alzheimer’s disease, remain moderate only. Thus, novel strategies to enhance training success and overall behavioural outcome are urgently needed. Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation tool that is now being widely used in neuroscientific and clinical research in humans, modulating cortical excitability by application of weak electrical currents in the form of direct current brain polarization.In a series of st...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: A. Flöel, W. Suttorp, M. Meinzer, C. Breitenstein Tags: Society Proceedings Source Type: research

P 84. High-frequency neuronavigated cerebellar repetitive Transcranial Magnetic stimulation (rTMS) increases human pharyngeal motor cortex excitability
Conclusions: Our data show for the first time that high-frequency (10Hz) cerebellar stimulation can produce long-lasting increases in human pharyngeal motor cortex excitability, with larger and longer-lasting effects of the intervention primarily seen in the contralateral projection. Hence 10Hz cerebellar rTMS may play a therapeutic role in the treatment of dysphagia after hemispheric stroke.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: D. Vasant, S. Mistry, V. Jayasekeran, E. Michou, S. Hamdy Tags: Society Proceedings Source Type: research

P 126. Righthemispheric inhibitory rTMS in patients with letfsided brain infarcts: Effect on cerebral blood flow using PET and speech performance
Discussion: rTMS with inhibitory effect on the rightsided homologous speech area plus speech therapy in patients with left sided brain infarcts and aphasia results in better recovery of language performance compared to patients who received speech therapy only.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: A. Hartmann, I. Rubi-Fessen, W.-D. Heiß, L. Kracht, J. Kessler, T. Rommel Tags: Society Proceedings Source Type: research

P 229. Transcranial Laser Stimulation-A New Method for Non-Invasive Modulation of Cortical Excitability
Conclusions: The M1 excitability was found to be reduced after TLS in dose dependent manner. These findings may give insight into the mechanisms of nirLLL effects in the human cerebral cortex, also suggesting more suitable applications of TLS in clinical settings.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: S. Filipovic, M. Jelic, A. Jeremic, V. Stevanovic, S. Milanovic, L. Konstantinovic Tags: Society Proceedings Source Type: research

IS 39. Enhanced visuo-spatial and language learning with tDCS
Efficacy and effectiveness of training in conditions like chronic post-stroke aphasia or neglect, or neurodegenerative disorders like mild cognitive impairment (MCI) and Alzheimer’s disease, remain moderate only. Thus, novel strategies to enhance training success and overall behavioural outcome are urgently needed. Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation tool that is now being widely used in neuroscientific and clinical research in humans, modulating cortical excitability by application of weak electrical currents in the form of direct current brain polarization.In a series of st...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: A. Flöel, W. Suttorp, M. Meinzer, C. Breitenstein Tags: Society Proceedings Source Type: research

P 84. High-frequency neuronavigated cerebellar repetitive Transcranial Magnetic stimulation (rTMS) increases human pharyngeal motor cortex excitability
Conclusions: Our data show for the first time that high-frequency (10Hz) cerebellar stimulation can produce long-lasting increases in human pharyngeal motor cortex excitability, with larger and longer-lasting effects of the intervention primarily seen in the contralateral projection. Hence 10Hz cerebellar rTMS may play a therapeutic role in the treatment of dysphagia after hemispheric stroke.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: D. Vasant, S. Mistry, V. Jayasekeran, E. Michou, S. Hamdy Tags: Society Proceedings Source Type: research

P 126. Righthemispheric inhibitory rTMS in patients with letfsided brain infarcts: Effect on cerebral blood flow using PET and speech performance
Discussion: rTMS with inhibitory effect on the rightsided homologous speech area plus speech therapy in patients with left sided brain infarcts and aphasia results in better recovery of language performance compared to patients who received speech therapy only.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: A. Hartmann, I. Rubi-Fessen, W.-D. Heiß, L. Kracht, J. Kessler, T. Rommel Tags: Society Proceedings Source Type: research

P 229. Transcranial Laser Stimulation-A New Method for Non-Invasive Modulation of Cortical Excitability
Conclusions: The M1 excitability was found to be reduced after TLS in dose dependent manner. These findings may give insight into the mechanisms of nirLLL effects in the human cerebral cortex, also suggesting more suitable applications of TLS in clinical settings.
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: S. Filipovic, M. Jelic, A. Jeremic, V. Stevanovic, S. Milanovic, L. Konstantinovic Tags: Society Proceedings Source Type: research