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Source: Clinical Neurophysiology

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Total 347 results found since Jan 2013.

Cortical activation and inter-hemispheric sensorimotor coherence in individuals with arm dystonia due to childhood stroke
Motor disorders following childhood stroke are common (Lynch and Nelson, 2001), yet are insufficiently studied (Bejot et al., 2012). Of the observed post-stroke motor sequelae, childhood dystonia is the most frequently occurring disorder (Bejot et al., 2012). Dystonia, as it occurs in children, is defined as a movement disorder in which involuntary sustained or intermittent muscle contractions cause twisting and repetitive movements, abnormal postures, or both (Sanger et al., 2010). Post-stroke dystonia is most commonly observed on the side of the body contralateral to the stroke, and is referred to as hemidystonia.
Source: Clinical Neurophysiology - November 14, 2014 Category: Neuroscience Authors: Sahana N. Kukke, Ana Carolina de Campos, Diane Damiano, Katharine E. Alter, Nicholas Patronas, Mark Hallett Source Type: research

Multiple sessions of transcranial direct current stimulation and upper extremity rehabilitation in stroke: A review and meta-analysis
Stroke is a health concern worldwide and one of the main causes of disability (Kolominsky-Rabas et al., 2001; Albert and Kesselring, 2012). Motor impairment is the main cause of disability after stroke, leading to major health problems (Boggio et al., 2007; Clarke, 1999). In Europe, stroke costs around 64.1 billion euros and in the United Kingdom, around £8.9 billion per annum is spent on community care and rehabilitation of people with stroke (Saka et al., 2009; Gustavsson et al., 2011). At six months, 33% to 66% of people with Upper Extremity (UE) impairments do not present with functional upper limb function and only 5...
Source: Clinical Neurophysiology - May 4, 2015 Category: Neuroscience Authors: L. Tedesco Triccas, J.H. Burridge, A.M. Hughes, R.M. Pickering, M. Desikan, J.C. Rothwell, G. Verheyden Source Type: research

Effects of Non-Invasive Brain Stimulation on Post-Stroke Dysphagia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Studies report that 50% to 81% of people who have a stroke experience swallowing problems (Hamdy, 2010; Meng et al., 2000). This impact is staggering when the cost implications and morbidity of post-stroke dysphagia are considered. Stroke patients with dysphagia cost more to treat (about $4,510 more per patient than a stroke patient without dysphagia) because their hospital stay is nearly doubled, they require more therapy, and they have more complications with worse outcomes (Bonilha et al., 2014; Altman et al., 2010).
Source: Clinical Neurophysiology - May 8, 2015 Category: Neuroscience Authors: Jessica M. Pisegna, Asako Kaneoka, William G. Pearson, Sandeep Kumar, Susan E. Langmore Source Type: research

Do quiet standing centre of pressure measures within specific frequencies differ based on ability to recover balance in individuals with stroke?
Falls risk is increased in individuals with stroke compared to age-matched healthy individuals, and falls are one of the most frequent complications experienced during post-stroke recovery (Batchelor et al., 2012). Up to 73% of individuals with stroke fall following their return to community living after discharge from rehabilitation (Weerdesteyn et al., 2008), and individuals with stroke are 2-4 times more likely to suffer a fall-related injury compared to age-matched controls (O’Loughlin et al., 1993; Graafmans et al., 1996; Jørgensen et al., 2002).
Source: Clinical Neurophysiology - March 19, 2016 Category: Neuroscience Authors: Alison Schinkel-Ivy, Jonathan C. Singer, Elizabeth L. Inness, Avril Mansfield Source Type: research

Bilateral changes in muscle architecture of physically active people with chronic stroke: a quantitative muscle ultrasound study
Stroke is primarily regarded as a central nervous system (CNS) disorder, but post-stroke structural changes in skeletal muscles have been described. Imaging techniques such as Dual Energy X-ray Absorptiometry (DEXA) and Computed Tomography (CT) have revealed atrophy in several paretic side muscles of stroke survivors (English et al., 2010; Scherbakov et al., 2015). In addition to atrophy, increased intramuscular fat has been found in hemiparetic muscles of post-stroke patients (Ryan et al., 2002, Klein et al., 2010, Ryan et al., 2011).
Source: Clinical Neurophysiology - November 9, 2016 Category: Neuroscience Authors: Frank Berenpas, Anne-Marieke Martens, Vivian Weerdesteyn, Alexander C. Geurts, Nens van Alfen Source Type: research

PB 23 Factors predicting global cognitive ability 6month after stroke – preliminary results from the Phys-Stroke trial
Stroke is one of the most frequent causes of chronic and often severe language and motor impairments. Moreover, stroke increases the risk of developing cognitive impairments or even dementia over time (Pendlebury and Rothwell, 2009). Although recent studies investigated predictors of cognitive decline after stroke, several questions remain. In particular, it needs to be clarified whether therapies applied during the rehabilitation phase may reduce or even prevent cognitive decline.
Source: Clinical Neurophysiology - September 8, 2017 Category: Neuroscience Authors: T. Rackoll, K. Prehn, C. N àjera, L. Doppelbauer, A. Flöel Tags: Poster Blitz Source Type: research

Corticomuscular coherence in the acute and subacute phase after stroke
Stroke results from critically reduced blood flow to the brain tissue due to bleeding or obstruction of arteries. Globally, stroke remains a major cause of disability despite advances in preventive treatment and in acute management (Hankey, 2017). The most common impairment caused by stroke is motor disability affecting approximately 80% of the patients, most frequently seen as hemiparesis (Langhorne et al., 2009). Spontaneous recovery may occur in the following weeks and months after stroke and can be facilitated through rehabilitation involving exercise (Maulden et al., 2005).
Source: Clinical Neurophysiology - September 22, 2017 Category: Neuroscience Authors: Lisbeth Hoejkjaer Larsen, Ivan Chrilles Zibrandtsen, Troels Wienecke, Troels Wesenberg Kjaer, Mark Schram Christensen, Jens Bo Nielsen, Henning Langberg Source Type: research

PB10. Apraxic deficits in sub-acute right hemisphere stroke result from deficient allo-centric visuo-spatial processing
While visuo-spatial deficits are well characterized cognitive sequelae of right hemisphere (RH) stroke, apraxic deficits in RH stroke remain poorly understood. Likewise, very little is known about the association between apraxic and visuo-spatial deficits in RH stroke or about the putative common or differential pathophysiology underlying these deficits.Therefore, we examined the behavioral and lesion patterns of apraxic deficits (pantomime of object use and bucco-facial imitation) and visuo-spatial deficits (line bisection and letter cancellation tasks) in 50 sub-acute RH stroke patients.
Source: Clinical Neurophysiology - July 10, 2018 Category: Neuroscience Authors: S.D. Ubben, G.R. Fink, S. Kaesberg, E. Kalbe, J. Kessler, S. Vossel, P.H. Weiss Source Type: research

Processing of emotional words after stroke: An electrophysiological study
Conclusions: The neurophysiological processing of affective speech in aphasia has been revealed. This opens up the interpretation of these results to the critical assessment and therapeutic identification of emotional language in people with aphasia.Significance: This study has implications not just for aphasia but allows for further exploration of other neurological conditions.
Source: Clinical Neurophysiology - April 12, 2013 Category: Neuroscience Authors: E. Ofek, S.C. Purdy, G. Ali, T. Webster, N. Gharahdaghi, C.M. McCann Tags: Psychophysiology and Psychopathology Source Type: research

IS 27. Brain stimulation in stroke therapy
Non-invasive brain stimulation has shown its potential to modulate brain plasticity and enhance the effects of training in humans (Zimerman et al., Ann Neurol; 2012). Endeavour has been made to utilize brain stimulation in neurological diseases to enhance adaptive processes and prevent potential maladaptive ones. First studies presented evidence that non-invasive brain stimulation might not only transiently improve functions of the paretic hand, but can also modulate processes of learning (Zimerman et al., Stroke; 2012), a basis to achieve longer lasting effects. Based on this enhancement of functional recovery of both, se...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: F.C. Hummel Tags: Society Proceedings Source Type: research

P 155. Serial anodal tDCS over V1 induces long-term effects on colour discrimination in V4 measured in the unimpaired hemifield of patients with occipital stroke
Conclusion: Long-term modulation in colour perception following serial anodal tDCS may represent evidence of inducible long-term plasticity in distantly connected components of the visual system (V1 and V4) in patients with occipital stroke measured in the unimpaired hemifield. This builds on studies describing the immediate effects of tDCS in the visual system in healthy volunteers. The temporal dynamics of serial anodal tDCS seem to interact with learning processes, and may yield potential support for neuroplastic adaptation processes following cerebral lesions. Future studies should examine the long-term outcomes and dy...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: R. Dargie, M. Olma, J. Behrens, A. Kraft, K. Irlbacher, M. Fahle, S. Brandt Tags: Society Proceedings Source Type: research

P 168. TMS neurophysiology and interventional rTMS in children with perinatal stroke: Safety and tolerability in the PLASTIC CHAMPS trial
Introduction/Question: Perinatal stroke causes hemiplegic cerebral palsy and lifelong disability. TMS can define neurophysiology and central therapeutic targets while rTMS carries therapeutic potential in adult stroke but have not been applied to the more plastic developing brain. Ipsilateral projections from the unlesioned hemisphere to the affected hand are prominent in this population and the effects of non-lesioned inhibitory rTMS are unknown.Methods: PLASTIC CHAMPS is a randomized, blinded, factorial clinical trial of rTMS and constraint therapy (CIMT) to enhance upper extremity function in children (6–18years) with...
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: T. Rajapakse, O. Kirton, J. Roe, A. Kirton Tags: Society Proceedings Source Type: research

P 240. Improvement of language functions in a chronic non-fluent post-stroke aphasic patient following sequential bilateral non-invasive neuromodulation by theta burst magnetic stimulation
Conclusions: Described sequential bilateral physiologically balanced TMS modulation of activation of the language related areas of both hemispheres may result in considerable and rather fast language benefits in chronic nfA patients. Whether this approach is better than usual unilateral stimulation requires further studies.
Source: Clinical Neurophysiology - September 1, 2013 Category: Neuroscience Authors: S. Filipovic, V. Stevanovic, I. Avramovic, M. Jelic, I. Avramovic, A. Jeremic, K. Kacar, S. Milanovic, L. Konstantinovic, J. Vuksanovic Tags: Society Proceedings Source Type: research

IS 27. Brain stimulation in stroke therapy
Non-invasive brain stimulation has shown its potential to modulate brain plasticity and enhance the effects of training in humans (Zimerman et al., Ann Neurol; 2012). Endeavour has been made to utilize brain stimulation in neurological diseases to enhance adaptive processes and prevent potential maladaptive ones. First studies presented evidence that non-invasive brain stimulation might not only transiently improve functions of the paretic hand, but can also modulate processes of learning (Zimerman et al., Stroke; 2012), a basis to achieve longer lasting effects. Based on this enhancement of functional recovery of both, se...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: F.C. Hummel Tags: Society Proceedings Source Type: research

P 155. Serial anodal tDCS over V1 induces long-term effects on colour discrimination in V4 measured in the unimpaired hemifield of patients with occipital stroke
Conclusion: Long-term modulation in colour perception following serial anodal tDCS may represent evidence of inducible long-term plasticity in distantly connected components of the visual system (V1 and V4) in patients with occipital stroke measured in the unimpaired hemifield. This builds on studies describing the immediate effects of tDCS in the visual system in healthy volunteers. The temporal dynamics of serial anodal tDCS seem to interact with learning processes, and may yield potential support for neuroplastic adaptation processes following cerebral lesions. Future studies should examine the long-term outcomes and dy...
Source: Clinical Neurophysiology - September 19, 2013 Category: Neuroscience Authors: R. Dargie, M. Olma, J. Behrens, A. Kraft, K. Irlbacher, M. Fahle, S. Brandt Tags: Society Proceedings Source Type: research